WO2004097370A3 - Systemes et procedes de suivi d'activites chimiques et biologiques a l'aide de mesures differentielles - Google Patents

Systemes et procedes de suivi d'activites chimiques et biologiques a l'aide de mesures differentielles Download PDF

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Publication number
WO2004097370A3
WO2004097370A3 PCT/US2004/012614 US2004012614W WO2004097370A3 WO 2004097370 A3 WO2004097370 A3 WO 2004097370A3 US 2004012614 W US2004012614 W US 2004012614W WO 2004097370 A3 WO2004097370 A3 WO 2004097370A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
measurement
biolgical
activities
systems
Prior art date
Application number
PCT/US2004/012614
Other languages
English (en)
Other versions
WO2004097370A2 (fr
Inventor
John J Hefti
Dean M Drako
Original Assignee
Prometheus Biosciences Inc
John J Hefti
Dean M Drako
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2003/013181 external-priority patent/WO2003091732A2/fr
Application filed by Prometheus Biosciences Inc, John J Hefti, Dean M Drako filed Critical Prometheus Biosciences Inc
Priority to EP04750558A priority Critical patent/EP1623211A4/fr
Publication of WO2004097370A2 publication Critical patent/WO2004097370A2/fr
Publication of WO2004097370A3 publication Critical patent/WO2004097370A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D1/00—Measuring arrangements giving results other than momentary value of variable, of general application
    • G01D1/16—Measuring arrangements giving results other than momentary value of variable, of general application giving a value which is a function of two or more values, e.g. product or ratio
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B23/00—Testing or monitoring of control systems or parts thereof
    • G05B23/02—Electric testing or monitoring
    • G05B23/0205—Electric testing or monitoring by means of a monitoring system capable of detecting and responding to faults
    • G05B23/0218—Electric testing or monitoring by means of a monitoring system capable of detecting and responding to faults characterised by the fault detection method dealing with either existing or incipient faults
    • G05B23/0224—Process history based detection method, e.g. whereby history implies the availability of large amounts of data
    • G05B23/0227—Qualitative history assessment, whereby the type of data acted upon, e.g. waveforms, images or patterns, is not relevant, e.g. rule based assessment; if-then decisions
    • G05B23/0237—Qualitative history assessment, whereby the type of data acted upon, e.g. waveforms, images or patterns, is not relevant, e.g. rule based assessment; if-then decisions based on parallel systems, e.g. comparing signals produced at the same time by same type systems and detect faulty ones by noticing differences among their responses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00191—Control algorithm
    • B01J2219/00193—Sensing a parameter
    • B01J2219/00195—Sensing a parameter of the reaction system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00191—Control algorithm
    • B01J2219/00211—Control algorithm comparing a sensed parameter with a pre-set value
    • B01J2219/0022—Control algorithm comparing a sensed parameter with a pre-set value calculating difference
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00191—Control algorithm
    • B01J2219/00222—Control algorithm taking actions
    • B01J2219/00227—Control algorithm taking actions modifying the operating conditions
    • B01J2219/00229—Control algorithm taking actions modifying the operating conditions of the reaction system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

L'invention porte sur un système de suivi d'activités bio/chimiques comportant une première sonde de mesure, une deuxième sonde de mesure et un comparateur. La première sonde de mesure est conçue pour déterminer une ou plusieurs des propriétés d'un échantillon en un premier emplacement de l'échantillon et produire en réponse un premier signal de mesure; la deuxième sonde de mesure est conçue pour déterminer une ou plusieurs des propriétés d'un échantillon en un deuxième emplacement de l'échantillon et produire en réponse un deuxième signal de mesure. Le comparateur, reçoit les deux signaux de mesure et émet un signal exprimant leur différence qui correspond à la différence entre une ou plusieurs des activités bio/chimiques se produisant d'une part au premier emplacement de l'échantillon, et d'autre part au deuxième.
PCT/US2004/012614 2003-04-25 2004-04-23 Systemes et procedes de suivi d'activites chimiques et biologiques a l'aide de mesures differentielles WO2004097370A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04750558A EP1623211A4 (fr) 2003-04-25 2004-04-23 Systemes et procedes de suivi d'activites chimiques et biologiques a l'aide de mesures differentielles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US2003/013181 WO2003091732A2 (fr) 2002-04-26 2003-04-25 Procede base sur la diffusion et systeme pour detecter et surveiller l'activite d'especes biologiques et chimiques
USPCT/US03/13181 2003-04-25
US10/799,000 US7713477B2 (en) 2002-04-26 2004-03-11 Systems and methods for monitoring chemical and biological activities using differential measurements
US10/799,000 2004-03-11

