WO2004075740A1

WO2004075740A1 - Cut tissue piece recovery device

Info

Publication number: WO2004075740A1
Application number: PCT/JP2004/000940
Authority: WO
Inventors: Ken Nishikawa; Yasushi Sano
Original assignee: Zeon Corporation
Priority date: 2003-02-25
Filing date: 2004-01-30
Publication date: 2004-09-10
Also published as: JPWO2004075740A1

Abstract

A cut tissue piece recovery device (50), comprising a tubular body member (51) and a trap member (60) mounted in the body member, wherein a circulating passage (55) and a trap member mounting port (57) are formed in the body member, a filter part (63) and a head part (65) are formed on the trap member, and the trap part is disposed so that the filter part crosses the circulating passage and the trap member mounting port is closed by the head part when the trap part is mounted in the body member. Also, the mounting of the trap member in the body member and the removal of the trap member from the body member are freely performed. Thus, the cut tissue piece recovery device capable of being easily downsized and operated only by one hand and capable of easily fixing a recovered cut tissue piece can be provided. In addition, a tissue fixing container capable of easily fixing the cut tissue piece recovered by the cut tissue piece recovery device can be provided.

Description

Description Tissue resection collection tool Technical field

The present invention relates to a device (hereinafter referred to as a “tissue resection-recovery device”) for recovering a tissue piece that has been resected through an endoscope and aspirated outside the body, a component thereof, and a tissue fixation And a tissue fixing device. Background art

In recent years, the scope of diagnosis and surgery that can be performed using an endoscope is expanding. For example, when endoscopic examination finds diseased tissue, such as polyp II superficial cancer, in the body cavity, the removal of the diseased tissue and collection of tissue fragments for pathological tissue diagnosis are also performed through the endoscope. It is being done.

In many endoscopes capable of removing or collecting tissue, a treatment instrument channel for introducing a treatment instrument such as a forceps and a snare and an air supply channel are formed inside. The channel is open at the end of the endoscope. The treatment instrument channel is also used as a discharge channel (aspiration channel) for discharging the contents of the body cavity and the like out of the body.

If the size of the tissue piece cut with the above-mentioned treatment tool (hereinafter referred to as “tissue resection piece”) is large enough to pass through the drainage channel, the tissue resection piece can be removed from the body via the drainage channel. Excreted (aspirated), and usually collected for histopathological diagnosis. In this recovery, a trap is often provided in a flow path (pipe) between the negative pressure generator for generating a negative pressure in the discharge channel and the discharge channel, and the tissue resection is captured by the trap. This is done by: In recent years, miniaturization of imaging devices and the like used in endoscopes has been progressing, and the discharge channels have been increased in diameter with the miniaturization of the imaging devices.

For example, U.S. Pat. No. 4,643,197 has a container portion and a lid attached to the open end of the container portion, and one or more filters are provided at the open end of the container portion. Department is located A tissue resection tool is described. In this tissue excision piece collection tool, the tissue excision piece and the body fluid are supplied from one tube connected to the lid, and the tissue excision piece is captured by the filter unit. After flowing into the container, the bodily fluid is sucked out through another tube inserted into the container through the lid.

In the case where a plurality of filter sections are arranged at the opening end of the container section, a plurality of openings are arranged together with these filter sections. When the tissue excision is to be captured, the lid and the container are relatively rotated so that the tissue excision and the body fluid are supplied to a desired filter. When it is not necessary to capture the body fluid, the lid and the container are relatively rotated so that the body fluid is supplied to a desired opening. In any case, the relative rotation between the lid and the container is performed manually.

The tissue excision piece retrieval device described in U.S. Pat.No. 4,643,197 is relatively large and may obstruct operation of an endoscope-related device such as a light source device. . In addition, when a plurality of filter portions are formed on the lid portion, in order to cause the desired filter portion to capture the tissue excision pieces, the lid portion is gripped by one hand and the container portion is gripped by the other hand. In addition, the lid and the container must be relatively rotated by a desired amount, and the operation is complicated.

Further, it is desired that the captured and collected tissue excision be fixed by immersing it in a fibrous tissue fixing agent so that it does not deteriorate until a histopathological diagnosis is performed. In the tissue excision piece collection tool described in No. 197, after removing the container from the lid, the tissue excision trapped in the filter part is taken out with a suitable instrument and placed in a tissue fixing container. The transfer force or, if there is only one filter section, the entire filter section must be transferred to a container for tissue fixation, which is complicated.

