WO2004081527A3 - Systems for differential ion mobility analysis - Google Patents

Systems for differential ion mobility analysis Download PDF

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Publication number
WO2004081527A3
WO2004081527A3 PCT/US2004/007213 US2004007213W WO2004081527A3 WO 2004081527 A3 WO2004081527 A3 WO 2004081527A3 US 2004007213 W US2004007213 W US 2004007213W WO 2004081527 A3 WO2004081527 A3 WO 2004081527A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
ion mobility
differential ion
mobility analysis
volatilized
Prior art date
Application number
PCT/US2004/007213
Other languages
French (fr)
Other versions
WO2004081527A2 (en
Inventor
Raanan A Miller
Angela Zapata
Erkinjon G Nazarov
Cristina E Davis
Gary A Eiceman
Anthony B Bashall
Original Assignee
Sionex Corp
Draper Lab Charles S
Raanan A Miller
Angela Zapata
Erkinjon G Nazarov
Cristina E Davis
Gary A Eiceman
Anthony B Bashall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/462,206 external-priority patent/US7005632B2/en
Application filed by Sionex Corp, Draper Lab Charles S, Raanan A Miller, Angela Zapata, Erkinjon G Nazarov, Cristina E Davis, Gary A Eiceman, Anthony B Bashall filed Critical Sionex Corp
Priority to EP04719211A priority Critical patent/EP1601948A2/en
Priority to CA002518703A priority patent/CA2518703A1/en
Publication of WO2004081527A2 publication Critical patent/WO2004081527A2/en
Publication of WO2004081527A3 publication Critical patent/WO2004081527A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath

Abstract

NEW ABSTRACT Disclosed herein are systems, methods and apparatus ( 10), for detection and identification of analytes in a volatilized or volatilizable sample (A), using the mobility-based signature that is produced when the volatilized sample is passed through a differential ion mobility spectrometry (DMS) device (C).
PCT/US2004/007213 2003-03-10 2004-03-10 Systems for differential ion mobility analysis WO2004081527A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04719211A EP1601948A2 (en) 2003-03-10 2004-03-10 Systems for differential ion mobility analysis
CA002518703A CA2518703A1 (en) 2003-03-10 2004-03-10 Systems for differential ion mobility analysis

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US45345103P 2003-03-10 2003-03-10
US45328703P 2003-03-10 2003-03-10
US45344803P 2003-03-10 2003-03-10
US60/453,448 2003-03-10
US60/453,287 2003-03-10
US60/453,451 2003-03-10
US46830603P 2003-05-06 2003-05-06
US60/468,306 2003-05-06
US10/462,206 US7005632B2 (en) 2002-04-12 2003-06-13 Method and apparatus for control of mobility-based ion species identification
US10/462,206 2003-06-13
US69770803A 2003-10-30 2003-10-30
US10/697,708 2003-10-30
US53081503P 2003-12-18 2003-12-18
US60/530,815 2003-12-18
US54900404P 2004-03-01 2004-03-01
US60/549,004 2004-03-01
US79477604A 2004-03-05 2004-03-05
US10/794,776 2004-03-05

Publications (2)

Publication Number Publication Date
WO2004081527A2 WO2004081527A2 (en) 2004-09-23
WO2004081527A3 true WO2004081527A3 (en) 2007-04-19

Family

ID=35261943

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/007213 WO2004081527A2 (en) 2003-03-10 2004-03-10 Systems for differential ion mobility analysis

Country Status (3)

Country Link
EP (1) EP1601948A2 (en)
CA (1) CA2518703A1 (en)
WO (1) WO2004081527A2 (en)

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CN105122058A (en) * 2013-02-20 2015-12-02 亚历法克斯控股有限公司 Method to identify bacterial species by means of gas chromatography/mass spectrometry in biological samples
CN109738569A (en) * 2019-02-28 2019-05-10 云南中烟工业有限责任公司 A kind of imitative identification of cigarettes method of the height based on SPME-GC-MS

