WO2004078141A3 - Hemipteran membrane-bound matrix metalloproteinase - Google Patents

Hemipteran membrane-bound matrix metalloproteinase Download PDF

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Publication number
WO2004078141A3
WO2004078141A3 PCT/US2004/006667 US2004006667W WO2004078141A3 WO 2004078141 A3 WO2004078141 A3 WO 2004078141A3 US 2004006667 W US2004006667 W US 2004006667W WO 2004078141 A3 WO2004078141 A3 WO 2004078141A3
Authority
WO
WIPO (PCT)
Prior art keywords
hemipteran
membrane
bound matrix
matrix metalloproteinases
matrix metalloproteinase
Prior art date
Application number
PCT/US2004/006667
Other languages
French (fr)
Other versions
WO2004078141A2 (en
Inventor
Cancan Huang
Blake Halling
James Russell Eldridge
Paul Allenza
Original Assignee
Fmc Corp
Cancan Huang
Blake Halling
James Russell Eldridge
Paul Allenza
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp, Cancan Huang, Blake Halling, James Russell Eldridge, Paul Allenza filed Critical Fmc Corp
Publication of WO2004078141A2 publication Critical patent/WO2004078141A2/en
Publication of WO2004078141A3 publication Critical patent/WO2004078141A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43552—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from insects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Abstract

Novel nucleic acid sequences encoding Hemipteran membrane-bound matrix metalloproteinases, and recombinant expressions and host cells comprising the same are disclosed. Host cells expressing Hemipteran membrane-bound matrix metalloproteinases and methods of producing the Hemipteran membrane-bound matrix metalloproteinases are also disclosed. Methods of identifying modulators and/or inhibitors of Hemipteran membrane-bound matrix metalloproteinases are disclosed.
PCT/US2004/006667 2003-03-05 2004-03-04 Hemipteran membrane-bound matrix metalloproteinase WO2004078141A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45231603P 2003-03-05 2003-03-05
US60/452,316 2003-03-05

Publications (2)

Publication Number Publication Date
WO2004078141A2 WO2004078141A2 (en) 2004-09-16
WO2004078141A3 true WO2004078141A3 (en) 2007-12-06

Family

ID=32962711

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/006667 WO2004078141A2 (en) 2003-03-05 2004-03-04 Hemipteran membrane-bound matrix metalloproteinase

Country Status (1)

Country Link
WO (1) WO2004078141A2 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No relevant documents disclosed. *

Also Published As

Publication number Publication date
WO2004078141A2 (en) 2004-09-16

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