WO2004108192A1 - Chemical liquid supply control method, chemical liquid supply control device used for the method, and chemical liquid dosing set using the device - Google Patents

Chemical liquid supply control method, chemical liquid supply control device used for the method, and chemical liquid dosing set using the device Download PDF

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Publication number
WO2004108192A1
WO2004108192A1 PCT/JP2004/007503 JP2004007503W WO2004108192A1 WO 2004108192 A1 WO2004108192 A1 WO 2004108192A1 JP 2004007503 W JP2004007503 W JP 2004007503W WO 2004108192 A1 WO2004108192 A1 WO 2004108192A1
Authority
WO
WIPO (PCT)
Prior art keywords
spool
chemical liquid
injection line
chemical
liquid supply
Prior art date
Application number
PCT/JP2004/007503
Other languages
French (fr)
Japanese (ja)
Inventor
Mitsuru Hasegawa
Satoshi Yoshise
Shinsuke Takahashi
Original Assignee
Nipro Corporation
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nipro Corporation, Schering Aktiengesellschaft filed Critical Nipro Corporation
Priority to JP2005506750A priority Critical patent/JP4600280B2/en
Publication of WO2004108192A1 publication Critical patent/WO2004108192A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/18—General characteristics of the apparatus with alarm

Definitions

  • Chemical solution supply control method Chemical solution supply control method, chemical solution supply control device used in the method, and chemical solution administration set using the device
  • the present invention relates to a drug solution supply control method, a drug solution supply control device used in the method, and a drug solution administration set using the device.
  • a method of administering a drug solution to a patient by using a syringe includes connecting an injection needle that can be connected to a syringe tip, an indwelling needle already indwelled in a blood vessel, or a so-called injection line that extends a catheter force. There is a way to do that. At this time, there is a problem if a blood vessel is previously secured, that is, if the tip of the injection needle connected to the injection line is securely placed in the blood vessel.
  • the gasket may be located near the open end of the syringe barrel, or may be subjected to high-pressure steam sterilization.
  • the stopper may be inserted from the open end to prevent the gasket from coming off. In these cases, the plunger cannot be pulled due to the structure. For this reason, in the above, it is not possible to confirm the securing of blood vessels, and therefore, the above-mentioned problem caused by the lack of blood vessels may inevitably occur.
  • the maximum infusion rate is determined for some types of drug solutions, but conventionally, when the injection speed of the drug solution is higher than the normal injection speed, the operator is required to set the maximum injection speed. In many cases, it is not possible to notify the patient or to stop the injection of the drug solution. Therefore, in the above case, the patient is burdened.
  • a syringe or an injection line may be covered with a protective wall in order to prevent the practitioner from being exposed to radiation.
  • the reflux cannot be visually confirmed.
  • the problem to be solved is that "the patient who administers the drug solution is inside a CT scanner or an MRI scanner," or "the syringe that administers the drug solution is a prefilled syringe.” Or ⁇ when administering a drug solution via a catheter inserted deep inside the patient's body '' or ⁇ when administering radiopharmaceuticals, a syringe or In the case where the injection line is also covered with a protective wall, ”it means that it was not possible to easily detect whether blood vessels were secured or not.
  • An object of the present invention is to provide a chemical solution supply control method that solves the above problems, a chemical solution supply control device used in the method, and a chemical solution administration set using the device.
  • the features of the control method are as follows: ( a ) a housing interposed between the chemical solution supply means and the injection line; and (b) a slidably provided in the axial direction in the housing and the housing. (C) a chemical liquid supply stopping means for stopping the supply of the chemical liquid from the chemical liquid supply means to the injection line and / or an injection line from the chemical liquid supply means.
  • the problem is to use a malfunction notification means for notifying a malfunction related to the supply of the drug solution to the system, and to activate the drug solution stop means and / or the malfunction notification means when the injection line is closed.
  • the housing is provided with an opposing portion which is opposed to one end surface in the axial direction of the spool, and which is defined as an inflow portion for operation between the end surface and the end surface.
  • the supply stopping means supplies the liquid medicine from the liquid supply means or the injection line to the inflow portion for operation, and slides the spool in the axial direction, thereby stopping the supply of the liquid medicine from the liquid supply means to the injection line.
  • the operating means applies an operating force in the axial direction to the spool while the injection line is filled with the liquid.
  • the spool slides and liquid in the injection line is sucked into the housing.
  • the injection line is closed, the spool does not slide and the spool does not slide. The engagement between the pool and the operating means may be released.
  • the liquid in the injection line may be sucked between the end face of the spool, which is opposite to the operation direction, and the housing.
  • the chemical liquid supply control device is characterized by (a) a housing interposed between the chemical liquid supply means and the injection line, and (b) a slidably provided in the housing in the axial direction. And a spool for intermittently connecting the chemical liquid supply means and the injection line by sliding in the axial direction, and (c) a chemical liquid supply stop means and / or a malfunction notification means.
  • a housing interposed between the chemical liquid supply means and the injection line
  • a spool for intermittently connecting the chemical liquid supply means and the injection line by sliding in the axial direction
  • a chemical liquid supply stop means and / or a malfunction notification means When the line is closed and when the pressure of Z or the drug solution is higher than the set pressure, it is a means to stop the supply of the drug solution from the drug solution supply means to the injection line, and the malfunction notification means is from the drug solution supply means to the injection line. In other words, it is a means of reporting a problem with
  • the housing is provided with an opposing portion facing the one end surface in the axial direction of the spool, and an opposing portion between the end surface and the end surface is defined as an operation inflow portion. Is supplied to the inflow portion for operation, and the spool is slid in the axial direction.
  • the housing has (a) a spool hole, (b) an inflow port through which the chemical solution from the chemical solution supply means flows into the spool hole, and (c) an outflow port through which the chemical solution in the spool hole flows out to the injection line.
  • a spool is formed in the spool hole to connect the inflow port and the outflow port intermittently so as to be slidable in the axial direction, and when the pressure of the chemical solution rises when the inflow port and the outflow port are connected.
  • the pressure may be provided with a chemical liquid supply stopping means for sliding the spool to cut off the connection between the inflow port and the outflow port.
  • the spool has a pair of lands separated in the axial direction. The group between the lands may be a group connecting the inflow port and the outflow port, and the chemical solution supply stopping means may be formed in the spool to be a flow path for communicating the gnoreve and the operating inflow section. That.
  • the chemical liquid supply stopping means is formed in the housing and serves as an inlet-side operation port for communicating the chemical liquid supply means with the inflow portion for operation.
  • the inflow port may be used also as the inlet-side operation port.
  • the chemical liquid supply stopping means is formed in the housing and serves as an outlet-side operation port for communicating the injection line with the inflow portion for operation.
  • outflow port may be used also as the outlet-side operation port.
  • the facing portion may be an auxiliary portion made of an elastic material.
  • setting means for interrupting the connection between the drug solution supply means and the injection line may be provided.
  • the setting pressure of the setting means may be adjustable.
  • the housing has a spool operating means, and the housing has (a) a spool hole in which the spool is slidably provided in the axial direction, and (b) an inflow through which the chemical from the chemical solution supply means flows into the spool hole.
  • a port (c) an outflow port that is connected to the inflow port intermittently by sliding the spool, and allows the drug solution in the spool hole to flow out to the injection line, and (d) a drug solution in the injection line for operation. It has an operation port that flows into the spool, and the two are detachably engaged between the spool and the operating means, and the operating force of the operating means is set when the spool is operated in the direction away from the facing part. An engagement means for releasing the engagement when the operating force is exceeded may be provided.
  • the spool has a pair of lands which are spaced apart in the axial direction and are slidably provided in the spool direction in the axial direction, and between the lands is a gnorebe for connecting the inflow port and the outflow port.
  • the spool is: (a) a pair of small-diameter lands provided in the spool hole so as to be slid in the axial direction by being spaced apart in the axial direction; and (b) the axial direction of the two small-diameter lands and the spool.
  • both small-diameter lands and large-diameter lands may be provided separately.
  • the spool may be provided with a notifying unit that projects to the outside of the housing and notifies the shut-off when the connection between the chemical solution supply unit and the injection line is cut off.
  • the operating means includes (a) a lever pivotally supported by the housing and (b) a return panel for returning the lever after swinging to the original position, and the engaging means comprises (i) A circumferential groove formed in the spool, and (ii) an engaging groove formed in the lever and engaged with the circumferential groove so as to be removably engaged through elastic deformation.
  • ⁇ ⁇ ⁇ may be present.
  • the lever when the connection between the inflow port and the outflow port is cut off, the lever may be used as a notification unit for notifying the cutoff.
  • the housing may be provided with a cylindrical injection line mounting portion surrounding the outflow port, and the injection line mounting portion may be provided with a luer lock adapter connected to the injection line.
  • a housing is formed in (a) an axial direction in which a spool is slidably provided in an axial direction, and (b) a spool hole is formed in a side portion of a housing and a housing, and communicates with the spool hole.
  • an outflow port connected to the injection line, wherein the spool is connected to (i) a chemical liquid supply means and communicates with an inflow portion for operation; and (ii) a side portion of the spool. It may have an inflow port which is formed and communicates with the communication passage and the spool hole, and is connected to the outflow port intermittently by sliding the spool.
  • A a first member having a substantially cylindrical shape, a spool hole inside, a front end portion facing, and an inflow port formed in a side wall portion in a radial direction;
  • It has a substantially cylindrical shape that opens in both axial directions, and has a second member having a connection portion on the base side and an injection line mounting portion on the front end connected to the injection line, and the connection portion is the first member.
  • the inflow port is fixed to the member from the distal end side, and the inflow port is internally provided in the connection portion, and the inflow port may communicate with the injection line mounting portion via the gap between the first and second members.
  • a luer lock adapter connected to the injection line may be provided at the injection line mounting part.
  • the housing may be provided at a base end portion of the first member, and may have a lid for restricting sliding of the spool in the axial rearward direction.
  • first and third lands are arranged in the axial direction on the outer peripheral portion of the spool from the distal end portion to the proximal end portion, and a connection between the inflow port and the outflow port is provided between the first and second lands.
  • the connection between the 2nd and 3rd lands is always in communication with the inflow port, and when the inflow port is connected to the outflow port, the connection between the 2nd and 3rd lands.
  • a fourth land is provided on the outer peripheral portion of the spool on a base side with respect to the third land, The distance between the third and fourth lands may be larger than the distance between the connection position and the blocking position of the spool.
  • a through hole is formed in the spool in the axial direction, the base of the spool is a tip mounting portion on which the tip of the syringe is separably mounted, and the tip of the through hole is a communication passage.
  • setting means for setting a value of an external force necessary for sliding of the spool may be provided. Further, a setting value of the setting means may be adjustable.
  • the spool may be provided with a notifying portion that projects rearward in the axial direction of the housing when the connection between the inflow port and the outflow port is cut off, and notifies the above shutoff.
  • a feature of the medical solution administration set of the present invention is that it has a chemical solution supply control device and a chemical solution supply means.
  • the drug solution supply means may be a syringe for injection.
  • the syringe for injection may be a syringe filled with a drug solution.
  • the chemical solution supply means may be a drip bag.
  • the infusion bag may be a bag filled with a chemical solution.
  • the chemical supplied by the chemical supply means may be a contrast agent.
  • the contrast agent may be an MRI contrast agent.
  • the auxiliary portion made of the elastic material can assist the spool to slide to the blocking position.
  • the operating force for sliding the spool is increased, so that the practitioner can more reliably recognize that the operating mechanism is being operated.
  • the operator can easily recognize that the connection between the inflow port and the outflow port has been interrupted by visually recognizing the notification section or lever. S can.
  • FIG. 1 is a sectional view showing a first embodiment of the present invention.
  • FIG. 2 is an operation state diagram of FIG. 1.
  • FIG. 3 is a sectional view showing a second embodiment of the present invention.
  • FIG. 4 is an operation state diagram of FIG. 3.
  • FIG. 5 is a sectional view showing a third embodiment of the present invention.
  • FIG. 6 is an operation state diagram of the spool in FIG. 5.
  • FIG. 7 is an operation state diagram of the setting mechanism of FIG. 5.
  • FIG. 8 is a sectional view showing a fourth embodiment of the present invention.
  • FIG. 9 is an operation state diagram of FIG.
  • FIG. 10 is a sectional view showing a fifth embodiment of the present invention.
  • FIG. 11 is an operation state diagram of FIG.
  • FIG. 12 is a sectional view taken along line AA of FIG. 10.
  • FIG. 13 is a sectional view showing a sixth embodiment of the present invention.
  • FIG. 14 is an operation state diagram of FIG.
  • FIG. 15 is a sectional view showing a seventh embodiment of the present invention.
  • FIG. 16 is an operation state diagram of FIG.
  • FIG. 17 is a front view showing an eighth embodiment of the present invention.
  • FIG. 18 is a plan view of FIG.
  • FIG. 19 is a bottom view of FIG. 17.
  • FIG. 20 is a left side view of FIG. 17.
  • FIG. 23 is an operation state diagram of FIG.
  • FIG. 25 is a front sectional view showing a ninth embodiment of the present invention.
  • FIG. 26 is an operation state diagram of FIG.
  • FIG. 28 is a front sectional view showing a tenth embodiment of the present invention.
  • FIG. 29 is a side view showing an eleventh embodiment of the present invention.
  • FIG. 30 is an operational state diagram of FIG. 29.
  • FIG. 31 is a sectional view taken along line BB of FIG. 29.
  • FIG. 32 is a sectional view taken along line CC of FIG. 31.
  • FIG. 33 is a sectional view taken along the line DD in FIG. 30.
  • FIG. 34 is a longitudinal sectional view showing a twelfth embodiment of the present invention.
  • FIG. 35 is a side view showing a thirteenth embodiment of the present invention.
  • FIG. 36 is an operating state diagram of FIG.
  • FIG. 37 is a sectional view taken along line E—E in FIG. 35.
  • FIG. 38 is a sectional view taken along line F-F of FIG. 36, description of reference numerals
  • the present invention provides a chemical supply control method capable of easily detecting whether or not a blood vessel is secured and preventing leakage of a chemical outside a blood vessel, a chemical supply control device used in the method, and a device using the chemical supply control device.
  • a drug solution administration set is provided.
  • the chemical liquid supply control device includes a chemical liquid supply unit (chemical liquid supply line) (not shown) and an injection line (not shown). It is interposed between and has a housing 1, a spool (gasket) 2, and the like.
  • the drug solution supply means means a medical device for administering a drug solution into a blood vessel of a living body, and examples thereof include an injection syringe, an infusion bag, and an infusion bottle. It is not something to be done.
  • the drug solution supply means includes a drug solution-filled syringe (prefilled syringe), a drug solution-filled bag, a drug solution-filled drip bottle, and the like, which are already filled with the drug solution.
  • the drug solution is a solution, suspension, emulsion, or the like that is directly applied into the blood vessel of a living body through the skin or the like, and is a drug solution used for treatment or diagnosis of various diseases.
  • Nutrient solution, saline or other medical solution but not limited to Les ,.
  • Examples of the drug solution used for diagnosis of various diseases include contrast agents such as MRI contrast agents, X-ray contrast agents, and ultrasound contrast agents, and various diagnostic agents.
  • injection line an injection needle that can be attached to a syringe tip, an indwelling needle already indwelled in a blood vessel, a line that extends the force of a catheter, or the like is used.
  • injection also includes so-called “infusion” in which a large amount (100 ml or more) of a drug solution is administered for a long time.
  • the housing 1 is made of plastic and has a main body 4 and a lid 5.
  • the main body 4 is provided with a tubular (hollow) tubular portion (tubular portion) 7 which is disposed in the up-down direction and opens upward, and which will be described later on the right side from the middle part of the tubular portion 7 in the up-down direction.
  • a cylindrical (hollow) chip mounting portion 8 protruding so as to surround the inflow port 12 and a left side from a vertical middle portion of the cylindrical portion 7 so as to surround an outflow port 13 described later.
  • the provided cylindrical (hollow) injection line mounting portion 9 is integrally formed. Note that the tip mounting section 8 and the injection line mounting section 9 need not necessarily be aligned on the same straight line when viewed in plan, and may be installed at an angle in the circumferential direction of the cylindrical section 7. Les ,.
  • the inside of the tubular portion 7 is a spool hole 10 having a vertical axis and opening upward, and the bottom of the tubular portion 7 is a facing portion 11 facing the lower end surface of the spool 2. I have.
  • the tip mounting part 8 has a syringe (not shown) detachably mounted therein and has a three-way stopcock function (three-way stopcock).
  • the tip mounting part 8 opens at the right end and has a cylindrical part 7.
  • the inflow port 12 allows the chemical from the chemical supply means to flow into the spool hole 10 via the tip mounting portion 8.
  • a method of attaching a three-way cock (not shown) that can arbitrarily change the flow path of two or more kinds of chemicals to the tip mounting part 8 and a method of mounting the tip
  • a method in which the part 8 itself is a three-way cock is a three-way cock.
  • the reason why the tip mounting section 8 is provided with the three-way cock function is as follows. That is, even if the drug is successfully administered intravascularly (in most cases, it is administered without problems), serious allergic reactions such as a decrease in blood pressure may occur with the drug. In such a case, a quick response is required. In this case, if blood vessels are secured by the three-way cock function as in the present invention, it becomes possible to quickly perform emergency treatment by administration of various drugs such as steroids. [0026] The above allergic reaction may occur during the infusion of the drug solution, or may occur shortly after administration, so it is considered that it is desirable to perform the test using the three-way cock function. In addition, the role of the drug solution remaining on the administration line as a flush is important from the viewpoint of securing an appropriate dose when the amount of the drug solution to be administered is small.
  • the connecting portion of the chemical liquid supply means with the chip mounting portion 8 has a chip or a portion corresponding to the chip.
  • a tip or a portion corresponding to the tip may be provided between the chemical solution supply means and the tip mounting portion 8 to mount a catheter or the like.
  • the injection line mounting section 9 is provided with an injection line (not shown) detachably mounted, is disposed below the tip mounting section 8, is opened at the left end, and has a cylindrical section 7.
  • the outflow port 13 allows the drug solution in the spool hole 10 to flow out to the injection line mounting section 9, and is disposed below the inflow port 12.
  • a lock mechanism such as a Nore lock adapter is provided in the injection line mounting portion 9 so that the injection line and the injection line mounting portion 9 do not accidentally come off when the injection pressure of the drug solution is high.
  • a catheter, an injection needle, an indwelling needle, and the like are connected to the injection line mounting section 9.
  • the lid 5 is externally fitted to and fixed to the upper end of the cylindrical portion 7, and covers the upper end opening of the cylindrical portion 7.
  • An opening 15 is formed at the center of the lid so as to penetrate vertically. Have been.
  • the spool 2 is slidably provided in the spool hole 10 in the vertical direction (axial direction). As shown in FIG. 1, the lower end surface of the spool 2 comes into contact with the facing portion 11 of the housing 1 and As shown in FIG. 2, the connection position for connecting the inflow port 12 and the outflow port 13 and, as shown in FIG. 2, a position higher than the connection position and a blocking position for blocking the connection can be freely changed. It is communicated to part 15.
  • the constituent material of the spool 2 is not particularly limited as long as it is an elastic member that has been used as a power medical device using plastic, thermoplastic elastomer, silicon elastomer, butyl rubber, or the like.
  • the spool 2 includes a lower land 17, a small-diameter portion 18 having a diameter smaller than that of the lower land 17, an upper land 19 having substantially the same diameter as the lower land 17, and both lands 17. Notice that the diameter was smaller than 19
  • the part 20 is configured by being connected upward (integrally formed) in the above order.
  • the small diameter portion 18 may have the same diameter as the lands 17 and 19.
  • the lower end surface of the lower land 17 is opposed to the opposing portion 11 of the housing 1 in the up-down direction, and when the force spool 2 having the actuation inflow portion 21 between the two is in the connection position, the spool is in the connected position.
  • the lower end surface of 2 is in contact with the facing portion 11.
  • the upper and lower ends of the outer periphery of the lower land 17 and the lower end of the upper land 19 are provided with seal portions 2224 that abut (press) against the inner surface of the spool hole 10 to prevent liquid leakage.
  • the spool 2 can be held at an arbitrary sliding position.
  • an external force greater than the external force at the start of sliding (set external force) acts on the spool 2 in the vertical direction, Spool 2 is slidable. That is, the seal portion 2224 also has a function as a setting means for determining the above-mentioned external force at which the sliding starts.
  • the seal portion 2224 may be usually formed of a seal member which is formed integrally with the spool 2 and is formed as a force.
  • the outflow port 13 is located between the upper and lower seal portions 23 and 22 of the lower land 17 when the spool 2 is at the shut-off position.
  • a gnoreve (circumferential groove) 25 is formed between the lands 17 and 19 separated from each other in the axial direction, that is, the radially outer side of the small-diameter portion 18, and is always in communication with the inflow port 12. However, it communicates with the outflow port 13 only when the spool 2 is in the connection position.
  • the lower part of the small diameter portion 18 and the lower land 17 are provided with a chemical liquid supply stopping means (blocking means).
  • a chemical liquid supply stopping means blocking means. This means, when the inflow port 12 and the outflow port 13 are connected to each other, when the pressure of the chemical solution exceeds the set pressure (abnormal pressure), the spool 2 is slid by the pressure of the chemical solution, and the inflow port 12 Since the supply of the chemical solution is stopped by disconnecting the connection between the outlet port 13 and the outlet port 13, it is specifically constituted by a flow path 26 which is a bypass.
  • the chemical liquid supply stopping means may include the inflow section 21 for operation.
  • the flow path 26 connects the group 25 and the inflow section 21 for operation, and includes a vertical hole 27 and a horizontal hole 28.
  • the vertical hole 27 is formed in the lower center portion of the lower land 17 and the lower axial portion of the small-diameter portion 18 and opens downward at the lower end.
  • the horizontal hole 28 is formed in the lower part of the small diameter portion 18 in the front-rear direction.
  • the center part in the front-rear direction communicates with the upper end of the vertical hole 27, and both front and rear ends are opened in the front-rear direction. Note that only one of the front and rear ends of the horizontal hole 28 may be open.
  • the normal injection pressure equal to or lower than the set injection pressure of the drug solution, that is, the normal injection pressure of the drug solution due to the gauge of the syringe needle, the cross-sectional area of the syringe, etc. at the time of injection.
  • An upward external force acts on the spool 2 due to an increase in pressure, for example, an increase in the pressure of the chemical solution at the initial stage of sliding of the plunger of the syringe, or an increase in the pressure of the chemical solution due to a normal injection speed of the chemical solution.
  • the external force at the start of sliding of the spool 2 is larger than that of the spool 2.
  • a large abnormal injection pressure higher than the set injection pressure of the drug solution is applied to the spool 2 in the upward direction. It acts as an external force, but the external force at which the spool 2 starts sliding is smaller than this external force. That is, the sliding start external force is set to be larger than the normal external force acting on the spoonle 2 at the time of injection so that the spool 2 does not slide unexpectedly. Is considered small.
  • the upper surface of the upper land 19 contacts the lower end surface of the lid 5 when the spool 2 is at the blocking position.
  • the notification unit 20 constitutes a failure notification unit that reports a failure related to the supply of the chemical solution from the chemical solution supply unit to the injection line. When the chemical solution supply stop unit operates, the notification unit 20 reports this operation.
  • the notification unit 20 protrudes slightly upward from the housing 1 when the spool 2 is at the connection position (it may not be protruded), and largely protrudes from the housing 1 when the spool 2 is at the shut-off position.
  • the notification unit 20 is usually colored to ensure the visual recognition of the notification unit 20.
  • the sliding of the spool 2 or the operation of the notification section 20 accompanying the sliding can be changed into an electric, optical or acoustic signal to be notified.
  • Means for notifying by changing to an electric, optical or acoustic signal include a bell, a light bulb, a light emitting diode, a buzzer, a sound emitting plate, and the like.
  • an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment portion 9.
  • a tip of a syringe filled with a drug solution is mounted on the tip mounting section 8 as a drug solution supply means.
  • the spool 2 is at the connection position shown in FIG. 1, and the inflow port 12 and the outflow port 13 are connected by the group 25.
  • the plunger of the syringe Prior to injection, first, the plunger of the syringe is pressed, and the flow path to the patient, After filling the inside of the syringe mounting part 8, spool hole 10, injection line mounting part 9, and injection line with a drug solution and removing the air inside the so-called "priming", the injection needle of the injection line is moved to the patient. Puncture the blood vessels.
  • the case where the above priming is performed with a physiological saline is also used.
  • the spool 2 is held at the connection position as described below, so that the drug solution flows into the blood vessel and performs the usual injection. .
  • the normal injection pressure of the set injection pressure of the liquid medicine or less that is, the normal pressure of the liquid medicine due to the gauge of the needle of the syringe, the cross-sectional area of the syringe, etc. at the time of injection.
  • An upward external force acts on the lower end surface of the spool 2 due to a rise, for example, a rise in the pressure of the chemical solution at the initial stage of sliding of the plunger of the syringe, or an increase in the pressure of the chemical solution due to a normal injection speed of the chemical solution.
  • the sliding start external force of the spool 2 is set to be larger than this external force, there is no possibility that the spool 2 may slide unexpectedly.
  • the spool 2 slides upward, and the drug solution of the syringe continues to flow into the working inflow section 21 through the tip mounting section 8 and the outflow port 13, and the spool 2 is moved upward. 2, the connection between the inflow port 12 and the outflow port 13 is cut off, and the notification unit 20 protrudes greatly from the housing 1.
  • the plunger of the syringe cannot be pressed, and the drug solution is not forcibly injected into a portion that is not a necessary portion, so that the patient may not feel significant pain.
  • the patient will be able to smoothly receive the required medical treatment, It is possible to prevent additional medical activities such as medical treatment due to leakage to the outside, and it is expected that medical economics will be more efficient.
  • the practitioner can easily know the above-mentioned abnormality, that is, that no blood vessel is secured, at the hand side. Since the notification unit 20 protrudes greatly from the housing 1, the practitioner can easily visually recognize the notification unit, and thereby can easily know at hand that a blood vessel is not secured.
  • the chemical solution in the tip mounting portion 8 and the like can be returned to the syringe.
  • the chemical solution can be prevented from being wasted, and an increase in medical costs can be prevented. it can.
  • the pressure of the chemical solution in the inflow portion 21 for operation may drop, and the spool 2 may return to the connection position.
  • the notification unit 20 may be pressed downward to return the spool 2 to the connection position.
  • the chemical solution is also injected at a speed higher than the normal injection speed as described below. There is nothing. That is, when the injection speed of the drug solution becomes faster than the normal injection speed after the initial stage of the injection, a large abnormal injection pressure equal to or higher than the set injection pressure of the drug solution is applied to the spool 2 via the flow path 26 as described above. The upward external force acting on the lower end surface and acting on the spool 2 is equal to or greater than the external force at which the sliding starts. As a result, the spool 2 is in the shut-off position, and the injection of the chemical liquid cannot be performed.
  • the notification unit 20 notifies the user of this. Can be easily found at hand. Therefore, after returning the spool 2 to the connection position, the practitioner presses the plunger of the syringe at a slower speed than before, and injects the liquid medicine at the normal liquid injection speed.
  • FIGS. 3 and 4 show a second embodiment of the present invention, in which an upper seal portion 31 is provided at the upper end of the upper land 19 of the spool 2. , 31 is greater than the distance between the connecting position and the closing position of the spool 2. Thereby, the sliding area of the lower seal portion 24 on the inner surface of the spool hole 10 is protected from contamination by the outside air, and the risk of chemical liquid contamination is reduced.
  • FIGS. 5 to 7 show a third embodiment of the present invention, in which a setting mechanism (means) 33 for setting an external force at which the spool 2 starts sliding is provided, and is configured as follows. .
  • a circumferential projection 34 protruding outward in the radial direction is formed at an intermediate portion of the notification section 20 of the spool 2 in the axial center direction.
  • An adjusting cylinder 35 externally fitted to the upper part of the notification section 20 of the spool 2 is externally fitted and fixed to the upper end of the cylindrical section 7 of the housing 1.