Accordingly, a first object of the present invention is to provide a tissue excision piece collection tool which can be easily miniaturized, can be operated with one hand, and can easily fix the collected tissue excision piece, and a component thereof. Make it an issue.

A second object of the present invention is to provide a tissue fixing container and a tissue fixing device that can easily fix a tissue excision piece collected by the tissue excision piece collecting tool. Disclosure of the invention

The present inventors have conducted intensive studies on the structure of the tissue resection retrieving tool and found that By combining the member with a trap member that can be freely attached to and detached from the main body member, the first problem can be solved, and the second problem can also be solved. It was completed.

Thus, according to the first aspect of the present invention, the discharge channel of the endoscope and the negative pressure generating device for generating a negative pressure in the discharge channel are arranged in a pipe, and the discharge channel is provided from the discharge channel. A collecting tool for collecting a cut piece of thread and tissue transferred into the conduit, comprising: a tubular main body member; and a trap member loaded in the main body member. A flow path serving as a section of the tract, and a trap member loading port for loading the trap member, wherein the trap member has a filter section in which a filter medium for capturing the tissue excision piece is disposed; A head portion connected to the filter portion, wherein when the trap member is loaded into the main body member, the filter portion is disposed so as to cross the flow passage. The trap member loading port is Is closed, the loading of the trap member to the body member, and the tissue ablation piece collection device removal is freely of the trap member from the body member.

The above-mentioned pipeline is divided into a first pipeline on the discharge channel side and a second pipeline on the negative pressure generator side with the location of the main body member as a boundary, and the main body member is connected to the first pipeline. And a second connector connected to the second conduit, and the inside of each of the first connector and the second connector forms a part of the flow passage. Is preferred.

Further, it is preferable that the main body member has a guide groove for guiding the filter portion to a predetermined position when the trap member is loaded.

The filter section has a first holding section having an opening at the center, and a second holding section having an opening at the center corresponding to the opening, and the filter medium is sandwiched between the first holding section and the second holding section. Those that can do so are preferred.

It is preferable that the filter medium is arranged in a relaxed state on the filter unit.

Further, it is preferable that the filter medium can be visually recognized when the trap member in which the filter medium is disposed in the filter portion is loaded into the main body member.

It is preferable that the apparatus further includes a cap member that is mounted on the trap member loading port when the trap member is not loaded on the main body member and that can seal the trap member loading port. According to a second aspect of the present invention, there is provided the above-mentioned main body member as a component of the tissue excision piece collecting device. According to a third aspect of the present invention, the main body member is provided as a component of the tissue excision piece collecting tool. A trap member is provided.

According to a fourth aspect of the present invention, there is provided a tissue fixing container which can be used for fixing a tissue excision piece collected by the above-described tissue excision piece collection tool of the present invention. Therefore, the tissue fixing container has a content capable of accommodating the tissue excision pieces captured by the filter section together with the filter section, and can be sealed by the head section when the tissue excision pieces are accommodated together with the filter section. Is provided.

According to a fifth aspect of the present invention, there is provided a tissue fixing device including the above-described trap member and a tissue fixing container.

According to a sixth aspect of the present invention, there is provided a method for collecting a tissue section using the above-described tissue resection section recovery tool of the present invention.

According to a seventh aspect of the present invention, there is provided a method for fixing a tissue excision piece using the above-described tissue fixing device of the present invention. BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 is a schematic diagram showing a tissue excision piece collection tool according to an embodiment of the present invention and an example of an endoscope system provided with the tissue excision piece collection tool.

FIGS. 2 (A) and 2 (B) are exploded perspective views schematically showing the tissue excision piece collecting tool shown in FIG.

FIG. 3 is a schematic diagram showing a cross-sectional structure of the tissue excision piece collection tool shown in FIGS. 2 (A) and 2 (B).

FIG. 4 is a cross-sectional view schematically showing a state when the tissue excision piece collecting tool shown in FIGS. 2 (A) and 2 (B) is used.

FIG. 5 schematically shows a cap member, which is attached to the main body member constituting the tissue excision piece collecting tool shown in FIGS. 2A and 2B as necessary, together with the main body member. 3 is an exploded perspective view shown in FIG.

FIG. 6 is an exploded perspective view schematically showing a state in which a trap member after capturing a tissue excision is accommodated in a tissue fixing container according to an embodiment of the present invention. FIG. 7 is a perspective view schematically showing a state in which the tissue excision pieces shown in FIG. 6 are accommodated together with the trap members in the tissue fixing container shown in FIG. BEST MODE FOR CARRYING OUT THE INVENTION

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.

