WO2005001033A3 - Tolerance induction and maintenance in hematopoietic stem cell allografts - Google Patents

Tolerance induction and maintenance in hematopoietic stem cell allografts Download PDF

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Publication number
WO2005001033A3
WO2005001033A3 PCT/US2004/016444 US2004016444W WO2005001033A3 WO 2005001033 A3 WO2005001033 A3 WO 2005001033A3 US 2004016444 W US2004016444 W US 2004016444W WO 2005001033 A3 WO2005001033 A3 WO 2005001033A3
Authority
WO
WIPO (PCT)
Prior art keywords
maintenance
stem cell
hematopoietic stem
tolerance induction
cell allografts
Prior art date
Application number
PCT/US2004/016444
Other languages
French (fr)
Other versions
WO2005001033A2 (en
Inventor
Maria Z Siemionow
Original Assignee
Cleveland Clinic Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/443,281 external-priority patent/US20040028677A1/en
Application filed by Cleveland Clinic Foundation filed Critical Cleveland Clinic Foundation
Publication of WO2005001033A2 publication Critical patent/WO2005001033A2/en
Publication of WO2005001033A3 publication Critical patent/WO2005001033A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

Provided are methods and compositions for the induction and maintenance of tolerance in hematopoietic stem cell allografts.
PCT/US2004/016444 2003-05-22 2004-05-24 Tolerance induction and maintenance in hematopoietic stem cell allografts WO2005001033A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47255303P 2003-05-22 2003-05-22
US10/443,281 2003-05-22
US60/472,553 2003-05-22
US10/443,281 US20040028677A1 (en) 2002-05-22 2003-05-22 Chimeric allograft tolerance induction, monitoring and maintenance

Publications (2)

Publication Number Publication Date
WO2005001033A2 WO2005001033A2 (en) 2005-01-06
WO2005001033A3 true WO2005001033A3 (en) 2005-07-28

Family

ID=33555008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/016444 WO2005001033A2 (en) 2003-05-22 2004-05-24 Tolerance induction and maintenance in hematopoietic stem cell allografts

Country Status (1)

Country Link
WO (1) WO2005001033A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010089400A1 (en) 2009-02-06 2010-08-12 Mymetics Corporation Novel gp41 antigens
US9725689B2 (en) 2010-10-08 2017-08-08 Terumo Bct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
CN105992816B (en) 2013-11-16 2018-04-17 泰尔茂比司特公司 Cell amplification in bioreactor
JP6783143B2 (en) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド Passive replenishment of medium
CN106715676A (en) 2014-09-26 2017-05-24 泰尔茂比司特公司 Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3464565A4 (en) 2016-05-25 2020-01-01 Terumo BCT, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
JP7393945B2 (en) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド cell proliferation
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040028677A1 (en) * 2002-05-22 2004-02-12 Siemionow Maria Z. Chimeric allograft tolerance induction, monitoring and maintenance

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040028677A1 (en) * 2002-05-22 2004-02-12 Siemionow Maria Z. Chimeric allograft tolerance induction, monitoring and maintenance

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SIEMIONOW ET AL.: "Induction of tolerance in composite-tissue allografts", TRANSPLANTATION, vol. 74, no. 9, 15 November 2002 (2002-11-15), pages 1211 - 1217, XP002987907 *

Also Published As

Publication number Publication date
WO2005001033A2 (en) 2005-01-06

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