WO2005037756A3 - Nouveaux procedes de preparation de l’acide 4-[4-(4-methoxymethoxy-4’-methyl-biphenyl-2-yl)-but-3-ene-(e)-1-ynyl]-benzoïque - Google Patents

Nouveaux procedes de preparation de l’acide 4-[4-(4-methoxymethoxy-4’-methyl-biphenyl-2-yl)-but-3-ene-(e)-1-ynyl]-benzoïque Download PDF

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Publication number
WO2005037756A3
WO2005037756A3 PCT/EP2004/013741 EP2004013741W WO2005037756A3 WO 2005037756 A3 WO2005037756 A3 WO 2005037756A3 EP 2004013741 W EP2004013741 W EP 2004013741W WO 2005037756 A3 WO2005037756 A3 WO 2005037756A3
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WO
WIPO (PCT)
Prior art keywords
methoxymethoxy
ynyl
ene
biphenyl
methyl
Prior art date
Application number
PCT/EP2004/013741
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English (en)
Other versions
WO2005037756A2 (fr
Inventor
Christine Moureou
Franck Muller
Thibaud Biadatti
Jean-Claude Pascal
Original Assignee
Galderma Res & Dev
Christine Moureou
Franck Muller
Thibaud Biadatti
Jean-Claude Pascal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev, Christine Moureou, Franck Muller, Thibaud Biadatti, Jean-Claude Pascal filed Critical Galderma Res & Dev
Publication of WO2005037756A2 publication Critical patent/WO2005037756A2/fr
Publication of WO2005037756A3 publication Critical patent/WO2005037756A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C07C41/50—Preparation of compounds having groups by reactions producing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/57—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La présente invention concerne de nouveaux procédés de préparation de l’acide 4-[4-(4-méthoxyméthoxy-4’-méthyl-biphényl-2-yl)-but-3-ene (E)-1-ynyl]-benzoïque.
PCT/EP2004/013741 2003-10-17 2004-09-09 Nouveaux procedes de preparation de l’acide 4-[4-(4-methoxymethoxy-4’-methyl-biphenyl-2-yl)-but-3-ene-(e)-1-ynyl]-benzoïque WO2005037756A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0312155A FR2861068B1 (fr) 2003-10-17 2003-10-17 Nouveaux procedes de preparation de l'acide 4-[4-(4-methoxymethoxy-4'-methylbiphenyl-2-yl)-but-3ene-(e)- 1-ynyl]-benzoique
FR0312155 2003-10-17

Publications (2)

Publication Number Publication Date
WO2005037756A2 WO2005037756A2 (fr) 2005-04-28
WO2005037756A3 true WO2005037756A3 (fr) 2005-09-15

Family

ID=34385244

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/013741 WO2005037756A2 (fr) 2003-10-17 2004-09-09 Nouveaux procedes de preparation de l’acide 4-[4-(4-methoxymethoxy-4’-methyl-biphenyl-2-yl)-but-3-ene-(e)-1-ynyl]-benzoïque

Country Status (3)

Country Link
AR (1) AR046284A1 (fr)
FR (1) FR2861068B1 (fr)
WO (1) WO2005037756A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10300471B2 (en) 2013-10-08 2019-05-28 Chicago Discovery Solutions, Llc Ruthenium-catalyzed synthesis of biaryl compounds in water

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0879814A1 (fr) * 1997-05-23 1998-11-25 Centre International De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Composés triaromatiques, compositions les contenant et utilisations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0879814A1 (fr) * 1997-05-23 1998-11-25 Centre International De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Composés triaromatiques, compositions les contenant et utilisations

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE BEILSTEIN BEILSTEIN INSTITUTE FOR ORGANIC CHEMISTRY, FRANKFURT-MAIN, DE; XP002279149, Database accession no. 6089538 *
E.V. KOMISSAROVA ET AL, RUSS.J.GEN.CHEM., vol. 67, no. 3, 1997, pages 412 - 416 *
G.R. BROWN ET AL: "Synthesis and activity of a novel series of 3-biarylquinuclidine squalene synthase inhibitors", J.MED.CHEM., vol. 39, no. 15, 1996, pages 2971 - 2979, XP002279146 *
T.W. GREENE, P.G.M. WUTS: "Protective groups in organic synthesis third edition", 1999, JOHN WILEY & SONS, INC., ISSN: 0-471-22057-4, XP002279148 *
Y. OHSHIRO ET AL: "Reduction of gem-dibomides with diethyl phosphite", J.ORG.CHEM., vol. 46, no. 18, 1981, pages 3745 - 3747, XP002279147 *

Also Published As

Publication number Publication date
FR2861068A1 (fr) 2005-04-22
AR046284A1 (es) 2005-11-30
FR2861068B1 (fr) 2005-12-23
WO2005037756A2 (fr) 2005-04-28

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