WO2004093734A3 - Premixed self-hardening bone graft pastes - Google Patents

Premixed self-hardening bone graft pastes Download PDF

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Publication number
WO2004093734A3
WO2004093734A3 PCT/US2004/007422 US2004007422W WO2004093734A3 WO 2004093734 A3 WO2004093734 A3 WO 2004093734A3 US 2004007422 W US2004007422 W US 2004007422W WO 2004093734 A3 WO2004093734 A3 WO 2004093734A3
Authority
WO
WIPO (PCT)
Prior art keywords
bone graft
paste
hardening bone
pastes
premixed self
Prior art date
Application number
PCT/US2004/007422
Other languages
French (fr)
Other versions
WO2004093734A2 (en
Inventor
Laurence C Chow
Shozo Takagi
Original Assignee
Ada Foundation
Laurence C Chow
Shozo Takagi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/057,554 external-priority patent/US6793725B2/en
Application filed by Ada Foundation, Laurence C Chow, Shozo Takagi filed Critical Ada Foundation
Priority to CA2521522A priority Critical patent/CA2521522C/en
Priority to JP2006507076A priority patent/JP4668172B2/en
Priority to EP04719777.7A priority patent/EP1622843B1/en
Priority to US10/552,337 priority patent/US7709029B2/en
Publication of WO2004093734A2 publication Critical patent/WO2004093734A2/en
Publication of WO2004093734A3 publication Critical patent/WO2004093734A3/en
Priority to US12/772,843 priority patent/US8282396B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/864—Phosphate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/898—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/02—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
    • C04B28/10—Lime cements or magnesium oxide cements
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/14—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing calcium sulfate cements
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
    • C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ceramic Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)

Abstract

A bone or dental implant material in the form of a paste includes a mixture of calcium phosphate and/or calcium-containing powders, liquid glycerol, organic acid and gelling agent. The paste is stable, resistant to washout and will harden upon exposure to water. Physical characteristics of the paste, including consistency, porosity, and hardening time, are controlled by the choice and ratio of constituents.
PCT/US2004/007422 2001-01-24 2004-03-11 Premixed self-hardening bone graft pastes WO2004093734A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2521522A CA2521522C (en) 2003-04-08 2004-03-11 Premixed self-hardening bone graft pastes
JP2006507076A JP4668172B2 (en) 2003-04-08 2004-03-11 Premixed self-hardening bone graft paste
EP04719777.7A EP1622843B1 (en) 2003-04-08 2004-03-11 Premixed self-hardening bone graft pastes
US10/552,337 US7709029B2 (en) 2001-01-24 2004-03-11 Calcium-containing restoration materials
US12/772,843 US8282396B2 (en) 2001-01-24 2010-05-03 Calcium-containing restoration materials

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/057,554 US6793725B2 (en) 2001-01-24 2002-01-23 Premixed calcium phosphate cement pastes
US46133803P 2003-04-08 2003-04-08
US60/461,338 2003-04-08

Publications (2)

Publication Number Publication Date
WO2004093734A2 WO2004093734A2 (en) 2004-11-04
WO2004093734A3 true WO2004093734A3 (en) 2005-06-30

Family

ID=34713274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/007422 WO2004093734A2 (en) 2001-01-24 2004-03-11 Premixed self-hardening bone graft pastes

Country Status (1)

Country Link
WO (1) WO2004093734A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ550667A (en) * 2004-04-15 2010-10-29 Etex Corp Delayed-setting calcium phosphate pastes for the treatment of orthopedic conditions
KR101410691B1 (en) * 2005-10-21 2014-06-24 에이다 파운데이션 Dual phase cement precursor systems for bone repair
ES2301320B1 (en) * 2005-12-15 2009-05-01 Faleh Tamimi Mariño BRUSHITA CEMENT GRANULATE FRAGUATED WITH GLYCOLIC ACID FOR OSEA REGENERATION.
US8475811B2 (en) 2007-04-20 2013-07-02 Innovative Bioceramix, Inc. Premixed biological hydraulic cement paste composition and using the same
JP2010529091A (en) 2007-06-06 2010-08-26 インノテーレ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Implant materials based on hydraulic cement and their use
WO2010055483A2 (en) 2008-11-12 2010-05-20 Engqvist Haakan Hydraulic cements, methods and products
US8557038B2 (en) 2009-04-22 2013-10-15 American Dental Association Foundation Dual-phase calcium phosphate cement composition
US8795377B2 (en) 2010-03-10 2014-08-05 Ossdsign Ab Implants and methods for correcting tissue defects
US9463046B2 (en) 2011-08-22 2016-10-11 Ossdsign Ab Implants and methods for using such implants to fill holes in bone tissue
GB2513477A (en) * 2011-09-09 2014-10-29 Ossdsign Ab Storage stable premixed hydraulic cement compositions, cements, methods, and articles
US20130066324A1 (en) * 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cements, methods and products
US20130066327A1 (en) 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cement compositions with low ph methods, articles and kits
US8591645B2 (en) * 2011-09-09 2013-11-26 Ossdsign Ab Hydraulic cements with optimized grain size distribution, methods, articles and kits
US8979991B2 (en) 2012-03-21 2015-03-17 Loma Linda University Substances and method for replacing natural tooth material
EP2931325B1 (en) 2012-12-14 2020-02-19 OssDsign AB Cement-forming compositions, monetite cements, implants and methods for correcting bone defects
US10076416B2 (en) 2013-02-12 2018-09-18 Ossdsign Ab Mosaic implants, kits and methods for correcting bone defects
EP3179961B1 (en) 2014-08-14 2020-12-02 OssDsign AB Bone implants for correcting bone defects
US11857558B2 (en) * 2018-09-14 2024-01-02 Angelus Indústria De Produtos Odontológicos S/a Dental and medical compositions having a multiple source of metallic ions
EP4335466A1 (en) 2022-09-08 2024-03-13 Heraeus Medical GmbH Composition for the preparation of a bone substitute material, method for the preparation of a pharmaceutical active substance carrier, pharmaceutical active substance carrier and its use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137812A1 (en) * 2001-01-24 2002-09-26 American Dental Association Health Foundation Premixed calcium phosphate cement pastes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137812A1 (en) * 2001-01-24 2002-09-26 American Dental Association Health Foundation Premixed calcium phosphate cement pastes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9144631B2 (en) 2003-01-27 2015-09-29 Benedicte Asius Ceramic-based injectable implants which are used to fill wrinkles, cutaneous depressions and scars, and preparation method thereof

Also Published As

Publication number Publication date
WO2004093734A2 (en) 2004-11-04

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