  • the adjusting cylinder 35 is integrally formed of a material that can be elastically deformed, and a tapered screw portion 36 that is tapered upward is formed on an outer peripheral surface of a lower portion thereof. Also, in the axial center part of the inner peripheral surface of the adjustment cylinder 35, A circumferential projection 37 protruding radially inward is formed, and the circumferential projection 37 is disposed above the circumferential projection 34 of the spool 2.
  • a slit 45 penetrating in the radial direction is provided in a portion extending from the upper end of the adjusting cylinder 35 to the lower end of the peripheral projection 34.
  • the constituent material of the adjusting cylinder 35 the same material as that of the spool 2 is used.
  • the cover 5 is externally fitted to the adjusting cylinder, and the female screw portion 38 on the inner periphery thereof is screwed to the tapered screw portion 36. As shown in FIGS. 5 and 7, the adjustment of the cover 5 is performed. By the screw advance / retreat with respect to the cylinder 35, the slit 45 of the adjustment cylinder 35 expands and contracts in the circumferential direction, and the inner diameter of the peripheral projection 37 expands and contracts. It is to be noted that a normal screw portion that is not connected to the tapered screw portion 36 may be formed in the adjustment cylinder 35, and a tapered screw portion may be formed in the lid 5.
  • FIG. 8 and FIG. 9 show a fourth embodiment of the present invention, in which a housing 1 has a main body 4, an injection line mounting body 39, a lid 5, and the like.
  • the inflow port 12 is formed at the lower portion of the cylindrical portion 7, and as shown in Fig. 8, when the spool 2 is in the connection position, the force for communicating with the group 25 of the spool 2 as shown in Fig. 9 When the spool 2 is in the shut-off position, it communicates with the operating inlet 21.
  • the outflow port 13 is higher than the inflow port 12 and is always in communication with the group 25 of the spool 2.
  • An inlet-side operation port 40 located below the inflow port 12 is formed in the cylindrical portion 7 so as to penetrate in the left-right direction, and communicates the tip mounting portion 8 and the operation inflow portion 21.
  • the injection line mounting body 39 can be arranged at substantially the same position as the tip mounting portion 8 in the vertical direction, is fixed to the left side surface of the cylindrical portion 7, and has a vertical direction between them.
  • a communication channel 41 is formed, the communication channel 41 communicates with the outflow port 13, and a communication hole 42 communicating with the communication channel 41 and the inside of the injection line mounting body 39 is provided at the right end of the injection line mounting body 39. It is formed to penetrate in the left-right direction.
  • the length of the lower land 17 of the spool 2 in the axial direction is small.
  • a plurality of the seal portions 43 may be provided, but in order to increase the sealing performance, the spool portions are preferably single, and a projection 44 is formed on the lower end surface of the spool 2 to be in contact with the facing portion 11. When the spool 2 is in the connection position, most of the lower end surface of the spool 2 is separated from the facing portion 11.
  • the drug solution in the tip mounting section 8 firstly flows through the inlet-side operation port 40 through the operation inflow section 21. And the spool 2 starts sliding upward. Thereafter, the communication between the inflow port 12 and the group 25 of the spoonhole 2 is cut off, the inflow port 12 also communicates with the operating inflow section 21, and the chemical solution flows from the inflow port 12 into the operating inflow section 21. As a result, the spool 2 slides to the predetermined blocking position shown in FIG.
  • FIGS. 10 to 12 show a fifth embodiment of the present invention, in which the tip mounting section 8 and the injection line mounting section 9, the inflow port 12 and the outflow port 13 are arranged in the up-down direction (substantially). ) The same position.
  • longitudinal seal portions 46 in the axial direction are arranged at equal intervals in the circumferential direction between the upper and lower seal portions 23 and 22 of the lower land 17, and a plurality of partitions are provided between the upper and lower seal portions 23 and 22.
  • FIGS. 13 and 14 show a sixth embodiment of the present invention.
  • the housing 1 includes the main body 4, the injection line mounting body 39, the lid 5 and the like. However, only the differences will be described below.
  • the inflow port 12 is formed in the middle part of the cylindrical portion 7 in the vertical direction, and is always in communication with the groove 25 of the spool 2.
  • the outflow port 13 is formed on the lower side of the cylindrical portion 7 and is lower than the inflow port 12. As shown in FIG. 13, when the spool 2 is in the connection position, the group of the spool 2 Spool 2 shuts off as shown in Fig. 14 When in the position, it communicates with the actuation inlet 21.
  • An outlet-side operation port 49 located below the outflow port 13 is formed through the cylindrical portion 7 in the left-right direction, and communicates with the inflow portion 21 for operation.
  • a communication path 41 between the cylinder 7 and the injection line mounting body 39 communicates with the outflow port 13 and the outlet-side operation port 49.
  • a main part, that is, a part (or all) of the facing part 11 of the housing 1 except for an outer peripheral part is an auxiliary body 50 made of an elastic material such as rubber.
  • the drug solution in the injection line mounting body 39 firstly flows through the outlet side operation port 49 through the operation inflow section.
  • the auxiliary body 50 flows into the inside 21 and is elastically deformed downward by the pressure of the chemical solution.
  • the spool 2 slides upward due to the pressure of the chemical solution, so that the connection between the outflow port 13 and the group 25 is cut off, and the outflow port 13 communicates with the inflow section 21 for operation.
  • the spool 2 slides further upward, and the spool 2 comes to a predetermined blocking position shown in FIG.
  • FIGS. 15 and 16 show a seventh embodiment of the present invention, which is a modification of the first embodiment, and only the differences will be described below.
  • the tip mounting section 8 is slightly higher than the injection line mounting section 9.
  • the outflow port 13 is also used as an outlet-side operation port, and is formed at the lower end of the cylindrical portion 7 and is always in communication with the operation inflow portion 21.
  • a main portion that is, a portion (or all) of the opposing portion 11 of the housing 1 except for the outer peripheral portion is an auxiliary body 50 made of an elastic material such as rubber.
  • a projection 44 is formed on the lower end surface of the spool 2 so as to be in contact with the facing portion 11.
  • the chemical solution flowing from the inflow port 12 into the group 25 of the spool 2 is attached to the injection line via the flow path 26, the inflow section 21 for operation, and the outflow port 13. Flows into part 9.
  • the auxiliary body 50 is elastically deformed downward by the pressure of the chemical solution in the working inflow portion 21. Thereafter, the spool 2 slides upward due to the pressure of the chemical solution, and the communication between the inflow port 12 and the group 25 is cut off.
  • Figs. 13 and 14 the force of separately providing the outflow port and the outlet-side operation port is used as shown in Figs. 11, 15, and 16. May be.
  • Fig. 8 and Fig. 9 the inflow port and the inlet side operation port are provided separately.
  • Fig. 1 Fig. 7, Fig. 10, Fig. 11, Fig. 13-Fig.
  • the port can be shared.
  • FIG. 17 to FIG. 24 show an eighth embodiment of the present invention.
  • the chemical liquid supply control device has an operating means 3 in addition to the housing 1 and the spool 2. Although the main body 4 of the housing 1 is transparent, the lid 5 of the housing 1 may be transparent.
  • the position of the spool 2 can be freely changed between a connection position shown in FIG. 22 and a shut-off position shown in FIG.
  • the spool 2 includes a lower end portion 117, a lower land 118, an intermediate portion 119, an upper land 120, a stopper portion 121, a notification portion 122, and a shaft portion 123, which are directed upward in the above order. And is formed continuously (integrally formed).
  • the upper and lower lands 120 and 118 have the same diameter, and the other parts of the spool 2 have smaller diameters.
  • the lower end portion 117 and the lower end surface of the lower land 118 are opposed to the opposing portion 11 of the housing 1 in the up-down direction, and a space therebetween is defined as an operation inflow portion 124.
  • the chemical liquid supply stopping means is constituted by the operating port 14, the chemical liquid supply stopping means may include the operating inflow portion 124.
  • the seal portions on the outer periphery of the lower land 118 and the upper land 120 also have a function as setting means for determining the above-mentioned sliding start external force.
  • these seal portions are usually constituted by a seal member which is formed integrally with the lower land 118 and the upper land 120 and is a force.
  • a groove (circumferential groove) 125 is formed between the lower land 118 and the upper land 120, that is, the radially outer side of the intermediate portion 119, and the force that is always in communication with the inflow port 12 It communicates with port 13 only when spool 2 is in the connection position.
  • the upper surface of the stopper portion 121 contacts the lower end surface of the lid 5 when the spool 2 is at the blocking position.
  • the shaft portion 123 has a smaller diameter than the notification portion 122, and a ring portion 127 that protrudes radially outward in a curved shape is formed in the middle portion thereof over the entire circumference.
  • a circumferential groove 128 is formed between 127 and the notification unit 122.
  • the operating means 3 constitutes, together with the engaging means described later, a malfunction notifying means for notifying a malfunction relating to the supply of the medicinal solution from the medicinal solution supplying means to the injection line. This is separate from the malfunction notification means to be performed.
  • the operating means 3 includes a support 130, a lever 131, and a return spring 132.
  • the support 130 is formed integrally with the lid 5 of the housing 1, and a support 133 is erected on the support 130, and a pair of support shafts 134 project forward and backward from the support 133. Is established.
  • the lever 131 has its middle part in the longitudinal direction placed on the support part 133 and is engaged with the support shaft 134 so as to be able to freely engage and disengage via elastic deformation. It is pivoted.
  • the distal end of the lever 131 is formed as a bifurcated engagement portion 135, and the front and rear sides of the engagement portion 135 are engaged with the circumferential groove 128 of the spool so as to be freely detachable.
  • the engagement means for releasably engaging the operating means 3 with the spool is constituted by the portion 135 and the circumferential groove 128.
  • the set operation force is set to be larger than the external force at which the spool 2 starts sliding.
  • the return panel 132 is for returning the lever 131 after swinging to its original position.
  • the return panel 132 is integrally formed in a curved shape at the base of the lever 131, and is elastically interposed between the base of the lever 131 and the support 130. Thus, the base of the lever 131 is urged upward.
  • an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment section 9,
  • a tip of a syringe filled with a drug solution is mounted on the tip mounting section 8 as a drug solution supply means.
  • the spool 2 is at the connection position shown in FIG. 22, and the inflow port 12 and the outflow port 13 are connected by the group 125.
  • the plunger of the syringe Prior to injection, first, the plunger of the syringe is pressed, and the drug solution is injected into the flow path to the patient, that is, into the tip mounting portion 8, the spool hole 10, the injection line mounting portion 9, and the inside of the injection line. After filling and performing the so-called “priming” for removing the internal air, the injection needle of the injection line is punctured into the blood vessel of the patient. In addition, the case where the above priming is performed with a physiological saline is also used.
  • the base of the lever 131 is pushed down, and an upward operating force is applied to the spool 2.
  • the spool 2 slides upward, and the negative pressure generated due to this causes the chemical solution in the injection line to first move into the working inflow portion 124 through the working port 14. It flows into the working inlet 124 through the working port 14 and the outlet port 13.
  • the operator moves upward, whereby the practitioner can easily know that the blood vessel is not secured.
  • the base of the lever 131 tries to swing upward by the return panel 132, but the engaging portion 135 of the lever 131 comes into contact with the ring portion 127 of the spool 2 so as to come into contact. Therefore, the lever 131 does not return to the original position, and it can be visually confirmed from the position of the lever 131 that no blood vessel is secured.
  • the patient does not forcibly inject the medicinal solution into a non-necessary location, and the patient does not feel any significant pain.
  • the patient can smoothly receive the required medical treatment, and can prevent additional medical treatment such as treatment due to leakage of the drug solution out of the blood vessel. It is expected that the efficiency will also increase.
  • the normal injection pressure equal to or lower than the set injection pressure of the drug solution, that is, the normal pressure increase of the drug solution due to the gauge of the syringe needle, the cross-sectional area of the syringe, etc. during injection, for example, the syringe Due to an increase in the chemical pressure at the initial stage of sliding of the plunger and an increase in the chemical pressure due to the regular injection speed of the chemical, an upward external force acts on the lower end surface of the spool 2 through the outlet-side operation port 14. . However, since the external force at which the spool 2 starts to slide is larger than this external force, there is no fear that the spool 2 will slide unexpectedly.
  • the maximum injection rate of the liquid medicine is determined, but the liquid medicine is also injected at a speed higher than the normal injection speed as described below. There is nothing. That is, when the injection speed of the drug solution becomes faster than the normal injection speed, the drug solution in the injection line mounting portion 9 first flows into the working inflow portion 124 through the outlet-side working port 14, and the pressure of the drug solution is increased. Acts on the spool 2, and the upward external force acting on the spool 2 becomes equal to or greater than the external force at the start of sliding. As a result, as shown in FIG. 23, the spool 2 slides upward to be in the cut-off position, and the lever 131 swings, so that the injection of the medicinal solution cannot be performed.
  • the notifying unit 122 and the swinging lever 131 that project greatly upward from the lid inform the user of this, the practitioner must make sure that the injection speed of the drug solution is higher than the normal injection speed. Can be easily known at hand. Therefore, after returning the spool 2 to the connection position by pressing the lever 131 or the spool 2, the practitioner presses the syringe plunger at a lower speed than before, so that the injection speed of the drug solution becomes the normal injection speed. Then, a chemical solution may be injected.
  • FIG. 25 to FIG. 27 show a ninth embodiment of the present invention, in which the spool hole 10 of the housing 1 has a lower small-diameter portion 141 and an upper side where the diameter is larger than the small-diameter portion 141.
  • Consisting of a large diameter part 142 of The spool 2 has a lower end portion 117, a lower small-diameter land 143, a lower intermediate portion 144, an upper small-diameter land 145, an upper intermediate portion 146, a large-diameter land 147, a notification portion 122, and a shaft portion. 12 3 are connected in an upward direction in the above order.
  • the upper and lower lands 145 and 143 have the same diameter, and have a larger diameter than the lower end 117, the upper and lower intermediate portions 146 and 144, and the shaft 123, and the notification unit 122 has a larger diameter than these.
  • the large diameter land 147 is the largest diameter.
  • the upper and lower small lands 145, 143 are slidably provided in the small diameter portion 141, and the large lands 147 are slidably provided in the large diameter portion 142.
  • the distance between the upper small-diameter lands 145 is larger than the distance between the connection position and the blocking position of the spool 2.
  • the sliding area of the upper small-diameter land 145 on the inner surface of the spool hole 10 is protected from contamination by the outside air, and the possibility of contamination of the chemical solution is reduced.
  • the large-diameter land 147 is also used as the stopper portion of the first embodiment.
  • FIG. 28 shows a tenth embodiment of the present invention, in which a spool 2 is divided between an upper intermediate portion 146 and a large-diameter land 147, and is composed of a lower component 149 and an upper component 150. .
  • the negative pressure acting on the lower end surface of the lower component 149 is equal to the area ratio of both lower end surfaces ((the area of the lower end surface of the large diameter land 147) Z (the lower end portion 117 of the spool 2 and the lower small diameter). Large area multiplied by the area of the lower end surfaces of both the land 143) or (the maximum cross-sectional area of the large-diameter land 147) Z (the maximum cross-sectional area of the lower small-diameter land 143) ”.
  • the operating force for sliding the spool 2 upward is larger than in the case of the ninth embodiment, and the operator himself can operate the lever 131 more reliably than in the case of the ninth embodiment. I can recognize.
  • FIGS. 29-33 show an eleventh embodiment of the present invention.
  • the housing 1 is made of transparent plastic, and has first and second members 203 and 204 and a lid 205.
  • the first member 203 has a bottomed cylindrical shape that opens rearward in the axial direction (front-rear direction), and its distal end is in contact with the distal end of the spool 2.
  • An opposing portion 211 is formed, and the inside thereof is formed as a spool hole 210 in the axial direction.
  • An outflow port 213 is formed in a side wall portion on the tip end side of the first member 203 in a radial direction, and the port 213 communicates with the spool hole 210.
  • the second member 204 has a substantially cylindrical shape that opens in both axial directions, and has a connecting portion 214 on the base side and an injection line mounting portion 209 on the distal end side smaller in diameter than the connecting portion 214. And are integrally formed.
  • the connection portion 214 is externally fitted and fixed to the first member 203 from the distal end side, and the outflow port 213 is included in the connection portion 214, and the outflow port 213 is connected to the first and second members 203 and 204. It communicates with the injection line mounting part 209 via the gap 215.
  • the lid 205 restricts sliding of the spool 2 toward the rear side in the axial center direction.
  • the lid 205 is externally fitted and fixed to the base end of the first member 203, and has an opening at the center thereof.
  • the portion 217 is formed to penetrate in the up-down direction, and its inner peripheral portion projects radially inward from the first member 203.
  • the spool 2 is inserted into the spool hole 210 from the rear in the axial direction, and is slidably provided in the spool hole 210 in the axial direction.
  • the tip of the spool 2 contacts the opposing portion 211 of the first member 203.
  • the position can be freely changed between a contacting position (see FIGS. 29 and 31) and a blocking position (see FIGS. 30 and 33) described later.
  • the spoonlet 2 has a base portion 219 and a sealing member 222 provided at a distal end portion of the base portion 219.
  • An operation inflow portion 221 is provided between the distal end portion of the spool 2 and the facing portion 211 of the first member 203. I have.
  • the base portion 219 constitutes most of the spool 2, is substantially cylindrical, and has a through hole 224 formed in the axial direction.
  • the distal end of the through hole 224 is formed as a communication passage 225, and is formed as an operation port 226 which is always in communication with the distal end force inflow portion 221 of the communication passage 225.
  • a contact portion 229 projecting radially outward and located in front of the lid 205 in the axial direction is formed at an intermediate portion in the axial direction of the base portion 219. As shown in FIG.
  • the portion 229 is in a position force S in contact with the front surface of the lid 205, and is in a blocking position of the spool 2.
  • the base of the base part 219 is a tip mounting part 208, and is axially rearward from the lid 205. It protrudes greatly.
  • the tip mounting section 208 is provided with a flange 227 that is screwed with a luer adapter provided in the chemical liquid supply means.
  • a notification unit 220 is formed on the outer peripheral surface of the tip portion (or the tip portion and its vicinity) of the tip mounting portion.
  • the notification unit 220 is located inside the housing 1 when the spool 2 is at the connection position, and protrudes axially rearward from the housing 1 when the spool 2 is at the blocking position.
  • the sealing member 222 is externally fitted and fixed to the distal end portion of the base portion 219 via elastic deformation, and is housed in the spool hole 210.
  • the sealing member 222 and the distal end portion of the base portion 219 An inflow port 212 that communicates with the communication passage 225 and the spool hole 210 and that is connected to the outflow port 213 intermittently by sliding of the spool 2 is formed through the side wall in the radial direction.
  • first to fourth lands 241 to 244 are arranged in the axial direction from the distal end portion to the proximal end portion, and these outer peripheral portions serve as a seal portion.
  • the inner surface of the spool hole 210 is slidably (pressed) in the liquid-tight state (air-tight state) so as to be slidable in the axial direction.
  • the contact makes it possible to hold the spool 2 at an arbitrary sliding position, and an external force greater than the external force required for sliding the spool (sliding start external force, set external force) is applied.
  • the spool 2 is slidable. That is, the seal portion on the outer periphery of the lands 241 to 244 also has a function as a setting means for determining the external force for starting the sliding.
  • seal portions are usually formed integrally with the lands 241 to 244, but may be constituted by separate seal members.
  • the first and second lands 241 and 242 form a blocking group 245 that communicates with the outflow port 213 when the connection between the inflow port 212 and the outflow port 213 is cut off.
  • a connection group 246 is provided between the second and third lands 242, 243. The group 246 always communicates with the inflow port 212 and communicates with the outflow port 213 only when the inflow port 212 and the outflow port 213 are connected. Further, the distance between the third and fourth lands 243, 244 is larger than the distance between the connection position of the spool 2 and the blocking position.
  • the distal end surface of the base portion 219 has a tapered surface 247 which is slightly tapered toward the rear in the axial center direction so that the communication passage 225 and the inflow portion 221 for operation can communicate well. Being done. Then, the communication passage 225 or the through-hole 224 and the communication passage 225 Although a liquid supply stopping means is configured, the chemical liquid supply stopping means may include an inflow portion 221 for operation.
  • an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment portion 209.
  • a tip of a syringe filled with a drug solution is mounted on the tip mounting section 208 as a drug solution supply means.
  • the spool 2 is at the connection position shown in FIGS. 29 and 31, and the inflow port 212 and the outflow port 213 are connected by the connection gnoreve 36.
  • the plunger of the syringe is depressed so that the flow path to the patient, that is, the through hole 224, the working inflow portion 221, the inflow port 212, the connection group 246, and the outflow port 2 13.
  • the injection line mounting part 209 and the inside of the injection line with a drug solution to remove the air inside the so-called "priming"
  • the injection needle is punctured into the patient's blood vessel.
  • the priming may be performed using a physiological saline solution.
  • the plunger of the syringe is pressed.
  • the blood vessel is secured, that is, the injection needle of the injection line is punctured into the blood vessel, and the injection line is connected to the blood vessel.
  • the spool 2 is held at the connection position as described below, so that the drug solution flows into the blood vessel and the injection can be performed as usual.
  • the pressure of the medicinal solution acts from the communication passage 225 into the inflow portion 221 for operation, so that the normal injecting pressure equal to or lower than the set injecting pressure of the medicinal solution, that is, the gauge of the needle of the syringe at the time of injection,
  • the normal pressure increase of the chemical due to the cross-sectional area of the syringe, etc. for example, the pressure increase of the chemical at the initial stage of sliding of the plunger of the syringe, and the pressure increase of the chemical due to the regular injection speed of the chemical, etc.
  • An external force acts axially rearward on the surface. However, since the external force at which the spool 2 starts sliding is larger than this external force, there is no danger of the spool 2 sliding unexpectedly. As described above, injection can be performed as usual.
  • a large abnormal injection pressure equal to or higher than the set injection pressure of the liquid acts on the distal end surface of the spool 2 via the communication passage 225 and the inflow portion 221 for operation, and the external force acting on the spool 2 in the axial rearward direction is slid. It becomes more than the external force at the start of movement.
  • the spool 2 slides rearward in the axial direction, and continues to flow into the working inflow portion 221 via the chemical liquid communication passage 225 of the syringe.
  • the spool 2 comes to the blocking position shown in FIGS. 30 and 33, the contact portion 229 contacts the lid 205, the outflow port 213 communicates with the blocking group 245, and the outflow port 213 flows out of the inflow port 212.
  • the connection of the port 213 is interrupted, and the notification unit 220 projects from the housing 1 rearward in the axial center.
  • the plunger of the syringe cannot be pressed, and the drug solution is not forcibly injected into a portion that is not a necessary portion, so that the patient may not feel significant pain.
  • the patient can smoothly receive the required medical treatment, and can prevent additional medical treatment such as treatment due to leakage of the drug solution out of the blood vessel. It is expected that it can be improved.
  • the practitioner can easily know the above-mentioned abnormality, that is, that the blood vessel is not secured, at the hand side. Since the notification unit 220 protrudes from the housing 1, the practitioner can easily visually recognize the notification unit, and also can easily know at hand that the blood vessel is not secured.
  • the drug solution in the tip mounting portion 208 and the like can be returned into the syringe.
  • the drug solution can be prevented from being wasted, thereby preventing an increase in medical costs. it can.
  • the pressure of the chemical in the inflow portion 221 for operation may decrease, and the spool 2 may return to the connection position. By pressing the spool forward in the axial direction to return the spool 2 to the connection position.
  • the drug solution in the operation inflow portion 221 can be returned to the syringe again.
  • a syringe for administering a drug solution must In the case of a syringe filled with a drug solution (prefilled syringe) that often cannot pull the plunger, or in the case of administering a drug solution via a catheter inserted deep into the patient, or When administering radiopharmaceuticals, even if the syringe and injection line are covered with a protective wall to prevent exposure to the practitioner, even if the drug solution leaks out of the blood vessels, there is Can be performed.
  • the chemical solution is injected at a speed higher than the normal injection speed. There is nothing. That is, if the injection speed of the drug solution becomes faster than the normal injection speed after the initial stage of the injection, as described above, a large abnormal injection pressure equal to or higher than the set injection pressure of the drug solution is generated by the communication passage 225 and the inflow portion 221 for operation.
  • the external force acting on the distal end surface of the spool 2 through the shaft 2 and acting on the spool 2 in the axially rearward direction is equal to or greater than the external force at the start of sliding.
  • the spool 2 is brought into the shut-off position, and it becomes impossible to inject the medicinal solution. Therefore, a large burden is not applied to the patient, and the notifying unit 220 informs the user of this. Can be easily found at hand. Therefore, after returning the spool 2 to the connection position, the practitioner presses the plunger of the syringe at a lower speed than before, and injects the medicinal solution at the normal injecting speed of the medicinal solution.
  • FIG. 34 shows a twelfth embodiment of the present invention, which is provided with a setting mechanism (means) 233 for setting a value of an external force necessary for sliding of the spool 2, and is configured as follows.
  • a peripheral projection 234 having a larger diameter than the base of the base portion 219 is formed at the tip of the tip mounting portion 208 of the spool 2.
  • the base end of the first member 203 of the housing 1 is provided with an adjusting cylinder externally fitted to the base 219.
  • Adjusting cylinder 235 is externally fitted and fixed. Adjusting cylinder 235 is integrally formed of elastically deformable material A tapered single thread portion 236 tapered upward is formed on the outer peripheral surface of the distal end portion. A circumferential projection 237 that is located axially rearward of the first member 203 and protrudes inward in the radial direction is formed integrally with a halfway portion of the inner circumferential surface of the adjusting cylinder 235 in the axial direction. 237 is disposed axially rearward of the circumferential projection 234 of the spool 2. Further, a slit (not shown) penetrating in the radial direction is provided in a portion extending from the base end of the adjusting cylinder 235 to the peripheral projection 234. As the constituent material of the adjusting cylinder 235, the same material as that of the spool 2 is used.
  • the cover 205 is externally fitted to the adjusting cylinder 235, and the female screw portion 238 on the inner periphery thereof is screwed to the tapered screw portion 236.
  • the slits 235 expand and contract in the circumferential direction, and the inner diameter of the circumferential projection 237 expands and contracts.
  • the outer diameter of the peripheral projection 234 is set to be larger than this inner diameter.
  • the outer diameter of the contact portion 229 of the base portion 219 is made larger than the inner diameter, so that the circumferential projection 237 serves as a stopper of the contact portion 229.
  • the adjusting cylinder 235 may be formed with a normal screw portion that does not use the taper screw portion 236, and the lid 205 may be formed with a tapered screw portion.
  • the peripheral protrusion 237 of the adjusting cylinder 235 and / or the peripheral protrusion 234 of the spool 2 are elastically deformed, and the periphery of the spool 2 is deformed.
  • the projection 234 needs to pass through the inside of the peripheral projection 237 of the adjustment cylinder 235. Therefore, by expanding and contracting the inner diameter of the circumferential projection 237 of the adjusting cylinder 235, the external force required for the circumferential projection 234 of the spool 2 to pass through the inside of the circumferential projection 237 of the adjusting cylinder 235, that is, the external force at which the sliding starts, is automatically increased. Can be set for any reason.
  • FIG. 35 to FIG. 38 show a thirteenth embodiment of the present invention, in which the connecting portion 214 of the second member 204 of the housing 1 is fitted over the entire first member 203. Further, the distal end of the base part 219 is fitted into the base of the sealing member 222 of the spool 2 via elastic deformation and integrated, and a through hole 224 is formed in the base part 219 and the sealing member 222. ing.
  • the return operation of the spool from the shut-off position to the connection position is performed by manually operating the spool or by pulling the plunger of the syringe with the force S and the return.
  • various panels such as a coil panel and a compressed air panel for pressing the spool forward in the axial direction, or other return means may be provided.
  • the drug solution administration set includes a syringe filled with a drug solution as a drug solution supply means and the drug solution supply control device according to the present invention.
  • the syringe is connected to the chemical liquid supply control device by screwing the luer lock adapter provided on the syringe with the flange of the tip mounting part of the chemical liquid supply control device; ) Connecting the injection line between the syringe and the drug supply control device and connecting the injection needle to the injection line mounting part of the drug solution supply control device; and (3) connecting the drug solution control device and the injection needle May be connected to an injection line.
