WO2004101820A3 - Use of sah gene as a marker for psoriasis - Google Patents

Use of sah gene as a marker for psoriasis Download PDF

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Publication number
WO2004101820A3
WO2004101820A3 PCT/FR2004/001064 FR2004001064W WO2004101820A3 WO 2004101820 A3 WO2004101820 A3 WO 2004101820A3 FR 2004001064 W FR2004001064 W FR 2004001064W WO 2004101820 A3 WO2004101820 A3 WO 2004101820A3
Authority
WO
WIPO (PCT)
Prior art keywords
psoriasis
marker
sah gene
sah
gene
Prior art date
Application number
PCT/FR2004/001064
Other languages
French (fr)
Other versions
WO2004101820A2 (en
Inventor
Valerie Trinquet
Patricia Rossio
Michel Demarchez
Original Assignee
Galderma Res & Dev
Valerie Trinquet
Patricia Rossio
Michel Demarchez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev, Valerie Trinquet, Patricia Rossio, Michel Demarchez filed Critical Galderma Res & Dev
Publication of WO2004101820A2 publication Critical patent/WO2004101820A2/en
Publication of WO2004101820A3 publication Critical patent/WO2004101820A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a probe relating to the SAH gene for characterization of a biological sample. The invention also relates to the use of said probe in order to identify an compound for the treatment of psoriasis, an identification method and a novel search tool.
PCT/FR2004/001064 2003-05-07 2004-05-03 Use of sah gene as a marker for psoriasis WO2004101820A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0305571A FR2854639A1 (en) 2003-05-07 2003-05-07 Use of polynucleotide probe specific for the SAH gene in diagnosis of psoriasis and to screen for antipsoriatic agents, also therapeutic use by inhibiting SAH expression or activity
FR03/05571 2003-05-07

Publications (2)

Publication Number Publication Date
WO2004101820A2 WO2004101820A2 (en) 2004-11-25
WO2004101820A3 true WO2004101820A3 (en) 2005-01-20

Family

ID=33306221

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/001064 WO2004101820A2 (en) 2003-05-07 2004-05-03 Use of sah gene as a marker for psoriasis

Country Status (2)

Country Link
FR (1) FR2854639A1 (en)
WO (1) WO2004101820A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0955382A2 (en) * 1998-05-07 1999-11-10 Affymetrix, Inc. (a California Corporation) Polymorphisms associated with hypertension
WO2002044201A2 (en) * 2000-12-01 2002-06-06 Genaissance Pharmaceuticals, Inc. Haplotypes of the sah gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0955382A2 (en) * 1998-05-07 1999-11-10 Affymetrix, Inc. (a California Corporation) Polymorphisms associated with hypertension
WO2002044201A2 (en) * 2000-12-01 2002-06-06 Genaissance Pharmaceuticals, Inc. Haplotypes of the sah gene

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOWCOCK A M ET AL: "Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 10, no. 17, 15 August 2001 (2001-08-15), pages 1793 - 1805, XP002265788, ISSN: 0964-6906 *
DATABASE EMBL EBI; 28 October 2004 (2004-10-28), XP002304965, Database accession no. NM_005622 *
IWAI NAOHARU ET AL: "Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension", CIRCULATION, AMERICAN HEART ASSOCIATION, DALLAS, TX, US, vol. 105, no. 1, 1 January 2002 (2002-01-01), pages 41 - 47, XP001105333, ISSN: 0009-7322 *
NABIKA T ET AL: "Evaluation of the SA locus in human hypertension", HYPERTENSION, vol. 25, no. 1, 1995, pages 6 - 13, XP001104818, ISSN: 0194-911X *
OESTREICHER J L ET AL: "Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling", PHARMACOGENOMICS JOURNAL, NATURE PUBLISHING GROUP, GB, vol. 1, no. 4, 2001, pages 272 - 287, XP008036398, ISSN: 1470-269X *
PRADET-BALADE B ET AL: "Translation control: bridging the gap between genomics and proteomics?", TIBS TRENDS IN BIOCHEMICAL SCIENCES, ELSEVIER PUBLICATION, CAMBRIDGE, EN, vol. 26, no. 4, 1 April 2001 (2001-04-01), pages 225 - 229, XP004233580, ISSN: 0968-0004 *
ZHOU XIANGHONG ET AL: "Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array.", PHYSIOLOGICAL GENOMICS. 18 MAR 2003, vol. 13, no. 1, 18 March 2003 (2003-03-18), pages 69 - 78, XP002304964, ISSN: 1531-2267 *

Also Published As

Publication number Publication date
WO2004101820A2 (en) 2004-11-25
FR2854639A1 (en) 2004-11-12

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