Embodiment relating to tissue excision piece collection tool and its constituent members>

FIG. 1 schematically shows an example of an endoscope system provided with a tissue excision piece collecting tool according to the present invention. The endoscope system 80 shown in the figure includes an endoscope 10, a main body device 20, a negative pressure generator 40, and a tissue excision piece collecting tool 50.

The endoscope 10 is connected to, for example, a first cord section 12 in which various channels such as a treatment instrument channel, an image pickup device, a light guide, and the like are incorporated, and is connected to the first cord section 12. the tip operation and the first code part 1 _2, the operation unit for controlling the on-off of the water or air into a body cavity or the like (not shown.), Universal co over to connect the operation portion main unit 2 0 15

The main unit 20 has a light source device (not shown), a data processing unit 22, and a monitor unit 25.

When examining a desired part of the body with the endoscope system 80, the light emitted from the light source device is guided to the tip of the endoscope 10 by a light guide and used as illumination light, while imaging by an image sensor is performed. Done. The video signal from the image sensor is sent to the data processing unit 22 via the first code unit 12, the operation unit, and the universal code 15, where it is subjected to predetermined processing and then to the monitor unit 25. It is sent and becomes a predetermined playback video. Endoscopic system 80 removes diseased tissue and collects tissue fragments for histopathological diagnosis, while observing the image displayed on the monitor section 25 while viewing treatment tools such as forceps and a snare inserted into the treatment tool channel. This is performed using At this time, if blood or bodily fluid adheres or exudes to the surface of the body tissue, accurate diagnosis and operation become difficult. Similarly, even if blood, body fluid, or the like adheres to the lens surface of the image sensor, accurate diagnosis and operation become difficult.

Therefore, in order to remove the above-mentioned blood, body fluid, and the like, the inside of each of the universal cord 15 and the first cord section 12 is provided with a first cord section 1 from the base of the main unit 20 in the universal cord 15. At the tip of 2, air supply channel, water supply channel, And discharge (suction) channels are formed. One end of each of these channels is open at the tip of the first cord portion 12. It should be noted that the water supply channel and the discharge channel may not be separate channels from the treatment instrument channel, and the treatment instrument channel may also serve as the water supply channel and the discharge channel.

The other end of each of the air supply channel and the water supply channel is connected to the cord 19 at the main unit side connector 17 of the universal cord 15. The code 19 has a channel connected to the air supply channel and a channel connected to the water supply channel, and one end of each channel in the code 19 is connected to an air supply device or an air supply device (not shown). Is connected to the water supply device. As described above, the treatment instrument channel can be used as a water supply channel.

The gas or liquid sent from the air supply device or the water supply device is supplied to the air supply channel or the water supply channel in the endoscope 10 via the code 19. These gases and liquids are used to remove blood, body fluid, etc. attached to or exuding from the surface of body tissue, or to remove blood, body fluid, etc., attached to the lens surface of the image sensor. Inject from the tip of the first code section 12 in accordance with the operation of the operation section 10.

The other end of the discharge channel communicates with the conduit 30 at the main unit-side connector 17 of the universal cord 15, and one end of the conduit 30 is connected to the negative pressure generator 40. Have been. When a negative pressure is generated by the negative pressure generator 40, a negative pressure is generated in the pipe 30 and the discharge channel, and a suction force is generated. By operating the negative pressure generator 40 at a desired time to make the discharge channel in the first cord section 12 a negative pressure, blood or body fluid attached to or exuding from the body tissue surface, or from the water supply channel. The injected liquid can be sucked and removed. Similarly, a tissue excision cut with the above-mentioned treatment tool can be sucked.

The pipe 30 can be divided into a first pipe 32 on the connector section 17 side (discharge channel side) and a second pipe 34 on the negative pressure generator 40 side. When the tissue excision piece is sucked by the discharge channel, the tissue excision piece is transferred from the discharge channel to the pipe 30. Between the two pipes 34, the thread and tissue cutting piece collecting tool 50 of the present embodiment is arranged. The blood, body fluid, etc. transferred from the discharge channel to the conduit 30 are collected by the tissue excision piece collection tool 50 and the negative pressure generator 40. Is collected in a container (not shown) arranged between them.

Hereinafter, the appearance of the tissue excision piece collection tool 50 will be described in detail with reference to FIGS. 2 (A) and 2 (B). It will be described in detail with reference.

2 (A) and 2 (B) are exploded perspective views schematically showing the tissue excision piece collecting tool 50, respectively. As shown in these figures, the tissue excision piece collecting tool 50 includes a tubular main body member 51 and a trap member 60 loaded into the main body member 51.

