WO2005015239A3 - Method for n-terminal labeling of proteins - Google Patents

Method for n-terminal labeling of proteins Download PDF

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Publication number
WO2005015239A3
WO2005015239A3 PCT/US2004/025464 US2004025464W WO2005015239A3 WO 2005015239 A3 WO2005015239 A3 WO 2005015239A3 US 2004025464 W US2004025464 W US 2004025464W WO 2005015239 A3 WO2005015239 A3 WO 2005015239A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
terminal labeling
terminal
labeling
prepare
Prior art date
Application number
PCT/US2004/025464
Other languages
French (fr)
Other versions
WO2005015239A2 (en
Inventor
Samie R Jaffrey
Original Assignee
Cornell Res Foundation Inc
Samie R Jaffrey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc, Samie R Jaffrey filed Critical Cornell Res Foundation Inc
Publication of WO2005015239A2 publication Critical patent/WO2005015239A2/en
Publication of WO2005015239A3 publication Critical patent/WO2005015239A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A method to prepare N-terminal modified peptides is provided.
PCT/US2004/025464 2003-08-07 2004-08-06 Method for n-terminal labeling of proteins WO2005015239A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49315903P 2003-08-07 2003-08-07
US60/493,159 2003-08-07

Publications (2)

Publication Number Publication Date
WO2005015239A2 WO2005015239A2 (en) 2005-02-17
WO2005015239A3 true WO2005015239A3 (en) 2005-03-24

Family

ID=34135206

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/025464 WO2005015239A2 (en) 2003-08-07 2004-08-06 Method for n-terminal labeling of proteins

Country Status (1)

Country Link
WO (1) WO2005015239A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12019078B2 (en) 2016-05-02 2024-06-25 Encodia, Inc. Macromolecule analysis employing nucleic acid encoding

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019089836A1 (en) 2017-10-31 2019-05-09 Encodia, Inc. Kits for analysis using nucleic acid encoding and/or label
WO2020198264A1 (en) * 2019-03-26 2020-10-01 Encodia, Inc. Modified cleavases, uses thereof and related kits
US11427814B2 (en) 2019-03-26 2022-08-30 Encodia, Inc. Modified cleavases, uses thereof and related kits
AU2020267119A1 (en) 2019-04-30 2021-11-18 Encodia, Inc. Methods for preparing analytes and related kits

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002093131A2 (en) * 2001-05-14 2002-11-21 The Institute For Systems Biology Methods for isolating and labeling sample molecules
WO2003056343A2 (en) * 2001-12-22 2003-07-10 Peter James Method for protein expression analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002093131A2 (en) * 2001-05-14 2002-11-21 The Institute For Systems Biology Methods for isolating and labeling sample molecules
WO2003056343A2 (en) * 2001-12-22 2003-07-10 Peter James Method for protein expression analysis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TAO W ANDY ET AL: "Advances in quantitative proteomics via stable isotope tagging and mass spectrometry.", CURRENT OPINION IN BIOTECHNOLOGY. FEB 2003, vol. 14, no. 1, February 2003 (2003-02-01), pages 110 - 118, XP009018515, ISSN: 0958-1669 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12019078B2 (en) 2016-05-02 2024-06-25 Encodia, Inc. Macromolecule analysis employing nucleic acid encoding

Also Published As

Publication number Publication date
WO2005015239A2 (en) 2005-02-17

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