WO2005038000A3 - T cell epitopes useful in mycobacterium tuberculosis vaccine and as diagnostic tools and methods for identifying same - Google Patents

T cell epitopes useful in mycobacterium tuberculosis vaccine and as diagnostic tools and methods for identifying same Download PDF

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Publication number
WO2005038000A3
WO2005038000A3 PCT/US2004/033939 US2004033939W WO2005038000A3 WO 2005038000 A3 WO2005038000 A3 WO 2005038000A3 US 2004033939 W US2004033939 W US 2004033939W WO 2005038000 A3 WO2005038000 A3 WO 2005038000A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell epitopes
methods
mycobacterium tuberculosis
diagnostic tools
tuberculosis vaccine
Prior art date
Application number
PCT/US2004/033939
Other languages
French (fr)
Other versions
WO2005038000A2 (en
Inventor
Ole Lund
Claus Lundegaard
Morten Nielsen
Peder Worning
Robert J Deans
Soeren Buus
Soeren Brunak
Original Assignee
Pecos Labs Inc
Ole Lund
Claus Lundegaard
Morten Nielsen
Peder Worning
Robert J Deans
Soeren Buus
Soeren Brunak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pecos Labs Inc, Ole Lund, Claus Lundegaard, Morten Nielsen, Peder Worning, Robert J Deans, Soeren Buus, Soeren Brunak filed Critical Pecos Labs Inc
Publication of WO2005038000A2 publication Critical patent/WO2005038000A2/en
Publication of WO2005038000A3 publication Critical patent/WO2005038000A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Identification of T cell epitopes from M. tuberculosis using a neural networks, and T cell epitopes form M tuberculosis for diagnostic therapeutic uses.
PCT/US2004/033939 2003-10-17 2004-10-15 T cell epitopes useful in mycobacterium tuberculosis vaccine and as diagnostic tools and methods for identifying same WO2005038000A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51166603P 2003-10-17 2003-10-17
US60/511,666 2003-10-17

Publications (2)

Publication Number Publication Date
WO2005038000A2 WO2005038000A2 (en) 2005-04-28
WO2005038000A3 true WO2005038000A3 (en) 2005-11-03

Family

ID=34465261

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/033939 WO2005038000A2 (en) 2003-10-17 2004-10-15 T cell epitopes useful in mycobacterium tuberculosis vaccine and as diagnostic tools and methods for identifying same

Country Status (1)

Country Link
WO (1) WO2005038000A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102713629A (en) * 2009-11-20 2012-10-03 俄勒冈健康科学大学 Methods for detecting a mycobacterium tuberculosis infection

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2236608T3 (en) * 2005-10-04 2017-06-30 Soligenix, Inc. Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity
EP2793921B1 (en) 2011-12-22 2019-04-24 Children's Medical Center Corporation Saposin-a derived peptides and uses thereof
WO2014049436A1 (en) * 2012-09-27 2014-04-03 Idexx Laboratories, Inc. Method of detection of schmallenberg virus (sbv) and kit
CN106248934B (en) * 2016-08-25 2018-04-06 中国疾病预防控制中心传染病预防控制所 Antigen of mycobacterium tuberculosis albumen Rv0446c and its t cell epitope peptide application
CN111105843B (en) * 2019-12-31 2023-07-21 杭州纽安津生物科技有限公司 HLAI type molecule and polypeptide affinity prediction method
CN112002374B (en) * 2020-06-14 2022-04-22 北京臻知医学科技有限责任公司 MHC-I epitope affinity prediction method based on deep learning

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 16 December 2004 (2004-12-16), XP002992744, Database accession no. (ABU05715) *
NEILSEN ET AL: "Reliable prediction of T-cell epitopes using neural networks with novel sequence representations", PROTEIN SCIENCE, vol. 12, no. 5, 2003, pages 1007 - 1017, XP002992745 *
RAMMENSEE ET AL: "MHC Ligands and Peptide Motifs", LANDES BIOSCIENCE USA, 1997, pages 222 - 226, 237, XP008055384 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102713629A (en) * 2009-11-20 2012-10-03 俄勒冈健康科学大学 Methods for detecting a mycobacterium tuberculosis infection

Also Published As

Publication number Publication date
WO2005038000A2 (en) 2005-04-28

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