The main body member 51 includes a hollow tubular portion 52, a first connector portion 53 attached to one longitudinal end of the tubular portion 52, and a second longitudinal end of the tubular portion 52. A second connector portion 54 attached thereto, a trap member loading port 57 formed on the outer peripheral surface of the tubular portion 52 and communicating with the internal space 52 a of the tubular portion 52, and a trap member loading And a collar 59 formed around the mouth 57.

Each of the first connector portion 53 and the second connector portion 54 has through holes 53a, 54a communicating with the internal space 52a, and the trap member 60 is connected to the main body member 51. When it is loaded into the pipe, the inner space 52a, the through holes 53a and 54a, and the lower surface of the head 65 described later form a section of the conduit 30 (see FIG. 1). Flow passage that can be

5 5 is formed.

The outline of the outer opening end of the trap member loading port 57 has a shape (for example, a circle) and a size that can be sealed by the trap member 60 described below.

The trap member 60 has a filter section 63 in which a filter medium 61 for capturing a tissue excision piece is disposed. The filter portion 63 includes a first holding portion 63 a having an opening at the center (see FIG. 2B) and a second holding portion having a center opening corresponding to the opening at the first holding portion 63 a. The filter medium 61 can be sandwiched between the holding portion 63b (see FIG. 2B). A head portion 65 is formed so as to be continuous with the filter portion 63.

The head portion 65 has a shape (for example, a circle) and a size corresponding to the contour shape of the trap member loading port 57 in plan view, and protrudes outside the filter portion 63. Head part

An air-tight material 65 a such as an O-ring is attached to the center of the thickness 65 in the thickness direction so that the trap member loading port 57 can be sealed. In addition, a knob 67 is provided on the upper surface of the head 65 so as to make it easier to grip the trap member 60. FIG. 3 schematically shows a cross-sectional structure of the above-described tissue excision piece collecting tool 50. For the members or regions shown in FIG. 3 that are already shown in FIG. 2 (A) or FIG. 2 (B), the same reference numerals as those used in FIG. 2 (A) or FIG. 2 (B) The explanation is omitted by appending.

In the present embodiment, as shown, the main body member 51 is constituted by a total of three members: a tubular portion 52, a first connector portion 53, and a second connector portion 54. In order to increase the productivity, the cylindrical portion 52 is formed by joining two members, that is, one and the other when the illustrated cylindrical portion 52 is bisected at the center in the longitudinal direction are separated from each other. They can be made as members and joined together to form a joint. Further, the collar 59 can be formed integrally with the tubular portion 52, or can be made as a separate member from the tubular portion 52 and then joined to the tubular portion 52.

At the center in the longitudinal direction on the inner surface of the cylindrical portion 52, the filter portion 63 is guided to a predetermined position so that the filter portion 63 is arranged at a predetermined position when the trap member 60 is loaded on the main body member 51. It is preferable to form a guide groove 52b. The guide groove 52b may be a single curved groove or a plurality of grooves arranged in the inner circumferential direction of the cylindrical portion 52. When the guide groove 52b is formed as a single groove, the tissue excision piece is not caught by the filter medium 61, but cuts through the gap between the inner peripheral surface of the cylindrical portion 52 and the filter portion 63. It is easy to prevent the piece collecting tool 50 from going outside.

The end of the first connector portion 53 on the side of the tubular portion 52 is inserted into the tubular portion 52. The outer diameter of this end portion is substantially the same as the inner diameter of the cylindrical portion 52, and an airtight material such as an O-ring is provided at the end portion so that one open end of the cylindrical portion 52 can be sealed. 5 3b is installed. In order to regulate the insertion depth into the cylindrical portion 52, it is preferable to form a flange portion 53c that functions as a stopper.

The second connector section 54 has the same shape and size as the first connector section 53. In FIG. 3, an airtight material attached to the end of the second connector portion 54 on the tubular portion 52 side is indicated by reference numeral 54b. Further, a flange portion functioning as a stopper is indicated by reference numeral 54c.

In the trap member 60 of the present embodiment, the second holding part 63 b, the head part 65, and the knob part 67 of the filter part 63 are formed into a single body, and the first holding part 63 a is necessary It is manufactured as a member different from the second holding portion 63 b so that the filter medium 61 can be exchanged according to the conditions. The first holding portion 63 a and the second holding portion 63 b are provided with engagement portions (not shown) that can engage with each other, and the filter member 61 is sandwiched therebetween. By engaging the engaging portion on the first holding portion 63 a side and the engaging portion on the second holding portion 63 b side below, the filter medium 61 is stably held. In FIG. 3, an opening formed at the center of the first holding portion 63 a is indicated by reference numeral OP 1, and an opening formed at the center of the second holding portion 63 b is indicated by OP 2. Indicated by.

