WO2004108089A3 - A micro granulate formulation for oral administration in aqueous suspension - Google Patents

A micro granulate formulation for oral administration in aqueous suspension Download PDF

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Publication number
WO2004108089A3
WO2004108089A3 PCT/US2004/017862 US2004017862W WO2004108089A3 WO 2004108089 A3 WO2004108089 A3 WO 2004108089A3 US 2004017862 W US2004017862 W US 2004017862W WO 2004108089 A3 WO2004108089 A3 WO 2004108089A3
Authority
WO
WIPO (PCT)
Prior art keywords
oral administration
formulation
aqueous suspension
granulate formulation
micro granulate
Prior art date
Application number
PCT/US2004/017862
Other languages
French (fr)
Other versions
WO2004108089A2 (en
Inventor
Esposito Julio Cesar Rodriguez
Erausquin Gabriel A De
Original Assignee
Esposito Julio Cesar Rodriguez
Erausquin Gabriel A De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esposito Julio Cesar Rodriguez, Erausquin Gabriel A De filed Critical Esposito Julio Cesar Rodriguez
Publication of WO2004108089A2 publication Critical patent/WO2004108089A2/en
Publication of WO2004108089A3 publication Critical patent/WO2004108089A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Abstract

A micro granulate formulation for oral administration in an aqueous suspension, the formulation comprising granules having a multi-layer structure with a central core for carrying an active ingredient and a taste masking outer layer capable of supporting dilution in the aqueous solution but rapidly diluting in the gastrointestinal environment. The invention also provides a method for obtaining the formulation and a pharmaceutical composition.
PCT/US2004/017862 2003-06-06 2004-06-07 A micro granulate formulation for oral administration in aqueous suspension WO2004108089A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ARP030102011 2003-06-06
ARP030102011 AR040157A1 (en) 2003-06-06 2003-06-06 A FORMULATION IN MICROGRANULES FOR ORAL ADMINISTRATION IN WATERPROOF SUSPENSION

Publications (2)

Publication Number Publication Date
WO2004108089A2 WO2004108089A2 (en) 2004-12-16
WO2004108089A3 true WO2004108089A3 (en) 2005-03-24

Family

ID=33494452

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/017862 WO2004108089A2 (en) 2003-06-06 2004-06-07 A micro granulate formulation for oral administration in aqueous suspension

Country Status (2)

Country Link
AR (1) AR040157A1 (en)
WO (1) WO2004108089A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101340733B1 (en) * 2012-12-31 2013-12-12 (주) 에프엔지리서치 Novel microgranule preparations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214386B1 (en) * 1995-11-22 2001-04-10 Recordati, S.A. Prompt-release oral pharmaceutical compositions for extemporaneous suspensions
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
US20040013741A1 (en) * 2002-07-15 2004-01-22 Meisel Gerard M. Gastrointestinal compositions
US20040052847A1 (en) * 2001-08-20 2004-03-18 Namburi Ranga R. Oral dosage forms of water insoluble drugs and methods of making the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214386B1 (en) * 1995-11-22 2001-04-10 Recordati, S.A. Prompt-release oral pharmaceutical compositions for extemporaneous suspensions
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
US20040052847A1 (en) * 2001-08-20 2004-03-18 Namburi Ranga R. Oral dosage forms of water insoluble drugs and methods of making the same
US20040013741A1 (en) * 2002-07-15 2004-01-22 Meisel Gerard M. Gastrointestinal compositions

Also Published As

Publication number Publication date
WO2004108089A2 (en) 2004-12-16
AR040157A1 (en) 2005-03-16

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