Publications (2)

Publication Number Publication Date
WO2004097370A2 WO2004097370A2 (fr) 2004-11-11
WO2004097370A3 true WO2004097370A3 (fr) 2005-03-24

Family

ID=33422364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/012614 WO2004097370A2 (fr) 2003-04-25 2004-04-23 Systemes et procedes de suivi d'activites chimiques et biologiques a l'aide de mesures differentielles

Country Status (2)

Country Link
EP (1) EP1623211A4 (fr)
WO (1) WO2004097370A2 (fr)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941563A (en) * 1974-04-23 1976-03-02 E. I. Du Pont De Nemours & Company Method and apparatus for detecting hexavalent chromium
US3999047A (en) * 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US5192507A (en) * 1987-06-05 1993-03-09 Arthur D. Little, Inc. Receptor-based biosensors
US5554339A (en) * 1988-11-14 1996-09-10 I-Stat Corporation Process for the manufacture of wholly microfabricated biosensors
US5910286A (en) * 1995-02-21 1999-06-08 Thomson-Csf Highly selective chemical sensor
US6241950B1 (en) * 1998-02-13 2001-06-05 Airxpert Systems, Inc. Fluid sampling system
US6455000B1 (en) * 1999-07-12 2002-09-24 Fantom Technologies Inc. Method and apparatus for measuring the concentration of a gas
US6534012B1 (en) * 2000-08-02 2003-03-18 Sensys Medical, Inc. Apparatus and method for reproducibly modifying localized absorption and scattering coefficients at a tissue measurement site during optical sampling
US6825655B2 (en) * 2001-08-31 2004-11-30 Imego Ab Method and arrangement for detecting changes of a magnetic response in magnetic particles

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592043A (en) * 1969-01-27 1971-07-13 Varian Associates Micro-adsorption detector and method of using same
JPS5646450A (en) * 1979-09-21 1981-04-27 Terumo Corp Detector for hematic emulsion in blood specimen
US4690152A (en) * 1985-10-23 1987-09-01 American Mediscan, Inc. Apparatus for epithelial tissue impedance measurements
US5004583A (en) * 1987-01-29 1991-04-02 Medtest Systems, Inc. Universal sensor cartridge for use with a universal analyzer for sensing components in a multicomponent fluid
US5212988A (en) * 1988-02-29 1993-05-25 The Reagents Of The University Of California Plate-mode ultrasonic structure including a gel
US5427663A (en) * 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
DE19520298A1 (de) * 1995-06-02 1996-12-05 Bayer Ag Sortiervorrichtung für biologische Zellen oder Viren
US6818109B2 (en) * 2000-09-29 2004-11-16 Kabushiki Kaisha Toshiba Nucleic acid detections sensor

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3999047A (en) * 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US3941563A (en) * 1974-04-23 1976-03-02 E. I. Du Pont De Nemours & Company Method and apparatus for detecting hexavalent chromium
US5192507A (en) * 1987-06-05 1993-03-09 Arthur D. Little, Inc. Receptor-based biosensors
US5554339A (en) * 1988-11-14 1996-09-10 I-Stat Corporation Process for the manufacture of wholly microfabricated biosensors
US5910286A (en) * 1995-02-21 1999-06-08 Thomson-Csf Highly selective chemical sensor
US6241950B1 (en) * 1998-02-13 2001-06-05 Airxpert Systems, Inc. Fluid sampling system
US6455000B1 (en) * 1999-07-12 2002-09-24 Fantom Technologies Inc. Method and apparatus for measuring the concentration of a gas
US6534012B1 (en) * 2000-08-02 2003-03-18 Sensys Medical, Inc. Apparatus and method for reproducibly modifying localized absorption and scattering coefficients at a tissue measurement site during optical sampling
US6825655B2 (en) * 2001-08-31 2004-11-30 Imego Ab Method and arrangement for detecting changes of a magnetic response in magnetic particles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1623211A4 *

Also Published As

Publication number Publication date
EP1623211A2 (fr) 2006-02-08
EP1623211A4 (fr) 2006-10-25
WO2004097370A2 (fr) 2004-11-11

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