When the tissue excision piece collecting tool 50 having the above-described appearance and structure is used, the trap member 60 in which the filter medium 61 is sandwiched by the filter part 63 is moved from the filter part 63 side to the trap member loading port 57. Is loaded into the main body member 51 through. Since the knob portion 67 is formed on the trap member 60, the trap member 60 can be easily loaded into the main body member 51 by holding the knob portion 67 with one hand.

As shown in FIG. 4, when the trap member 60 is loaded in the main body member 51, the trap member loading port 57 is sealed by the head portion 65, and the internal space 52a is closed. A flow path 55 (see FIG. 2A or FIG. 2B) is formed by the through holes 53 a and 54 a and the lower surface of the head 65. Further, as a result of the filter portion 63 being guided by the guide groove 52 b and being arranged at a predetermined position, the filter medium 61 is located substantially at the center of the tubular portion 52. In other words, the filter section 63 (filter medium 61) is disposed so as to cross the flow path 55 at the center of the flow path 55.

As a result, when the tissue excision is transferred from the discharge channel to the conduit 30 (see FIG. 1), the tissue excision is captured by the filter medium 61. Then, by removing the trap member 60 that has captured the tissue excision piece from the main body member 51, the tissue excision piece can be collected.

The trap member 60 is mainly composed of a frictional force acting between the inner peripheral surface of the collar 59 and the outer peripheral surface of the head portion 65, and suction generated by the negative pressure generator 40 (see FIG. 1). It is fixed to the main body member 51 by force. Since these frictional force and suction force are relatively weak, even with the negative pressure generator 40 running, simply pull the trap member 60 in a predetermined direction by holding the knob 67 with one hand. The trap member 60 can be easily removed from the main body member 51. When the trap member 60 is removed from the main body member 51 while the negative pressure generator 40 is operated, the negative pressure in the discharge channel is released, so that blood or the like flowing from the discharge channel to the conduit 30 is released. Transfer of bodily fluids, etc. is stopped, and blood, bodily fluids, etc. do not leak from the trap member loading port 57.

If necessary, the cap member 70 shown in FIG. 5 may be attached to the trap member loading port 57. The cap member 70 can have a shape obtained by removing the filter portion 63 from the trap member 60. By attaching the cap member 70, unnecessary tissue excision pieces that do not need to be captured, such as gastrointestinal tract contents, can be transferred along the second conduit 34 (tissue excision piece collection device 50 and negative pressure). It can be transferred by the above-mentioned suction force to the above-mentioned container arranged between the generator 40).

In the tissue excision piece collecting tool 50 described above, the outer diameter of the tubular portion 52 (excluding the region where the collar 59 is formed) in the main body member 51 is the same as the outer diameter of the conduit 30. It works well even if it is about the same size, so miniaturization is easy.

Further, the loading of the trap member 60 into the main body member 51 and the removal of the trap member 60 from the main body member 51 can be easily performed with one hand. Therefore, the operation is simple.

Further, after capturing the tissue excision piece by the filter section 63 (filter medium 61), the trap member 60 is removed from the main body member 51, and is directly placed in a tissue fixing container containing a tissue fixing agent, which will be described later. Fixation is possible simply by inserting, and it is easy to fix the collected tissue excision pieces. Further, by sequentially replacing the trap member 60, a plurality of tissue excision pieces can be continuously collected.

The tissue excision piece collecting tool of the present invention exhibiting such technical effects basically has a tubular main body member and a trap member loaded in the main body member. It is not limited to. Hereinafter, each component will be described in detail with reference to the reference numerals used in FIGS. 1 to 5 as appropriate.

(A) Body material

The body member 51 is preferably made of synthetic resin from the viewpoint of easy processing. In addition, after the target tissue excision is captured by the filter section 63 (filter medium 61), unnecessary tissue excision is prevented from being further captured.

0 From this point, it is preferable that at least a portion is made of a transparent material so that the force of capturing the tissue excision by the filter section 63 (filter medium 61) can be visually recognized from the outside. From such a viewpoint, the main body member 51 is preferably made of a transparent resin such as a polystyrene resin, a polycarbonate resin, an acrylic resin, a polyvinyl chloride resin, and a polyethylene terephthalate resin. Although the workability is inferior to that of the synthetic resin, the main body member 51 can be made of glass.