  • a drug solution is supplied to a drug solution supply means and a drug solution supply control device, and further into a catheter, an injection needle, an indwelling needle, a three-way cock (a three-way cock function), an extension tube, and other blood vessels of a living body.
  • a drug solution supply means and a drug solution supply control device for controlling the drug concentration of a drug solution.
  • the drug solution supply control method according to the present invention the drug solution supply control device used in the method, and the drug solution administration set using the device are provided as a method, a device, and a set for administering a drug solution to a patient. Useful.

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Abstract

A chemical liquid supply control device capable of easily detecting whether a blood vessel is secured or not when a chemical liquid is dosed, comprising (a) a housing (1) installed between a chemical liquid supply means and an injection line, (b) a spool (2) installed in the housing (1) slidably in the axial direction and connecting the chemical liquid supply means to the injection line so as to be disconnected and connected by the slidable movement thereof in the axial direction, and (c) a trouble alarm means alarming troubles on a chemical liquid supply stop means stopping the supply of the chemical liquid from the chemical liquid supply means to the injection line and/or the supply of the chemical liquid from the chemical liquid supply means to the injection line. When the injection line is closed, the device operates the chemical liquid supply stop means and/or the trouble alarm means.

Description

明 細 書  Specification
薬液供給制御方法、その方法に使用する薬液供給制御装置及びその装 置を用いた薬液投与セット  Chemical solution supply control method, chemical solution supply control device used in the method, and chemical solution administration set using the device
技術分野  Technical field
[0001] 本発明は、薬液供給制御方法、その方法に使用する薬液供給制御装置及びその 装置を用いた薬液投与セットに関する。  The present invention relates to a drug solution supply control method, a drug solution supply control device used in the method, and a drug solution administration set using the device.
背景技術  Background art
[0002] シリンジにより、患者に薬液を投与する方法には、シリンジのチップに接続可能な注 射針、既に血管に留置された留置針、或いは、カテーテル力 延びる所謂注射ライ ン等にシリンジを接続する方法がある。この際、予め、血管が確保、即ち、注射ライン に接続された注射針の先端が血管内に確実に留置されてレ、る場合は問題なレ、。  [0002] A method of administering a drug solution to a patient by using a syringe includes connecting an injection needle that can be connected to a syringe tip, an indwelling needle already indwelled in a blood vessel, or a so-called injection line that extends a catheter force. There is a way to do that. At this time, there is a problem if a blood vessel is previously secured, that is, if the tip of the injection needle connected to the injection line is securely placed in the blood vessel.
[0003] しかし、そうでなレ、場合には、血管までの流路及び接続された注射針の先端の位 置を確認する必要がある。通常、最初に、薬液又は生理食塩水等により、患者までの 注射ライン内の空気を除去する所謂「プライミング」を行った後、注射ラインの注射針 を患者の血管に穿刺する。その後、シリンジのプランジャーを引いて、注射ラインに血 液が逆流してくる所謂「フラッシュバック」を目視し、注射針が血管内に確実に留置さ れていることを確認する。  [0003] However, if this is not the case, it is necessary to confirm the flow path to the blood vessel and the position of the tip of the connected injection needle. Usually, first, so-called "priming" is performed to remove air in the injection line to the patient with a drug solution or a physiological saline solution, and then the injection needle of the injection line is punctured into a blood vessel of the patient. After that, pull out the plunger of the syringe and observe the so-called “flashback” in which blood flows back to the injection line, and confirm that the injection needle is securely placed in the blood vessel.
[0004] CTスキャナーや MRIスキャナー（磁気共鳴診断装置）等の装置の内部にいる患者 に薬液を投与する場合には、その必要性から、肘静脈等に対し、手動により、又は、 注入手段として自動注入機を使用して、高速の注入速度で投与することも少なくない 。患者に薬液を上記のように投与する際には、例えば、予め、血管が確保されている 場合でも、装置内にいる患者が動くことで、注射針の先端が患者の血管から外れるこ と力 Sある。そのため、薬液の投与前にフラッシュバックを行レ、、血管が確保されている か否かを確認する必要がある。  [0004] When administering a drug solution to a patient inside a device such as a CT scanner or an MRI scanner (magnetic resonance diagnostic device), it is necessary to manually or inject the drug into the elbow vein or the like due to its necessity. It is not uncommon to use automatic injection machines to administer dosing at high injection rates. When a drug solution is administered to a patient as described above, for example, even if a blood vessel has been previously secured, the movement of the patient in the device causes the tip of the injection needle to be disengaged from the patient's blood vessel. There is S. Therefore, it is necessary to perform a flashback before administering the drug solution to confirm whether or not blood vessels are secured.
[0005] 通常、医療機関では、血管内へ注射すべき薬液が血管外へ漏出することを防ぐた め、薬液を投与する直前に、再度、シリンジのプランジャーを引き、注射ラインへの血 液の逆流を確認している。し力 ながら、高速の注入速度による注射針先端の位置 の移動や、患者の体動などにより、留置された注射針の先端位置が血管内に正しく 留置されないことがあるという問題があった。 [0005] Normally, in a medical institution, in order to prevent a drug solution to be injected into a blood vessel from leaking out of a blood vessel, immediately before administering the drug solution, the plunger of the syringe is pulled again and the blood solution to the injection line is drawn. The backflow has been confirmed. Position of the needle tip due to the high injection speed There is a problem that the tip position of the placed needle may not be properly placed in the blood vessel due to movement of the patient or body movement of the patient.
又、同時に患者が CTスキャナーや MRIスキャナ一等の内部にいる場合、血液の 逆流を確認しづらいとレ、う問題もあった。  At the same time, if the patient is inside a CT scanner, MRI scanner, or the like, there is a problem that it is difficult to confirm the backflow of blood.
[0006] この際、血管が正しく確保されていない場合には、薬液が必要でない部位、即ち、 血管外に無理に注入されることによって、患者は著しい痛みを感じることになる。又、 これにより、無理に注射された薬剤が無駄になると共に、当初予定していた検查を再 度行う必要が生じるばかりか、患者における、無理に薬液が注入された部位等への 治療も行わなければならなレ、。これらのことは必要でない医療行為とコストの負担を 招く要因にもなり得る。 [0006] At this time, if the blood vessels are not properly secured, the patient will feel remarkable pain by forcibly injecting the drug solution into a site that is not required, that is, outside the blood vessels. In addition to this, the forcibly injected drug is wasted, and not only does the initially scheduled test need to be performed again, but also the treatment of the patient in the site where the drug solution was forcibly injected is performed. You have to do it. These can also lead to unnecessary medical practices and costs.
[0007] 更に、薬液の投与を行うシリンジが、予め薬液が充填された薬液充填済みシリンジ（ プレフィルドシリンジ）の場合には、ガスケットがシリンジバレルの開放端近傍に位置し ていたり、高圧蒸気滅菌時のガスケット抜け防止の目的で、開放端からストッパーが 挿着されている場合がある力 これらの場合には、構造上、プランジャーを引くことが できない。そのため、上記のものでは、血管の確保の確認が行えず、従って、血管が 確保されていないことに起因する上記の問題が必然的に発生する可能性があつたの が実情である。  [0007] Further, when the syringe for administering the drug solution is a syringe filled with the drug solution (a prefilled syringe) filled with the drug solution in advance, the gasket may be located near the open end of the syringe barrel, or may be subjected to high-pressure steam sterilization. The stopper may be inserted from the open end to prevent the gasket from coming off. In these cases, the plunger cannot be pulled due to the structure. For this reason, in the above, it is not possible to confirm the securing of blood vessels, and therefore, the above-mentioned problem caused by the lack of blood vessels may inevitably occur.
[0008] 又、薬液の投与をカテーテルを介して行う場合にも、カテーテルの挿入部位によつ ては、換言すれば、カテーテルが患者の体内の奥深い部位に挿入されている場合に も、上記同様の問題が生じていた。  [0008] In addition, even when the drug solution is administered via a catheter, depending on the insertion site of the catheter, in other words, even when the catheter is inserted into a deep site inside the patient, A similar problem had arisen.
[0009] 更に、薬液の種類によっては、その最大注入速度が定められているものもあるが、 従来においては、薬液の注入速度が正規注入速度よりも大である場合に、これを施 術者に報知したり、或いは、薬液の注入を停止したりすることができない場合が少なく なぐそのため、上記の場合には、患者に負担が掛かっていたのが実情である。  [0009] Furthermore, the maximum infusion rate is determined for some types of drug solutions, but conventionally, when the injection speed of the drug solution is higher than the normal injection speed, the operator is required to set the maximum injection speed. In many cases, it is not possible to notify the patient or to stop the injection of the drug solution. Therefore, in the above case, the patient is burdened.
[0010] 又、放射線医薬品を投与する際には、施術者の被爆を防止するために、シリンジや 注射ラインも防護壁で覆われている場合があるが、そのような場合には、血液の逆流 を視覚的に確認できなレ、。そのため、上記の場合には、血管の確保の確認が行えず 、従って、血管が確保されていないことに起因する上記の問題が必然的に発生する 可能性があつたのが実情である。 [0010] In addition, when administering a radiopharmaceutical, a syringe or an injection line may be covered with a protective wall in order to prevent the practitioner from being exposed to radiation. The reflux cannot be visually confirmed. For this reason, in the above case, it is not possible to confirm the securing of the blood vessel, and therefore, the above-described problem caused by the lack of the blood vessel necessarily occurs. The possibility is the fact.
発明の開示  Disclosure of the invention
発明が解決しょうとする課題  Problems the invention is trying to solve
[0011] 解決しょうとする問題点は、「薬液の投与を行なう患者が CTスキャナーや MRIスキ ャナ一等の内部にいる場合」や、「薬液の投与を行うシリンジがプレフィルドシリンジで ある場合」や、「患者の体内の奥深い部位に挿入されているカテーテルを介して、薬 液の投与を行なう場合」や、「放射線医薬品を投与する際に、施術者の被曝を防止 するために、シリンジや注射ラインも防護壁で覆われている場合」には、血管が確保 されてレ、るカ 否かを容易に検出できなかった点等である。 [0011] The problem to be solved is that "the patient who administers the drug solution is inside a CT scanner or an MRI scanner," or "the syringe that administers the drug solution is a prefilled syringe." Or `` when administering a drug solution via a catheter inserted deep inside the patient's body '' or `` when administering radiopharmaceuticals, a syringe or In the case where the injection line is also covered with a protective wall, ”it means that it was not possible to easily detect whether blood vessels were secured or not.
課題を解決するための手段  Means for solving the problem
[0012] 本発明は、上記問題点を解決した薬液供給制御方法、その方法に使用する薬液 供給制御装置及びその装置を用いた薬液投与セットを提供することを目的とし、本発 明の薬液供給制御方法の特徴とするところは、 (a) 薬液供給手段と注射ライン間に 介装されたハウジングと、 (b) ノ、ウジング内に軸心方向に摺動自在に備えられて、 軸心方向の摺動により、薬液供給手段と注射ラインを断続自在に接続するスプール と、（c) 薬液供給手段から注射ラインへの薬液の供給を停止させる薬液供給停止 手段及び/又は薬液供給手段から注射ラインへの薬液供給に関する不具合を報知 する不具合報知手段を使用し、注射ラインが閉鎖状態の場合に、薬液供給停止手 段及び/又は不具合報知手段を作動させる点にある。 An object of the present invention is to provide a chemical solution supply control method that solves the above problems, a chemical solution supply control device used in the method, and a chemical solution administration set using the device. The features of the control method are as follows: ( a ) a housing interposed between the chemical solution supply means and the injection line; and (b) a slidably provided in the axial direction in the housing and the housing. (C) a chemical liquid supply stopping means for stopping the supply of the chemical liquid from the chemical liquid supply means to the injection line and / or an injection line from the chemical liquid supply means. The problem is to use a malfunction notification means for notifying a malfunction related to the supply of the drug solution to the system, and to activate the drug solution stop means and / or the malfunction notification means when the injection line is closed.
尚、ハウジングに、スプールの軸心方向一端面と対向し、この端面との間が作動用 流入部とされる対向部が形成されており、薬液の圧力が設定圧力以上の場合に、薬 液供給停止手段が、薬液供給手段又は注射ラインの薬液を作動用流入部に供給し て、スプールを軸心方向に摺動させ、これにより、薬液供給手段から注射ラインへの 薬液の供給を停止させることもある。  The housing is provided with an opposing portion which is opposed to one end surface in the axial direction of the spool, and which is defined as an inflow portion for operation between the end surface and the end surface. The supply stopping means supplies the liquid medicine from the liquid supply means or the injection line to the inflow portion for operation, and slides the spool in the axial direction, thereby stopping the supply of the liquid medicine from the liquid supply means to the injection line. Sometimes.
又、スプールに係脱自在に係合された操作手段を使用し、注射ラインに液体を満 たした状態で、操作手段によりスプールに軸心方向の操作力を作用させ、これにより 、注射ラインが開放状態の場合には、スプールが摺動して、注射ライン内の液体がハ ウジング内に吸引され、注射ラインが閉鎖状態の場合には、スプールが摺動せず、ス プールと操作手段の係合が解除されることもある。 Also, using the operating means detachably engaged with the spool, the operating means applies an operating force in the axial direction to the spool while the injection line is filled with the liquid. When the injection line is open, the spool slides and liquid in the injection line is sucked into the housing. When the injection line is closed, the spool does not slide and the spool does not slide. The engagement between the pool and the operating means may be released.
更に、注射ラインが開放状態の場合に、注射ライン内の液体が、スプールにおける 、操作方向とは反対側の端面とハウジング間に吸引されることもある。  Further, when the injection line is open, the liquid in the injection line may be sucked between the end face of the spool, which is opposite to the operation direction, and the housing.
本発明の薬液供給制御装置の特徴とするところは、 (a) 薬液供給手段と注射ライ ン間に介装されたハウジングと、 (b) ハウジング内に軸心方向に摺動自在に備えら れ、軸心方向の摺動により、薬液供給手段と注射ラインを断続自在に接続するスプ ールと、（c) 薬液供給停止手段及び/又は不具合報知手段を有し、薬液供給停止 手段は、注射ラインが閉鎖状態の場合及び Z又は薬液の圧力が設定圧力以上の場 合に薬液供給手段から注射ラインへの薬液の供給を停止させる手段とされ、不具合 報知手段は、薬液供給手段から注射ラインへの薬液供給に関する不具合を報知す る手段とされた点にある。  The chemical liquid supply control device according to the present invention is characterized by (a) a housing interposed between the chemical liquid supply means and the injection line, and (b) a slidably provided in the housing in the axial direction. And a spool for intermittently connecting the chemical liquid supply means and the injection line by sliding in the axial direction, and (c) a chemical liquid supply stop means and / or a malfunction notification means. When the line is closed and when the pressure of Z or the drug solution is higher than the set pressure, it is a means to stop the supply of the drug solution from the drug solution supply means to the injection line, and the malfunction notification means is from the drug solution supply means to the injection line. In other words, it is a means of reporting a problem with the supply of a chemical solution.
尚、ハウジングに、スプールの軸心方向一端面と対向し、この端面との間が作動用 流入部とされる対向部が形成され、薬液供給停止手段が、作動時に、薬液供給手段 又は注射ラインの薬液を作動用流入部に供給して、スプールを軸心方向に摺動させ ることちある。  The housing is provided with an opposing portion facing the one end surface in the axial direction of the spool, and an opposing portion between the end surface and the end surface is defined as an operation inflow portion. Is supplied to the inflow portion for operation, and the spool is slid in the axial direction.
又、ハウジングに、 (a) スプール孔と、 (b) 薬液供給手段からの薬液をスプール 孔内に流入させる流入ポートと、（c) スプール孔内の薬液を注射ラインに流出させ る流出ポートが形成され、スプール孔内に、流入ポートと流出ポートを断続自在に接 続するスプールが軸心方向に摺動自在に備えられ、流入ポートと流出ポートの接続 時において、薬液の圧力が上昇した際に、この圧力により、スプールを摺動させて、 流入ポートと流出ポートの接続を遮断する薬液供給停止手段が備えられることもある 更に、スプールが、軸心方向に離間した一対のランドを有し、両ランド間が、流入ポ ートと流出ポートを接続するグループとされ、薬液供給停止手段が、スプールに形成 されて、グノレーブと作動用流入部を連通させる流路とされることもある。  Also, the housing has (a) a spool hole, (b) an inflow port through which the chemical solution from the chemical solution supply means flows into the spool hole, and (c) an outflow port through which the chemical solution in the spool hole flows out to the injection line. A spool is formed in the spool hole to connect the inflow port and the outflow port intermittently so as to be slidable in the axial direction, and when the pressure of the chemical solution rises when the inflow port and the outflow port are connected. The pressure may be provided with a chemical liquid supply stopping means for sliding the spool to cut off the connection between the inflow port and the outflow port.Furthermore, the spool has a pair of lands separated in the axial direction. The group between the lands may be a group connecting the inflow port and the outflow port, and the chemical solution supply stopping means may be formed in the spool to be a flow path for communicating the gnoreve and the operating inflow section. That.
又、薬液供給停止手段が、ハウジングに形成されて、薬液供給手段と作動用流入 部を連通させる入口側作動ポートとされることもある。  In some cases, the chemical liquid supply stopping means is formed in the housing and serves as an inlet-side operation port for communicating the chemical liquid supply means with the inflow portion for operation.
更に、流入ポートが、入口側作動ポートと兼用とされることもある。 又、薬液供給停止手段が、ハウジングに形成されて、注射ラインと作動用流入部を 連通させる出口側作動ポートとされることもある。 Further, the inflow port may be used also as the inlet-side operation port. In some cases, the chemical liquid supply stopping means is formed in the housing and serves as an outlet-side operation port for communicating the injection line with the inflow portion for operation.
更に、流出ポートが、出口側作動ポートと兼用とされることもある。  Further, the outflow port may be used also as the outlet-side operation port.
又、対向部の少なくとも一部が、弾性材料からなる補助部とされることもある。  Further, at least a part of the facing portion may be an auxiliary portion made of an elastic material.
更に、薬液の圧力が設定圧力以上になった際にのみ、スプールの摺動を許容して Furthermore, only when the pressure of the chemical solution exceeds the set pressure, the sliding of the spool is allowed.
、薬液供給手段と注射ラインの接続を遮断する設定手段が備えられることもある。 又、設定手段の設定圧力が調整可能とされることもある。 In some cases, setting means for interrupting the connection between the drug solution supply means and the injection line may be provided. The setting pressure of the setting means may be adjustable.
更に、スプールの操作手段を有し、ハウジングが、（a) スプールが軸心方向に摺 動自在に内装されたスプール孔と、 (b) 薬液供給手段からの薬液をスプール孔内 に流入させる流入ポートと、 (c) スプールの摺動により、流入ポートと断続自在に接 続されて、スプール孔内の薬液を注射ラインに流出させる流出ポートと、 (d) 注射ラ インの薬液を作動用流入部に流入させる作動ポートを有し、スプールと操作手段間 に、両者を係脱自在に係合し、スプールを対向部から離間する方向に操作した際に おいて、操作手段の操作力が設定操作力以上になった場合に、上記係合を解除す る係合手段が備えられることもある。  Furthermore, the housing has a spool operating means, and the housing has (a) a spool hole in which the spool is slidably provided in the axial direction, and (b) an inflow through which the chemical from the chemical solution supply means flows into the spool hole. A port, (c) an outflow port that is connected to the inflow port intermittently by sliding the spool, and allows the drug solution in the spool hole to flow out to the injection line, and (d) a drug solution in the injection line for operation. It has an operation port that flows into the spool, and the two are detachably engaged between the spool and the operating means, and the operating force of the operating means is set when the spool is operated in the direction away from the facing part. An engagement means for releasing the engagement when the operating force is exceeded may be provided.
又、スプールが、軸心方向に離間し且つスプール孔内に軸心方向に摺動自在に 備えられる一対のランドを有し、両ランド間が、流入ポートと流出ポートを接続するグ ノレーブとされることちある。  Further, the spool has a pair of lands which are spaced apart in the axial direction and are slidably provided in the spool direction in the axial direction, and between the lands is a gnorebe for connecting the inflow port and the outflow port. There are things.
更に、スプールが、 （a) 軸心方向に離間して、スプール孔内に軸心方向に摺動自 在に備えられた一対の小径ランドと、 (b) 両小径ランドとスプールの軸心方向他端 面間に配設されると共に、小径ランドよりも大径とされて、スプール孔内に軸心方向に 摺動自在に備えられる大径ランドを有することもある。  Further, the spool is: (a) a pair of small-diameter lands provided in the spool hole so as to be slid in the axial direction by being spaced apart in the axial direction; and (b) the axial direction of the two small-diameter lands and the spool. There may be a large-diameter land provided between the other end surfaces and having a larger diameter than the small-diameter land and slidably provided in the axial direction in the spool hole.
又、両小径ランドと大径ランドが別体とされることもある。  In addition, both small-diameter lands and large-diameter lands may be provided separately.
更に、スプールに、薬液供給手段と注射ラインの接続の遮断時に、ハウジングの外 部に突出して、上記遮断を報知する報知部が備えられることもある。  Further, the spool may be provided with a notifying unit that projects to the outside of the housing and notifies the shut-off when the connection between the chemical solution supply unit and the injection line is cut off.
又、操作手段が、 （a) ハウジングに揺動自在に枢支された梃子と、（b) 揺動後の 梃子を原位置に復帰させる復帰パネを有し、係合手段が、（i) スプールに形成され た周溝と、（ii)梃子に形成され、周溝に弾性変形を介して係脱自在に係合する係合 咅を有することもある。 The operating means includes (a) a lever pivotally supported by the housing and (b) a return panel for returning the lever after swinging to the original position, and the engaging means comprises (i) A circumferential groove formed in the spool, and (ii) an engaging groove formed in the lever and engaged with the circumferential groove so as to be removably engaged through elastic deformation. 有 す る may be present.
更に、梃子が、流入ポートと流出ポートの接続の遮断時に、この遮断を報知する報 知部とされることちある。  Further, when the connection between the inflow port and the outflow port is cut off, the lever may be used as a notification unit for notifying the cutoff.
又、ハウジングに、流出ポートを囲繞する筒状の注射ライン装着部が備えられ、注 射ライン装着部に、注射ラインと接続されるルアーロックアダプターが備えられることも ある。  Further, the housing may be provided with a cylindrical injection line mounting portion surrounding the outflow port, and the injection line mounting portion may be provided with a luer lock adapter connected to the injection line.
更に、ハウジングが、（a) 軸心方向に形成され、内部にスプールが軸心方向に摺 動自在に備えられるスプール孔と、 (b) ノ、ウジングの側部に形成され、スプール孔と 連通すると共に、注射ラインと接続される流出ポートを有し、スプールが、（i) 薬液供 給手段と接続されると共に、作動用流入部と連通する連通路と、（ii)スプールの側部 に形成され、連通路及びスプール孔と連通すると共に、スプールの摺動により、流出 ポートと断続自在に接続される流入ポートを有することもある。  Further, a housing is formed in (a) an axial direction in which a spool is slidably provided in an axial direction, and (b) a spool hole is formed in a side portion of a housing and a housing, and communicates with the spool hole. And an outflow port connected to the injection line, wherein the spool is connected to (i) a chemical liquid supply means and communicates with an inflow portion for operation; and (ii) a side portion of the spool. It may have an inflow port which is formed and communicates with the communication passage and the spool hole, and is connected to the outflow port intermittently by sliding the spool.
又、ハウジング力 (a) 略筒状とされ、内部がスプール孔とされて、先端部が対向 部とされると共に、側壁部に流入ポートが半径方向に形成された第 1部材と、 (b) 軸 心方向両方に開口する略筒状とされ、基部側の接続部と、注射ラインと接続される先 端部側の注射ライン装着部を有する第 2部材を有し、接続部が第 1部材に先端側か ら外嵌固着されて、流入ポートが接続部に内有されると共に、流入ポートが、第 1 ·第 2部材の間隙を介して、注射ライン装着部と連通することもある。 (A) a first member having a substantially cylindrical shape, a spool hole inside, a front end portion facing, and an inflow port formed in a side wall portion in a radial direction; ) It has a substantially cylindrical shape that opens in both axial directions, and has a second member having a connection portion on the base side and an injection line mounting portion on the front end connected to the injection line, and the connection portion is the first member. The inflow port is fixed to the member from the distal end side, and the inflow port is internally provided in the connection portion, and the inflow port may communicate with the injection line mounting portion via the gap between the first and second members. .
更に、注射ライン装着部に、注射ラインと接続されるルアーロックアダプターが備え られることちある。  Further, a luer lock adapter connected to the injection line may be provided at the injection line mounting part.
又、ハウジングが、第 1部材の基端部に備えられ、スプールの軸心方向後方側への 摺動を規制する蓋体を有することもある。  Further, the housing may be provided at a base end portion of the first member, and may have a lid for restricting sliding of the spool in the axial rearward direction.
更に、スプールの外周部に、第 1一第 3ランドが、先端部から基端部に向かって、軸 心方向に並設され、第 1 ·第 2ランド間が、流入ポートと流出ポートの接続の遮断時に 、流出ポートと連通する遮断用グループとされ、第 2 ·第 3ランド間が、流入ポートと、 常時、連通すると共に、流入ポートと流出ポートの接続時に、流出ポートと連通する 接続用グノレーブとされることもある。  Further, the first and third lands are arranged in the axial direction on the outer peripheral portion of the spool from the distal end portion to the proximal end portion, and a connection between the inflow port and the outflow port is provided between the first and second lands. The connection between the 2nd and 3rd lands is always in communication with the inflow port, and when the inflow port is connected to the outflow port, the connection between the 2nd and 3rd lands. Sometimes referred to as gnoreve.
又、スプールの外周部における、第 3ランドよりも基部側に、第 4ランドが備えられ、 第 3 ·第 4ランド間の距離が、スプールの接続位置と遮断位置間の距離よりも大とされ ることちある。 In addition, a fourth land is provided on the outer peripheral portion of the spool on a base side with respect to the third land, The distance between the third and fourth lands may be larger than the distance between the connection position and the blocking position of the spool.
更に、スプールに貫通孔が軸心方向に形成されて、スプールの基部が、シリンジの チップが分離可能に装着されるチップ装着部とされると共に、貫通孔の先端部が連 通路とされることちある。  Furthermore, a through hole is formed in the spool in the axial direction, the base of the spool is a tip mounting portion on which the tip of the syringe is separably mounted, and the tip of the through hole is a communication passage. There.
又、スプールの摺動に必要な外力の値を設定する設定手段が備えられることもある 更に、設定手段の設定値が調整可能とされることもある。  Further, setting means for setting a value of an external force necessary for sliding of the spool may be provided. Further, a setting value of the setting means may be adjustable.
又、スプールに、流入ポートと流出ポートの接続の遮断時に、ハウジングの軸心方 向後方に突出して、上記遮断を報知する報知部が備えられることもある。  Further, the spool may be provided with a notifying portion that projects rearward in the axial direction of the housing when the connection between the inflow port and the outflow port is cut off, and notifies the above shutoff.
更に、薬液供給手段と流入ポートとの間に、三方活栓機能が備えられることもある。 本発明の薬液投与セットの特徴とするところは、薬液供給制御装置と薬液供給手 段を有する点にある。  Further, a three-way stopcock function may be provided between the chemical solution supply means and the inflow port. A feature of the medical solution administration set of the present invention is that it has a chemical solution supply control device and a chemical solution supply means.
尚、薬液供給手段が注射用シリンジであることもある。  Incidentally, the drug solution supply means may be a syringe for injection.
又、注射用シリンジが薬液充填済みシリンジであることもある。  The syringe for injection may be a syringe filled with a drug solution.
更に、薬液供給手段が点滴用バッグであることもある。  Further, the chemical solution supply means may be a drip bag.
尚、点滴用バッグが薬液充填済みバッグであることもある。  The infusion bag may be a bag filled with a chemical solution.
又、薬液供給手段により供給される薬液が造影剤であることもある。  Also, the chemical supplied by the chemical supply means may be a contrast agent.
