WO2005010175A1 - Method for producing l-lysine or l-threonine using escherichia bacteria having attnuated malic enzyme activity - Google Patents
Method for producing l-lysine or l-threonine using escherichia bacteria having attnuated malic enzyme activity Download PDFInfo
- Publication number
- WO2005010175A1 WO2005010175A1 PCT/JP2004/011220 JP2004011220W WO2005010175A1 WO 2005010175 A1 WO2005010175 A1 WO 2005010175A1 JP 2004011220 W JP2004011220 W JP 2004011220W WO 2005010175 A1 WO2005010175 A1 WO 2005010175A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lysine
- malic enzyme
- threonine
- gene
- seq
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK04771247T DK1651758T3 (en) | 2003-07-29 | 2004-07-29 | Process for Preparation of L-Lysine or L-Threonine Using Escherichia Bacteria with Impaired Malic Enzyme Activity |
BRPI0413007A BRPI0413007B1 (en) | 2003-07-29 | 2004-07-29 | method of producing l-lysine or l-threonine |
DE602004014158T DE602004014158D1 (en) | 2003-07-29 | 2004-07-29 | PROCESS FOR THE PREPARATION OF L-LYSINE OR L-THREONINE USING ESCHERICHIA BACTERIA WITH ATTRACTIONED MALATENZYMAKTIVITY |
PL04771247T PL1651758T3 (en) | 2003-07-29 | 2004-07-29 | Method for producing l-lysine or l-threonine using escherichia bacteria having attenuated malic enzyme activity |
EP04771247A EP1651758B1 (en) | 2003-07-29 | 2004-07-29 | Method for producing l-lysine or l-threonine using escherichia bacteria having attenuated malic enzyme activity |
KR1020057024543A KR101208480B1 (en) | 2003-07-29 | 2005-12-21 | - - Method for producing L-lysine or L-threonine using Escherichia bacteria having attenuated malic enzyme activity |
US11/275,437 US7306933B2 (en) | 2003-07-29 | 2006-01-03 | Method for producing L-lysine or L-threonine |
US11/877,726 US8030036B2 (en) | 2003-07-29 | 2007-10-24 | Method for producing L-lysine or L-threonine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003-202842 | 2003-07-29 | ||
JP2003202842 | 2003-07-29 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/275,437 Continuation US7306933B2 (en) | 2003-07-29 | 2006-01-03 | Method for producing L-lysine or L-threonine |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005010175A1 true WO2005010175A1 (en) | 2005-02-03 |
Family
ID=34100609
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/011220 WO2005010175A1 (en) | 2003-07-29 | 2004-07-29 | Method for producing l-lysine or l-threonine using escherichia bacteria having attnuated malic enzyme activity |
PCT/JP2004/011212 WO2005010794A2 (en) | 2003-07-29 | 2004-07-29 | Method for determining metabolic flux affecting substance production |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2004/011212 WO2005010794A2 (en) | 2003-07-29 | 2004-07-29 | Method for determining metabolic flux affecting substance production |
Country Status (14)
Country | Link |
---|---|
US (3) | US7306933B2 (en) |
EP (2) | EP1651758B1 (en) |
JP (2) | JP4894134B2 (en) |
KR (2) | KR101073370B1 (en) |
CN (2) | CN100577799C (en) |
AT (1) | ATE397059T1 (en) |
BR (2) | BRPI0413030A (en) |
DE (1) | DE602004014158D1 (en) |
DK (1) | DK1651758T3 (en) |
ES (1) | ES2305849T3 (en) |
PL (1) | PL1651758T3 (en) |
RU (1) | RU2337140C2 (en) |
WO (2) | WO2005010175A1 (en) |
ZA (1) | ZA200510144B (en) |
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WO2007017710A1 (en) * | 2005-08-11 | 2007-02-15 | Metabolic Explorer | Process for the preparation of aspartate and derived amino acids like lysine, threonine, isoleucine, methionine, homoserine, or valine employing a microorganism with enhanced isocitrate lyase and/or malate synthase expression |
WO2007086618A1 (en) | 2006-01-30 | 2007-08-02 | Ajinomoto Co., Inc. | L-amino acid producing bacterium and method of producing l-amino acid |
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WO2007125954A1 (en) | 2006-04-28 | 2007-11-08 | Ajinomoto Co., Inc. | Microorganism capable of producing l-amino acid, and process for production of l-amino acid |
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WO2008090770A1 (en) | 2007-01-22 | 2008-07-31 | Ajinomoto Co., Inc. | Microorganism capable of producing l-amino acid, and method for production of l-amino acid |
WO2008093829A1 (en) | 2007-02-01 | 2008-08-07 | Ajinomoto Co., Inc. | Method for production of l-amino acid |
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WO2008114721A1 (en) | 2007-03-14 | 2008-09-25 | Ajinomoto Co., Inc. | Microorganism capable of producing l-glutamic acid-type amino acid, and method for production of amino acid |
WO2008133131A1 (en) | 2007-04-16 | 2008-11-06 | Ajinomoto Co., Inc. | Method for production of organic acid |
WO2008133161A1 (en) | 2007-04-17 | 2008-11-06 | Ajinomoto Co., Inc. | Method for production of acidic substance having carboxyl group |
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WO2009072562A1 (en) | 2007-12-06 | 2009-06-11 | Ajinomoto Co., Inc. | Process for production of organic acid |
DE102008049533A1 (en) | 2007-09-27 | 2009-06-18 | Ajinomoto Co., Inc. | A method for producing amino acids using a bacterium of the family Enterobacteriaceae |
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WO2009093703A1 (en) | 2008-01-23 | 2009-07-30 | Ajinomoto Co., Inc. | Method of producing l-amino acid |
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WO2009104731A1 (en) | 2008-02-21 | 2009-08-27 | 味の素株式会社 | L-cysteine-producing bacterium, and method for production of l-cysteine |
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