The main body member 51 only needs to have a flow passage 55 formed therein when the trap member 60 is loaded, and its outline shape can be appropriately selected. When the cylindrical portion 52 is formed in a cylindrical shape (excluding the region where the collar 59 is formed) as in the above-described embodiment, the length is approximately 50 to 100 mm. It is practically preferable that the outer diameter is within the range of 10 to 50 mm.

Also, the cross-sectional shape of the internal space 52 a of the cylindrical portion 52 (the cross-sectional shape in the direction perpendicular to the flow-down direction in the flow passage 55) can be appropriately selected. When the cross-sectional shape is circular (excluding the region where the trap member loading port 57 is formed), it is preferable that the diameter is approximately in the range of 5 to 45 mm.

The outer diameter of each of the first connector part 53 and the second connector part 54 attached to the cylindrical part 52 (the outer diameter of the part to be inserted and connected to the first conduit 32 or the second conduit 34) Is appropriately selected according to the inner diameter of the first conduit 32 or the second conduit 34. It is preferable that the force is approximately in the range of 5 to 15 mm. Further, the protruding length from the tubular portion 52 is such that the first connector portion 53 or the second connector portion 54 is not connected to the first conduit 32 or the second conduit 3 while the tissue excision piece collecting tool 50 is in use. It is preferable to set the value within a range of about 5 to 2 O mm so that the value does not deviate from 4 by mistake.

In order to improve the insertability into the first conduit 32 or the second conduit 34 and to improve the airtightness, the outer diameter of the tip of each of the first connector portion 53 and the second connector portion 54 must be adjusted. The inner diameter of the first conduit 32 or the second conduit 34 is slightly smaller than that of the first conduit 32 or the second conduit 34. A first area slightly larger than the inner diameter of the first pipe 32 and a second area slightly larger than the inner diameter of the first pipe 32 or the second pipe 34 and slightly smaller than the outer diameter of the first area. It is preferable to set the areas in this order! / ,.

Airtight material 5 3b, 5 4b provided in first connector section 53 or second connector section 54 Can be made of an elastic material such as isoprene rubber, butyl rubber, and natural rubber.

Note that the first connector portion 53 and the second connector portion 54 in the above-described embodiment respectively function as a material for the first conduit 32 or the second conduit 34. In place of these connectors S 53 and 54, a member having a through hole formed as a female material for the first conduit 32 or the second conduit 34 is replaced with It can also be used as the 1 connector section or the 2nd connector section.

The trap member loading port 57 formed in the cylindrical portion 52 has such a shape that the filter portion 63 can be inserted into the cylindrical portion 52 and can be hermetically sealed by the head portion 65. It can be appropriately selected according to the shapes of the filter section 63 and the head section 65. If each of the trap member loading port 57 and the head portion 65 has a circular shape in plan view, loading of the trap member 60 into the main body member 51 becomes easy. The size of the trap member loading port 57 can be appropriately selected according to the size of the head 65. The main body member 51 can be distributed in a state where it is assembled in a predetermined shape in advance, or a cylindrical portion so that the user can select an arbitrary combination when using the tissue excision piece collecting tool 50. 52, the first connector section 53, the second connector section 54, and the roller 59 can be distributed separately.

(B) Trap member

The filter part 63, the head part 65, and the knob part 67 of the trap member 60 are integrally formed except for one of the first holding part 63a and the second holding part 63b. It is possible. Of course, after each part is manufactured as a separate member, these members are joined by an ultrasonic fusion method, a heat fusion method, an adhesive, or the like, or are integrated by fitting and screwing to form a trap member 6. It is also possible to assemble to zero.

Further, the filter section 63, the head section 65, and the knob section 67 are provided separately so that the user can select an arbitrary combination when using the tissue excision piece collection tool 50. It can also be distributed as a member.

The filter medium 61 is always provided on the trap member 6 °. Similar to the above, the filter medium 61 can be distributed as a member separate from the trap member 60.

Except for the filter medium 61, the trap member 60 is easy to process and resistant to the tissue fixing agent described later.

Two From the viewpoint of having, it is preferable to use a synthetic resin such as a polystyrene resin, a polycarbonate resin, a polyvinyl chloride resin, or a polyethylene terephthalate resin. If necessary, the knob portion 67 can be colored. By coloring the knobs 67 of the plurality of trap members 60 with different colors, it becomes possible to classify the captured tissue excision pieces by the color of the knobs 67. Although the workability is inferior to that of the synthetic resin, the trap member 60 can be made of glass.