更に、造影剤が MRI造影剤であることもある。  Further, the contrast agent may be an MRI contrast agent.
発明の効果 The invention's effect
以上詳述したように、本発明によれば、「薬液の投与を行なう患者が CTスキャナー や MRIスキャナ一等の内部にいる場合」や、「薬液の投与を行うシリンジがプレフィル ドシリンジである場合」や、「患者の体内の奥深い部位に揷入されているカテーテル を介して、薬液の投与を行なう場合」や、「放射線医薬品を投与する際に、施術者の 被曝を防止するために、シリンジや注射ラインも防護壁で覆われている場合」におい て、血管が確保されていない場合には、これを容易に検出できて、薬液の血管外漏 出を防止できると共に、患者にとっても、血管外漏出という不安から開放されるメリット がある。 又、薬液の投与直前に、シリンジのプランジャーを引く必要がないので、スムーズ且 つ効率的な医療行為を実現できる。 As described in detail above, according to the present invention, "when a patient who administers a drug solution is inside a CT scanner, an MRI scanner, or the like" or "when a syringe that administers a drug solution is a prefilled syringe" Or `` when administering a drug solution via a catheter inserted deep into the body of a patient '' or `` when administering radiopharmaceuticals, a syringe or In the case where the injection line is also covered with a protective wall '', if blood vessels are not secured, this can be easily detected and the leakage of the drug solution to the blood vessel can be prevented, and the patient can be treated extravascularly. There is a merit to be released from the fear of leakage. Further, since there is no need to pull the plunger of the syringe immediately before administration of the medicinal solution, a smooth and efficient medical operation can be realized.
請求項 2、 4記載の発明によれば、薬液の注入速度が設定された正規注入速度より も速くなつて、薬液の圧力が設定圧力以上になった場合には、薬液を注入できなくな つて、上記状態での薬液の注入を防止でき、患者に大きな負担が掛かることがない。 又、上記異常を手元側で容易に知ることができると共に、この異常を視覚的に確認す る必要もない。  According to the inventions set forth in claims 2 and 4, when the injection speed of the chemical solution is higher than the set regular injection speed and the pressure of the chemical solution becomes higher than the set pressure, the chemical solution cannot be injected. In addition, the injection of the medicinal solution in the above-mentioned state can be prevented, and a large burden is not applied to the patient. In addition, the above abnormality can be easily known at hand, and there is no need to visually confirm the abnormality.
請求項 11記載の発明によれば、弾性材料から成る補助部により、スプールが遮断 位置に摺動することを補助できる。  According to the eleventh aspect, the auxiliary portion made of the elastic material can assist the spool to slide to the blocking position.
請求項 12及び請求項 31記載の発明によれば、流入ポートと流出ポートの接続を 遮断する際の薬液の圧力を設定できる。  According to the twelfth and thirty-first aspects of the invention, it is possible to set the pressure of the chemical solution when disconnecting the connection between the inflow port and the outflow port.
請求項 13及び請求項 32記載の発明によれば、流入ポートと流出ポートの接続を 遮断する際の薬液の圧力を自由に設定できる。  According to the thirteenth and thirty-second aspects of the invention, it is possible to freely set the pressure of the chemical solution when disconnecting the connection between the inflow port and the outflow port.
請求項 18記載の発明によれば、スプールを摺動させるための操作力が大となるの で、施術者は、操作機構を操作していることをより確実に認識できる。  According to the invention of claim 18, since the operating force for sliding the spool is large, the practitioner can more surely recognize that the operating mechanism is being operated.
請求項 19記載の発明によれば、スプールを摺動させるための操作力がより大とな るので、施術者は、操作機構を操作していることを更により確実に認識できる。  According to the nineteenth aspect, the operating force for sliding the spool is increased, so that the practitioner can more reliably recognize that the operating mechanism is being operated.
請求項 20、請求項 21及び請求項 33記載の発明によれば、施術者が報知部又は 梃子を視認することで、流入ポートと流出ポートの接続が遮断されたことを容易に知 ること力 Sできる。  According to the invention described in claims 20, 21 and 33, the operator can easily recognize that the connection between the inflow port and the outflow port has been interrupted by visually recognizing the notification section or lever. S can.
図面の簡単な説明 BRIEF DESCRIPTION OF THE FIGURES
[図 1]本発明の第 1実施例を示す断面図である。 FIG. 1 is a sectional view showing a first embodiment of the present invention.
[図 2]図 1の作動状態図である。 FIG. 2 is an operation state diagram of FIG. 1.
[図 3]本発明の第 2実施例を示す断面図である。 FIG. 3 is a sectional view showing a second embodiment of the present invention.
[図 4]図 3の作動状態図である。 FIG. 4 is an operation state diagram of FIG. 3.
[図 5]本発明の第 3実施例を示す断面図である。 FIG. 5 is a sectional view showing a third embodiment of the present invention.
[図 6]図 5のスプールの作動状態図である。 FIG. 6 is an operation state diagram of the spool in FIG. 5.
[図 7]図 5の設定機構の作動状態図である。 [図 8]本発明の第 4実施例を示す断面図である。 FIG. 7 is an operation state diagram of the setting mechanism of FIG. 5. FIG. 8 is a sectional view showing a fourth embodiment of the present invention.
[図 9]図 8の作動状態図である。  FIG. 9 is an operation state diagram of FIG.
園 10]本発明の第 5実施例を示す断面図である。 FIG. 10 is a sectional view showing a fifth embodiment of the present invention.
[図 11]図 10の作動状態図である。  FIG. 11 is an operation state diagram of FIG.
[図 12]図 10の A-A線矢視断面図である。  FIG. 12 is a sectional view taken along line AA of FIG. 10.
園 13]本発明の第 6実施例を示す断面図である。 FIG. 13 is a sectional view showing a sixth embodiment of the present invention.
園 14]図 13の作動状態図である。 FIG. 14 is an operation state diagram of FIG.
園 15]本発明の第 7実施例を示す断面図である。 FIG. 15 is a sectional view showing a seventh embodiment of the present invention.
[図 16]図 15の作動状態図である。  FIG. 16 is an operation state diagram of FIG.
園 17]本発明の第 8実施例を示す正面図である。 FIG. 17 is a front view showing an eighth embodiment of the present invention.
[図 18]図 17の平面図である。  FIG. 18 is a plan view of FIG.
[図 19]図 17の底面図である。  FIG. 19 is a bottom view of FIG. 17.
[図 20]図 17の左側面図である。  FIG. 20 is a left side view of FIG. 17.
園 21]図 17の右側面図である。 Garden 21] is a right side view of FIG.
園 22]図 17の正面断面図である。 Garden 22] is a front sectional view of FIG.
園 23]図 22の作動状態図である。 FIG. 23 is an operation state diagram of FIG.
園 24]図 22の作動状態図である。 Garden 24] is an operation state diagram of FIG. 22.
[図 25]本発明の第 9実施例を示す正面断面図である。 園 26]図 25の作動状態図である。  FIG. 25 is a front sectional view showing a ninth embodiment of the present invention. FIG. 26 is an operation state diagram of FIG.
園 27]図 25の作動状態図である。 Garden 27] is an operation state diagram of FIG. 25.
園 28]本発明の第 10実施例を示す正面断面図である。 園 29]本発明の第 11実施例を示す側面図である。 FIG. 28 is a front sectional view showing a tenth embodiment of the present invention. FIG. 29 is a side view showing an eleventh embodiment of the present invention.
[図 30]図 29の作動状態図である。  FIG. 30 is an operational state diagram of FIG. 29.
[図 31]図 29の B— B線矢視断面図である。  FIG. 31 is a sectional view taken along line BB of FIG. 29.
[図 32]図 31の C—C線矢視断面図である。  FIG. 32 is a sectional view taken along line CC of FIG. 31.
[図 33]図 30の D-D線矢視断面図である。  FIG. 33 is a sectional view taken along the line DD in FIG. 30.
[図 34]本発明の第 12実施例を示す縦側断面図である。  FIG. 34 is a longitudinal sectional view showing a twelfth embodiment of the present invention.
[図 35]本発明の第 13実施例を示す側面図である。 園 36]図 35の作動状態図である。 FIG. 35 is a side view showing a thirteenth embodiment of the present invention. FIG. 36 is an operating state diagram of FIG.
[図 37]図 35の E— E線矢視断面図である FIG. 37 is a sectional view taken along line E—E in FIG. 35.
[図 38]図 36の F-F線矢視断面図である, 符号の説明 FIG. 38 is a sectional view taken along line F-F of FIG. 36, description of reference numerals
1 ハウジング  1 Housing
2 スプール  2 spool
3 操作手段  3 Operation means
10, 210 スプール孔  10, 210 Spool hole
11 , 211 対向部  11, 211 Opposing part
12, 212 流入ポート  12, 212 Inflow port
13, 213 流出ポート  13, 213 Outflow port
19, 17 上側'下側ランド  19, 17 Upper side 'lower side land
20, 122, 220 報知部  20, 122, 220 Notification Department
21 , 124， 221 作動用流入部  21, 124, 221 Inlet for operation
25 グノレーブ  25 Gunolave
26 流路  26 channels
33 設定機構  33 Setting mechanism
40 入口側作動ポート  40 Inlet operation port
49 出口側作動ポート  49 Outlet side operation port
50 補助体  50 auxiliary
120, 118,上側'下側ランド  120, 118, upper 'lower land
122 報知部  122 Information Department
125 グノレーブ  125 Gunolave
128 周溝  128 circumferential groove
131 梃子  131 lever
132 復帰用パネ  132 Return Panel
145, 143 上側'下側小径ランド  145, 143 Upper side 下 Lower side small land
147 大径ランド 150, 149 上側 ·下側構成体 147 Large diameter land 150, 149 Upper and lower components
203, 204 第 1 ·第 2部材  203, 204 1st and 2nd members
205 蓋体  205 lid
208 チップ装着部  208 Chip mounting part
209 注射ライン装着部  209 Injection line mounting part
214 接続部  214 connection
215 間隙  215 gap
225 連通路  225 connecting passage
233 設定機構  233 Setting mechanism
241、一 244 第 1一第 4ランド  241, 1 244 1st-4th land
245 遮断用グループ  245 Blocking group
246 接続用グループ  246 connection group
発明を実施するための最良の形態  BEST MODE FOR CARRYING OUT THE INVENTION
[0016] 本発明は、血管が確保されているカ 否かを容易に検出でき、薬液の血管外漏出 を防止できる薬液供給制御方法、その方法に使用する薬液供給制御装置及びその 装置を用いた薬液投与セットを提供する。  [0016] The present invention provides a chemical supply control method capable of easily detecting whether or not a blood vessel is secured and preventing leakage of a chemical outside a blood vessel, a chemical supply control device used in the method, and a device using the chemical supply control device. A drug solution administration set is provided.
実施例 1  Example 1
[0017] 以下、本発明の第 1実施例を、図 1及び図 2の図面に基づき説明すると、薬液供給 制御装置は、薬液供給手段 (薬液供給ライン）（図示省略)と注射ライン (図示省略） 間に介装されるもので、ハウジング 1と、スプール (ガスケット） 2等を有する。  Hereinafter, a first embodiment of the present invention will be described with reference to FIGS. 1 and 2. The chemical liquid supply control device includes a chemical liquid supply unit (chemical liquid supply line) (not shown) and an injection line (not shown). It is interposed between and has a housing 1, a spool (gasket) 2, and the like.
[0018] 薬液供給手段とは、薬液を生体の血管内に投与するための医療器具を意味し、注 射用シリンジ、点滴用バック、点滴用ボトル等を挙げることができるが、これらに限定さ れるものではない。薬液供給手段には、薬液が既に充填されている、薬液充填済み シリンジ (プレフィルドシリンジ）、薬液充填済みバック、薬液充填済み点滴用ボトル等 も含まれる。  [0018] The drug solution supply means means a medical device for administering a drug solution into a blood vessel of a living body, and examples thereof include an injection syringe, an infusion bag, and an infusion bottle. It is not something to be done. The drug solution supply means includes a drug solution-filled syringe (prefilled syringe), a drug solution-filled bag, a drug solution-filled drip bottle, and the like, which are already filled with the drug solution.
[0019] 本明細書において薬液とは、皮膚等を通して生体の血管内に直接適用される、溶 液、懸濁液、乳濁液等であって、各種疾病の治療又は診断に用いる薬剤液、栄養剤 液、生理食塩水その他の医療用溶液を意味するが、これらに限定されるものではな レ、。尚、各種疾病の診断に用いる薬剤液としては、 MRI造影剤、エックス線造影剤、 超音波造影剤等の造影剤や各種診断薬を挙げることができる。 [0019] In the present specification, the drug solution is a solution, suspension, emulsion, or the like that is directly applied into the blood vessel of a living body through the skin or the like, and is a drug solution used for treatment or diagnosis of various diseases. Nutrient solution, saline or other medical solution, but not limited to Les ,. Examples of the drug solution used for diagnosis of various diseases include contrast agents such as MRI contrast agents, X-ray contrast agents, and ultrasound contrast agents, and various diagnostic agents.
[0020] 注射ラインとしては、シリンジのチップに装着可能な注射針、既に血管に留置され た留置針、或いは、カテーテル力 延びるライン等が使用される。尚、上記「注射」に は、長時間、大量（100ml以上）の薬液を投与する所謂「輸液」も含まれる。  [0020] As the injection line, an injection needle that can be attached to a syringe tip, an indwelling needle already indwelled in a blood vessel, a line that extends the force of a catheter, or the like is used. The term “injection” also includes so-called “infusion” in which a large amount (100 ml or more) of a drug solution is administered for a long time.
[0021] ハウジング 1はプラスチック製とされ、本体 4と蓋体 5を有する。  The housing 1 is made of plastic and has a main body 4 and a lid 5.
[0022] 本体 4は、上下方向に配設され且つ上方に開口する筒状（中空状)の筒部 (筒状部 ) 7と、筒部 7の上下方向中途部から右側方に、後述する流入ポート 12を囲繞するよ うに突設された筒状（中空状)のチップ装着部 8と、筒部 7の上下方向中途部から左 側方に、後述する流出ポート 13を囲繞するように突設された筒状（中空状)の注射ラ イン装着部 9を、一体形成して成る。尚、チップ装着部 8と注射ライン装着部 9は、平 面的に見た場合に、必ずしも同一直線上に並んでいる必要はなぐ筒部 7の周方向 に角度を設けて設置してもよレ、。  [0022] The main body 4 is provided with a tubular (hollow) tubular portion (tubular portion) 7 which is disposed in the up-down direction and opens upward, and which will be described later on the right side from the middle part of the tubular portion 7 in the up-down direction. A cylindrical (hollow) chip mounting portion 8 protruding so as to surround the inflow port 12 and a left side from a vertical middle portion of the cylindrical portion 7 so as to surround an outflow port 13 described later. The provided cylindrical (hollow) injection line mounting portion 9 is integrally formed. Note that the tip mounting section 8 and the injection line mounting section 9 need not necessarily be aligned on the same straight line when viewed in plan, and may be installed at an angle in the circumferential direction of the cylindrical section 7. Les ,.
[0023] 筒部 7の内部は、上下方向の軸心を有し且つ上方に開口するスプール孔 10とされ 、筒部 7の底部が、スプール 2の下端面と対向する対向部 11とされている。  The inside of the tubular portion 7 is a spool hole 10 having a vertical axis and opening upward, and the bottom of the tubular portion 7 is a facing portion 11 facing the lower end surface of the spool 2. I have.
[0024] チップ装着部 8は、その内部に、シリンジ（図示省略）のチップが分離可能に装着さ れると共に、三方活栓機能 (三方活栓)を有するもので、右端で開口すると共に、筒 部 7に左右方向（横方向）に貫通形成された流入ポート 12により、スプール孔 10と連 通している。流入ポート 12は、薬液供給手段からの薬液を、チップ装着部 8を介して 、スプール孔 10内に流入させる。チップ装着部 8に三方活栓機能を備える方法として 、チップ装着部 8に 2種以上の薬液の流路を任意に変更可能な三方活栓（図示しな レ、)を揷着する方法と、チップ装着部 8自体を三方活栓とする方法とがある。  The tip mounting part 8 has a syringe (not shown) detachably mounted therein and has a three-way stopcock function (three-way stopcock). The tip mounting part 8 opens at the right end and has a cylindrical part 7. An inflow port 12 penetrated in the left-right direction (lateral direction) communicates with the spool hole 10. The inflow port 12 allows the chemical from the chemical supply means to flow into the spool hole 10 via the tip mounting portion 8. As a method of providing the three-way cock function to the tip mounting part 8, a method of attaching a three-way cock (not shown) that can arbitrarily change the flow path of two or more kinds of chemicals to the tip mounting part 8 and a method of mounting the tip There is a method in which the part 8 itself is a three-way cock.
[0025] ここで、チップ装着部 8に三方活栓機能を備える理由は、下記の通りである。即ち、 薬剤が無事血管内に投与された場合でも (殆どの場合は何の問題もなく血管内に投 与される）、薬剤に対して血圧の低下など重篤なアレルギー反応が起こる場合があり 、このような場合には、迅速な対応が必要となる。この場合において、本発明のように 、三方活栓機能により血管が確保されていれば、ステロイド等の様々な薬剤の投与 による緊急治療を速やかに行うことが可能となる。 [0026] 上記のアレルギー反応は薬液注入中に起こることもあり、又、投与後暫くして起こる こともあるため、三方活栓機能を使用して検査を行う事が望ましいと考えられている。 又、投与ラインに残存する薬液のフラッシュとしての役割は、投与する薬液量が少 ない場合、適切な投与量を確保するという観点から重要となる。 Here, the reason why the tip mounting section 8 is provided with the three-way cock function is as follows. That is, even if the drug is successfully administered intravascularly (in most cases, it is administered without problems), serious allergic reactions such as a decrease in blood pressure may occur with the drug. In such a case, a quick response is required. In this case, if blood vessels are secured by the three-way cock function as in the present invention, it becomes possible to quickly perform emergency treatment by administration of various drugs such as steroids. [0026] The above allergic reaction may occur during the infusion of the drug solution, or may occur shortly after administration, so it is considered that it is desirable to perform the test using the three-way cock function. In addition, the role of the drug solution remaining on the administration line as a flush is important from the viewpoint of securing an appropriate dose when the amount of the drug solution to be administered is small.
[0027] チップ装着部 8には、薬液供給手段に備えられたルアーロックアダプター（ルアー口 ック機構）の雌螺子と螺合し得るよう、フランジを設けることが望ましい。又、薬液供給 手段における、チップ装着部 8との接続部には、チップ或いはチップに相当する部分 を有していることが望ましい。更に、薬液供給手段とチップ装着部 8間には、チップ或 いはチップに相当する部分を有してレ、るカテーテル等を装着してもよレ、。  It is desirable to provide a flange on the chip mounting portion 8 so that it can be screwed with a female screw of a luer lock adapter (luer lock mechanism) provided in the chemical solution supply means. Further, it is desirable that the connecting portion of the chemical liquid supply means with the chip mounting portion 8 has a chip or a portion corresponding to the chip. Further, a tip or a portion corresponding to the tip may be provided between the chemical solution supply means and the tip mounting portion 8 to mount a catheter or the like.
[0028] 注射ライン装着部 9は、注射ライン（図示省略）が分離可能に装着されるもので、チ ップ装着部 8よりも下位に配設されて、左端で開口すると共に、筒部 7に左右方向 (横 方向）に貫通形成された流出ポート 13により、スプール孔 10と連通している。流出ポ ート 13は、スプール孔 10内の薬液を注射ライン装着部 9に流出させるもので、流入 ポート 12よりも下位に配設されている。又、注射ライン装着部 9には、例えばノレアーロ ックアダプターのようなロック機構を設け、薬液の注入圧力が高い場合に、注射ライン と注射ライン装着部 9が不慮に外れないようにすることが好ましい。注射ライン装着部 9には、具体的には、カテーテル、注射針、留置針等が接続される。  [0028] The injection line mounting section 9 is provided with an injection line (not shown) detachably mounted, is disposed below the tip mounting section 8, is opened at the left end, and has a cylindrical section 7. An outlet port 13 penetrated in the left-right direction (lateral direction) communicates with the spool hole 10. The outflow port 13 allows the drug solution in the spool hole 10 to flow out to the injection line mounting section 9, and is disposed below the inflow port 12. Further, it is preferable that a lock mechanism such as a Nore lock adapter is provided in the injection line mounting portion 9 so that the injection line and the injection line mounting portion 9 do not accidentally come off when the injection pressure of the drug solution is high. Specifically, a catheter, an injection needle, an indwelling needle, and the like are connected to the injection line mounting section 9.
[0029] 蓋体 5は筒部 7の上端部に外嵌、固着されて、筒部 7の上端開口を施蓋しているが 、その中央部には、開口部 15が上下方向に貫通形成されている。  [0029] The lid 5 is externally fitted to and fixed to the upper end of the cylindrical portion 7, and covers the upper end opening of the cylindrical portion 7. An opening 15 is formed at the center of the lid so as to penetrate vertically. Have been.
[0030] スプール 2はスプール孔 10内に上下方向（軸心方向）に摺動自在に備えられて、 図 1に示すように、スプール 2の下端面がハウジング 1の対向部 11に当接し且つ流入 ポート 12と流出ポート 13を接続する接続位置と、図 2に示すように、接続位置よりも 上位とされ且つ上記接続を遮断する遮断位置とに位置変更自在とされ、蓋体 5の開 口部 15に揷通されている。スプール 2の構成材料としては、プラスチック、熱可塑性 エラストマ一、シリコンエラストマ一、ブチルゴム等が用いられる力 医療器具として使 用実績のある弾性部材であれば特に限定されない。  The spool 2 is slidably provided in the spool hole 10 in the vertical direction (axial direction). As shown in FIG. 1, the lower end surface of the spool 2 comes into contact with the facing portion 11 of the housing 1 and As shown in FIG. 2, the connection position for connecting the inflow port 12 and the outflow port 13 and, as shown in FIG. 2, a position higher than the connection position and a blocking position for blocking the connection can be freely changed. It is communicated to part 15. The constituent material of the spool 2 is not particularly limited as long as it is an elastic member that has been used as a power medical device using plastic, thermoplastic elastomer, silicon elastomer, butyl rubber, or the like.
[0031] スプール 2は、下側ランド 17と、下側ランド 17よりも小径とされた小径部 18と、下側 ランド 17と（略）同径とされた上側ランド 19と、両ランド 17, 19よりも小径とされた報知 部 20を、上記の順で、上方に向かって連設（一体形成）することで、構成されている。 尚、小径部 18を、各ランド 17, 19と同径としてもよレ、。 The spool 2 includes a lower land 17, a small-diameter portion 18 having a diameter smaller than that of the lower land 17, an upper land 19 having substantially the same diameter as the lower land 17, and both lands 17. Notice that the diameter was smaller than 19 The part 20 is configured by being connected upward (integrally formed) in the above order. The small diameter portion 18 may have the same diameter as the lands 17 and 19.
[0032] 下側ランド 17の下端面はハウジング 1の対向部 11と上下方向に関して対向し、両 者間が作動用流入部 21とされている力 スプール 2が接続位置にある時には、スプ ール 2の下端面は対向部 11と当接している。  [0032] The lower end surface of the lower land 17 is opposed to the opposing portion 11 of the housing 1 in the up-down direction, and when the force spool 2 having the actuation inflow portion 21 between the two is in the connection position, the spool is in the connected position. The lower end surface of 2 is in contact with the facing portion 11.
[0033] 下側ランド 17の外周部の上下端部と、上側ランド 19の下端部には、スプール孔 10 の内面に当接 (圧接）して、液漏れを防止するシール部 22 24が備えられている。 尚、上記当接により、スプール 2は任意の摺動位置で保持可能とされており、摺動開 始外力（設定外力）以上の大きさの外力がスプール 2に上下方向に作用した際に、ス プール 2が摺動可能とされている。即ち、シール部 22 24は、上記摺動開始外力を 定める設定手段としての機能も有してレ、る。  The upper and lower ends of the outer periphery of the lower land 17 and the lower end of the upper land 19 are provided with seal portions 2224 that abut (press) against the inner surface of the spool hole 10 to prevent liquid leakage. Have been. By the contact, the spool 2 can be held at an arbitrary sliding position. When an external force greater than the external force at the start of sliding (set external force) acts on the spool 2 in the vertical direction, Spool 2 is slidable. That is, the seal portion 2224 also has a function as a setting means for determining the above-mentioned external force at which the sliding starts.
[0034] シール部 22 24は、通常、スプール 2と一体形成される力 別体とされたシール部 材により構成される場合もある。そして、スプール 2が遮断位置にある時に、下側ラン ド 17の上下シール部 23, 22間に、流出ポート 13が位置するようにされている。  [0034] The seal portion 2224 may be usually formed of a seal member which is formed integrally with the spool 2 and is formed as a force. The outflow port 13 is located between the upper and lower seal portions 23 and 22 of the lower land 17 when the spool 2 is at the shut-off position.
[0035] 軸心方向に関して離間した両ランド 17, 19間、即ち、小径部 18の径方向外方側は 、グノレーブ（周溝） 25とされ、流入ポート 12とは、常時、連通しているが、流出ポート 1 3とは、スプール 2が接続位置にある時のみ、連通している。  [0035] A gnoreve (circumferential groove) 25 is formed between the lands 17 and 19 separated from each other in the axial direction, that is, the radially outer side of the small-diameter portion 18, and is always in communication with the inflow port 12. However, it communicates with the outflow port 13 only when the spool 2 is in the connection position.
[0036] 小径部 18の下部及び下側ランド 17には、薬液供給停止手段 (遮断手段）が構成さ れている。この手段は、流入ポート 12と流出ポート 13の接続時において、薬液の圧 力が設定圧力（異常圧力）以上になった際に、薬液の圧力により、スプール 2を摺動 させて、流入ポート 12と流出ポート 13の接続を遮断して、薬液の供給を停止するも ので、具体的には、バイパスとされる流路 26により構成されている。尚、薬液供給停 止手段には、作動用流入部 21も含めることがある。  [0036] The lower part of the small diameter portion 18 and the lower land 17 are provided with a chemical liquid supply stopping means (blocking means). This means, when the inflow port 12 and the outflow port 13 are connected to each other, when the pressure of the chemical solution exceeds the set pressure (abnormal pressure), the spool 2 is slid by the pressure of the chemical solution, and the inflow port 12 Since the supply of the chemical solution is stopped by disconnecting the connection between the outlet port 13 and the outlet port 13, it is specifically constituted by a flow path 26 which is a bypass. Note that the chemical liquid supply stopping means may include the inflow section 21 for operation.
