WO2004100860A3 - Stable liposomes for microencapsulation of animal venoms - Google Patents

Stable liposomes for microencapsulation of animal venoms Download PDF

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Publication number
WO2004100860A3
WO2004100860A3 PCT/BR2004/000067 BR2004000067W WO2004100860A3 WO 2004100860 A3 WO2004100860 A3 WO 2004100860A3 BR 2004000067 W BR2004000067 W BR 2004000067W WO 2004100860 A3 WO2004100860 A3 WO 2004100860A3
Authority
WO
WIPO (PCT)
Prior art keywords
microencapsulation
stable liposomes
animals
invention refers
present
Prior art date
Application number
PCT/BR2004/000067
Other languages
French (fr)
Other versions
WO2004100860A2 (en
Inventor
Maria Helena B Da Costa
Rosalvo Guidolin
Pedro Soares De Araujo
Gregory Gregoriadis
Reto Albert Schwendener
Original Assignee
Fundacao De Amparo A Pesquisa
Maria Helena B Da Costa
Rosalvo Guidolin
Pedro Soares De Araujo
Gregory Gregoriadis
Reto Albert Schwendener
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao De Amparo A Pesquisa, Maria Helena B Da Costa, Rosalvo Guidolin, Pedro Soares De Araujo, Gregory Gregoriadis, Reto Albert Schwendener filed Critical Fundacao De Amparo A Pesquisa
Publication of WO2004100860A2 publication Critical patent/WO2004100860A2/en
Publication of WO2004100860A3 publication Critical patent/WO2004100860A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A61K31/055—Phenols the aromatic ring being substituted by halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/583—Snakes; Lizards, e.g. chameleons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention refers to the microencapsulation of substances in stable liposomes of natural phospholipids for obtaining hyperimmune serum as the result of a formulation with less toxicity and increased immnunogenicity. More particularly, the present invention refers to stabilized liposomes containing poisons of animals, its process of obtainment and uses thereof for obtaining hyperimmune sera used in the treatment of accidents involving venom animals bites.
PCT/BR2004/000067 2003-05-16 2004-05-14 Stable liposomes for microencapsulation of animal venoms WO2004100860A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR0301513-0 2003-05-16
BR0301513A BR0301513A (en) 2003-05-16 2003-05-16 Liposomes, liposome formulations, their uses and processes for obtaining them, process for the production of hyperimmune serum, and method of prophylactic or curative treatment of diseases or disorders that may be treated by the administration of hyperimmune serum.

Publications (2)

Publication Number Publication Date
WO2004100860A2 WO2004100860A2 (en) 2004-11-25
WO2004100860A3 true WO2004100860A3 (en) 2008-02-28

Family

ID=39106338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2004/000067 WO2004100860A2 (en) 2003-05-16 2004-05-14 Stable liposomes for microencapsulation of animal venoms

Country Status (2)

Country Link
BR (1) BR0301513A (en)
WO (1) WO2004100860A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315349A1 (en) * 1987-10-23 1989-05-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Phospholipase A2 inhibiting compositions and their use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315349A1 (en) * 1987-10-23 1989-05-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Phospholipase A2 inhibiting compositions and their use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EVANS J. ET AL.: "Neutralization of edema, hemorrhage and myonecrosis induced by North American Crotalid venoms in simulated first-aid treatment", TOXICON, vol. 37, 1999, pages 633 - 650 *

Also Published As

Publication number Publication date
BR0301513A (en) 2005-03-15
WO2004100860A2 (en) 2004-11-25

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