The filter medium 61 is not particularly limited as long as it allows gas and liquid (blood, body fluid, liquid ejected from a water supply channel, etc.) to pass therethrough, and can capture a piece of tissue. It is preferable that the mesh is made of a fibrous material such as polyester fiber and cotton yarn.

The size of the region of the filter medium 61 that is exposed without being covered by the first holding portion 63 a and the second holding portion 63 b is set to a size large enough to capture a tissue excision piece. Further, it is preferable that the opening in the filter medium 61 is about 0.1 to 1.5 mm. If the aperture is smaller than the above range, clogging is likely to occur due to, for example, residues in the body cavity, and if clogging occurs, suction may not be possible. If the aperture is larger than the above range, a necessary tissue excision piece may not be captured.

The surface of the filter medium 61 facing the first conduit 32 is formed into a concave shape that is recessed toward the second conduit 34 (negative pressure generator 40) when at least the tissue excision piece collecting tool 50 is used. Preferably, it is attached to the filter section 63. By attaching the filter medium 61 to the filter section 63 in a relaxed state, the above-described shape can be easily obtained.

By forming the filter medium 61 into the above-described shape, it is easy to remove the trap member 60 from the main body member 51 while the captured tissue excision piece is held by the filter unit 63 (filter medium 61). It is preferable that a mark for designating the orientation of the trap member 60 at the time of loading is provided at a desired position of the trap member 60 as necessary.

Instead of attaching the filter medium 61 to the filter section 63 in the above-described shape, the periphery of each of the first holding section 63 a and the second holding section 63 b (means an area located around the filter medium 61) ) Can be made thicker, and a concave portion for holding the captured tissue excision piece can be formed by the peripheral portion and the filter medium 61.

If there is no need to consider replacing the filter media 61, replace the filter unit 63 with the first holding unit 63. The filter member 61 may be formed as one member without being divided into a and the second holding portion 63 b, and the filter member 61 may be joined to the filter portion.

In addition, as the filter medium 61, a synthetic resin plate or a metal plate having a large number of through holes can be used. When the filter medium 61 is a synthetic resin plate or a metal plate, the first holding section 63 a and the second holding section 63 b are omitted in supporting the filter medium 61, and the head section 65 is formed. It is also possible to hold the filter medium 61 on the lower surface. In this case, the filter medium 61 becomes the filter section 63.

The head portion 65 preferably has a shape projecting around the filter portion 63 in plan view, and has a shape corresponding to the contour shape and size of the trap member loading port 57 in plan view. It is preferable to make the size large.

Further, it is preferable to provide the head portion 65 with an airtight material 65a as in the above-described embodiment. By providing the airtight material 65a, airtightness with the trap member loading port 57 can be improved. The hermetic material 65a can be made of an elastic material such as isoprene rubber, butyl rubber, and natural rubber. In loading the trap member 60 into the main body member 51, a sealant such as silicone grease may be applied to the outer peripheral surface of the head portion 65 as necessary.

The knob 67 provided on the head 65 is used to load the trap member 60 into the main body member 51 and remove the trap member 60 from the main body member 51. It is intended to allow 7 to be held by one hand, and its shape and size can be selected as appropriate.

(C) Cap member

As described above, the cap member 70 is attached to the trap member loading port 57 when the trap member 60 is not loaded in the main body member 51, and seals the trap member loading port 57. In addition, it is possible to adopt a shape excluding the above-described trap member 60 and the filter portion 63. The cap member 70 is also made of a synthetic resin such as a polystyrene resin, a polycarbonate resin, a polychlorinated vinyl resin, or a polyethylene terephthalate resin, from the viewpoint of easy processing and resistance to a tissue fixing agent described later. preferable. Although the workability is inferior to that of the synthetic resin, the cap member 70 can be made of glass.

Four Embodiment of Tissue Fixing Container and Tissue Fixing Device of the Present Invention>

FIG. 6 is an exploded perspective view schematically showing a state in which the trap member 60 after capturing the tissue excision piece 85 is accommodated in the tissue fixing container 90 of the present embodiment. Of the members shown in FIG. 6, members already shown in FIG. 2 (A) are denoted by the same reference numerals as those used in FIG. 2 (A), and description thereof is omitted.

