WO2005035793A3 - Cckar markers and haplotypes associated with extreme weight conditions - Google Patents

Cckar markers and haplotypes associated with extreme weight conditions Download PDF

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Publication number
WO2005035793A3
WO2005035793A3 PCT/US2004/033192 US2004033192W WO2005035793A3 WO 2005035793 A3 WO2005035793 A3 WO 2005035793A3 US 2004033192 W US2004033192 W US 2004033192W WO 2005035793 A3 WO2005035793 A3 WO 2005035793A3
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WO
WIPO (PCT)
Prior art keywords
cckar
markers
haplotypes associated
weight conditions
extreme weight
Prior art date
Application number
PCT/US2004/033192
Other languages
French (fr)
Other versions
WO2005035793A2 (en
Inventor
Valur Emilsson
Jeffrey R Gulcher
Gudmundur Bragi Walters
Eric E Schadt
Der Ploeg Leonardus H T Van
Marc L Reitman
John R Lamb
Andreas W Sailer
Original Assignee
Decode Genetics Ehf
Rosetta Inpharmatics Llc
Merck & Co Inc
Valur Emilsson
Jeffrey R Gulcher
Gudmundur Bragi Walters
Eric E Schadt
Der Ploeg Leonardus H T Van
Marc L Reitman
John R Lamb
Andreas W Sailer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics Ehf, Rosetta Inpharmatics Llc, Merck & Co Inc, Valur Emilsson, Jeffrey R Gulcher, Gudmundur Bragi Walters, Eric E Schadt, Der Ploeg Leonardus H T Van, Marc L Reitman, John R Lamb, Andreas W Sailer filed Critical Decode Genetics Ehf
Publication of WO2005035793A2 publication Critical patent/WO2005035793A2/en
Publication of WO2005035793A3 publication Critical patent/WO2005035793A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Methods for diagnosis of obesity or a susceptibility or resistance to obesity based on detection of at risk haplotypes associated with human Cholecystokinin Type A Receptor gene are disclosed.
PCT/US2004/033192 2003-10-09 2004-10-08 Cckar markers and haplotypes associated with extreme weight conditions WO2005035793A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50992303P 2003-10-09 2003-10-09
US60/509,923 2003-10-09

Publications (2)

Publication Number Publication Date
WO2005035793A2 WO2005035793A2 (en) 2005-04-21
WO2005035793A3 true WO2005035793A3 (en) 2005-06-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/033192 WO2005035793A2 (en) 2003-10-09 2004-10-08 Cckar markers and haplotypes associated with extreme weight conditions

Country Status (1)

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WO (1) WO2005035793A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022006546A2 (en) 2019-10-07 2022-08-30 Kallyope Inc GPR119 AGONISTS

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09140398A (en) * 1995-11-21 1997-06-03 Shionogi & Co Ltd Detection of ii type diabetic gene
WO2000068209A2 (en) * 1999-05-06 2000-11-16 Glaxo Group Limited 1,5-benzodiazepine derivatives as cck-a receptor agonists
JP2002017369A (en) * 2000-07-07 2002-01-22 Mitsubishi Kagaku Bio-Clinical Laboratories Inc Method for detecting risk factor concerning obesity by cholecystokinin a receptor gene polymorphism
WO2002027008A1 (en) * 2000-09-26 2002-04-04 Biovitrum Ab Promoter sequences
WO2002034743A1 (en) * 2000-10-26 2002-05-02 Sanofi-Synthelabo Triazole derivatives and pharmaceutical compositions comprising them
WO2003063828A1 (en) * 2002-02-01 2003-08-07 Arizona Health Consulting Group, Llc Jojoba product for reducing weight, blood lipid levels and for the prevention and treatment of cancer
JP2004105145A (en) * 2002-09-20 2004-04-08 Japan Science & Technology Corp Method for easily determining genetic risk of cardiovascular disease, obesity and life-style related disease
WO2004061616A2 (en) * 2002-12-27 2004-07-22 Rosetta Inpharmatics Llc Computer systems and methods for associating genes with traits using cross species data

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09140398A (en) * 1995-11-21 1997-06-03 Shionogi & Co Ltd Detection of ii type diabetic gene
WO2000068209A2 (en) * 1999-05-06 2000-11-16 Glaxo Group Limited 1,5-benzodiazepine derivatives as cck-a receptor agonists
JP2002017369A (en) * 2000-07-07 2002-01-22 Mitsubishi Kagaku Bio-Clinical Laboratories Inc Method for detecting risk factor concerning obesity by cholecystokinin a receptor gene polymorphism
WO2002027008A1 (en) * 2000-09-26 2002-04-04 Biovitrum Ab Promoter sequences
WO2002034743A1 (en) * 2000-10-26 2002-05-02 Sanofi-Synthelabo Triazole derivatives and pharmaceutical compositions comprising them
WO2003063828A1 (en) * 2002-02-01 2003-08-07 Arizona Health Consulting Group, Llc Jojoba product for reducing weight, blood lipid levels and for the prevention and treatment of cancer
JP2004105145A (en) * 2002-09-20 2004-04-08 Japan Science & Technology Corp Method for easily determining genetic risk of cardiovascular disease, obesity and life-style related disease
WO2004061616A2 (en) * 2002-12-27 2004-07-22 Rosetta Inpharmatics Llc Computer systems and methods for associating genes with traits using cross species data

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
FUNAKOSHI A ET AL: "Gene structure of human cholecystokinin (CCK) type-A receptor: body fat content is related to CCK type-A receptor gene promoter polymorphism", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 466, no. 2-3, 28 January 2000 (2000-01-28), pages 264 - 266, XP004260881, ISSN: 0014-5793 *
INOUE H ET AL: "Human Cholecystokinin Type A Receptor Gene: Cytogenetic Localization, Physical Mapping, and Identification of Two Missense Variants in Patients with Obesity and Non-Insulin-Dependent Diabetes Mellitus (NIDDM)", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 42, no. 2, 1 June 1997 (1997-06-01), pages 331 - 335, XP004459301, ISSN: 0888-7543 *
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 10 31 October 1997 (1997-10-31) *
PATENT ABSTRACTS OF JAPAN vol. 2002, no. 05 3 May 2002 (2002-05-03) *
PATENT ABSTRACTS OF JAPAN vol. 2003, no. 12 5 December 2003 (2003-12-05) *
TAKATA YUTAKA ET AL: "Promoter analysis of human cholecystokinin type-A receptor gene.", JOURNAL OF GASTROENTEROLOGY, vol. 37, no. 10, October 2002 (2002-10-01), pages 815 - 820, XP002323108, ISSN: 0944-1174 *

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Publication number Publication date
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