WO2005005403A3 - Process for preparation of oxetan-2-ones - Google Patents

Process for preparation of oxetan-2-ones Download PDF

Info

Publication number
WO2005005403A3
WO2005005403A3 PCT/IB2004/002305 IB2004002305W WO2005005403A3 WO 2005005403 A3 WO2005005403 A3 WO 2005005403A3 IB 2004002305 W IB2004002305 W IB 2004002305W WO 2005005403 A3 WO2005005403 A3 WO 2005005403A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxetan
ones
preparation
present
relates
Prior art date
Application number
PCT/IB2004/002305
Other languages
French (fr)
Other versions
WO2005005403A2 (en
Inventor
Yatendra Kumar
Mohan Prasad
Keshav Deo
Anand Pandey
Kilol Patel
Original Assignee
Ranbaxy Lab Ltd
Yatendra Kumar
Mohan Prasad
Keshav Deo
Anand Pandey
Kilol Patel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Yatendra Kumar, Mohan Prasad, Keshav Deo, Anand Pandey, Kilol Patel filed Critical Ranbaxy Lab Ltd
Priority to EP04743966A priority Critical patent/EP1651627A2/en
Publication of WO2005005403A2 publication Critical patent/WO2005005403A2/en
Publication of WO2005005403A3 publication Critical patent/WO2005005403A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Abstract

The present invention relates to a process for the preparation of diastereomerically and enantiomerically pure oxetan-2-ones. The present invention also relates to a process for the preparation of ester derivatives of oxetan-2-ones. The present invention further relates to compounds prepared by such processes.
PCT/IB2004/002305 2003-07-15 2004-07-15 Process for preparation of oxetan-2-ones WO2005005403A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04743966A EP1651627A2 (en) 2003-07-15 2004-07-15 Process for preparation of oxetan-2-ones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN900DE2003 2003-07-15
IN900/DEL/2003 2003-07-15

Publications (2)

Publication Number Publication Date
WO2005005403A2 WO2005005403A2 (en) 2005-01-20
WO2005005403A3 true WO2005005403A3 (en) 2005-04-07

Family

ID=34044520

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/002305 WO2005005403A2 (en) 2003-07-15 2004-07-15 Process for preparation of oxetan-2-ones

Country Status (2)

Country Link
EP (1) EP1651627A2 (en)
WO (1) WO2005005403A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006035296A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Process for the preparation of an orlistat derivative useful as reference standard in the determination of the purity of orlistat and process for the preparation of orlistat
US20090171104A1 (en) * 2005-10-05 2009-07-02 Killol Patel Process for the preparation of orlistat
US8680298B2 (en) * 2007-06-06 2014-03-25 Ranbaxy Laboratories Limited Process for the preparation of orlistat
CN112625009A (en) * 2020-12-18 2021-04-09 植恩生物技术股份有限公司 Refining method of orlistat key intermediate

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202824A (en) * 1978-05-25 1980-05-13 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Physiologically active derivatives of esterastin
US4931463A (en) * 1984-12-21 1990-06-05 Hoffmann-La Roche Inc. Oxetanones
US4983746A (en) * 1984-12-21 1991-01-08 Hoffmann-La Roche Inc. Oxetanones and process for their production
US5412110A (en) * 1992-07-06 1995-05-02 Chemie Linz Gesellschaft M.B.H. Enzymatic process to separate racemic mixtures of delta valerolactones
US5902886A (en) * 1997-01-23 1999-05-11 Schick; Hans Method for synthesizing oxetan-2-ones and intermediates for their preparation
EP1127886A1 (en) * 2000-02-04 2001-08-29 F. Hoffmann-La Roche Ag Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one
WO2002032850A1 (en) * 2000-10-16 2002-04-25 John Jason Gentry Mullins Process for making (2s, 3s, 5s) oxetanone derivatives

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202824A (en) * 1978-05-25 1980-05-13 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Physiologically active derivatives of esterastin
US4931463A (en) * 1984-12-21 1990-06-05 Hoffmann-La Roche Inc. Oxetanones
US4983746A (en) * 1984-12-21 1991-01-08 Hoffmann-La Roche Inc. Oxetanones and process for their production
US5412110A (en) * 1992-07-06 1995-05-02 Chemie Linz Gesellschaft M.B.H. Enzymatic process to separate racemic mixtures of delta valerolactones
US5902886A (en) * 1997-01-23 1999-05-11 Schick; Hans Method for synthesizing oxetan-2-ones and intermediates for their preparation
EP1127886A1 (en) * 2000-02-04 2001-08-29 F. Hoffmann-La Roche Ag Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one
WO2002032850A1 (en) * 2000-10-16 2002-04-25 John Jason Gentry Mullins Process for making (2s, 3s, 5s) oxetanone derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ISHIHARA, TAKASHI; ICHIHARA, KAZUYOSHI, YAMANAKA, HIROKI: "Highly Selective Aldol Reaction of Metal Enolates of alpha-Fluoropropanethioates with Aldehydes Affording erythro-alpha-Fluoro-alpha-methyl-beta-hydroxy Alkanethionates", TETRAHEDRON LETTERS, vol. 36, no. 45, 1995, pages 8267 - 8270, XP002300391 *

Also Published As

Publication number Publication date
EP1651627A2 (en) 2006-05-03
WO2005005403A2 (en) 2005-01-20

Similar Documents

Publication Publication Date Title
WO2001028996A3 (en) Pyrrolidine derivatives, their preparation and their use as inhibitors of neuraminidases
WO2005113558A3 (en) Simple stereocontrolled synthesis of salinosporamide a
WO2004099132A3 (en) Process for the preparation of trans-isomers of diphenylazetidinone derivatives
AU2003282383A1 (en) A process for the preparation of high purity escitalopram
AU2001272504A1 (en) 4-alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof
AU2003258667A1 (en) Method for the production by fermentation of sulphur-containing fine chemicals (metf)
AU2003299300A1 (en) METHOD FOR THE PRODUCTION OF R-Alpha-LIPOIC ACID BY FERMENTATION
WO2005005403A3 (en) Process for preparation of oxetan-2-ones
AU6578400A (en) Novel method for preparing benzoperhydroisoindole compounds
AU2003252467A1 (en) Process for preparation of 1,3-benzodioxole-2-spiro- cycloalkane derivatives
WO2005056563A3 (en) Process for the preparation of thiazolopyrimidines
WO2007057767A3 (en) Amino acid derivatives
AU2002367890A1 (en) Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate
WO2007030848A3 (en) Non-fluorescent chlorophyll catabolites
WO2005054175A3 (en) New process for the preparation of nitrooxyderivatives of paracetamol
WO2004011449A3 (en) Method for the production of phenylalanine derivatives
AU2003224495A1 (en) Process for the preparation of enantiomerically enriched compounds
WO2003007872A3 (en) Process for the preparation of citalopram hydrobromide
WO2004034983A3 (en) Preparation of triazospiro compounds
AU2003282267A1 (en) An improved process for the preparation of cefpodoxime proxetil
WO2004037170A3 (en) Process for making spirolactone compounds
AU2003272080A1 (en) Novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate
WO2003080567A3 (en) Intermediates for the synthesis of discodermolide and related analogues and methods for their preparation
AU2003259544A1 (en) Process for the preparation of gabapentin
WO2004041830A3 (en) An improved process for the preparation of biotin

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 560/DELNP/2006

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2004743966

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2004743966

Country of ref document: EP