WO2005041868A3 - Epidermal growth factor receptor modulation protects normal tissue - Google Patents

Epidermal growth factor receptor modulation protects normal tissue Download PDF

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Publication number
WO2005041868A3
WO2005041868A3 PCT/US2004/035019 US2004035019W WO2005041868A3 WO 2005041868 A3 WO2005041868 A3 WO 2005041868A3 US 2004035019 W US2004035019 W US 2004035019W WO 2005041868 A3 WO2005041868 A3 WO 2005041868A3
Authority
WO
WIPO (PCT)
Prior art keywords
normal tissue
growth factor
factor receptor
epidermal growth
receptor modulation
Prior art date
Application number
PCT/US2004/035019
Other languages
French (fr)
Other versions
WO2005041868A2 (en
Inventor
Susan Evans
Howard Thames
Original Assignee
Univ Ohio
Univ Texas
Susan Evans
Howard Thames
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio, Univ Texas, Susan Evans, Howard Thames filed Critical Univ Ohio
Publication of WO2005041868A2 publication Critical patent/WO2005041868A2/en
Publication of WO2005041868A3 publication Critical patent/WO2005041868A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators

Abstract

Methods are provided for protecting or rescuing normal tissue from damage are accomplished by elevating the levels or activity of EGFR in a patient in need of the same, for example, by administering to the patient EGFR protein, fragments thereof, or a pharmaceutical composition containing EGFR protein.
PCT/US2004/035019 2003-10-22 2004-10-22 Epidermal growth factor receptor modulation protects normal tissue WO2005041868A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51343503P 2003-10-22 2003-10-22
US60/513,435 2003-10-22

Publications (2)

Publication Number Publication Date
WO2005041868A2 WO2005041868A2 (en) 2005-05-12
WO2005041868A3 true WO2005041868A3 (en) 2005-12-01

Family

ID=34549277

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/035019 WO2005041868A2 (en) 2003-10-22 2004-10-22 Epidermal growth factor receptor modulation protects normal tissue

Country Status (1)

Country Link
WO (1) WO2005041868A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814308A (en) * 1996-03-26 1998-09-29 Zhang; Ke Methods for the treatment of gastrointestinal tract disorders
US5871724A (en) * 1990-06-25 1999-02-16 O.S.I. Pharmaceuticals Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871724A (en) * 1990-06-25 1999-02-16 O.S.I. Pharmaceuticals Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
US5814308A (en) * 1996-03-26 1998-09-29 Zhang; Ke Methods for the treatment of gastrointestinal tract disorders

Also Published As

Publication number Publication date
WO2005041868A2 (en) 2005-05-12

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