[0037] 流路 26は、グループ 25と作動用流入部 21を連通させるもので、縦孔 27と横孔 28 力、ら成る。縦孔 27は、下側ランド 17及び小径部 18の下部の軸心部に形成されて、 下端で下方に開口している。横孔 28は、小径部 18の下部に前後方向に形成されて 、前後方向中央部が縦孔 27の上端部と連通すると共に、前後両端が前後方向に開 口してレ、る。尚、横孔 28の前後両端の一方のみが開口していてもよい。 [0038] 尚、上記薬液供給停止手段の作用により、薬液の設定注入圧力以下の通常注入 圧力、即ち、注射時における、シリンジの針のゲージ、シリンジの断面積等に起因す る薬液の通常の圧力上昇、例えば、シリンジのプランジャーの摺動初期における薬 液の圧力上昇、薬液の正規注入速度等による薬液の圧力上昇によって、スプール 2 に対して、上方向の外力が作用するが、この外力よりも、スプール 2の摺動開始外力 は大とされてレ、る。又、注射時に、血管が確保されていない場合と、薬液の注入速度 が正規注入速度以上の場合には、スプール 2に対して、薬液の設定注入圧力以上 の大きな異常注入圧力が、上方向の外力として、作用するが、この外力よりは、スプ ール 2の摺動開始外力は小さくされている。即ち、摺動開始外力は、注射時にスプー ノレ 2に作用する通常外力よりは大とされて、スプール 2が不慮に摺動しないようにされ ているが、注射時にスプール 2に作用する異常外力よりは小とされている。 The flow path 26 connects the group 25 and the inflow section 21 for operation, and includes a vertical hole 27 and a horizontal hole 28. The vertical hole 27 is formed in the lower center portion of the lower land 17 and the lower axial portion of the small-diameter portion 18 and opens downward at the lower end. The horizontal hole 28 is formed in the lower part of the small diameter portion 18 in the front-rear direction. The center part in the front-rear direction communicates with the upper end of the vertical hole 27, and both front and rear ends are opened in the front-rear direction. Note that only one of the front and rear ends of the horizontal hole 28 may be open. [0038] By the action of the above-mentioned drug solution supply stopping means, the normal injection pressure equal to or lower than the set injection pressure of the drug solution, that is, the normal injection pressure of the drug solution due to the gauge of the syringe needle, the cross-sectional area of the syringe, etc. at the time of injection. An upward external force acts on the spool 2 due to an increase in pressure, for example, an increase in the pressure of the chemical solution at the initial stage of sliding of the plunger of the syringe, or an increase in the pressure of the chemical solution due to a normal injection speed of the chemical solution. The external force at the start of sliding of the spool 2 is larger than that of the spool 2. In addition, when blood vessels are not secured at the time of injection and when the injection speed of the drug solution is higher than the normal injection speed, a large abnormal injection pressure higher than the set injection pressure of the drug solution is applied to the spool 2 in the upward direction. It acts as an external force, but the external force at which the spool 2 starts sliding is smaller than this external force. That is, the sliding start external force is set to be larger than the normal external force acting on the spoonle 2 at the time of injection so that the spool 2 does not slide unexpectedly. Is considered small.
[0039] 上側ランド 19の上面は、スプール 2が遮断位置にある時に、蓋体 5の下端面と当接 する。  [0039] The upper surface of the upper land 19 contacts the lower end surface of the lid 5 when the spool 2 is at the blocking position.
[0040] 報知部 20は、薬液供給手段から注射ラインへの薬液供給に関する不具合を報知 する不具合報知手段を構成するもので、薬液供給停止手段の作動時に、この作動を 報知する。報知部 20は、スプール 2が接続位置にある時には、ハウジング 1から若干 上方に突出し (突出させないこともある。）、スプール 2が遮断位置にある時には、ハウ ジング 1から大きく上方に突出する。尚、報知部 20の視認を確実なものとするために 、通常、報知部 20は着色される。更に、スプール 2の摺動又はそれに伴う報知部 20 の作動を電気的、光学的若しくは音響的信号に変えて報知させることもできる。電気 的、光学的若しくは音響的信号に変えて報知する手段としては、ベル、電球、発光ダ ィオード、ブザー、音を発する板などが挙げられる。  [0040] The notification unit 20 constitutes a failure notification unit that reports a failure related to the supply of the chemical solution from the chemical solution supply unit to the injection line. When the chemical solution supply stop unit operates, the notification unit 20 reports this operation. The notification unit 20 protrudes slightly upward from the housing 1 when the spool 2 is at the connection position (it may not be protruded), and largely protrudes from the housing 1 when the spool 2 is at the shut-off position. Note that the notification unit 20 is usually colored to ensure the visual recognition of the notification unit 20. Further, the sliding of the spool 2 or the operation of the notification section 20 accompanying the sliding can be changed into an electric, optical or acoustic signal to be notified. Means for notifying by changing to an electric, optical or acoustic signal include a bell, a light bulb, a light emitting diode, a buzzer, a sound emitting plate, and the like.
[0041] 上記構成例では、注射時には、注射ライン装着部 9に、シリンジのチップに装着可 能な注射針、既に血管に留置された留置針、或いは、カテーテル力 延びる注射ラ インが装着され、一方、チップ装着部 8に、薬液供給手段として、薬液が充填された シリンジのチップが装着される。又、スプール 2は図 1に示す接続位置にあって、その グループ 25により、流入ポート 12と流出ポート 13が接続されている。  In the above configuration example, at the time of injection, an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment portion 9. On the other hand, a tip of a syringe filled with a drug solution is mounted on the tip mounting section 8 as a drug solution supply means. The spool 2 is at the connection position shown in FIG. 1, and the inflow port 12 and the outflow port 13 are connected by the group 25.
[0042] 注射前には、まず、シリンジのプランジャーを押圧して、患者までの流路、即ち、チ ップ装着部 8、スプール孔 10、注射ライン装着部 9及び注射ライン内部に薬液を充填 して、上記内部の空気を除去する所謂「プライミング」を行なった後、注射ラインの注 射針を患者の血管に穿刺する。尚、上記プライミングを生理食塩水により行なう場合 もめる。 Prior to injection, first, the plunger of the syringe is pressed, and the flow path to the patient, After filling the inside of the syringe mounting part 8, spool hole 10, injection line mounting part 9, and injection line with a drug solution and removing the air inside the so-called "priming", the injection needle of the injection line is moved to the patient. Puncture the blood vessels. In addition, the case where the above priming is performed with a physiological saline is also used.
[0043] 次に、シリンジのプランジャーを押圧するのである力 S、この際、血管が確保、即ち、 確実に、注射ラインの注射針が血管に穿刺されて、注射ラインが血管に接続されて いると共に、薬液の注入速度が正規注入速度である場合には、下記のように、スプー ル 2が接続位置に保持されるので、薬液が血管内に流入し、通常通りの注射を行な る。  [0043] Next, a force S that presses the plunger of the syringe, and at this time, the blood vessel is secured, that is, the injection needle of the injection line is reliably punctured into the blood vessel, and the injection line is connected to the blood vessel. In addition, when the injection speed of the drug solution is the normal injection speed, the spool 2 is held at the connection position as described below, so that the drug solution flows into the blood vessel and performs the usual injection. .
[0044] 即ち、薬液供給停止手段の作用により、薬液の設定注入圧力以下の通常注入圧 力、つまり、注射時における、シリンジの針のゲージ、シリンジの断面積等に起因する 薬液の通常の圧力上昇、例えば、シリンジのプランジャーの摺動初期における薬液 の圧力上昇、薬液の正規注入速度等による薬液の圧力上昇によって、スプール 2の 下端面に対して、上方向の外力が作用する。しかし、この外力よりもスプール 2の摺 動開始外力は大とされているので、スプール 2が不慮に摺動する惧れはなぐ上記の ように、通常通りの注射を行なえる。  That is, due to the action of the liquid supply stop means, the normal injection pressure of the set injection pressure of the liquid medicine or less, that is, the normal pressure of the liquid medicine due to the gauge of the needle of the syringe, the cross-sectional area of the syringe, etc. at the time of injection. An upward external force acts on the lower end surface of the spool 2 due to a rise, for example, a rise in the pressure of the chemical solution at the initial stage of sliding of the plunger of the syringe, or an increase in the pressure of the chemical solution due to a normal injection speed of the chemical solution. However, since the sliding start external force of the spool 2 is set to be larger than this external force, there is no possibility that the spool 2 may slide unexpectedly.
[0045] しかし、注射時の初期において、血管が確保されていない場合、即ち、注射ライン の注射針が血管に穿刺されておらず、注射ラインが血管に接続されていない場合に は、薬液の設定注入圧力以上の大きな異常注入圧力が、流路 26を介して、スプー ノレ 2の下端面に作用し、スプール 2に作用する上方向の外力が摺動開始外力以上と なる。  However, when blood vessels are not secured in the early stage of injection, that is, when the injection needle of the injection line is not punctured in the blood vessel and the injection line is not connected to the blood vessel, A large abnormal injection pressure equal to or higher than the set injection pressure acts on the lower end surface of the spooner 2 via the flow path 26, and the upward external force acting on the spool 2 becomes equal to or greater than the sliding start external force.
[0046] これにより、スプール 2が上方向に摺動すると共に、シリンジの薬液が、チップ装着 部 8、流出ポート 13を介して、作動用流入部 21内に流入し続けて、スプール 2が図 2 に示す遮断位置となり、流入ポート 12と流出ポート 13の接続が遮断されて、報知部 2 0がハウジング 1から大きく突出する。  As a result, the spool 2 slides upward, and the drug solution of the syringe continues to flow into the working inflow section 21 through the tip mounting section 8 and the outflow port 13, and the spool 2 is moved upward. 2, the connection between the inflow port 12 and the outflow port 13 is cut off, and the notification unit 20 protrudes greatly from the housing 1.
[0047] これによつて、シリンジのプランジャーを押圧できなくなり、薬液が必要部位でない 箇所に無理に注入されないため、患者が著しい痛みを感じることもなレ、。言い換えれ ば、患者は必要な医療をスムーズに受け入れることが可能になり、且つ、薬液の血管 外への漏出に伴う治療行為などの追加的な医療行為を防ぐことができるため、医療 経済的にも効率が上がることが期待される。 [0047] As a result, the plunger of the syringe cannot be pressed, and the drug solution is not forcibly injected into a portion that is not a necessary portion, so that the patient may not feel significant pain. In other words, the patient will be able to smoothly receive the required medical treatment, It is possible to prevent additional medical activities such as medical treatment due to leakage to the outside, and it is expected that medical economics will be more efficient.
[0048] 又、上記のように、シリンジのプランジャーを押圧できなくなるので、施術者は、上記 の異常、即ち、血管が確保されていないことを容易に手元側で知ることができるが、 更に、報知部 20がハウジング 1から大きく突出するので、施術者は容易にこれを視認 でき、これによつても、血管が確保されていないことを容易に手元側で知ることができ る。  [0048] Further, as described above, since it becomes impossible to press the plunger of the syringe, the practitioner can easily know the above-mentioned abnormality, that is, that no blood vessel is secured, at the hand side. Since the notification unit 20 protrudes greatly from the housing 1, the practitioner can easily visually recognize the notification unit, and thereby can easily know at hand that a blood vessel is not secured.
[0049] この際、シリンジのプランジャーを引けば、チップ装着部 8内等の薬液をシリンジ内 に戻すこともでき、この面でも、薬液が無駄にならないようにでき、医療コストの増大を 防止できる。尚、シリンジのプランジャーを引いた際には、作動用流入部 21内の薬液 の圧力が低下して、スプール 2が接続位置に戻ることもあるが、戻らない場合には、 手でスプール 2の報知部 20を下方に押圧して、スプール 2を接続位置に戻せばよい 。このとき、注射ラインの一部を手指等により閉塞させた後、前記操作を行なえば、作 動用流入部 21内の薬液も再びシリンジ内に戻すことができる。  At this time, by pulling the plunger of the syringe, the chemical solution in the tip mounting portion 8 and the like can be returned to the syringe. In this aspect, the chemical solution can be prevented from being wasted, and an increase in medical costs can be prevented. it can. In addition, when the plunger of the syringe is pulled, the pressure of the chemical solution in the inflow portion 21 for operation may drop, and the spool 2 may return to the connection position. The notification unit 20 may be pressed downward to return the spool 2 to the connection position. At this time, if the above operation is performed after a part of the injection line is closed by a finger or the like, the drug solution in the operation inflow section 21 can be returned to the syringe again.
[0050] そして、再度、上記一連の操作を最初から行ない、血管が確保されていることを確 認した後、注射を従来同様に行なう。  [0050] Then, the above series of operations is performed again from the beginning, and after confirming that a blood vessel is secured, injection is performed as in the conventional case.
[0051] 本構成例では、上記のように、血管が確保されていない場合には、薬液を投与でき ないので、薬液の投与直前に、シリンジのプランジャーを引いて、注射ラインに血液 が逆流してくる所謂「フラッシュバック」を目視で確認して、血管が確保されているか、 否力を確認する必要がない。  [0051] In the present configuration example, as described above, if a blood vessel is not secured, a drug solution cannot be administered. Therefore, immediately before administration of the drug solution, the plunger of the syringe is pulled, and blood flows back into the injection line. It is not necessary to visually confirm the so-called “flashback” that occurs and check whether blood vessels are secured or not.
[0052] 従って、 CT検査や MRI検査等で患者が装置内部にいて、薬液を血管内に高速に 注入する必要があるような場合でも、血管外へ薬液が漏出するという不安なく検查を 行なうことが可能となる。又、薬液の投与をカテーテルを介して行なう場合でも、カテ 一テルの揷入部位によって、換言すれば、カテーテルが患者の奥深い部位に揷入さ れている場合でも、上記同様の問題が生じる惧れもない。更に、薬液の投与を行なう シリンジが、投与前にプランジャーを引くことができない場合が多い薬液充填済みシ リンジ (プレフィルドシリンジ)でも、上記のような問題が生じる惧れはなレ、。又、放射線 医薬品を投与する場合には、施術者の被曝を防止するために、シリンジや注射ライ ンも防護壁で覆われている場合があるが、そのような場合でも、血液の逆流を視覚的 に確認する必要がなレ、ので、何ら問題はなレ、。 [0052] Therefore, even when a patient is inside the apparatus in a CT examination, an MRI examination, or the like and it is necessary to inject the drug solution into the blood vessel at high speed, the test is performed without fear that the drug solution leaks out of the blood vessel. It becomes possible. In addition, even when the drug solution is administered through a catheter, the same problem as described above may occur even when the catheter is inserted into a deep part of the patient, depending on the insertion site of the catheter. Not even. Furthermore, even if a syringe that administers a drug solution does not allow the plunger to be pulled before administration in many cases, the syringe filled with the drug solution (prefilled syringe) may not cause the above-mentioned problems. When administering radiopharmaceuticals, a syringe or injection liner is used to prevent the practitioner from being exposed to radiation. In some cases, there is no need to visually check the backflow of blood, so there is no problem.
[0053] 又、薬液の種類によっては、薬液の最大注入速度が定められたものがあるが、これ に対しても、下記のように、薬液が、正規注入速度よりも速い速度で注入されることは ない。即ち、注射の初期が過ぎた後に、薬液の注入速度が正規注入速度よりも速く なると、上記同様に、薬液の設定注入圧力以上の大きな異常注入圧力が、流路 26 を介して、スプール 2の下端面に作用し、スプール 2に作用する上方向の外力が摺動 開始外力以上となる。これにより、スプール 2が遮断位置となり、薬液の注入ができな くなるので、患者に大きな負担が掛かることがないと共に、これを報知部 20が報知す るので、施術者は、薬液の注入速度が正規注入速度よりも速いことを、容易に手元側 で知ることができる。従って、施術者は、スプール 2を接続位置に戻した後、シリンジ のプランジャーを前よりも遅レ、速度で押圧し、薬液の注入速度を正規注入速度として 、薬液を注入すればよい。  [0053] Further, depending on the type of the chemical solution, there is a case where the maximum injection speed of the chemical solution is determined. However, the chemical solution is also injected at a speed higher than the normal injection speed as described below. There is nothing. That is, when the injection speed of the drug solution becomes faster than the normal injection speed after the initial stage of the injection, a large abnormal injection pressure equal to or higher than the set injection pressure of the drug solution is applied to the spool 2 via the flow path 26 as described above. The upward external force acting on the lower end surface and acting on the spool 2 is equal to or greater than the external force at which the sliding starts. As a result, the spool 2 is in the shut-off position, and the injection of the chemical liquid cannot be performed. Therefore, a large load is not applied to the patient, and the notification unit 20 notifies the user of this. Can be easily found at hand. Therefore, after returning the spool 2 to the connection position, the practitioner presses the plunger of the syringe at a slower speed than before, and injects the liquid medicine at the normal liquid injection speed.
実施例 2  Example 2
[0054] 図 3及び図 4は本発明の第 2実施例を示すもので、スプール 2の上側ランド 19の上 端部に上側シール部 31が備えられて、上側ランド 19における、両シール部 24， 31 間の距離が、スプール 2の接続位置と遮断位置間の距離よりも大とされている。これ により、スプール孔 10の内面における、下側シール部 24の摺動区域が外気による汚 染から防護されて、薬液の汚染の惧れが少なくされている。  FIGS. 3 and 4 show a second embodiment of the present invention, in which an upper seal portion 31 is provided at the upper end of the upper land 19 of the spool 2. , 31 is greater than the distance between the connecting position and the closing position of the spool 2. Thereby, the sliding area of the lower seal portion 24 on the inner surface of the spool hole 10 is protected from contamination by the outside air, and the risk of chemical liquid contamination is reduced.
実施例 3  Example 3
[0055] 図 5—図 7は本発明の第 3実施例を示すもので、スプール 2の摺動開始外力を設定 する設定機構（手段） 33が備えられて、下記のように構成されている。  FIGS. 5 to 7 show a third embodiment of the present invention, in which a setting mechanism (means) 33 for setting an external force at which the spool 2 starts sliding is provided, and is configured as follows. .
[0056] 即ち、スプール 2の報知部 20の軸心方向中途部には、径方向外方に突出する周 突起 34がー体形成されてレ、る。  That is, a circumferential projection 34 protruding outward in the radial direction is formed at an intermediate portion of the notification section 20 of the spool 2 in the axial center direction.
[0057] 又、ハウジング 1の筒部 7の上端部には、スプール 2の報知部 20の上部に外嵌され る調整筒 35が外嵌、固定されている。調整筒 35は、弾性変形可能な材料により一体 形成されており、その下部の外周面には、上方に向かってテーパー状とされたテー パー螺子部 36が形成されている。又、調整筒 35の内周面の軸心方向中途部には、 径方向内方に突出する周突起 37がー体形成され、この周突起 37が、スプール 2の 周突起 34の上方に配設されている。更に、調整筒 35の上端から周突起 34の下端に わたる部分には、径方向に貫通形成されたスリット 45が配設されている。調整筒 35 の構成材料としては、スプール 2と同様なものが用いられる。 An adjusting cylinder 35 externally fitted to the upper part of the notification section 20 of the spool 2 is externally fitted and fixed to the upper end of the cylindrical section 7 of the housing 1. The adjusting cylinder 35 is integrally formed of a material that can be elastically deformed, and a tapered screw portion 36 that is tapered upward is formed on an outer peripheral surface of a lower portion thereof. Also, in the axial center part of the inner peripheral surface of the adjustment cylinder 35, A circumferential projection 37 protruding radially inward is formed, and the circumferential projection 37 is disposed above the circumferential projection 34 of the spool 2. Further, a slit 45 penetrating in the radial direction is provided in a portion extending from the upper end of the adjusting cylinder 35 to the lower end of the peripheral projection 34. As the constituent material of the adjusting cylinder 35, the same material as that of the spool 2 is used.
[0058] 蓋体 5は調整筒に外嵌されて、その内周の雌螺子部 38がテーパー螺子部 36に螺 合されており、図 5及び図 7に示すように、蓋体 5の調整筒 35に対する螺進退により、 調整筒 35のスリット 45が周方向に拡縮して、周突起 37の内径が拡縮する。尚、調整 筒 35に、テーパー螺子部 36ではなぐ通常の螺子部を形成し、蓋体 5にテーパー螺 子部を形成してもよい。 The cover 5 is externally fitted to the adjusting cylinder, and the female screw portion 38 on the inner periphery thereof is screwed to the tapered screw portion 36. As shown in FIGS. 5 and 7, the adjustment of the cover 5 is performed. By the screw advance / retreat with respect to the cylinder 35, the slit 45 of the adjustment cylinder 35 expands and contracts in the circumferential direction, and the inner diameter of the peripheral projection 37 expands and contracts. It is to be noted that a normal screw portion that is not connected to the tapered screw portion 36 may be formed in the adjustment cylinder 35, and a tapered screw portion may be formed in the lid 5.
[0059] 上記構成例では、スプール 2が、図 5に示す接続位置から図 6に示す遮断位置に 移動する際には、調整筒 35の周突起 37及び/又はスプール 2の周突起 34が弾性 変形して、スプール 2の周突起 34が調整筒 35の周突起 37の内部を通過する必要が ある。従って、図 5及び図 7に示すように、調整筒 35の周突起 37の内径を拡縮するこ とにより、スプール 2の周突起 34が調整筒 35の周突起 37の内部を通過するに必要 な外力、即ち、摺動開始外力を自由に設定できる。  In the above configuration example, when the spool 2 moves from the connection position shown in FIG. 5 to the shut-off position shown in FIG. 6, the circumferential protrusion 37 of the adjusting cylinder 35 and / or the circumferential protrusion 34 of the spool 2 are elastic. It is necessary that the peripheral projection 34 of the spool 2 be deformed and pass through the inside of the peripheral projection 37 of the adjusting cylinder 35. Therefore, as shown in FIGS. 5 and 7, by expanding and contracting the inner diameter of the peripheral projection 37 of the adjustment cylinder 35, it is necessary for the peripheral projection 34 of the spool 2 to pass through the inside of the peripheral projection 37 of the adjustment cylinder 35. The external force, that is, the external force for starting the sliding can be set freely.
実施例 4  Example 4
[0060] 図 8及び図 9は本発明の第 4実施例を示すもので、ハウジング 1が、本体 4と、注射 ライン装着体 39と、蓋体 5等を有する。  FIG. 8 and FIG. 9 show a fourth embodiment of the present invention, in which a housing 1 has a main body 4, an injection line mounting body 39, a lid 5, and the like.
[0061] 流入ポート 12は筒部 7の下部に形成されており、図 8に示すように、スプール 2が接 続位置にある時には、スプール 2のグループ 25と連通する力 図 9に示すように、ス プール 2が遮断位置にある時には、作動用流入部 21と連通する。又、流出ポート 13 は、流入ポート 12よりも上位とされ、常時、スプール 2のグループ 25と連通している。 筒部 7には、流入ポート 12の下方に位置する入口側作動ポート 40が左右方向に貫 通形成され、チップ装着部 8と作動用流入部 21を連通している。  [0061] The inflow port 12 is formed at the lower portion of the cylindrical portion 7, and as shown in Fig. 8, when the spool 2 is in the connection position, the force for communicating with the group 25 of the spool 2 as shown in Fig. 9 When the spool 2 is in the shut-off position, it communicates with the operating inlet 21. The outflow port 13 is higher than the inflow port 12 and is always in communication with the group 25 of the spool 2. An inlet-side operation port 40 located below the inflow port 12 is formed in the cylindrical portion 7 so as to penetrate in the left-right direction, and communicates the tip mounting portion 8 and the operation inflow portion 21.
[0062] 注射ライン装着体 39は、上下方向に関して、チップ装着部 8と略同一位置に配置 することができ、筒部 7の左側面に固設されて、これら両者間には、上下方向の連絡 路 41が形成され、この連絡路 41と流出ポート 13が連通すると共に、注射ライン装着 体 39の右端部に、連絡路 41及び注射ライン装着体 39内部と連通する連通孔 42が 左右方向に貫通形成されてレ、る。 [0062] The injection line mounting body 39 can be arranged at substantially the same position as the tip mounting portion 8 in the vertical direction, is fixed to the left side surface of the cylindrical portion 7, and has a vertical direction between them. A communication channel 41 is formed, the communication channel 41 communicates with the outflow port 13, and a communication hole 42 communicating with the communication channel 41 and the inside of the injection line mounting body 39 is provided at the right end of the injection line mounting body 39. It is formed to penetrate in the left-right direction.
[0063] 又、スプール 2の下側ランド 17の軸心方向長さは小とされている。尚、シール部 43 は複数であっても良いが、シール性を増すために、好ましくは、単一とされると共に、 スプール 2の下端面には、対向部 11と当接する突起 44が形成されており、スプール 2が接続位置にある時にも、スプール 2の下端面の大部分は対向部 11から離間して いる。  The length of the lower land 17 of the spool 2 in the axial direction is small. In addition, a plurality of the seal portions 43 may be provided, but in order to increase the sealing performance, the spool portions are preferably single, and a projection 44 is formed on the lower end surface of the spool 2 to be in contact with the facing portion 11. When the spool 2 is in the connection position, most of the lower end surface of the spool 2 is separated from the facing portion 11.
[0064] 上記構成例によれば、注射時に、薬液の注入圧力が設定注入圧力以上になると、 チップ装着部 8内の薬液が、まず、入口側作動ポート 40を介して、作動用流入部 21 内に流入して、スプール 2が上方に摺動を開始する。その後、流入ポート 12とスプー ノレ 2のグループ 25との連通が遮断されて、流入ポート 12も作動用流入部 21と連通し 、流入ポート 12からも薬液が作動用流入部 21内に流入する。これにより、スプール 2 が、図 9に示す所定の遮断位置に摺動する。  According to the above configuration example, when the injection pressure of the drug solution becomes equal to or higher than the set injection pressure at the time of injection, the drug solution in the tip mounting section 8 firstly flows through the inlet-side operation port 40 through the operation inflow section 21. And the spool 2 starts sliding upward. Thereafter, the communication between the inflow port 12 and the group 25 of the spoonhole 2 is cut off, the inflow port 12 also communicates with the operating inflow section 21, and the chemical solution flows from the inflow port 12 into the operating inflow section 21. As a result, the spool 2 slides to the predetermined blocking position shown in FIG.
実施例 5  Example 5
[0065] 図 10—図 12は本発明の第 5実施例を示すもので、チップ装着部 8と注射ライン装 着部 9、流入ポート 12と流出ポート 13が、夫々、上下方向に関して、 （略）同一位置と されている。又、下側ランド 17の上 '下シール部 23, 22間に、軸心方向の縦シール 部 46が周方向等間隔に配設されて、上 ·下シール部 23, 22間が複数の区画室 47 に区画されており、スプール 2が遮断位置になった際に、流入ポート 12と流出ポート 13が、夫々、異なる区画室 47に連通して、流入ポート 12と流出ポート 13の接続が遮 断される。  FIGS. 10 to 12 show a fifth embodiment of the present invention, in which the tip mounting section 8 and the injection line mounting section 9, the inflow port 12 and the outflow port 13 are arranged in the up-down direction (substantially). ) The same position. In addition, longitudinal seal portions 46 in the axial direction are arranged at equal intervals in the circumferential direction between the upper and lower seal portions 23 and 22 of the lower land 17, and a plurality of partitions are provided between the upper and lower seal portions 23 and 22. When the spool 2 is in the shut-off position, the inflow port 12 and the outflow port 13 communicate with different compartments 47, respectively, and the connection between the inflow port 12 and the outflow port 13 is interrupted. Refused.
実施例 6  Example 6
[0066] 図 13及び図 14は本発明の第 6実施例を示すもので、上記第 4実施例と同様に、ハ ウジング 1が、本体 4と、注射ライン装着体 39と、蓋体 5等を有するが、その相違点の みを次に説明する。  FIGS. 13 and 14 show a sixth embodiment of the present invention. As in the fourth embodiment, the housing 1 includes the main body 4, the injection line mounting body 39, the lid 5 and the like. However, only the differences will be described below.
[0067] まず、流入ポート 12は筒部 7の上下方向中途部に形成されて、スプール 2のグルー ブ 25と、常時、連通している。又、流出ポート 13は、筒部 7の下部側に形成されて、 流入ポート 12よりも下位とされ、図 13に示すように、スプール 2が接続位置にある時 には、スプール 2のグループ 25と連通する力 図 14に示すように、スプール 2が遮断 位置にある時には、作動用流入部 21と連通する。 First, the inflow port 12 is formed in the middle part of the cylindrical portion 7 in the vertical direction, and is always in communication with the groove 25 of the spool 2. The outflow port 13 is formed on the lower side of the cylindrical portion 7 and is lower than the inflow port 12. As shown in FIG. 13, when the spool 2 is in the connection position, the group of the spool 2 Spool 2 shuts off as shown in Fig. 14 When in the position, it communicates with the actuation inlet 21.
[0068] 筒部 7には、流出ポート 13の下方に位置する出口側作動ポート 49が左右方向に貫 通形成され、作動用流入部 21と連通している。そして、筒部 7と注射ライン装着体 39 間の連絡路 41が、流出ポート 13及び出口側作動ポート 49と連通している。又、ハウ ジング 1の対向部 11における、主要部、即ち、外周部を除く部分 (又は、全部）が、ゴ ム等の弾性材料から成る補助体 50とされている。  [0068] An outlet-side operation port 49 located below the outflow port 13 is formed through the cylindrical portion 7 in the left-right direction, and communicates with the inflow portion 21 for operation. A communication path 41 between the cylinder 7 and the injection line mounting body 39 communicates with the outflow port 13 and the outlet-side operation port 49. In addition, a main part, that is, a part (or all) of the facing part 11 of the housing 1 except for an outer peripheral part is an auxiliary body 50 made of an elastic material such as rubber.
