WO2004080424A3 - Methods and compositions for neurite outgrowth detection - Google Patents

Methods and compositions for neurite outgrowth detection Download PDF

Info

Publication number
WO2004080424A3
WO2004080424A3 PCT/US2004/007749 US2004007749W WO2004080424A3 WO 2004080424 A3 WO2004080424 A3 WO 2004080424A3 US 2004007749 W US2004007749 W US 2004007749W WO 2004080424 A3 WO2004080424 A3 WO 2004080424A3
Authority
WO
WIPO (PCT)
Prior art keywords
neurite outgrowth
methods
compositions
present
detection
Prior art date
Application number
PCT/US2004/007749
Other languages
French (fr)
Other versions
WO2004080424A2 (en
Inventor
Li-An Yeh
Gregory D Cuny
Deepa Padmanaban
Kai Ding
Original Assignee
Brigham & Womens Hospital
Li-An Yeh
Gregory D Cuny
Deepa Padmanaban
Kai Ding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital, Li-An Yeh, Gregory D Cuny, Deepa Padmanaban, Kai Ding filed Critical Brigham & Womens Hospital
Publication of WO2004080424A2 publication Critical patent/WO2004080424A2/en
Publication of WO2004080424A3 publication Critical patent/WO2004080424A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4718—Lipocortins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates generally to methods for detecting neurite outgrowth. The methods of the present invention are particularly useful in developing high-throughput assays to measure neurite outgrowth. The present invention further relates to high-throughput assays for screening compounds that modulate neurite outgrowth; such compounds can be used to prevent and treat diseases and conditions relating to neurodegeneration.
PCT/US2004/007749 2003-03-13 2004-03-13 Methods and compositions for neurite outgrowth detection WO2004080424A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45425403P 2003-03-13 2003-03-13
US60/454,254 2003-03-13

Publications (2)

Publication Number Publication Date
WO2004080424A2 WO2004080424A2 (en) 2004-09-23
WO2004080424A3 true WO2004080424A3 (en) 2005-01-27

Family

ID=32990889

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/007749 WO2004080424A2 (en) 2003-03-13 2004-03-13 Methods and compositions for neurite outgrowth detection

Country Status (1)

Country Link
WO (1) WO2004080424A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2929518B1 (en) * 2008-04-04 2013-06-28 Oreal COSMETIC USE OF APPENDIX II PROTEINS FOR THE TREATMENT OF SKIN AGING

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FOX M T ET AL: "INCREASES IN P11 AND ANNEXIN II PROTEINS CORRELATE WITH DIFFERENTIATION IN THE PC12 PHEOCHROMOCYTOMA", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 177, no. 3, 1991, pages 1188 - 1193, XP001180583, ISSN: 0006-291X *
JACOVINA ANDREW T ET AL: "Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 52, 28 December 2001 (2001-12-28), pages 49350 - 49358, XP001180582, ISSN: 0021-9258 *
XING X ET AL: "Utilization of a copper-catalyzed diaryl ether synthesis for the preparation of verbenachalcone", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 58, no. 39, 23 September 2002 (2002-09-23), pages 7903 - 7910, XP004381445, ISSN: 0040-4020 *

Also Published As

Publication number Publication date
WO2004080424A2 (en) 2004-09-23

Similar Documents

Publication Publication Date Title
WO2007062090A8 (en) Methods and compositions related to b cell assays
WO2006057918A3 (en) Detection of nucleic acid variation by cleavage-amplification method
WO2006031644A3 (en) Immobilized probes and methods of detecting conformationally altered prion proteins
WO2006110762A3 (en) Pharmaceutical compositions for and methods of inhibiting hcv replication
WO2004055519A3 (en) Specific markers for pancreatic cancer
WO2007070359A3 (en) Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof
EP1546118A4 (en) Compositions and methods for detection and isolation of phosphorylated molecules
WO2003045310A8 (en) Digital assay
CA2697508A1 (en) Method for detecting gynecologic cancer
AU2003293704A8 (en) Methods and kits for assays of rapid screening of diabetes
WO2004070351A3 (en) Protein fragment complementation assays for high-throughput and high-content screening
WO2006130551A3 (en) Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
WO2007131191A3 (en) Mass spectrometry methods for multiplexed quantification of protein kinases and phosphatases
EP2100899A3 (en) Compounds for proteasome enzyme inhibition
WO2007120638A3 (en) Methods and compositions for modulating glycosylation
WO2005003394A3 (en) Bio-barcode based detection of target analytes
WO2005012329A3 (en) Kinase and phosphatase assays
WO2005042771A3 (en) Colorimetric substrates, colorimetric sensors, and methods of use
ATE221657T1 (en) DISTURBANCE BY RHEUMA FACTORS
WO2001040504A3 (en) Methods and compositions for detecting nitroaromatic compounds
WO2004080424A3 (en) Methods and compositions for neurite outgrowth detection
WO2007038331A8 (en) Novel chemical compounds
WO2006028565A3 (en) Novel methods for high-throughput genome-wide location analysis
WO2003053855A3 (en) Rapid high-throughput screen for detecting biological species in ballast water
WO2007066129A3 (en) A method of detecting skeletal muscle damage

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase