WO2004098522A3 - Gemini vitamin d3 compounds and methods of use thereof - Google Patents

Gemini vitamin d3 compounds and methods of use thereof Download PDF

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Publication number
WO2004098522A3
WO2004098522A3 PCT/US2004/013703 US2004013703W WO2004098522A3 WO 2004098522 A3 WO2004098522 A3 WO 2004098522A3 US 2004013703 W US2004013703 W US 2004013703W WO 2004098522 A3 WO2004098522 A3 WO 2004098522A3
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WO
WIPO (PCT)
Prior art keywords
compounds
methods
vitamin
gemini vitamin
gemini
Prior art date
Application number
PCT/US2004/013703
Other languages
French (fr)
Other versions
WO2004098522A2 (en
Inventor
Luciano Adorini
Guiseppe Penna
Milan R Uskokovic
Hubert Maehr
Original Assignee
Bioxell Spa
Luciano Adorini
Guiseppe Penna
Milan R Uskokovic
Hubert Maehr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioxell Spa, Luciano Adorini, Guiseppe Penna, Milan R Uskokovic, Hubert Maehr filed Critical Bioxell Spa
Priority to AU2004235775A priority Critical patent/AU2004235775A1/en
Priority to JP2006514246A priority patent/JP2006525367A/en
Priority to CA002524026A priority patent/CA2524026A1/en
Priority to EP04751195A priority patent/EP1622455A4/en
Publication of WO2004098522A2 publication Critical patent/WO2004098522A2/en
Publication of WO2004098522A3 publication Critical patent/WO2004098522A3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The invention provides Gemini vitamin D3 compounds, methods for using the compounds to treat vitamin D3 associated states and pharmaceutical compositions containing the compounds.
PCT/US2004/013703 2003-04-30 2004-04-30 Gemini vitamin d3 compounds and methods of use thereof WO2004098522A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2004235775A AU2004235775A1 (en) 2003-04-30 2004-04-30 Gemini vitamin D3 compounds and methods of use thereof
JP2006514246A JP2006525367A (en) 2003-04-30 2004-04-30 Gemini vitamin D3 compound and method of use thereof
CA002524026A CA2524026A1 (en) 2003-04-30 2004-04-30 Gemini vitamin d3 compounds and methods of use thereof
EP04751195A EP1622455A4 (en) 2003-04-30 2004-04-30 Gemini vitamin d3 compounds and methods of use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46663803P 2003-04-30 2003-04-30
US60/466,638 2003-04-30

Publications (2)

Publication Number Publication Date
WO2004098522A2 WO2004098522A2 (en) 2004-11-18
WO2004098522A3 true WO2004098522A3 (en) 2005-02-03

Family

ID=33434966

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/013703 WO2004098522A2 (en) 2003-04-30 2004-04-30 Gemini vitamin d3 compounds and methods of use thereof

Country Status (5)

Country Link
EP (1) EP1622455A4 (en)
JP (1) JP2006525367A (en)
AU (1) AU2004235775A1 (en)
CA (1) CA2524026A1 (en)
WO (1) WO2004098522A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192255A1 (en) * 2003-07-30 2005-09-01 Jin Tian Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
BRPI0414701A (en) * 2003-09-24 2006-11-14 Bioxell Spa use of a vitamin d compound, method of prevention or treatment of bladder dysfunction in a patient, vitamin d compound e, kit
EP1830826A2 (en) * 2004-12-02 2007-09-12 Abbott Laboratories Use of a compound that activates a vitamin d receptor for reducing intimal hyperplasia, smooth muscle cell proliferation and restenosis in mammals
EP1879596A4 (en) * 2005-03-23 2009-01-21 Bioxell Spa 20-alkyl, gemini vitamin d3 compounds and methods of use thereof
US20090298799A1 (en) * 2005-03-23 2009-12-03 Bioxell S.P.A. Methods of Treating Osteoporosis and Secondary Hyperparathyroidism Using 20-Methyl, Gemini Vitamin D3 Compounds
US7286295B1 (en) 2005-11-30 2007-10-23 Sandia Corporation Microoptical compound lens
CA2664049A1 (en) * 2006-09-22 2008-03-27 Bioxell Spa Novel method
EP2148683A4 (en) * 2007-04-25 2012-09-12 Proventiv Therapeutics Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
CA2749967A1 (en) * 2009-01-16 2010-07-22 Pharmaceutical Compounding Nz Limited Medicament for the treatment of pain and inflammation
CN104758300A (en) * 2014-01-02 2015-07-08 上海泽生科技开发有限公司 Antibacterial applications of vitamin D and vitamin D composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049138A2 (en) * 1997-04-28 1998-11-05 F.Hoffmann-La Roche Ag Vitamin d3 analogs with bis c-20 side chains
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
US6030962A (en) * 1997-04-28 2000-02-29 Synttex (U.S.A.) Inc. Vitamin D3 analogs with bis C-20 side chains

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU744471B2 (en) * 1997-05-16 2002-02-21 Women & Infants Hospital 3-epi vitamin D2 compounds and uses thereof
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US20030095937A1 (en) * 2001-10-02 2003-05-22 Koeffler H. Philip Method for stimulating hair growth by administering vitamin D analogs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049138A2 (en) * 1997-04-28 1998-11-05 F.Hoffmann-La Roche Ag Vitamin d3 analogs with bis c-20 side chains
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
US6030962A (en) * 1997-04-28 2000-02-29 Synttex (U.S.A.) Inc. Vitamin D3 analogs with bis C-20 side chains

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1622455A4 *

Also Published As

Publication number Publication date
AU2004235775A1 (en) 2004-11-18
EP1622455A4 (en) 2009-12-16
CA2524026A1 (en) 2004-11-18
JP2006525367A (en) 2006-11-09
EP1622455A2 (en) 2006-02-08
WO2004098522A2 (en) 2004-11-18

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