[0069] 上記構成例によれば、注射時に、薬液の注入圧力が設定注入圧力以上になると、 注射ライン装着体 39内の薬液が、まず、出口側作動ポート 49を介して、作動用流入 部 21内に流入して、この薬液の圧力により、補助体 50が下方に弾性変形する。その 後、薬液の圧力により、スプール 2が上方に摺動して、流出ポート 13とグループ 25の 接続が遮断されると共に、流出ポート 13が作動用流入部 21と連通する。そして、薬 液の圧力と、補助体 50の弾性復元力とにより、スプール 2が更に上方に摺動して、ス プール 2が、図 14に示す所定の遮断位置となる。  According to the above configuration example, when the injection pressure of the drug solution becomes equal to or higher than the set injection pressure at the time of injection, the drug solution in the injection line mounting body 39 firstly flows through the outlet side operation port 49 through the operation inflow section. The auxiliary body 50 flows into the inside 21 and is elastically deformed downward by the pressure of the chemical solution. Thereafter, the spool 2 slides upward due to the pressure of the chemical solution, so that the connection between the outflow port 13 and the group 25 is cut off, and the outflow port 13 communicates with the inflow section 21 for operation. Then, due to the pressure of the chemical solution and the elastic restoring force of the auxiliary body 50, the spool 2 slides further upward, and the spool 2 comes to a predetermined blocking position shown in FIG.
[0070] 上記構成例では、スプール 2が摺動して、流出ポート 13とグループ 25の接続が遮 断されると、チップ装着部 8側から作動用流入部 21内に薬液が供給されないため、ス プール 2の所定の遮断位置までの『確実な摺動』に、一見、問題があるように考えられ るが、補助体 50の上記作用により、スプール 2は所定の遮断位置まで確実に摺動す る。尚、本例において、補助体 50が無くても、実際上は、問題がないが、より信頼性 を高めるために、補助体 50を具備させている。  In the above configuration example, when the spool 2 slides and the connection between the outflow port 13 and the group 25 is interrupted, the chemical liquid is not supplied from the tip mounting portion 8 side into the working inflow portion 21. At first glance, it seems that there is a problem in the “reliable sliding” of the spool 2 to the predetermined shut-off position, but the spool 2 reliably slides to the predetermined shut-off position due to the above-described operation of the auxiliary body 50. You. In this example, there is no problem in practice without the auxiliary body 50, but the auxiliary body 50 is provided to further enhance the reliability.
実施例 7  Example 7
[0071] 図 15及び図 16は本発明の第 7実施例を示し、上記第 1実施例の変形例であって、 その相違点のみを次に説明する。まず、チップ装着部 8が注射ライン装着部 9よりも 若干上位とされている。流出ポート 13は、出口側作動ポートと兼用とされるもので、筒 部 7の下端部に形成されて、常時、作動用流入部 21と連通している。又、ハウジング 1の対向部 11における、主要部、即ち、外周部を除く部分 (又は、全部）が、ゴム等の 弾性材料力 成る補助体 50とされている。更に、スプール 2の下端面には、対向部 1 1と当接する突起 44が形成されており、スプール 2が接続位置にある時にも、スプー ノレ 2の下端面の大部分は対向部 11から離間している。 [0072] 上記構成例によれば、注射時に、流入ポート 12からスプール 2のグループ 25内に 流入した薬液は、流路 26、作動用流入部 21、流出ポート 13を介して、注射ライン装 着部 9内に流入する。この際、薬液の注入圧力が設定注入圧力以上になると、作動 用流入部 21内の薬液の圧力により、補助体 50が下方に弾性変形する。その後、薬 液の圧力により、スプール 2が上方に摺動して、流入ポート 12とグループ 25の連通 が遮断される。そして、薬液の圧力と、補助体 50の弾性復元力とにより、スプール 2 が更に上方に摺動して、スプール 2が、図 16に示す所定の遮断位置となる。尚、本 例においても、補助体 50が無くても、実際上は、問題がないが、より信頼性を高める ために、補助体 50を具備させている。 FIGS. 15 and 16 show a seventh embodiment of the present invention, which is a modification of the first embodiment, and only the differences will be described below. First, the tip mounting section 8 is slightly higher than the injection line mounting section 9. The outflow port 13 is also used as an outlet-side operation port, and is formed at the lower end of the cylindrical portion 7 and is always in communication with the operation inflow portion 21. In addition, a main portion, that is, a portion (or all) of the opposing portion 11 of the housing 1 except for the outer peripheral portion is an auxiliary body 50 made of an elastic material such as rubber. Further, a projection 44 is formed on the lower end surface of the spool 2 so as to be in contact with the facing portion 11. Even when the spool 2 is at the connection position, most of the lower end surface of the spoonlet 2 is separated from the facing portion 11. are doing. [0072] According to the above configuration example, at the time of injection, the chemical solution flowing from the inflow port 12 into the group 25 of the spool 2 is attached to the injection line via the flow path 26, the inflow section 21 for operation, and the outflow port 13. Flows into part 9. At this time, if the injection pressure of the chemical solution is equal to or higher than the set injection pressure, the auxiliary body 50 is elastically deformed downward by the pressure of the chemical solution in the working inflow portion 21. Thereafter, the spool 2 slides upward due to the pressure of the chemical solution, and the communication between the inflow port 12 and the group 25 is cut off. Then, due to the pressure of the chemical solution and the elastic restoring force of the auxiliary body 50, the spool 2 slides further upward, and the spool 2 comes to a predetermined blocking position shown in FIG. It should be noted that, even in the present example, there is actually no problem even if the auxiliary body 50 is not provided, but the auxiliary body 50 is provided to further enhance reliability.
[0073] 尚、図 13及び図 14では、流出ポートと出口側作動ポートを別々に設けた力 図 1 一図 11、図 15及び図 16のように、流出ポートと出口側作動ポートを兼用としてもよい 。又、図 8及び図 9では、流入ポートと入口側作動ポートを別々に設けたが、図 1一図 7、図 10、図 11、図 13—図 16のように、流入ポートと入口側作動ポートを兼用として あよい。  [0073] In Figs. 13 and 14, the force of separately providing the outflow port and the outlet-side operation port is used as shown in Figs. 11, 15, and 16. May be. In addition, in Fig. 8 and Fig. 9, the inflow port and the inlet side operation port are provided separately. However, as shown in Fig. 1, Fig. 7, Fig. 10, Fig. 11, Fig. 13-Fig. The port can be shared.
実施例 8  Example 8
[0074] 図 17—図 24は本発明の第 8実施例を示し、薬液供給制御装置は、ハウジング 1や スプール 2の他に、操作手段 3も有する。ハウジング 1の本体 4は透明とされているが 、ハウジング 1の蓋体 5も透明とされることがある。  FIG. 17 to FIG. 24 show an eighth embodiment of the present invention. The chemical liquid supply control device has an operating means 3 in addition to the housing 1 and the spool 2. Although the main body 4 of the housing 1 is transparent, the lid 5 of the housing 1 may be transparent.
[0075] スプール 2は、図 22に示す接続位置と、図 23に示す遮断位置とに位置変更自在と されている。スプール 2は、下端部 117と、下側ランド 118と、中間部 119と、上側ラン ド 120と、ストッパ部 121と、報知部 122と、軸部 123を、上記の順で、上方に向かつ て連設（一体形成）することで、構成されている。上側'下側ランド 120, 118は同径と され、スプール 2の他の部分は、これらよりも小径とされてレ、る。下端部 117と下側ラン ド 118の下端面は、ハウジング 1の対向部 11と上下方向に関して対向し、これらの間 が作動用流入部 124とされて、この作動用流入部 124に作動用ポート 14が連通して いる力 スプール 2が接続位置にある時には、下端部 117は対向部 11と当接してい る。尚、作動用ポート 14により、薬液供給停止手段が構成されるが、この薬液供給停 止手段に作動用流入部 124を含めることもある。 [0076] 下側ランド 118と上側ランド 120の外周部は、シール部として、スプール孔 10の内 面に軸心方向に摺動自在に液密状態 (気密状態)で当接 (圧接)している。尚、上記 当接により、スプール 2は任意の摺動位置で保持可能とされており、摺動開始外力（ 設定外力）以上の大きさの外力がスプール 2に上下方向に作用した際に、スプール 2 が摺動可能とされている。即ち、下側ランド 118と上側ランド 120の外周のシール部 は、上記摺動開始外力を定める設定手段としての機能も有している。これらシール部 は、通常、下側ランド 118と上側ランド 120と一体形成される力 別体とされたシール 部材により構成される場合もある。 The position of the spool 2 can be freely changed between a connection position shown in FIG. 22 and a shut-off position shown in FIG. The spool 2 includes a lower end portion 117, a lower land 118, an intermediate portion 119, an upper land 120, a stopper portion 121, a notification portion 122, and a shaft portion 123, which are directed upward in the above order. And is formed continuously (integrally formed). The upper and lower lands 120 and 118 have the same diameter, and the other parts of the spool 2 have smaller diameters. The lower end portion 117 and the lower end surface of the lower land 118 are opposed to the opposing portion 11 of the housing 1 in the up-down direction, and a space therebetween is defined as an operation inflow portion 124. When the spool 2 is in the connected position, the lower end portion 117 is in contact with the facing portion 11. Although the chemical liquid supply stopping means is constituted by the operating port 14, the chemical liquid supply stopping means may include the operating inflow portion 124. The outer periphery of the lower land 118 and the outer periphery of the upper land 120, as a seal portion, abut (press) against the inner surface of the spool hole 10 in a liquid-tight state (air-tight state) so as to be slidable in the axial direction. I have. The contact makes it possible to hold the spool 2 at an arbitrary sliding position. When an external force greater than the external force at the start of sliding (set external force) acts on the spool 2 in the vertical direction, the spool 2 2 is slidable. That is, the seal portions on the outer periphery of the lower land 118 and the upper land 120 also have a function as setting means for determining the above-mentioned sliding start external force. In some cases, these seal portions are usually constituted by a seal member which is formed integrally with the lower land 118 and the upper land 120 and is a force.
[0077] 下側ランド 118と上側ランド 120間、即ち、中間部 119の径方向外方側は、グルー ブ（周溝） 125とされ、流入ポート 12とは、常時、連通している力 流出ポート 13とは、 スプール 2が接続位置にある時のみ、連通している。  [0077] A groove (circumferential groove) 125 is formed between the lower land 118 and the upper land 120, that is, the radially outer side of the intermediate portion 119, and the force that is always in communication with the inflow port 12 It communicates with port 13 only when spool 2 is in the connection position.
[0078] ストッパ部 121の上面は、スプール 2が遮断位置にある時に、蓋体 5の下端面と当 接する。  The upper surface of the stopper portion 121 contacts the lower end surface of the lid 5 when the spool 2 is at the blocking position.
[0079] 軸部 123は、報知部 122よりも小径とされて、その中間部に、全周にわたって、径方 向外方に湾曲状に突出するリング部 127が形成されており、このリング部 127と報知 部 122間が周溝 128とされている。  [0079] The shaft portion 123 has a smaller diameter than the notification portion 122, and a ring portion 127 that protrudes radially outward in a curved shape is formed in the middle portion thereof over the entire circumference. A circumferential groove 128 is formed between 127 and the notification unit 122.
[0080] 操作手段 3は、後述する係合手段と共に、薬液供給手段から注射ラインへの薬液 供給に関する不具合を報知する不具合報知手段を構成するが、この不具合報知手 段は、報知部 122により構成される不具合報知手段とは別個とされている。操作手段 3は、支持台 130と、梃子 131と、復帰用バネ 132を有する。支持台 130は、ハウジン グ 1の蓋体 5に一体形成されると共に、この支持台 130には支持部 133が立設されて おり、この支持部 133からは前後に一対の支持軸 134が突設されている。梃子 131 は、その長手方向中途部が支持部 133に載置されると共に、支持軸 134に弾性変形 を介して係脱自在に係合されており、支持軸 134により、ハウジング 1に揺動自在に 枢支されている。又、梃子 131の先端部は、 2股状の係合部 135とされて、この係合 部 135の前後両側部がスプールの周溝 128に係脱自在に係合されており、これら係 合部 135と周溝 128により、操作手段 3とスプールを係脱自在に係合する係合手段 が構成されている。この係合手段の係合を解除させるためには、係合部 135に上向 きの設定操作力以上の外力を作用させて、係合部 135にリング部 127を乗り越えさ せる必要がある。尚、上記設定操作力は、スプール 2の摺動開始外力よりも大とされ ている。復帰用パネ 132は揺動後の梃子 131を原位置に復帰させるもので、梃子 13 1の基部に湾曲状に一体形成されて、梃子 131の基部と支持台 130間に弾発状に 介装されて、梃子 131の基部を上方に付勢している。 The operating means 3 constitutes, together with the engaging means described later, a malfunction notifying means for notifying a malfunction relating to the supply of the medicinal solution from the medicinal solution supplying means to the injection line. This is separate from the malfunction notification means to be performed. The operating means 3 includes a support 130, a lever 131, and a return spring 132. The support 130 is formed integrally with the lid 5 of the housing 1, and a support 133 is erected on the support 130, and a pair of support shafts 134 project forward and backward from the support 133. Is established. The lever 131 has its middle part in the longitudinal direction placed on the support part 133 and is engaged with the support shaft 134 so as to be able to freely engage and disengage via elastic deformation. It is pivoted. The distal end of the lever 131 is formed as a bifurcated engagement portion 135, and the front and rear sides of the engagement portion 135 are engaged with the circumferential groove 128 of the spool so as to be freely detachable. The engagement means for releasably engaging the operating means 3 with the spool is constituted by the portion 135 and the circumferential groove 128. In order to release the engagement of the engagement means, it is necessary to It is necessary to apply an external force equal to or greater than the set operation force to move the engagement portion 135 over the ring portion 127. Note that the set operation force is set to be larger than the external force at which the spool 2 starts sliding. The return panel 132 is for returning the lever 131 after swinging to its original position. The return panel 132 is integrally formed in a curved shape at the base of the lever 131, and is elastically interposed between the base of the lever 131 and the support 130. Thus, the base of the lever 131 is urged upward.
[0081] 上記構成例では、注射時には、注射ライン装着部 9に、シリンジのチップに装着可 能な注射針、既に血管に留置された留置針、或いは、カテーテル力 延びる注射ラ インが装着され、一方、チップ装着部 8に、薬液供給手段として、薬液が充填された シリンジのチップが装着される。又、スプール 2は図 22に示す接続位置にあって、そ のグループ 125により、流入ポート 12と流出ポート 13が接続されている。  [0081] In the above configuration example, at the time of injection, an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment section 9, On the other hand, a tip of a syringe filled with a drug solution is mounted on the tip mounting section 8 as a drug solution supply means. The spool 2 is at the connection position shown in FIG. 22, and the inflow port 12 and the outflow port 13 are connected by the group 125.
[0082] 注射前には、まず、シリンジのプランジャーを押圧して、患者までの流路、即ち、チ ップ装着部 8、スプール孔 10、注射ライン装着部 9及び注射ライン内部に薬液を充填 して、上記内部の空気を除去する所謂「プライミング」を行なった後、注射ラインの注 射針を患者の血管に穿刺する。尚、上記プライミングを生理食塩水により行なう場合 もめる。  Prior to injection, first, the plunger of the syringe is pressed, and the drug solution is injected into the flow path to the patient, that is, into the tip mounting portion 8, the spool hole 10, the injection line mounting portion 9, and the inside of the injection line. After filling and performing the so-called “priming” for removing the internal air, the injection needle of the injection line is punctured into the blood vessel of the patient. In addition, the case where the above priming is performed with a physiological saline is also used.
[0083] 次に、血管が確保されているカ 否かを確認するために、梃子 131の基部を押し下 げて、スプール 2に対して、上向きの操作力を加える。この際、血管が確保、即ち、確 実に、注射ラインの注射針が血管に穿刺されて、注射ラインが血管に接続されている 場合 (換言すれば、注射ラインが開放状態である場合）には、図 23に示すように、ス プール 2が上方に摺動し、これに伴って発生する負圧により、注射ライン内の薬液等 力 先ず、作動ポート 14を介して、作動用流入部 124に流入し、次に、作動ポート 14 及び流出ポート 13を介して、作動用流入部 124に流入する。これにより、注射ライン に血液が逆流してくる所謂「フラッシュバック」を目視でき、血管が確保されていること を確認できる。そして、梃子 131の操作力を解除すると、梃子 131は復帰用パネ 132 により原位置に揺動し、スプール 2が薬液を注射ライン装着部に押し出しながら下降 して、接続位置に戻る。これにより、通常通りの注射を行なえる。  Next, in order to confirm whether or not the blood vessel is secured, the base of the lever 131 is pushed down, and an upward operating force is applied to the spool 2. At this time, when the blood vessel is secured, that is, when the injection needle of the injection line is surely pierced into the blood vessel and the injection line is connected to the blood vessel (in other words, when the injection line is open), As shown in FIG. 23, the spool 2 slides upward, and the negative pressure generated due to this causes the chemical solution in the injection line to first move into the working inflow portion 124 through the working port 14. It flows into the working inlet 124 through the working port 14 and the outlet port 13. This makes it possible to visually observe the so-called “flashback” in which blood flows back to the injection line, and confirm that blood vessels are secured. Then, when the operating force of the lever 131 is released, the lever 131 is swung to the original position by the return panel 132, and the spool 2 descends while pushing out the liquid medicine to the injection line mounting portion, and returns to the connection position. This allows a normal injection to be made.
[0084] 又、梃子 131の基部を押し下げて、スプール 2に上向きの操作力をカ卩えた際に、血 管が確保されていない場合、即ち、注射ラインの注射針が血管に穿刺されておらず、 注射ラインが血管に接続されていない場合 (換言すれば、注射ラインが閉鎖状態で ある場合）には、スプール 2を上方に摺動させることができず、注射ライン内の薬液等 を作動用流入部 124内に吸引できない。そして、梃子 131の操作力が設定操作カ以 上になると、図 24に示すように、挺子 131のィ系合咅 力 Sスプーノレ 2の周溝 128力ら 離脱し、リング部 127を乗り越えて、その上方に移動し、これにより、施術者は、血管 が確保されていないことを容易に知ることができる。そして、梃子 131の操作力を解 除すると、復帰用パネ 132により、梃子 131の基部が上方に揺動しょうとするが、梃子 131の係合部 135がスプール 2のリング部 127に当接してレ、るため、梃子 131は原位 置に復帰せず、この梃子 131の位置からも、血管が確保されていないことを視認でき る。 [0084] Further, when the base of the lever 131 is pushed down and the upward operation force is applied to the spool 2, when the blood vessel is not secured, that is, when the injection needle of the injection line is punctured into the blood vessel. Not When the injection line is not connected to a blood vessel (in other words, when the injection line is in a closed state), the spool 2 cannot be slid upward, and the drug solution or the like in the injection line flows for operation. It cannot be sucked into the part 124. Then, when the operating force of the lever 131 exceeds the set operating force, as shown in FIG. 24, the lever 131 is separated from the joint force S of the spoonor 2 from the circumferential groove 128 force, and climbs over the ring portion 127. Then, the operator moves upward, whereby the practitioner can easily know that the blood vessel is not secured. Then, when the operating force of the lever 131 is released, the base of the lever 131 tries to swing upward by the return panel 132, but the engaging portion 135 of the lever 131 comes into contact with the ring portion 127 of the spool 2 so as to come into contact. Therefore, the lever 131 does not return to the original position, and it can be visually confirmed from the position of the lever 131 that no blood vessel is secured.
[0085] これによつて、施術者がシリンジのプランジャーを押圧しないので、薬液が必要部 位でない箇所に無理に注入されることがなぐ患者が著しい痛みを感じることもなレ、。 換言すれば、患者は必要な医療をスムーズに受け入れることが可能になり、且つ、薬 液の血管外への漏出に伴う治療行為などの追加的な医療行為を防ぐことができるた め、医療経済的にも効率が上がることが期待される。  [0085] As a result, since the practitioner does not press the plunger of the syringe, the patient does not forcibly inject the medicinal solution into a non-necessary location, and the patient does not feel any significant pain. In other words, the patient can smoothly receive the required medical treatment, and can prevent additional medical treatment such as treatment due to leakage of the drug solution out of the blood vessel. It is expected that the efficiency will also increase.
[0086] 上記のように、施術者は、血管が確保されていないことを容易に手元側で知ること ができるので、再度、上記一連の操作を最初から行ない、血管が確保されていること を確認した後、注射を下記のように従来同様に行なう。  [0086] As described above, the practitioner can easily know at hand that a blood vessel has not been secured, so that the above-described series of operations is performed again from the beginning to confirm that the blood vessel has been secured. After confirmation, injections are performed conventionally as described below.
[0087] 即ち、シリンジのプランジャーを押圧するのである力 この際、薬液の注入速度が正 規注入速度である場合には、スプール 2が接続位置に保持されるので、薬液が血管 内に流入し、通常通りの注射を行なえる。  [0087] That is, the force that presses the plunger of the syringe. At this time, if the injection speed of the drug solution is the normal injection speed, the spool 2 is held at the connection position, and the drug solution flows into the blood vessel. And perform the usual injections.
[0088] この場合において、薬液の設定注入圧力以下の通常注入圧力、つまり、注射時に おける、シリンジの針のゲージ、シリンジの断面積等に起因する薬液の通常の圧力上 昇、例えば、シリンジのプランジャーの摺動初期における薬液の圧力上昇、薬液の正 規注入速度等による薬液の圧力上昇により、出口側作動ポート 14を介して、スプー ル 2の下端面に、上方向の外力が作用する。しかし、この外力よりもスプール 2の摺動 開始外力は大とされているので、スプール 2が不慮に摺動する惧れはなぐ上記のよ うに、通常通りの注射を行なえる。 [0089] 又、薬液の種類によっては、薬液の最大注入速度が定められたものがあるが、これ に対しても、下記のように、薬液が、正規注入速度よりも速い速度で注入されることは ない。即ち、薬液の注入速度が正規注入速度よりも速くなると、注射ライン装着部 9内 の薬液が、まず、出口側作動ポート 14を介して、作動用流入部 124内に流入し、この 薬液の圧力がスプール 2に作用して、スプール 2に作用する上方向の外力が摺動開 始外力以上となる。これにより、図 23に示すように、スプール 2が上方に摺動して、遮 断位置となると共に、梃子 131が揺動し、薬液の注入ができなくなるので、患者に大 きな負担が掛カ、ることがなぐしかも、これを、蓋体から上方に大きく突出した報知部 1 22及び揺動した梃子 131が報知するので、施術者は、薬液の注入速度が正規注入 速度よりも速いことを、容易に手元側で知ることができる。従って、施術者は、梃子 13 1、又は、スプール 2の押圧により、スプール 2を接続位置に戻した後、シリンジのプラ ンジャーを前よりも遅い速度で押圧し、薬液の注入速度を正規注入速度として、薬液 を注入すればよい。 [0088] In this case, the normal injection pressure equal to or lower than the set injection pressure of the drug solution, that is, the normal pressure increase of the drug solution due to the gauge of the syringe needle, the cross-sectional area of the syringe, etc. during injection, for example, the syringe Due to an increase in the chemical pressure at the initial stage of sliding of the plunger and an increase in the chemical pressure due to the regular injection speed of the chemical, an upward external force acts on the lower end surface of the spool 2 through the outlet-side operation port 14. . However, since the external force at which the spool 2 starts to slide is larger than this external force, there is no fear that the spool 2 will slide unexpectedly. [0089] In addition, depending on the type of the liquid medicine, the maximum injection rate of the liquid medicine is determined, but the liquid medicine is also injected at a speed higher than the normal injection speed as described below. There is nothing. That is, when the injection speed of the drug solution becomes faster than the normal injection speed, the drug solution in the injection line mounting portion 9 first flows into the working inflow portion 124 through the outlet-side working port 14, and the pressure of the drug solution is increased. Acts on the spool 2, and the upward external force acting on the spool 2 becomes equal to or greater than the external force at the start of sliding. As a result, as shown in FIG. 23, the spool 2 slides upward to be in the cut-off position, and the lever 131 swings, so that the injection of the medicinal solution cannot be performed. In addition, since the notifying unit 122 and the swinging lever 131 that project greatly upward from the lid inform the user of this, the practitioner must make sure that the injection speed of the drug solution is higher than the normal injection speed. Can be easily known at hand. Therefore, after returning the spool 2 to the connection position by pressing the lever 131 or the spool 2, the practitioner presses the syringe plunger at a lower speed than before, so that the injection speed of the drug solution becomes the normal injection speed. Then, a chemical solution may be injected.
[0090] 従って、 CT検査や MRI検査等で患者が装置内部にいて、薬液を血管内に高速に 注入する必要があるような場合でも、血管外へ薬液が漏出するという不安なく検査を 行なうことが可能となる。又、薬液の投与をカテーテルを介して行なう場合でも、カテ 一テルの挿入部位によって、換言すれば、カテーテルが患者の奥深い部位に挿入さ れている場合でも、上記同様の問題が生じる惧れもない。更に、薬液の投与を行なう シリンジが、投与前にプランジャーを引くことができない場合が多い薬液充填済みシ リンジ (プレフィルドシリンジ)でも、上記のような問題が生じる惧れはない。又、放射線 医薬品を投与する場合には、施術者の被曝を防止するために、シリンジや注射ライ ンも防護壁で覆われている場合があるが、そのような場合でも、血液の逆流を視覚的 に確認する必要がなレ、ので、何ら問題はなレ、。  [0090] Therefore, even when a patient is inside the apparatus and it is necessary to inject a drug solution into a blood vessel at a high speed by a CT or MRI test, the test should be performed without fear that the drug solution leaks out of the blood vessel. Becomes possible. In addition, even when the drug solution is administered via a catheter, even if the catheter is inserted into a deep part of the patient, depending on the insertion site of the catheter, the same problem as described above may occur. Absent. Further, even in a syringe for administering a drug solution, a syringe filled with a drug solution (a prefilled syringe) that often cannot pull a plunger before administration does not cause the above-described problem. In addition, when administering radiopharmaceuticals, syringes and injection lines may be covered with protective walls in order to prevent exposure of the practitioner. There is no need to check specifically, so there is no problem.
実施例 9  Example 9
[0091] 図 25—図 27は本発明の第 9実施例を示すもので、ハウジング 1のスプール孔 10が 、下部側の小径部 141と、この小径部 141よりも大径とされた上部側の大径部 142か ら成る。又、スプール 2は、下端部 117と、下側小径ランド 143と、下側中間部 144と、 上側小径ランド 145と、上側中間部 146と、大径ランド 147と、報知部 122と、軸部 12 3を、上記の順で、上方に向かって連設することで、構成されている。上側'下側小径 ランド 145, 143は同径とされて、下端部 117、上側 ·下側中間部 146, 144、軸部 1 23よりも大径とされ、報知部 122はこれらよりも大径とされ、大径ランド 147が最も大 径とされている。上側 ·下側小径ランド 145， 143は小径部 141内に摺動自在に備え られ、又、大径ランド 147は大径部 142内に摺動自在に備えられており、大径ランド 1 47と上側小径ランド 145間の距離が、スプール 2の接続位置と遮断位置間の距離よ りも大とされている。これにより、スプール孔 10の内面における、上側小径ランド 145 の摺動区域が外気による汚染から防護されて、薬液の汚染の惧れが少なくされてい る。尚、大径ランド 147は、実施例 1のストツバ部兼用とされている。 FIG. 25 to FIG. 27 show a ninth embodiment of the present invention, in which the spool hole 10 of the housing 1 has a lower small-diameter portion 141 and an upper side where the diameter is larger than the small-diameter portion 141. Consisting of a large diameter part 142 of The spool 2 has a lower end portion 117, a lower small-diameter land 143, a lower intermediate portion 144, an upper small-diameter land 145, an upper intermediate portion 146, a large-diameter land 147, a notification portion 122, and a shaft portion. 12 3 are connected in an upward direction in the above order. The upper and lower lands 145 and 143 have the same diameter, and have a larger diameter than the lower end 117, the upper and lower intermediate portions 146 and 144, and the shaft 123, and the notification unit 122 has a larger diameter than these. The large diameter land 147 is the largest diameter. The upper and lower small lands 145, 143 are slidably provided in the small diameter portion 141, and the large lands 147 are slidably provided in the large diameter portion 142. The distance between the upper small-diameter lands 145 is larger than the distance between the connection position and the blocking position of the spool 2. Accordingly, the sliding area of the upper small-diameter land 145 on the inner surface of the spool hole 10 is protected from contamination by the outside air, and the possibility of contamination of the chemical solution is reduced. Incidentally, the large-diameter land 147 is also used as the stopper portion of the first embodiment.
