WO2004105686A3 - Novel topical steroid cream formulations - Google Patents

Novel topical steroid cream formulations Download PDF

Info

Publication number
WO2004105686A3
WO2004105686A3 PCT/US2004/015698 US2004015698W WO2004105686A3 WO 2004105686 A3 WO2004105686 A3 WO 2004105686A3 US 2004015698 W US2004015698 W US 2004015698W WO 2004105686 A3 WO2004105686 A3 WO 2004105686A3
Authority
WO
WIPO (PCT)
Prior art keywords
cream formulations
topical steroid
novel topical
steroid cream
novel
Prior art date
Application number
PCT/US2004/015698
Other languages
French (fr)
Other versions
WO2004105686A2 (en
Inventor
Maxine G Moldenhaur
Original Assignee
Taro Pharmaceuticals Usa Inc
Maxine G Moldenhaur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharmaceuticals Usa Inc, Maxine G Moldenhaur filed Critical Taro Pharmaceuticals Usa Inc
Priority to CA002532707A priority Critical patent/CA2532707A1/en
Priority to EP04752675A priority patent/EP1624861A2/en
Publication of WO2004105686A2 publication Critical patent/WO2004105686A2/en
Publication of WO2004105686A3 publication Critical patent/WO2004105686A3/en
Priority to IL172118A priority patent/IL172118A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Disclosed is a novel mometasone furoate cream formulation for topical administration in a oleaginous base containing propylene glycol. This cream is a cosmetically elegant preparation of mometasone that is both stable and bioeffective.
PCT/US2004/015698 2003-05-23 2004-05-19 Novel topical steroid cream formulations WO2004105686A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002532707A CA2532707A1 (en) 2003-05-23 2004-05-19 Novel topical steroid cream formulations
EP04752675A EP1624861A2 (en) 2003-05-23 2004-05-19 Novel topical steroid cream formulations
IL172118A IL172118A0 (en) 2003-05-23 2005-11-22 Novel topical steroid cream formulations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47331303P 2003-05-23 2003-05-23
US60/473,313 2003-05-23

Publications (2)

Publication Number Publication Date
WO2004105686A2 WO2004105686A2 (en) 2004-12-09
WO2004105686A3 true WO2004105686A3 (en) 2005-09-22

Family

ID=33490587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/015698 WO2004105686A2 (en) 2003-05-23 2004-05-19 Novel topical steroid cream formulations

Country Status (5)

Country Link
US (1) US7312207B2 (en)
EP (1) EP1624861A2 (en)
CA (1) CA2532707A1 (en)
IL (1) IL172118A0 (en)
WO (1) WO2004105686A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006034883A1 (en) * 2006-07-25 2008-01-31 Hermal Kurt Herrmann Gmbh & Co. Ohg Composition, useful to treat inflammatory skin disease, e.g. psoriasis, comprises mometasone furoate, water, a combination of aromatic alcohol and a solvent e.g. alkoxylated fatty-alcohol and/or aliphatic alcohol, and further additives
US8728497B2 (en) * 2009-05-12 2014-05-20 Galenica Ab Oil-in-water emulsion of mometasone and propylene glycol
EP2394653A1 (en) 2010-05-26 2011-12-14 Almirall, S.A. Topical pharmaceutical compositions comprising mometasone furoate
CN112402366A (en) * 2020-11-12 2021-02-26 广州白云山医药集团股份有限公司白云山何济公制药厂 Mometasone furoate cream and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696105A (en) * 1996-03-14 1997-12-09 Hackler; Walter A. Antifungal nail composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808610A (en) 1986-10-02 1989-02-28 Schering Corporation Mometasone furoate anti-inflammatory cream composition using hexylene glycol
US4775529A (en) 1987-05-21 1988-10-04 Schering Corporation Steroid lotion
US5422361A (en) 1989-12-20 1995-06-06 Schering Corporation Stable cream and lotion bases for lipophilic drug compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696105A (en) * 1996-03-14 1997-12-09 Hackler; Walter A. Antifungal nail composition

Also Published As

Publication number Publication date
EP1624861A2 (en) 2006-02-15
IL172118A0 (en) 2009-02-11
CA2532707A1 (en) 2004-12-09
US7312207B2 (en) 2007-12-25
WO2004105686A2 (en) 2004-12-09
US20040248866A1 (en) 2004-12-09

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