WO2004100861A3 - Pharmaceutical composition comprising lectin - Google Patents

Pharmaceutical composition comprising lectin Download PDF

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Publication number
WO2004100861A3
WO2004100861A3 PCT/BR2004/000070 BR2004000070W WO2004100861A3 WO 2004100861 A3 WO2004100861 A3 WO 2004100861A3 BR 2004000070 W BR2004000070 W BR 2004000070W WO 2004100861 A3 WO2004100861 A3 WO 2004100861A3
Authority
WO
WIPO (PCT)
Prior art keywords
lectin
pharmaceutical composition
heal
plant
prevent
Prior art date
Application number
PCT/BR2004/000070
Other languages
French (fr)
Other versions
WO2004100861A2 (en
Inventor
Da Silva Luis Lamberti Pinto
Castelo Ademilson Panunto
Souza Goldman Maria Helena De
Antunes Barreira Maria C Roque
Oliveira Ricardo Santos De
Baruffi Marcelo Dias
De Molfetta Machado Jea Blanco
Original Assignee
Fundacao De Amparo A Pesquisa
Univ Sao Paulo
Da Silva Luis Lamberti Pinto
Castelo Ademilson Panunto
Souza Goldman Maria Helena De
Antunes Barreira Maria C Roque
Oliveira Ricardo Santos De
Baruffi Marcelo Dias
De Molfetta Machado Jea Blanco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao De Amparo A Pesquisa, Univ Sao Paulo, Da Silva Luis Lamberti Pinto, Castelo Ademilson Panunto, Souza Goldman Maria Helena De, Antunes Barreira Maria C Roque, Oliveira Ricardo Santos De, Baruffi Marcelo Dias, De Molfetta Machado Jea Blanco filed Critical Fundacao De Amparo A Pesquisa
Priority to EP04733749A priority Critical patent/EP1635891A2/en
Priority to JP2006529469A priority patent/JP2007528869A/en
Publication of WO2004100861A2 publication Critical patent/WO2004100861A2/en
Publication of WO2004100861A3 publication Critical patent/WO2004100861A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention deals with a pharmaceutical composition comprising lectin KM+ to prevent and heal epithelial wounds. The invention also comprises the use of lectin KM+, obtained from the plant Artocarpus integrifolia or the use of recombinant lectin to prepare medicaments.
PCT/BR2004/000070 2003-05-19 2004-05-19 Pharmaceutical composition comprising lectin WO2004100861A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04733749A EP1635891A2 (en) 2003-05-19 2004-05-19 Pharmaceutical composition to prevent and treat epithelial wounds, immunomodulating pharmaceutical composition, pharmaceutical composition, insecticide, insecticide composition, insecticide use of lectin km+ to treat cicatrizations, use of lectin km+ to prepare immunomodulating medicament
JP2006529469A JP2007528869A (en) 2003-05-19 2004-05-19 Pharmaceutical composition for epithelial wound prevention and treatment, immunoregulatory pharmaceutical composition, pharmaceutical composition, insecticide, insecticide composition, use of insecticide of lectin KM + in the treatment of scarring, use of lectin KM + in preparation of immunoregulatory drug , Use of lectin KM + in formulating antibacterial drugs, use of lectin KM + in formulating antiviral drugs, use of lectin KM + in formulating antifungal drugs, use of lectin KM + in formulating antiparasitic drugs, expression methods, DNA vectors, recombinant organisms , Nucleotide sequences, antibodies, proteins and extranuclear genes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRC10301547-5A BR0301547C1 (en) 2003-05-19 2003-05-19 pharmaceutical composition for treating fungal pathology comprising km + lectin, pharmaceutical composition for preventing fungal pathology comprising km + lectin, use of km + lectin for preparing medicine for treating fungal pathology, use of km + lectin for preparing medicine for preventing fungal pathology
BRPI0301547-5 2003-05-19

Publications (2)

Publication Number Publication Date
WO2004100861A2 WO2004100861A2 (en) 2004-11-25
WO2004100861A3 true WO2004100861A3 (en) 2006-12-07

Family

ID=37744501

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2004/000070 WO2004100861A2 (en) 2003-05-19 2004-05-19 Pharmaceutical composition comprising lectin

Country Status (5)

Country Link
EP (1) EP1635891A2 (en)
JP (1) JP2007528869A (en)
AR (1) AR044389A1 (en)
BR (1) BR0301547C1 (en)
WO (1) WO2004100861A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914858B1 (en) * 2007-04-13 2012-09-21 Lucas Meyer Cosmetics COSMETIC COMPOSITION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020001600A1 (en) * 1995-05-30 2002-01-03 Michael J. Oldham Method of using lectins for prevention and treatment of skin diseases and disorders

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, vol. 29, no. 8, pages 977 - 985 *
DATABASE MEDLINE [online] MORAES SM ET AL: "Purification, physicochemical characterization and biological properties of a lectin from Erythrina velutina forma aurantiaca seeds", XP003004899, Database accession no. NLM9181078 *
DATABASE MEDLINE [online] SANTOS- DE OLIVIERA R ET AL: "A neutrophil migration inducing lectin from Artocarpus integrifolia", XP003004898, Database accession no. NLM8046246 *
JOURNAL OF IMMUNOLOGY, vol. 153, no. 4, 1994, pages 1798 - 1807 *
ROSA J.C. ET AL.: "KM+, a mannose-binding lectin from Artocarpus integrifolia: Amino acid sequence, predicted tertiary structure, carbohydrate recognition, and analysis of the beta-prism fold", PROTEIN SCIENCE, vol. 8, 1999, pages 13 - 24, XP003005454 *

Also Published As

Publication number Publication date
EP1635891A2 (en) 2006-03-22
AR044389A1 (en) 2005-09-07
BR0301547A (en) 2005-03-22
BR0301547C1 (en) 2007-02-21
WO2004100861A2 (en) 2004-11-25
JP2007528869A (en) 2007-10-18

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