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DE102007033906A1 (en) * 2007-07-20 2009-01-29 Gesellschaft zur Förderung der Analytischen Wissenschaften e.V. Gas i.e. human exhaled air, analyzing method, involves guiding gas sample that is isothermally conducted from gas sample accommodation into ion mobility spectrometer and is continuously warmed up at retention time
US20090111189A1 (en) * 2007-10-26 2009-04-30 Alberta Research Council Inc. Organic and inorganic mercury detection
CN102313775B (en) * 2010-07-06 2013-05-29 同方威视技术股份有限公司 Ionic migration spectrometer and detection method thereof
DE102010045491B4 (en) * 2010-09-16 2012-10-11 Continental Automotive Gmbh Method for detecting macromolecular organic silicon compounds and device therefor
US9173389B2 (en) * 2010-11-18 2015-11-03 Auburn University Systems and methods to deliver and maintain volatile compounds
DE102011017280A1 (en) * 2011-04-15 2012-10-18 Fagus-Grecon Greten Gmbh & Co Kg Method of measuring wood material emitting volatiles and apparatus for measuring the emission of volatile materials from wood-based materials
IN2014MN02060A (en) * 2012-03-18 2015-08-21 Univ Kyushu Nat Univ Corp
WO2015009613A2 (en) * 2013-07-16 2015-01-22 Cdx, Inc. Apparatus for detection and delivery of volatilized compounds and related methods
GB201314252D0 (en) 2013-08-08 2013-09-25 Smiths Detection Watford Ltd Apparatus and method
US9057699B2 (en) 2013-11-21 2015-06-16 Hamilton Sundstrand Corporation High temperature differential ion mobility spectroscopy
GB2521753B (en) * 2013-11-21 2020-12-30 Hamilton Sundstrand Corp High temperature differential ion mobility spectroscopy
WO2015087985A1 (en) 2013-12-11 2015-06-18 株式会社資生堂 Marker for early diagnosis of kidney failure
EP2887065A1 (en) 2013-12-17 2015-06-24 Forest Laboratories Deutschland GmbH Method for breath gas analysis for infectious diseases
CN104007214B (en) * 2014-02-14 2015-12-02 西安科技大学 A kind of method detecting volatile ingredient in fragrant product based on PY-GC-MS
US20210282678A1 (en) * 2017-03-23 2021-09-16 Technion Research & Development Foundation Limited Device and methods for detection and monitoring of tuberculosis
DE102017220514A1 (en) * 2017-11-16 2019-05-16 Unisensor Sensorsysteme Gmbh Method and device for detecting foreign substances in a liquid medium
GB2568876A (en) * 2017-11-27 2019-06-05 Imperial Innovations Ltd Detection of biomarkers
CN110057757B (en) * 2018-01-18 2022-04-26 深圳市理邦精密仪器股份有限公司 Hemoglobin and hemoglobin derivative identification and identification network construction method and device
CN110879265B (en) * 2019-11-07 2023-03-31 云南中烟工业有限责任公司 Method for simulating and measuring heat migration quantity of formaldehyde and acetaldehyde to smoke in cigarette blasting beads
CN110907556A (en) * 2019-12-10 2020-03-24 湖北中烟工业有限责任公司 GC-IMS-based evaluation method for tobacco aroma of different producing areas
JP7276751B2 (en) * 2020-03-05 2023-05-18 新東工業株式会社 Gas measuring instrument and gas measuring method
IL296078A (en) * 2020-03-19 2022-11-01 Respiration Scan Ltd Identification of viruses by analysis of volatile organic compounds related to viral replication
CN111551644A (en) * 2020-04-03 2020-08-18 黄埔海关技术中心 Method for tracing origin of imported fragrant rice based on ion mobility spectrometry technology
AU2021370895A1 (en) 2020-10-29 2023-06-08 Industrial Polymers and Chemicals, Inc. Air filter with pathogen monitoring and inactivation
RU2759151C1 (en) * 2020-11-18 2021-11-09 Федеральное государственное казенное военное образовательное учреждение высшего образования "Военный учебно-научный центр Военно-воздушных сил "Военно-воздушная академия имени профессора Н.Е. Жуковского и Ю.А. Гагарина" (г. Воронеж) Министерства обороны Российской Федерации Ultrahigh frequency device for determining electrophysical parameters for evaluating defects in multilayer dielectric and magnetodielectric coatings
CN112684061A (en) * 2021-01-19 2021-04-20 泸州品创科技有限公司 Quality control method and system for tea aroma extraction process
DE102021117816A1 (en) 2021-07-09 2023-01-12 B. Braun Melsungen Aktiengesellschaft Measuring device with two consecutive measurements