[0092] 上記構成例では、血管が確保されている力 \否力、を確認する際において、梃子 13 1の基部に下向きの操作力を作用させた場合には、大径ランド 147の下面にも負圧 が作用するので、その分、スプール 2を上方に摺動させるための操作力が大となり、 施術者自身が、梃子 131を操作していることを確実に認識できる。 [0092] In the above configuration example, when a downward operation force is applied to the base of the lever 131 when checking the force of securing the blood vessel, the force on the lower surface of the large-diameter land 147 Since the negative pressure acts on the spool 2, the operating force for sliding the spool 2 upward is increased by that amount, and the operator himself can surely recognize that the lever 131 is being operated.
実施例 10  Example 10
[0093] 図 28は本発明の第 10実施例を示すもので、スプール 2が、上側中間部 146と大径 ランド 147間で分離されて、下側構成体 149と、上側構成体 150から成る。  FIG. 28 shows a tenth embodiment of the present invention, in which a spool 2 is divided between an upper intermediate portion 146 and a large-diameter land 147, and is composed of a lower component 149 and an upper component 150. .
[0094] 上記構成例では、血管が確保されている場合等の通常時には、上側構成体 150の 上昇時には、下側構成体 149との間で作用する負圧により、下側構成体 149が上昇 し、又、上側構成体 150の下降時には、その押圧により、下側構成体 149が下降す る。又、血管が確保されているカ 否力、を確認する際において、梃子 131の基部に下 向きの操作力を作用させた場合には、上側構成体 150の大径ランド 147の下端面に 作用する負圧が、「下側構成体 149の下端面に作用する負圧に両下端面の面積比『 (大径ランド 147の下端面の面積) Z (スプール 2の下端部 117及び下側小径ランド 1 43の両者の下端面の面積）、又は、（大径ランド 147の最大横断面積) Z (下側小径 ランド 143の最大横断面積)』を乗じた大きな圧力」となるため、その分、スプール 2を 上方に摺動させるための操作力が第 9実施例の場合よりも大となり、施術者自身が、 梃子 131を操作していることを第 9実施例の場合よりも更により確実に認識できる。 実施例 11 [0095] 図 29— 33は、本発明の第 11実施例を示すもので、ハウジング 1は透明なプラスチ ック製とされ、第 1 ·第 2部材 203, 204と、蓋体 205を有する。 [0094] In the above configuration example, in a normal state such as when a blood vessel is secured, when the upper component 150 rises, the lower component 149 rises due to the negative pressure acting between the lower component 149 and the lower component 149. When the upper component 150 is lowered, the lower component 149 is lowered by the pressing. Also, when a downward operation force is applied to the base of the lever 131 when confirming the force of securing the blood vessel, the force acts on the lower end surface of the large-diameter land 147 of the upper structure 150. The negative pressure acting on the lower end surface of the lower component 149 is equal to the area ratio of both lower end surfaces ((the area of the lower end surface of the large diameter land 147) Z (the lower end portion 117 of the spool 2 and the lower small diameter). Large area multiplied by the area of the lower end surfaces of both the land 143) or (the maximum cross-sectional area of the large-diameter land 147) Z (the maximum cross-sectional area of the lower small-diameter land 143) ”. The operating force for sliding the spool 2 upward is larger than in the case of the ninth embodiment, and the operator himself can operate the lever 131 more reliably than in the case of the ninth embodiment. I can recognize. Example 11 FIGS. 29-33 show an eleventh embodiment of the present invention. The housing 1 is made of transparent plastic, and has first and second members 203 and 204 and a lid 205.
[0096] 図 31—図 33に示すように、第 1部材 203は、軸心方向（前後方向）後方に開口す る有底円筒状とされて、その先端部が、スプール 2の先端部と対向する対向部 211と されると共に、その内部が、軸心方向のスプール孔 210とされている。第 1部材 203 の先端部側の側壁部には、流出ポート 213が半径方向に貫通形成され、該ポート 21 3はスプール孔 210と連通している。  As shown in FIG. 31-FIG. 33, the first member 203 has a bottomed cylindrical shape that opens rearward in the axial direction (front-rear direction), and its distal end is in contact with the distal end of the spool 2. An opposing portion 211 is formed, and the inside thereof is formed as a spool hole 210 in the axial direction. An outflow port 213 is formed in a side wall portion on the tip end side of the first member 203 in a radial direction, and the port 213 communicates with the spool hole 210.
[0097] 第 2部材 204は、軸心方向両方に開口する略円筒状とされて、基部側の接続部 21 4と、接続部 214よりも小径とされた先端部側の注射ライン装着部 209を有し、一体成 形されている。接続部 214は、第 1部材 203に先端側から外嵌固着されて、流出ポー ト 213が接続部 214に内有されると共に、流出ポート 213が、第 1 ·第 2部材 203, 20 4の間隙 215を介して、注射ライン装着部 209と連通している。  [0097] The second member 204 has a substantially cylindrical shape that opens in both axial directions, and has a connecting portion 214 on the base side and an injection line mounting portion 209 on the distal end side smaller in diameter than the connecting portion 214. And are integrally formed. The connection portion 214 is externally fitted and fixed to the first member 203 from the distal end side, and the outflow port 213 is included in the connection portion 214, and the outflow port 213 is connected to the first and second members 203 and 204. It communicates with the injection line mounting part 209 via the gap 215.
[0098] 蓋体 205は、スプール 2の軸心方向後方側への摺動を規制するもので、第 1部材 2 03の基端部に外嵌固着されると共に、その中央部には、開口部 217が上下方向に 貫通形成され、その内周部が、第 1部材 203よりも径方向内方に突出している。  [0098] The lid 205 restricts sliding of the spool 2 toward the rear side in the axial center direction. The lid 205 is externally fitted and fixed to the base end of the first member 203, and has an opening at the center thereof. The portion 217 is formed to penetrate in the up-down direction, and its inner peripheral portion projects radially inward from the first member 203.
[0099] スプール 2はスプール孔 210に軸心方向後方から挿入されて、スプール孔 210に 軸心方向に摺動自在に備えられ、スプール 2の先端部が第 1部材 203の対向部 211 に当接する接続位置（図 29及び図 31参照）と、後述する遮断位置（図 30及び図 33 参照）に位置変更自在とされている。スプーノレ 2はベース部 219と、ベース部 219の 先端部に備えられるシール用部材 222を有し、スプール 2の先端部と第 1部材 203の 対向部 211間が、作動用流入部 221とされている。  [0099] The spool 2 is inserted into the spool hole 210 from the rear in the axial direction, and is slidably provided in the spool hole 210 in the axial direction. The tip of the spool 2 contacts the opposing portion 211 of the first member 203. The position can be freely changed between a contacting position (see FIGS. 29 and 31) and a blocking position (see FIGS. 30 and 33) described later. The spoonlet 2 has a base portion 219 and a sealing member 222 provided at a distal end portion of the base portion 219. An operation inflow portion 221 is provided between the distal end portion of the spool 2 and the facing portion 211 of the first member 203. I have.
[0100] ベース部 219は、スプール 2の大部分を構成するもので、略円筒形状とされて、貫 通孔 224が軸心方向に形成されている。この貫通孔 224の先端部は連通路 225とさ れ、この連通路 225の先端力 作動用流入部 221と常時連通する作動ポート 226と されている。ベース部 219の軸心方向中途部には、径方向外方に突出し且つ蓋体 2 05よりも軸心方向前方に位置する当接部 229が形成され、図 33に示すように、この 当接部 229が蓋体 205の前面に当接した位置力 S、スプール 2の遮断位置とされてい る。ベース部 219の基部はチップ装着部 208とされて、蓋体 205から軸心方向後方 に大きく突出している。チップ装着部 208には、薬液供給手段に備えられたルァロッ クアダプターと螺合するフランジ 227が備えられている。 [0100] The base portion 219 constitutes most of the spool 2, is substantially cylindrical, and has a through hole 224 formed in the axial direction. The distal end of the through hole 224 is formed as a communication passage 225, and is formed as an operation port 226 which is always in communication with the distal end force inflow portion 221 of the communication passage 225. A contact portion 229 projecting radially outward and located in front of the lid 205 in the axial direction is formed at an intermediate portion in the axial direction of the base portion 219. As shown in FIG. The portion 229 is in a position force S in contact with the front surface of the lid 205, and is in a blocking position of the spool 2. The base of the base part 219 is a tip mounting part 208, and is axially rearward from the lid 205. It protrudes greatly. The tip mounting section 208 is provided with a flange 227 that is screwed with a luer adapter provided in the chemical liquid supply means.
[0101] チップ装着部の先端部（又は、上記先端部及びその近傍部分）の外周面には、報 知部 220が形成されている。この報知部 220は、スプール 2が接続位置にある時には 、ハウジング 1内部に位置し、スプール 2が遮断位置にある時には、ハウジング 1から 軸心方向後方に突出する。  [0101] A notification unit 220 is formed on the outer peripheral surface of the tip portion (or the tip portion and its vicinity) of the tip mounting portion. The notification unit 220 is located inside the housing 1 when the spool 2 is at the connection position, and protrudes axially rearward from the housing 1 when the spool 2 is at the blocking position.
[0102] シール用部材 222は、ベース部 219の先端部に弾性変形を介して外嵌固定されて 、スプール孔 210に内装されるもので、このシール用部材 222及びベース部 219の 先端部の側壁部には、連通路 225及びスプール孔 210と連通すると共にスプール 2 の摺動により流出ポート 213と断続自在に接続される流入ポート 212が半径方向に 貫通形成されている。シール用部材 222の外周部には、第 1一第 4ランド 241— 244 が、先端部から基端部に向かって、軸心方向に並設されて、これらの外周部が、シー ル部として、スプール孔 210の内面に軸心方向に摺動自在に液密状態（気密状態） で当接 (圧接)している。尚、上記当接により、スプール 2は任意の摺動位置で保持可 能とされており、スプールの摺動に必要な外力（摺動開始外力、設定外力）以上の大 きさの外力がスプール 2に軸心方向に作用した際に、スプール 2が摺動可能とされて いる。即ち、上記ランド 241— 244の外周のシール部は、上記摺動開始外力を定め る設定手段としての機能も有している。これらシール部は、通常、各ランド 241— 244 と一体形成されるが、別体とされたシール部材により構成される場合もある。そして、 第 1 ·第 2ランド 241 , 242間は、流入ポート 212と流出ポート 213の接続の遮断時に 流出ポート 213と連通する遮断用グループ 245とされている。又、第 2 ·第 3ランド 242 , 243間は接続用グループ 246とされている。このグループ 246は、流入ポート 212 と、常時、連通すると共に、流入ポート 212と流出ポート 213の接続時にのみ、流出 ポート 213と連通する。更に、第 3 ·第 4ランド 243, 244間の距離は、スプール 2の接 続位置と遮断位置間の距離よりも大とされている。  [0102] The sealing member 222 is externally fitted and fixed to the distal end portion of the base portion 219 via elastic deformation, and is housed in the spool hole 210. The sealing member 222 and the distal end portion of the base portion 219 An inflow port 212 that communicates with the communication passage 225 and the spool hole 210 and that is connected to the outflow port 213 intermittently by sliding of the spool 2 is formed through the side wall in the radial direction. On the outer peripheral portion of the sealing member 222, first to fourth lands 241 to 244 are arranged in the axial direction from the distal end portion to the proximal end portion, and these outer peripheral portions serve as a seal portion. In addition, the inner surface of the spool hole 210 is slidably (pressed) in the liquid-tight state (air-tight state) so as to be slidable in the axial direction. The contact makes it possible to hold the spool 2 at an arbitrary sliding position, and an external force greater than the external force required for sliding the spool (sliding start external force, set external force) is applied. When acting on the shaft 2 in the axial direction, the spool 2 is slidable. That is, the seal portion on the outer periphery of the lands 241 to 244 also has a function as a setting means for determining the external force for starting the sliding. These seal portions are usually formed integrally with the lands 241 to 244, but may be constituted by separate seal members. The first and second lands 241 and 242 form a blocking group 245 that communicates with the outflow port 213 when the connection between the inflow port 212 and the outflow port 213 is cut off. A connection group 246 is provided between the second and third lands 242, 243. The group 246 always communicates with the inflow port 212 and communicates with the outflow port 213 only when the inflow port 212 and the outflow port 213 are connected. Further, the distance between the third and fourth lands 243, 244 is larger than the distance between the connection position of the spool 2 and the blocking position.
[0103] ところで、上記連通路 225と作動用流入部 221が良好に連通するように、ベース部 219の先端面が、軸心方向後方に向かって、若干テーパー状とされたテーパー面 2 47とされてレヽる。そして、連通路 225、又は、貫通孔 224及び連通路 225により、薬 液供給停止手段が構成されるが、この薬液供給停止手段に、作動用流入部 221を 含めることもある。 [0103] By the way, the distal end surface of the base portion 219 has a tapered surface 247 which is slightly tapered toward the rear in the axial center direction so that the communication passage 225 and the inflow portion 221 for operation can communicate well. Being done. Then, the communication passage 225 or the through-hole 224 and the communication passage 225 Although a liquid supply stopping means is configured, the chemical liquid supply stopping means may include an inflow portion 221 for operation.
[0104] 上記構成例では、注射時には、注射ライン装着部 209に、シリンジのチップに装着 可能な注射針、既に血管に留置された留置針、或いは、カテーテル力 延びる注射 ラインが装着され、一方、チップ装着部 208に、薬液供給手段として、薬液が充填さ れたシリンジのチップが装着される。又、スプール 2は図 29及び図 31に示す接続位 置にあって、その接続用グノレーブ 36により、流入ポート 212と流出ポート 213が接続 されている。  [0104] In the above configuration example, at the time of injection, an injection needle attachable to the tip of a syringe, an indwelling needle already indwelled in a blood vessel, or an injection line extending the catheter force is attached to the injection line attachment portion 209. A tip of a syringe filled with a drug solution is mounted on the tip mounting section 208 as a drug solution supply means. The spool 2 is at the connection position shown in FIGS. 29 and 31, and the inflow port 212 and the outflow port 213 are connected by the connection gnoreve 36.
[0105] 注射前には、まず、シリンジのプランジャーを押圧して、患者までの流路、即ち、貫 通孔 224、作動用流入部 221、流入ポート 212、接続用グループ 246、流出ポート 2 13、第 1 ·第 2部材 204の間隙 215、注射ライン装着部 209及び注射ライン内部に薬 液を充填して、上記内部の空気を除去する所謂「プライミング」を行なった後、注射ラ インの注射針を患者の血管に穿刺する。尚、上記プライミングを生理食塩水により行 なう場合もある。  [0105] Before injection, first, the plunger of the syringe is depressed so that the flow path to the patient, that is, the through hole 224, the working inflow portion 221, the inflow port 212, the connection group 246, and the outflow port 2 13. After filling the gap 215 between the first and second members 204, the injection line mounting part 209 and the inside of the injection line with a drug solution to remove the air inside the so-called "priming", The injection needle is punctured into the patient's blood vessel. The priming may be performed using a physiological saline solution.
[0106] 次に、シリンジのプランジャーを押圧するが、この際、血管が確保、即ち、確実に、 注射ラインの注射針が血管に穿刺されて、注射ラインが血管に接続されていると共に 、薬液の注入速度が正規注入速度である場合には、下記のように、スプール 2が接 続位置に保持されるので、薬液が血管内に流入し、通常通りの注射を行なえる。  [0106] Next, the plunger of the syringe is pressed. At this time, the blood vessel is secured, that is, the injection needle of the injection line is punctured into the blood vessel, and the injection line is connected to the blood vessel. When the injection speed of the drug solution is the normal injection speed, the spool 2 is held at the connection position as described below, so that the drug solution flows into the blood vessel and the injection can be performed as usual.
[0107] 即ち、薬液の圧力が、連通路 225から作動用流入部 221内に作用することにより、 薬液の設定注入圧力以下の通常注入圧力、つまり、注射時における、シリンジの針 のゲージや、シリンジの断面積等に起因する薬液の通常の圧力上昇、例えば、シリン ジのプランジャーの摺動初期における薬液の圧力上昇や、薬液の正規注入速度等 による薬液の圧力上昇によって、スプール 2の先端面に対して、軸心方向後方への 外力が作用する。しかし、この外力よりもスプール 2の摺動開始外力が大とされている ので、スプール 2が不慮に摺動する惧れはなぐ上記のように、通常通りの注射を行 なえる。  [0107] That is, the pressure of the medicinal solution acts from the communication passage 225 into the inflow portion 221 for operation, so that the normal injecting pressure equal to or lower than the set injecting pressure of the medicinal solution, that is, the gauge of the needle of the syringe at the time of injection, The normal pressure increase of the chemical due to the cross-sectional area of the syringe, etc., for example, the pressure increase of the chemical at the initial stage of sliding of the plunger of the syringe, and the pressure increase of the chemical due to the regular injection speed of the chemical, etc. An external force acts axially rearward on the surface. However, since the external force at which the spool 2 starts sliding is larger than this external force, there is no danger of the spool 2 sliding unexpectedly. As described above, injection can be performed as usual.
[0108] しかし、注射時の初期に、血管が確保されていない場合、即ち、注射ラインの注射 針が血管に穿刺されておらず、注射ラインが血管に接続されていない場合には、薬 液の設定注入圧力以上の大きな異常注入圧力が、連通路 225及び作動用流入部 2 21を介して、スプール 2の先端面に作用し、スプール 2に作用する軸心方向後方へ の外力が摺動開始外力以上となる。 However, when blood vessels are not secured at the beginning of the injection, that is, when the injection needle of the injection line is not punctured by the blood vessel and the injection line is not connected to the blood vessel, A large abnormal injection pressure equal to or higher than the set injection pressure of the liquid acts on the distal end surface of the spool 2 via the communication passage 225 and the inflow portion 221 for operation, and the external force acting on the spool 2 in the axial rearward direction is slid. It becomes more than the external force at the start of movement.
[0109] これにより、スプール 2が軸心方向後方へ摺動すると共に、シリンジの薬液力 連通 路 225を介して、作動用流入部 221内に流入し続ける。これにより、スプール 2が図 3 0及び図 33に示す遮断位置となって、当接部 229が蓋体 205に当接し、流出ポート 213が遮断用グループ 245と連通して、流入ポート 212と流出ポート 213の接続が遮 断され、報知部 220がハウジング 1から軸心方向後方に突出する。  As a result, the spool 2 slides rearward in the axial direction, and continues to flow into the working inflow portion 221 via the chemical liquid communication passage 225 of the syringe. As a result, the spool 2 comes to the blocking position shown in FIGS. 30 and 33, the contact portion 229 contacts the lid 205, the outflow port 213 communicates with the blocking group 245, and the outflow port 213 flows out of the inflow port 212. The connection of the port 213 is interrupted, and the notification unit 220 projects from the housing 1 rearward in the axial center.
[0110] これにより、シリンジのプランジャーを押圧できなくなり、薬液が必要部位でない箇 所に無理に注入されないため、患者が著しい痛みを感じることもなレ、。換言すれば、 患者は必要な医療をスムーズに受け入れることが可能になると共に、薬液の血管外 への漏出に伴う治療行為等の追加的な医療行為も防止できるため、医療経済的にも 効率を向上できることが期待される。  [0110] As a result, the plunger of the syringe cannot be pressed, and the drug solution is not forcibly injected into a portion that is not a necessary portion, so that the patient may not feel significant pain. In other words, the patient can smoothly receive the required medical treatment, and can prevent additional medical treatment such as treatment due to leakage of the drug solution out of the blood vessel. It is expected that it can be improved.
[0111] 又、上記のように、シリンジのプランジャーを押圧できなくなるので、施術者は、上記 の異常、即ち、血管が確保されていないことを容易に手元側で知ることができるが、 更に、報知部 220がハウジング 1から突出するので、施術者は容易にこれを視認でき 、これによつても、血管が確保されていないことを容易に手元側で知ることができる。  [0111] Further, as described above, since it becomes impossible to press the plunger of the syringe, the practitioner can easily know the above-mentioned abnormality, that is, that the blood vessel is not secured, at the hand side. Since the notification unit 220 protrudes from the housing 1, the practitioner can easily visually recognize the notification unit, and also can easily know at hand that the blood vessel is not secured.
[0112] この際、シリンジのプランジャーを引けば、チップ装着部 208内等の薬液をシリンジ 内に戻すこともでき、この面でも、薬液が無駄にならないようにでき、医療コストの増大 を防止できる。尚、シリンジのプランジャーを引いた際には、作動用流入部 221内の 薬液の圧力が低下して、スプール 2が接続位置に戻ることもあるが、戻らない場合に は、手でスプール 2を軸心方向前方に押圧して、スプール 2を接続位置に戻せばよ レ、。このとき、注射ラインの一部を手指等により閉塞させた後、前記操作を行なえば、 作動用流入部 221内の薬液も再びシリンジ内に戻すことができる。  [0112] At this time, by pulling the plunger of the syringe, the drug solution in the tip mounting portion 208 and the like can be returned into the syringe. In this aspect, the drug solution can be prevented from being wasted, thereby preventing an increase in medical costs. it can. In addition, when the plunger of the syringe is pulled, the pressure of the chemical in the inflow portion 221 for operation may decrease, and the spool 2 may return to the connection position. By pressing the spool forward in the axial direction to return the spool 2 to the connection position. At this time, if the above operation is performed after a part of the injection line is closed by a finger or the like, the drug solution in the operation inflow portion 221 can be returned to the syringe again.
[0113] 上記のような処理をした後、再度、上記一連の操作を最初から行ない、血管が確保 されていることを確認した後、注射を従来同様に行なう。  [0113] After the above-described processing, the above-described series of operations is performed again from the beginning, and after confirming that a blood vessel is secured, injection is performed in the same manner as in the related art.
[0114] 本構成例では、上記のように、血管が確保されていない場合には、薬液を投与でき ないので、薬液の投与直前に、シリンジのプランジャーを引いて、注射ラインに血液 が逆流してくる所謂「フラッシュバック」を目視で確認して、血管が確保されているか、 否力を確認する必要がない。 [0114] In the present configuration example, as described above, when a blood vessel is not secured, a drug solution cannot be administered. Therefore, immediately before administration of the drug solution, the plunger of the syringe is pulled and the blood is injected into the injection line. There is no need to visually check the so-called “flashback” when the blood flows backward to check whether blood vessels are secured or not.
[0115] 従って、「CT検査や MRI検査等で患者が装置内部にいて、薬液を血管内に高速 に注入する必要があるような場合」や、「薬液の投与を行なうシリンジが、投与前にプ ランジャーを引くことができない場合が多い薬液充填済みシリンジ (プレフィルドシリン ジ）の場合」や、「患者の奥深い部位に揷入されているカテーテルを介して、薬液の 投与を行なう場合」や、「放射線医薬品を投与する際には、施術者の被曝を防止する ために、シリンジや注射ラインも防護壁で覆われている場合」でも、薬液が血管外へ 漏出するという不安なぐ各種検查ゃ治療を行える。  [0115] Therefore, "when a patient is inside the device during a CT or MRI examination and it is necessary to inject a drug solution into a blood vessel at a high speed", or "a syringe for administering a drug solution must In the case of a syringe filled with a drug solution (prefilled syringe) that often cannot pull the plunger, or in the case of administering a drug solution via a catheter inserted deep into the patient, or When administering radiopharmaceuticals, even if the syringe and injection line are covered with a protective wall to prevent exposure to the practitioner, even if the drug solution leaks out of the blood vessels, there is Can be performed.
[0116] 又、薬液の種類によっては、薬液の最大注入速度が定められたものがあるが、これ に対しても、下記のように、薬液が、正規注入速度よりも速い速度で注入されることは ない。即ち、注射の初期が過ぎた後に、薬液の注入速度が正規注入速度よりも速く なると、上記同様に、薬液の設定注入圧力以上の大きな異常注入圧力が、連通路 2 25及び作動用流入部 221を介して、スプール 2の先端面に作用し、スプール 2に作 用する軸心方向後方へのの外力が摺動開始外力以上となる。  [0116] In addition, depending on the type of the chemical solution, there is a case where the maximum injection speed of the chemical solution is determined. However, as described below, the chemical solution is injected at a speed higher than the normal injection speed. There is nothing. That is, if the injection speed of the drug solution becomes faster than the normal injection speed after the initial stage of the injection, as described above, a large abnormal injection pressure equal to or higher than the set injection pressure of the drug solution is generated by the communication passage 225 and the inflow portion 221 for operation. The external force acting on the distal end surface of the spool 2 through the shaft 2 and acting on the spool 2 in the axially rearward direction is equal to or greater than the external force at the start of sliding.
[0117] これにより、スプール 2が遮断位置となり、薬液の注入ができなくなるので、患者に 大きな負担が掛かることがないと共に、これを報知部 220が報知するので、施術者は 、薬液の注入速度が正規注入速度よりも速いことを、容易に手元側で知ることができ る。従って、施術者は、スプール 2を接続位置に戻した後、シリンジのプランジャーを 前よりも遅い速度で押圧し、薬液の注入速度を正規注入速度として、薬液を注入す ればよい。  [0117] As a result, the spool 2 is brought into the shut-off position, and it becomes impossible to inject the medicinal solution. Therefore, a large burden is not applied to the patient, and the notifying unit 220 informs the user of this. Can be easily found at hand. Therefore, after returning the spool 2 to the connection position, the practitioner presses the plunger of the syringe at a lower speed than before, and injects the medicinal solution at the normal injecting speed of the medicinal solution.
実施例 12  Example 12
[0118] 図 34は本発明の第 12実施例を示し、スプール 2の摺動に必要な外力の値を設定 する設定機構 (手段） 233が備えられて、下記のように構成されている。  FIG. 34 shows a twelfth embodiment of the present invention, which is provided with a setting mechanism (means) 233 for setting a value of an external force necessary for sliding of the spool 2, and is configured as follows.
[0119] 即ち、スプール 2のチップ装着部 208の先端部に、ベース部 219の基部よりも大径 とされた周突起 234がー体形成されている。  That is, a peripheral projection 234 having a larger diameter than the base of the base portion 219 is formed at the tip of the tip mounting portion 208 of the spool 2.
[0120] 又、ハウジング 1の第 1部材 203の基端部には、ベース部 219に外嵌された調整筒  [0120] In addition, the base end of the first member 203 of the housing 1 is provided with an adjusting cylinder externally fitted to the base 219.
235が外嵌、固定されている。調整筒 235は、弾性変形可能な材料により一体形成 されており、その先端部の外周面には、上方に向かってテーパー状とされたテーパ 一螺子部 236が形成されている。又、調整筒 235の内周面の軸心方向中途部には、 第 1部材 203よりも軸心方向後方に位置し且つ径方向内方に突出する周突起 237が 一体形成され、この周突起 237が、スプール 2の周突起 234の軸心方向後方に配設 されている。更に、調整筒 235の基端から周突起 234にわたる部分には、径方向に 貫通形成されたスリット（図示省略）が配設されている。調整筒 235の構成材料として は、スプール 2と同様なものが用いられる。 235 is externally fitted and fixed. Adjusting cylinder 235 is integrally formed of elastically deformable material A tapered single thread portion 236 tapered upward is formed on the outer peripheral surface of the distal end portion. A circumferential projection 237 that is located axially rearward of the first member 203 and protrudes inward in the radial direction is formed integrally with a halfway portion of the inner circumferential surface of the adjusting cylinder 235 in the axial direction. 237 is disposed axially rearward of the circumferential projection 234 of the spool 2. Further, a slit (not shown) penetrating in the radial direction is provided in a portion extending from the base end of the adjusting cylinder 235 to the peripheral projection 234. As the constituent material of the adjusting cylinder 235, the same material as that of the spool 2 is used.
