WO2004075922A3 - Composes comprenant au moins une substance active et au moins un vecteur relies par un agent de liaison, leurs utilisation et lesdits agents de liaison - Google Patents
Composes comprenant au moins une substance active et au moins un vecteur relies par un agent de liaison, leurs utilisation et lesdits agents de liaison Download PDFInfo
- Publication number
- WO2004075922A3 WO2004075922A3 PCT/FR2004/000413 FR2004000413W WO2004075922A3 WO 2004075922 A3 WO2004075922 A3 WO 2004075922A3 FR 2004000413 W FR2004000413 W FR 2004000413W WO 2004075922 A3 WO2004075922 A3 WO 2004075922A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- carrier
- active substance
- compounds
- binding
- binding agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention concerne un composé comprenant au moins une substance active et au moins un vecteur, lesdits substance active et vecteur étant reliés par un agent de liaison, l'utilisation dudit composé pour la préparation d'une composition pharmaceutique, ladite composition pharmaceutique. La présente invention concerne également lesdits agents de liaison.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0302242A FR2851471B1 (fr) | 2003-02-24 | 2003-02-24 | Composes comprenant au moins une substance active et au moins un vecteur relies par un agent de liaison, leurs utilisations et lesdits agents de liaison |
FR03/02242 | 2003-02-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004075922A2 WO2004075922A2 (fr) | 2004-09-10 |
WO2004075922A3 true WO2004075922A3 (fr) | 2005-01-20 |
Family
ID=32799540
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2004/000413 WO2004075922A2 (fr) | 2003-02-24 | 2004-02-24 | Composes comprenant au moins une substance active et au moins un vecteur relies par un agent de liaison, leurs utilisation et lesdits agents de liaison |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2851471B1 (fr) |
WO (1) | WO2004075922A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0037388A2 (fr) * | 1980-03-31 | 1981-10-07 | Institut International De Pathologie Cellulaire Et Moleculaire | Formes pharmaceutiques, leur préparation et les compositions qui les contiennent |
EP0394989A2 (fr) * | 1989-04-28 | 1990-10-31 | Fujisawa Pharmaceutical Co., Ltd. | Composés peptidiques, leur préparation et médicaments les renfermant |
JP2001206897A (ja) * | 2000-01-26 | 2001-07-31 | Nippon Seibutsu Seizai:Kk | ハイドロキシプロリン誘導体 |
FR2836474A1 (fr) * | 2002-02-22 | 2003-08-29 | Synt Em | Composes, compositions et methode pour le transport des molecules de cyclosporine a travers la barriere hemato-encephalique |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63502716A (ja) * | 1986-03-07 | 1988-10-13 | マサチューセッツ・インステチュート・オブ・テクノロジー | 糖タンパク安定性の強化方法 |
HUP0300590A2 (hu) * | 2000-03-15 | 2003-07-28 | Bristol-Myers Squibb Pharma Company | Peptidázzal hasítható, célzott antineoplasztikus szerek és terápiás alkalmazásuk |
WO2002036628A2 (fr) * | 2000-11-02 | 2002-05-10 | Maxygen Aps | Nouveaux polypeptides $g(b) interferon multimeres |
-
2003
- 2003-02-24 FR FR0302242A patent/FR2851471B1/fr not_active Expired - Fee Related
-
2004
- 2004-02-24 WO PCT/FR2004/000413 patent/WO2004075922A2/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0037388A2 (fr) * | 1980-03-31 | 1981-10-07 | Institut International De Pathologie Cellulaire Et Moleculaire | Formes pharmaceutiques, leur préparation et les compositions qui les contiennent |
EP0394989A2 (fr) * | 1989-04-28 | 1990-10-31 | Fujisawa Pharmaceutical Co., Ltd. | Composés peptidiques, leur préparation et médicaments les renfermant |
JP2001206897A (ja) * | 2000-01-26 | 2001-07-31 | Nippon Seibutsu Seizai:Kk | ハイドロキシプロリン誘導体 |
FR2836474A1 (fr) * | 2002-02-22 | 2003-08-29 | Synt Em | Composes, compositions et methode pour le transport des molecules de cyclosporine a travers la barriere hemato-encephalique |
Non-Patent Citations (4)
Title |
---|
GREENWELL DAVID R ET AL: "Peptide-templated saccharide synthesis on a solid support.", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH), vol. 41, no. 7, 2 April 2002 (2002-04-02), pages 1215 - 1218, XP002291876, ISSN: 0570-0833 * |
LIFFERTH, AXEL ET AL: "Synthesis and structure of proline-ring-modified actinomycins of the X-type", ZEITSCHRIFT FUER NATURFORSCHUNG, B: CHEMICAL SCIENCES, CODEN: ZNBSEN; ISSN: 0932-0776, vol. 54, no. 5, 1999, pages 681 - 691, XP001194726 * |
POIANI G J ET AL: "CONJUGATES OF CIS-4-HYDROXY-L-PROLINE AND POLY(PEG-LYS), A WATER SOLUBLE POLY(ETHER URETHANE): SYNTHESIS AND EVALUATION OF ANTIFIBROTIC EFFECTS IN VITRO AND IN VIVO", BIOCONJUGATE CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 5, no. 6, 1 November 1994 (1994-11-01), WASHINGTON, US, pages 621 - 630, XP000484177, ISSN: 1043-1802 * |
ROTHBARD J B ET AL: "Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation", NATURE MEDICINE, vol. 6, no. 11, November 2000 (2000-11-01), UNITED STATES, pages 1253 - 1257, XP002291867, ISSN: 1078-8956 * |
Also Published As
Publication number | Publication date |
---|---|
WO2004075922A2 (fr) | 2004-09-10 |
FR2851471B1 (fr) | 2006-07-28 |
FR2851471A1 (fr) | 2004-08-27 |
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