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US5508204A (en) * 1995-01-12 1996-04-16 Norman Clinical Laboratories, Inc. Multiple sample sequential chemical analysis
US20010030285A1 (en) * 1999-07-21 2001-10-18 Miller Raanan A. Method and apparatus for chromatography-high field asymmetric waveform Ion mobility spectrometry
US6495823B1 (en) * 1999-07-21 2002-12-17 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US6512224B1 (en) * 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US20030052263A1 (en) * 2001-06-30 2003-03-20 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
US6540691B1 (en) * 1999-01-12 2003-04-01 Michael Phillips Breath test for the detection of various diseases
US20030132380A1 (en) * 1999-07-21 2003-07-17 Sionex Corporation Micromachined field asymmetric ion mobility filter and detection system
US6680203B2 (en) * 2000-07-10 2004-01-20 Esperion Therapeutics, Inc. Fourier transform mass spectrometry of complex biological samples
US6690004B2 (en) * 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US20040094704A1 (en) * 2002-04-12 2004-05-20 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
US20050051719A1 (en) * 1999-07-21 2005-03-10 Sionex Corporation Systems for differential ion mobility analysis

Patent Citations (13)

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US5508204A (en) * 1995-01-12 1996-04-16 Norman Clinical Laboratories, Inc. Multiple sample sequential chemical analysis
US6540691B1 (en) * 1999-01-12 2003-04-01 Michael Phillips Breath test for the detection of various diseases
US20030132380A1 (en) * 1999-07-21 2003-07-17 Sionex Corporation Micromachined field asymmetric ion mobility filter and detection system
US6512224B1 (en) * 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US6495823B1 (en) * 1999-07-21 2002-12-17 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US20010030285A1 (en) * 1999-07-21 2001-10-18 Miller Raanan A. Method and apparatus for chromatography-high field asymmetric waveform Ion mobility spectrometry
US6690004B2 (en) * 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US20050051719A1 (en) * 1999-07-21 2005-03-10 Sionex Corporation Systems for differential ion mobility analysis
US7057168B2 (en) * 1999-07-21 2006-06-06 Sionex Corporation Systems for differential ion mobility analysis
US20060151687A1 (en) * 1999-07-21 2006-07-13 Sionex Corporation Systems for differential ion mobility analysis
US6680203B2 (en) * 2000-07-10 2004-01-20 Esperion Therapeutics, Inc. Fourier transform mass spectrometry of complex biological samples
US20030052263A1 (en) * 2001-06-30 2003-03-20 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
US20040094704A1 (en) * 2002-04-12 2004-05-20 Sionex Corporation Method and apparatus for control of mobility-based ion species identification

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105122058A (en) * 2013-02-20 2015-12-02 亚历法克斯控股有限公司 Method to identify bacterial species by means of gas chromatography/mass spectrometry in biological samples
CN109738569A (en) * 2019-02-28 2019-05-10 云南中烟工业有限责任公司 A kind of imitative identification of cigarettes method of the height based on SPME-GC-MS
CN109738569B (en) * 2019-02-28 2022-02-01 云南中烟工业有限责任公司 High-imitation cigarette identification method based on SPME-GC-MS

Also Published As

Publication number Publication date
CA2518703A1 (en) 2004-09-23
WO2004081527A2 (en) 2004-09-23
EP1601948A2 (en) 2005-12-07

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