[0121] 蓋体 205は調整筒 235に外嵌されて、その内周の雌螺子部 238がテーパー螺子 部 236に螺合されており、蓋体 205の調整筒 235に対する螺進退により、調整筒 23 5のスリットが周方向に拡縮して、周突起 237の内径が拡縮する。尚、周突起 237の 内径が最大径の場合でも、この内径よりも、周突起 234の外径が大となるようにされて いる。又、上記内径よりも、ベース部 219の当接部 229の外径が大となるようにされて 、周突起 237が当接部 229のストッパとなるようにされている。尚、調整筒 235に、テ 一パー螺子部 236ではなぐ通常の螺子部を形成し、蓋体 205にテーパー螺子部を 形成してもよい。 [0121] The cover 205 is externally fitted to the adjusting cylinder 235, and the female screw portion 238 on the inner periphery thereof is screwed to the tapered screw portion 236. The slits 235 expand and contract in the circumferential direction, and the inner diameter of the circumferential projection 237 expands and contracts. In addition, even when the inner diameter of the peripheral projection 237 is the maximum diameter, the outer diameter of the peripheral projection 234 is set to be larger than this inner diameter. Further, the outer diameter of the contact portion 229 of the base portion 219 is made larger than the inner diameter, so that the circumferential projection 237 serves as a stopper of the contact portion 229. The adjusting cylinder 235 may be formed with a normal screw portion that does not use the taper screw portion 236, and the lid 205 may be formed with a tapered screw portion.
[0122] 上記構成例では、スプール 2が、接続位置から遮断位置に移動する際には、調整 筒 235の周突起 237及び/又はスプール 2の周突起 234が弾性変形して、スプール 2の周突起 234が調整筒 235の周突起 237の内部を通過する必要がある。従って、 調整筒 235の周突起 237の内径を拡縮することにより、スプール 2の周突起 234が調 整筒 235の周突起 237の内部を通過するに必要な外力、即ち、摺動開始外力を自 由に設定できる。  In the above configuration example, when the spool 2 moves from the connection position to the shut-off position, the peripheral protrusion 237 of the adjusting cylinder 235 and / or the peripheral protrusion 234 of the spool 2 are elastically deformed, and the periphery of the spool 2 is deformed. The projection 234 needs to pass through the inside of the peripheral projection 237 of the adjustment cylinder 235. Therefore, by expanding and contracting the inner diameter of the circumferential projection 237 of the adjusting cylinder 235, the external force required for the circumferential projection 234 of the spool 2 to pass through the inside of the circumferential projection 237 of the adjusting cylinder 235, that is, the external force at which the sliding starts, is automatically increased. Can be set for any reason.
実施例 13  Example 13
[0123] 図 35—図 38は、本発明の第 13実施例を示し、ハウジング 1の第 2部材 204の接続 部 214が第 1部材 203の全体に外嵌されている。又、スプール 2のシール用部材 22 2の基部にベース部 219の先端部が弾性変形を介して嵌入されて、一体化され、ベ ース部 219及びシール用部材 222に貫通孔 224が形成されている。  FIG. 35 to FIG. 38 show a thirteenth embodiment of the present invention, in which the connecting portion 214 of the second member 204 of the housing 1 is fitted over the entire first member 203. Further, the distal end of the base part 219 is fitted into the base of the sealing member 222 of the spool 2 via elastic deformation and integrated, and a through hole 224 is formed in the base part 219 and the sealing member 222. ing.
[0124] 尚、上記実施例では、スプールの遮断位置から接続位置への復帰操作は、スプー ルの手動による操作、又は、シリンジのプランジャーを引く操作で行なった力 S、復帰を 短時間で自動的に行なうために、スプールを軸心方向前方に押圧するコイルパネや 圧縮空気パネ等の各種パネ、或いは、その他の復帰手段を備えてもよい。 In the above embodiment, the return operation of the spool from the shut-off position to the connection position is performed by manually operating the spool or by pulling the plunger of the syringe with the force S and the return. In order to automatically perform the operation in a short time, various panels such as a coil panel and a compressed air panel for pressing the spool forward in the axial direction, or other return means may be provided.
[0125] 又、本発明に係る薬液投与セットの一例としては、例えば、薬液投与セットが、薬液 供給手段である薬液充填済みシリンジと本発明に係る薬液供給制御装置を有するも のが挙げられる。この際には、 （1) シリンジに備えられたルアーロックアダプターと薬 液供給制御装置のチップ装着部のフランジを螺合することにより、シリンジと薬液供 給制御装置を接続する場合と、 (2) シリンジと薬液供給制御装置との間に注射ライ ンを接続して、薬液供給制御装置の注射ライン装着部に注射針を接続する場合と、 ( 3) 薬液供給制御装置と注射針との間に注射ラインを接続する場合がある。又、薬 液投与セットには、薬液供給手段と薬液供給制御装置に、更に、カテーテル、注射 針、留置針、三方活栓（三方活栓機能）、エクステンションチューブ、その他生体の血 管内に薬液を投与する際に使用される種々の医療器具或いはその機能を組み合わ せたものも含めることもできる。  [0125] Further, as an example of the drug solution administration set according to the present invention, for example, the drug solution administration set includes a syringe filled with a drug solution as a drug solution supply means and the drug solution supply control device according to the present invention. In this case, (1) the syringe is connected to the chemical liquid supply control device by screwing the luer lock adapter provided on the syringe with the flange of the tip mounting part of the chemical liquid supply control device; ) Connecting the injection line between the syringe and the drug supply control device and connecting the injection needle to the injection line mounting part of the drug solution supply control device; and (3) connecting the drug solution control device and the injection needle May be connected to an injection line. In the drug administration set, a drug solution is supplied to a drug solution supply means and a drug solution supply control device, and further into a catheter, an injection needle, an indwelling needle, a three-way cock (a three-way cock function), an extension tube, and other blood vessels of a living body. Various medical instruments used in such a case or a combination of functions thereof may be included.
産業上の利用可能性  Industrial applicability
[0126] 以上のように、本発明にかかる薬液供給制御方法、その方法に使用する薬液供給 制御装置及びその装置を用いた薬液投与セットは、患者に薬液を投与する方法、装 置及びセットとして有用である。 [0126] As described above, the drug solution supply control method according to the present invention, the drug solution supply control device used in the method, and the drug solution administration set using the device are provided as a method, a device, and a set for administering a drug solution to a patient. Useful.

Claims

請求の範囲 The scope of the claims
[1] (a) 薬液供給手段と注射ライン間に介装されたハウジングと、  [1] (a) a housing interposed between the drug solution supply means and the injection line,
(b) ハウジング内に軸心方向に摺動自在に備えられて、軸心方向の摺動により、 薬液供給手段と注射ラインを断続自在に接続するスプールと、  (b) a spool slidably provided in the housing in the axial direction so as to connect the drug supply means and the injection line intermittently by sliding in the axial direction;
(c) 薬液供給手段から注射ラインへの薬液の供給を停止させる薬液供給停止手 段及び/又は薬液供給手段から注射ラインへの薬液供給に関する不具合を報知す る不具合報知手段  (c) Means for stopping the supply of the drug solution from the drug solution supply means to the injection line and / or defect notification means for reporting a problem with the supply of the drug solution from the drug solution supply means to the injection line.
を使用し、  Use
注射ラインが閉鎖状態の場合に、薬液供給停止手段及び/又は不具合報知手段 を作動させる薬液供給制御方法。  A chemical supply control method for activating chemical supply stop means and / or failure notification means when an injection line is closed.
[2] ハウジングに、 [2] In the housing,
スプールの軸心方向一端面と対向し、この端面との間が作動用流入部とされる 対向部  Opposing portion that faces one end surface in the axial direction of the spool, and the space between the end surface and the end surface is an inflow portion for operation.
が形成されており、  Is formed,
薬液の圧力が設定圧力以上の場合に、薬液供給停止手段が、薬液供給手段又は 注射ラインの薬液を作動用流入部に供給して、スプールを軸心方向に摺動させ、こ れにより、薬液供給手段から注射ラインへの薬液の供給を停止させる請求項 1記載 の薬液供給制御方法。  When the pressure of the chemical solution is equal to or higher than the set pressure, the chemical solution supply stopping means supplies the chemical solution from the chemical solution supply means or the injection line to the inflow portion for operation, and slides the spool in the axial direction, thereby causing the chemical solution to stop. The chemical solution supply control method according to claim 1, wherein the supply of the chemical solution from the supply means to the injection line is stopped.
[3] (a) 薬液供給手段と注射ライン間に介装されたハウジングと、 [3] (a) a housing interposed between the drug solution supply means and the injection line;
(b) ハウジング内に軸心方向に摺動自在に備えられ、軸心方向の摺動により、薬 液供給手段と注射ラインを断続自在に接続するスプールと、  (b) a spool slidably provided in the housing in the axial direction so as to connect the drug supply means and the injection line intermittently by sliding in the axial direction;
(c) 薬液供給停止手段及び/又は不具合報知手段  (c) Chemical liquid supply stopping means and / or fault notification means
を有し、  Has,
薬液供給停止手段は、注射ラインが閉鎖状態の場合及び/又は薬液の圧力が設 定圧力以上の場合に薬液供給手段から注射ラインへの薬液の供給を停止させる手 段とされ、  The chemical supply stopping means is a means for stopping the supply of the chemical from the chemical supply means to the injection line when the injection line is in a closed state and / or when the pressure of the chemical is equal to or higher than a set pressure,
不具合報知手段は、薬液供給手段から注射ラインへの薬液供給に関する不具合を 報知する手段とされた薬液供給制御装置。 The malfunction notification means is a chemical liquid supply control device that is configured to notify a malfunction related to the supply of the chemical liquid from the chemical liquid supply means to the injection line.
[4] ハウジングに、 [4] In the housing,
スプールの軸心方向一端面と対向し、この端面との間が作動用流入部とされる 対向部  Opposing portion that faces one end surface in the axial direction of the spool, and the space between the end surface and the end surface is an inflow portion for operation.
が形成され、  Is formed,
薬液供給停止手段が、作動時に、薬液供給手段又は注射ラインの薬液を作動用 流入部に供給して、スプールを軸心方向に摺動させる請求項 3記載の薬液供給制御 装置。  4. The chemical liquid supply control device according to claim 3, wherein the chemical liquid supply stop means supplies the chemical liquid from the chemical liquid supply means or the injection line to the inflow portion for operation and slides the spool in the axial direction during operation.
[5] ハウジングに、  [5] In the housing,
(a) スプール孔と、  (a) a spool hole;
(b) 薬液供給手段からの薬液をスプール孔内に流入させる流入ポートと、 (b) an inflow port through which the chemical from the chemical supply means flows into the spool hole;
(c) スプール孔内の薬液を注射ラインに流出させる流出ポート (c) Outflow port that allows the drug solution in the spool hole to flow out to the injection line
が形成され、  Is formed,
スプール孔内に、流入ポートと流出ポートを断続自在に接続するスプールが軸心 方向に摺動自在に備えられ、  A spool for intermittently connecting the inflow port and the outflow port is provided in the spool hole so as to be slidable in the axial direction,
流入ポートと流出ポートの接続時において、薬液の圧力が上昇した際に、この圧力 により、スプールを摺動させて、流入ポートと流出ポートの接続を遮断する薬液供給 停止手段が備えられた請求項 4記載の薬液供給制御装置。  When the pressure of the chemical solution rises at the time of connection between the inflow port and the outflow port, there is provided a chemical solution supply stop means for sliding the spool by this pressure to cut off the connection between the inflow port and the outflow port. 4. The chemical supply control device according to 4.
[6] スプールが、軸心方向に離間した一対のランドを有し、 [6] the spool has a pair of lands separated in the axial direction,
両ランド間が、流入ポートと流出ポートを接続するグノレーブとされ、  A gnoreve connecting the inflow port and the outflow port between both lands,
薬液供給停止手段が、  Chemical liquid supply stopping means,
スプールに形成されて、グループと作動用流入部を連通させる流路 とされた請求項 5記載の薬液供給制御装置。  6. The chemical liquid supply control device according to claim 5, wherein the chemical liquid supply control device is formed in the spool and serves as a flow path for communicating the group with the inflow portion for operation.
[7] 薬液供給停止手段が、 [7] The chemical liquid supply stopping means,
ハウジングに形成されて、薬液供給手段と作動用流入部を連通させる入口側作 動ポート  An inlet-side operation port formed in the housing and communicating the chemical supply means with the inflow portion for operation.
とされた請求項 5記載の薬液供給制御装置。  6. The chemical liquid supply control device according to claim 5, wherein
[8] 流入ポートが、入口側作動ポートと兼用とされた請求項 7記載の薬液供給制御装置 [8] The chemical liquid supply control device according to claim 7, wherein the inflow port is also used as an inlet-side operation port.
[9] 薬液供給停止手段が、 [9] The chemical liquid supply stopping means
ノ、ウジングに形成されて、注射ラインと作動用流入部を連通させる出口側作動 ポート  No., outlet side operation port formed in the housing and communicating the injection line and the inflow part for operation
とされた請求項 5記載の薬液供給制御装置。  6. The chemical liquid supply control device according to claim 5, wherein
[10] 流出ポートが、出口側作動ポートと兼用とされた請求項 9記載の薬液供給制御装置 10. The chemical liquid supply control device according to claim 9, wherein the outflow port is also used as an outlet-side operation port.
[11] 対向部の少なくとも一部が、弾性材料からなる補助部とされた請求項 4一 10の何れ かに記載の薬液供給制御装置。 11. The chemical liquid supply control device according to claim 4, wherein at least a part of the facing part is an auxiliary part made of an elastic material.
[12] 薬液の圧力が設定圧力以上になった際にのみ、スプールの摺動を許容して、薬 液供給手段と注射ラインの接続を遮断する設定手段 [12] Setting means for permitting sliding of the spool and disconnecting the connection between the chemical supply means and the injection line only when the pressure of the chemical liquid becomes equal to or higher than the set pressure.
が備えられた請求項 4一 11の何れかに記載の薬液供給制御装置。  12. The chemical liquid supply control device according to claim 4, further comprising:
[13] 設定手段の設定圧力が調整可能とされた請求項 12記載の薬液供給制御装置。 13. The chemical liquid supply control device according to claim 12, wherein the set pressure of the setting means is adjustable.
[14] スプールに係脱自在に係合された操作手段を使用し、 [14] using operating means detachably engaged with the spool,
注射ラインに液体を満たした状態で、操作手段によりスプールに軸心方向の操作 力を作用させ、これにより、  With the injection line filled with liquid, the operating means applies an operating force in the axial direction to the spool, thereby
注射ラインが開放状態の場合には、スプールが摺動して、注射ライン内の液体がハ ウジング内に吸引され、  When the injection line is open, the spool slides and the liquid in the injection line is sucked into the housing,
注射ラインが閉鎖状態の場合には、スプールが摺動せず、スプールと操作手段の 係合が解除される請求項 1又は 2記載の薬液供給制御方法。  3. The chemical liquid supply control method according to claim 1, wherein when the injection line is in a closed state, the spool does not slide and the engagement between the spool and the operating means is released.
[15] 注射ラインが開放状態の場合に、注射ライン内の液体が、スプールにおける、操作 方向とは反対側の端面とハウジング間に吸引される請求項 14記載の薬液供給制御 方法。 15. The chemical liquid supply control method according to claim 14, wherein when the injection line is in an open state, the liquid in the injection line is sucked between the end surface of the spool on the side opposite to the operation direction and the housing.
[16] スプールの操作手段を有し、  [16] having spool operating means,
ハウジングが、  The housing is
(a) スプールが軸心方向に摺動自在に内装されたスプール孔と、  (a) a spool hole in which the spool is slidably mounted in the axial direction,
(b) 薬液供給手段からの薬液をスプール孔内に流入させる流入ポートと、 (b) an inflow port through which the chemical from the chemical supply means flows into the spool hole;
(c) スプールの摺動により、流入ポートと断続自在に接続されて、スプール孔内の 薬液を注射ラインに流出させる流出ポートと、 (d) 注射ラインの薬液を作動用流入部に流入させる作動ポート (c) an outflow port which is connected to the inflow port intermittently by sliding the spool, and which allows the liquid medicine in the spool hole to flow out to the injection line; (d) An operation port that allows the liquid medicine in the injection line to flow into the operation inflow section
を有し、  Has,
スプールと操作手段間に、  Between the spool and the operating means,
両者を係脱自在に係合し、スプールを対向部から離間する方向に操作した際に おいて、操作手段の操作力が設定操作力以上になった場合に、上記係合を解除す る係合手段  When the operating force of the operating means is greater than or equal to the set operating force when the two are detachably engaged and the spool is operated in a direction away from the opposing portion, the engagement is released. Means
が備えられた請求項 4記載の薬液供給制御装置。  5. The chemical liquid supply control device according to claim 4, further comprising:
[17] スプールが、軸心方向に離間し且つスプール孔内に軸心方向に摺動自在に備え られる一対のランドを有し、 [17] The spool has a pair of lands spaced apart in the axial direction and slidably provided in the spool hole in the axial direction,
両ランド間が、流入ポートと流出ポートを接続するグノレーブとされた請求項 16記載 の薬液供給制御装置。  17. The chemical liquid supply control device according to claim 16, wherein the land is a gnorebe connecting the inflow port and the outflow port.
[18] スプールが、 [18] The spool
(a) 軸心方向に離間して、スプール孔内に軸心方向に摺動自在に備えられた一 対の小径ランドと、  (a) a pair of small-diameter lands provided in the spool hole so as to be slidable in the axial direction, spaced apart in the axial direction;
(b) 両小径ランドとスプールの軸心方向他端面間に配設されると共に、小径ランド よりも大径とされて、スプール孔内に軸心方向に摺動自在に備えられる大径ランド を有する請求項 16記載の薬液供給制御装置。  (b) A large-diameter land which is disposed between both small-diameter lands and the other end surface in the axial direction of the spool, has a larger diameter than the small-diameter land, and is provided slidably in the axial direction in the spool hole. 17. The chemical liquid supply control device according to claim 16, comprising:
[19] 両小径ランドと大径ランドが別体とされた請求項 18記載の薬液供給制御装置。 19. The chemical liquid supply control device according to claim 18, wherein both the small-diameter land and the large-diameter land are formed separately.
[20] スプールに、 [20] On the spool,
薬液供給手段と注射ラインの接続の遮断時に、ハウジングの外部に突出して、 上記遮断を報知する報知部  A notifying unit that projects outside the housing when the connection between the drug solution supply unit and the injection line is cut off, and notifies the shutoff.
が備えられた請求項 3— 13、 16 19の何れかに記載の薬液供給制御装置。  20. The chemical liquid supply control device according to claim 3, further comprising:
[21] 操作手段が、 [21] The operation means,
(a) ハウジングに揺動自在に枢支された梃子と、  (a) a lever pivotably supported by the housing,
(b) 揺動後の梃子を原位置に復帰させる復帰パネ  (b) A return panel that returns the lever after swinging to its original position
を有し、  Has,
係合手段が、  The engagement means is
(i) スプールに形成された周溝と、 (ii)梃子に形成され、周溝に弾性変形を介して係脱自在に係合する係合部 を有する請求項 16— 20の何れかに記載の薬液供給制御装置。 (i) a circumferential groove formed in the spool; (ii) The chemical liquid supply control device according to any one of claims 16 to 20, further comprising an engagement portion formed on the lever and engaged with the circumferential groove so as to be removably engaged via elastic deformation.
[22] 梃子が、 [22] Leverage,
流入ポートと流出ポートの接続の遮断時に、この遮断を報知する報知部 とされた請求項 21記載の薬液供給制御装置。  22. The chemical liquid supply control device according to claim 21, wherein when the connection between the inflow port and the outflow port is cut off, the notification unit notifies the cutoff.
[23] ハウジングに、流出ポートを囲繞する筒状の注射ライン装着部が備えられ、 [23] The housing is provided with a cylindrical injection line mounting portion surrounding the outflow port,
注射ライン装着部に、注射ラインと接続されるルアーロックアダプターが備えられた 請求項 5— 13、 16 22の何れかに記載の薬液供給制御装置。  The drug solution supply control device according to any one of claims 5 to 13, 16 and 22, wherein the injection line mounting portion is provided with a luer lock adapter connected to the injection line.
[24] ハウジングが、 [24] The housing is
(a) 軸心方向に形成され、内部にスプールが軸心方向に摺動自在に備えられる スプール孔と、  (a) a spool hole formed in the axial direction, in which the spool is slidably provided in the axial direction,
(b) ハウジングの側部に形成され、スプール孔と連通すると共に、注射ラインと接 続される流出ポート  (b) Outflow port formed on the side of the housing, communicating with the spool hole and connected to the injection line
を有し、  Has,
スプールが、  The spool is
(i) 薬液供給手段と接続されると共に、作動用流入部と連通する連通路と、 (i) a communication passage connected to the chemical liquid supply means and communicating with the inflow portion for operation;
(ii)スプールの側部に形成され、連通路及びスプール孔と連通すると共に、スプー ルの摺動により、流出ポートと断続自在に接続される流入ポート (ii) An inflow port formed on the side of the spool, communicating with the communication passage and the spool hole, and connected to the outflow port intermittently by sliding of the spool.
を有する請求項 4記載の薬液供給制御装置。  5. The chemical liquid supply control device according to claim 4, comprising:
[25] ハウジングが、 [25] The housing
(a) 略筒状とされ、内部がスプール孔とされて、先端部が対向部とされると共に、 側壁部に流入ポートが半径方向に形成された第 1部材と、  (a) a first member having a substantially cylindrical shape, the inside being a spool hole, the leading end being an opposing portion, and an inflow port being formed in a side wall portion in a radial direction;
(b) 軸心方向両方に開口する略筒状とされ、基部側の接続部と、注射ラインと接 続される先端部側の注射ライン装着部を有する第 2部材  (b) A second member which is substantially cylindrical and opens in both axial directions and has a connection portion on the base side and an injection line mounting portion on the distal end portion connected to the injection line.
を有し、  Has,
接続部が第 1部材に先端側から外嵌固着されて、流入ポートが接続部に内有され ると共に、流入ポートが、第 1 ·第 2部材の間隙を介して、注射ライン装着部と連通す る請求項 24記載の薬液供給制御装置。 The connecting portion is externally fitted and fixed to the first member from the distal end side, and the inflow port is included in the connecting portion, and the inflow port communicates with the injection line mounting portion via the gap between the first and second members. 25. The chemical liquid supply control device according to claim 24, wherein the chemical liquid supply control device is passed through.
[26] 注射ライン装着部に、注射ラインと接続されるルアーロックアダプターが備えられた 請求項 24又は 25記載の薬液供給制御装置。 26. The drug solution supply control device according to claim 24 or 25, wherein the injection line mounting portion is provided with a luer lock adapter connected to the injection line.
[27] ハウジングが、 [27] The housing
第 1部材の基端部に備えられ、スプールの軸心方向後方側への摺動を規制す る蓋体を有する請求項 25又は 26記載の薬液供給制御装置。  27. The chemical liquid supply control device according to claim 25, further comprising a lid provided at a base end portion of the first member, the lid body restricting sliding of the spool rearward in the axial direction.
[28] スプールの外周部に、第 1一第 3ランドが、先端部から基端部に向かって、軸心方 向に並設され、 [28] On the outer peripheral portion of the spool, first to third lands are juxtaposed in the axial direction from the distal end portion to the proximal end portion,
第 1 ·第 2ランド間が、  Between the first and second lands,
流入ポートと流出ポートの接続の遮断時に、流出ポートと連通する遮断用ダル ーブとされ、  When the connection between the inflow port and the outflow port is cut off, it is a shutoff valve that communicates with the outflow port,
第 2 ·第 3ランド間が、  Between the 2nd and 3rd land,
流入ポートと、常時、連通すると共に、流入ポートと流出ポートの接続時に、流出 ポートと連通する接続用グループ  A connection group that is always in communication with the inflow port and communicates with the outflow port when the inflow port and outflow port are connected.
とされた請求項 24— 27の何れかに記載の薬液供給制御装置。  28. The chemical liquid supply control device according to claim 24, wherein:
[29] スプールの外周部における、第 3ランドよりも基部側に、第 4ランドが備えられ、 第 3 ·第 4ランド間の距離が、スプールの接続位置と遮断位置間の距離よりも大とさ れた請求項 28記載の薬液供給制御装置。 [29] A fourth land is provided on the outer peripheral portion of the spool closer to the base side than the third land, and the distance between the third and fourth lands is larger than the distance between the connection position and the shutoff position of the spool. 29. The chemical liquid supply control device according to claim 28, wherein:
[30] スプールに貫通孔が軸心方向に形成されて、 [30] A through hole is formed in the spool in the axial direction,
スプールの基部が、シリンジのチップが分離可能に装着されるチップ装着部とされ ると共に、  The base of the spool serves as a tip mounting section where the tip of the syringe is detachably mounted, and
貫通孔の先端部が連通路とされた請求項 24— 29の何れかに記載の薬液供給制 御装置。  30. The chemical liquid supply control device according to claim 24, wherein a distal end of the through hole is a communication passage.
[31] スプールの摺動に必要な外力の値を設定する設定手段が備えられた請求項 24— [31] A setting means for setting a value of an external force necessary for sliding of the spool is provided.
30の何れかに記載の薬液供給制御装置。 30. The drug solution supply control device according to any one of items 30.
[32] 設定手段の設定値が調整可能とされた請求項 31記載の薬液供給制御装置。 32. The chemical liquid supply control device according to claim 31, wherein a setting value of the setting means is adjustable.
[33] スプールに、 [33] On the spool,
流入ポートと流出ポートの接続の遮断時に、ハウジングの軸心方向後方に突出 して、上記遮断を報知する報知部 が備えられた請求項 24— 32の何れかに記載の薬液供給制御装置。 When the connection between the inflow port and the outflow port is interrupted, a notification section that projects rearward in the axial direction of the housing and notifies the above-mentioned interruption. 33. The chemical liquid supply control device according to claim 24, further comprising:
[34] 薬液供給手段と流入ポートとの間に、三方活栓機能が備えられた請求項 5— 13、 1[34] The claim 5-13, 1 wherein a three-way cock is provided between the chemical solution supply means and the inflow port.
6— 33の何れかに記載の薬液供給制御装置。 34. The chemical liquid supply control device according to any one of 6-33.
[35] 請求項 3— 13、 16 34の何れかに記載の薬液供給制御装置と薬液供給手段を 有する薬液投与セット。 [35] A chemical solution administration set comprising the chemical solution supply control device according to any one of claims 3-13 and 1634 and a chemical solution supply means.
[36] 薬液供給手段が注射用シリンジである請求項 35記載の薬液投与セット。 36. The drug solution administration set according to claim 35, wherein the drug solution supply means is a syringe for injection.
[37] 注射用シリンジが薬液充填済みシリンジである請求項 36記載の薬液投与セット。 37. The drug solution administration set according to claim 36, wherein the syringe for injection is a syringe filled with a drug solution.
[38] 薬液供給手段が点滴用バッグである請求項 35記載の薬液投与セット。 38. The drug solution administration set according to claim 35, wherein the drug solution supply means is an infusion bag.
[39] 点滴用バッグが薬液充填済みバッグである請求項 38記載の薬液投与セット。 39. The drug solution administration set according to claim 38, wherein the infusion bag is a bag filled with a drug solution.
[40] 薬液供給手段により供給される薬液が造影剤である請求項 35 39の何れかに記 載の薬液投与セット。 40. The drug solution administration set according to claim 35, wherein the drug solution supplied by the drug solution supply means is a contrast agent.
[41] 造影剤が MRI造影剤である請求項 40記載の薬液投与セット。 41. The drug solution administration set according to claim 40, wherein the contrast agent is an MRI contrast agent.
PCT/JP2004/007503 2003-06-02 2004-06-01 Chemical liquid supply control method, chemical liquid supply control device used for the method, and chemical liquid dosing set using the device WO2004108192A1 (en)

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