WO2005021575A3 - Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties - Google Patents

Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties Download PDF

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Publication number
WO2005021575A3
WO2005021575A3 PCT/IB2004/003126 IB2004003126W WO2005021575A3 WO 2005021575 A3 WO2005021575 A3 WO 2005021575A3 IB 2004003126 W IB2004003126 W IB 2004003126W WO 2005021575 A3 WO2005021575 A3 WO 2005021575A3
Authority
WO
WIPO (PCT)
Prior art keywords
bacterial
signaling molecules
virulence properties
regulate
diseases
Prior art date
Application number
PCT/IB2004/003126
Other languages
French (fr)
Other versions
WO2005021575A2 (en
Inventor
Gregor Reid
Peter A Cadieux
John K Mccormick
Estelle Devilliard
Original Assignee
Gregor Reid
Peter A Cadieux
John K Mccormick
Estelle Devilliard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gregor Reid, Peter A Cadieux, John K Mccormick, Estelle Devilliard filed Critical Gregor Reid
Publication of WO2005021575A2 publication Critical patent/WO2005021575A2/en
Publication of WO2005021575A3 publication Critical patent/WO2005021575A3/en
Priority to US11/363,915 priority Critical patent/US20070036776A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to composition and methods of employing said composition for treating or preventing microbial associated infections and diseases. More particularly the present invention relates to bacterial proteins, peptides and amino acids which are by-products of bacteria, in particular Lactobacillus and more specifically Lactobacillus strains GR-1 and RC-14, in compositions that can treat and prevent microbial-associated infections and diseases, by altering, for example, down-regulating, virulence properties of pathogenic organisms.
PCT/IB2004/003126 2003-08-29 2004-08-27 Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties WO2005021575A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/363,915 US20070036776A1 (en) 2003-08-29 2006-02-28 Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49896003P 2003-08-29 2003-08-29
US60/498,960 2003-08-29

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/363,915 Continuation-In-Part US20070036776A1 (en) 2003-08-29 2006-02-28 Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties

Publications (2)

Publication Number Publication Date
WO2005021575A2 WO2005021575A2 (en) 2005-03-10
WO2005021575A3 true WO2005021575A3 (en) 2005-05-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/003126 WO2005021575A2 (en) 2003-08-29 2004-08-27 Bacterial signaling molecules that down-regulate pathogenic bacterial virulence properties

Country Status (2)

Country Link
US (1) US20070036776A1 (en)
WO (1) WO2005021575A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE033223T2 (en) * 2010-11-29 2017-11-28 Eurochit Danuta Kruszewska New nanoproduct useful in prophilaxis, diagnostics and medical and veterinary treatment
CN103687604A (en) 2011-03-01 2014-03-26 群体创新有限责任公司 Materials and methods for treating conditions associated with pathogenic biofilm
FR2982367B1 (en) * 2011-11-08 2013-12-27 Biomerieux Sa METHOD FOR DETECTING HEMOLYSINE DELTA OF STAPHYLOCOCCUS AUREUS BY MASS SPECTROMETRY DIRECTLY FROM A BACTERIAL POPULATION
KR20150027152A (en) * 2012-05-29 2015-03-11 다누타 크루셰프스카 Nanoproduct comprising lactobacillus reuteri dan080 useful in prophylaxis and medicine, both human and veterinary and medical use of the same
EP2674162A1 (en) * 2012-05-29 2013-12-18 Danuta Kruszewska Nanoproduct comprising lactobacillus reuteri dan080 useful in prophylaxis and medicine, both human and veterinary and medical use of the same
AU2014407509B2 (en) 2014-09-30 2020-09-03 Kimberly-Clark Worldwide, Inc. Synergistic prebiotic composition
BR112017004118B1 (en) 2014-09-30 2022-04-12 Kimberly-Clark Worldwide, Inc Creped paper web, multi-layer creped paper product, and, method of making a prebiotic creped paper web
EP3378485A1 (en) * 2017-03-24 2018-09-26 Nomad Bioscience GmbH Bacteriocins for control of salmonella enterica
CN111172055B (en) * 2019-03-14 2022-06-10 南京农业大学 Lactobacillus paracasei LHZ-1 and application thereof in removing deoxynivalenol
CN110577897A (en) * 2019-09-27 2019-12-17 中国药科大学 Method for rapidly separating lactobacillus reuteri in intestinal tract of mouse

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051552A (en) * 1996-05-30 2000-04-18 Urex Biotech, Inc. Lactobacillus therapies
WO2000071139A2 (en) * 1999-05-25 2000-11-30 Gregor Reid Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0759469T3 (en) * 1995-08-07 2003-06-23 Nestle Sa bacteriocin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051552A (en) * 1996-05-30 2000-04-18 Urex Biotech, Inc. Lactobacillus therapies
WO2000071139A2 (en) * 1999-05-25 2000-11-30 Gregor Reid Lactobacillus compositions and methods for preventing wound infections and biofilm formation on implantable surgical devices

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRURBERG ET AL.: "Pheromone-induced production of antimicrobial peptides in Lactobacillus", MOL. MICROBIOL., vol. 26, no. 2, October 1997 (1997-10-01), pages 347 - 360 *
CADIEUX ET AL.: "Lactobacillus strains and vaginal ecology", JAMA, vol. 287, no. 15, April 2002 (2002-04-01), pages 1940 - 1941 *
HOLO ET AL.: "Plantaracin W from Lactobacillus plantarum belongs to a new family of two peptide lantibiotics", MICROBIOLOGY, vol. 147, no. PT3, March 2001 (2001-03-01), pages 643 - 651 *
MACK ET AL.: "Probiotics inhibit enteropathogenic E. coli adherence in virto by inducing intestinal mucin gene expression", AM. J. PHYSIOL., vol. 276, no. 4, April 1999 (1999-04-01), pages G941 - 950 *
REID ET AL.: "Selection of lactobacillus strains for urogenital probiotic applications", J. INFECT. DISEASES, vol. 183, no. SUPPL1, March 2001 (2001-03-01), pages S77 - 80 *

Also Published As

Publication number Publication date
WO2005021575A2 (en) 2005-03-10
US20070036776A1 (en) 2007-02-15

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