The illustrated tissue-fixing container 90 is a bottle-shaped object having a mouth 91 at one end, and the tissue-fixing container 90 has an internal volume capable of accommodating the tissue excision piece 85 together with the filter portion 63. have. The mouth 91 has a shape and a size corresponding to the shape and the size of the head portion 65 in a plan view. An overhang portion 93 is formed to be able to lock the lower surface of the device.

Such a tissue fixing container 90 is made of a transparent material that is resistant to a tissue fixing agent and that allows the visible tissue excision pieces to be visible, such as polystyrene resin, polycarbonate resin, and polysalt. It is preferable to use a transparent resin such as a vinyl resin or a polyethylene terephthalate resin, glass, or the like.

To fix the tissue excision piece 85, an appropriate amount of a tissue fixing agent, for example, a 20% formalin solution is put in a tissue fixing container 90 in advance, and then the trap member 60 capturing the tissue excision piece 85 is filtered into the filter section 6. It can be performed by inserting the tissue fixing container 90 from the third side. At this time, the filter portion 63 is inserted below the overhang portion 93. As shown in FIG. 7, since the port 91 has the above-described shape and size, when the trap member 60 is inserted into the tissue fixing container 90, the port 91 becomes concave. It is sealed by the pad section 65. As shown in the drawing, under the condition that the lower surface of the head portion 65 is locked by the overhang portion 93, the tissue is arranged so that the lower end of the filter portion 63 and the bottom surface of the tissue fixing container 90 are in contact with each other. By selecting the depth of the fixation container 90, it is easy to prevent the tissue excision piece 85 from dropping from the trap member 60 to the bottom of the tissue fixation container 90 during storage. As a result, it becomes easy to reliably pull up the tissue excision piece 85 from the tissue fixing container 90 at the time of pathological tissue diagnosis.

By using the above-mentioned tissue fixing container 90, it is possible to fix the tissue excision piece 85 without removing it from the trap member 60, so that the tissue excision piece 85 is crushed in the fixing process. The danger of accidents can be extremely reduced. In addition, a tissue excision piece collection tool 5 0 The removal of the trap member 60 from the (body member 51) can be performed with one hand as described above, and the insertion of the trap member 60 into the tissue fixing container 90 can also be performed with one hand. Since it is possible, the fixing work can be performed quickly and easily.

Further, when performing a pathological tissue diagnosis, the tissue excision piece 85 can be taken out together by simply removing the trap member 60 from the tissue fixing container 90, so that only the tissue excision piece 85 is tissue-free. It is simpler than taking out from the fixing container.

The trap member 60 can be used not only as a component of the tissue excision piece collecting tool 50 described above, but also as a component of a tissue fixing tool. The trap member 60 and the tissue fixing container 90 corresponding to the trap member 60 constitute a set of tissue fixing tools 100. Industrial applicability

As described above, according to the present invention, there is provided a tissue excision piece collection tool which can be easily miniaturized, can be operated with one hand, and can easily fix a collected tissue excision piece, and its constituent members. You. By sequentially replacing the trap member, it is possible to continuously collect a plurality of tissue excision pieces. Further, according to the present invention, there is also provided a tissue fixing container and a tissue fixing device that can easily fix the tissue excision pieces collected by the tissue excision piece collection tool.

As a result, it becomes easy to collect and fix the tissue excision more quickly and reliably.

Claims

The scope of the claims

1. A tissue excision piece that is arranged in a conduit connecting the discharge channel of the endoscope and a negative pressure generator for creating a negative pressure in the discharge channel, and is transferred from the discharge channel into the conduit. A collection tool for collecting

A tubular body member, and a trap member loaded into the body member,

The main body member has a flow passage that is a section of the conduit, and a trap member loading port for loading the trap member.

The trap member has a filter unit on which a filter medium for capturing the tissue excision piece is disposed, and a head unit connected to the filter unit,

When the trap member is loaded in the main body member, the filter portion is disposed so as to cross the flow passage, and the trap member loading port is sealed by the head portion,

A tissue excision piece retrieving tool that is free to load the trap member into the main body member and remove the trap member from the main body member.

2. The pipe is divided into a first pipe on the discharge channel side and a second pipe on the negative pressure generator side, with the location of the main body member as a boundary,

The main body member has a first connector portion connected to the first conduit and a second connector portion connected to the second conduit, and the first connector portion and the second connector portion 2. The tissue excision piece collecting device according to claim 1, wherein each of the insides constitutes a part of the flow passage.

3. The tissue excision piece collecting tool according to claim 1, wherein the main body member has a guide groove for guiding the filter portion to a predetermined position when the trap member is loaded.

4. The filter unit has a first holding unit having an opening at the center, and a second holding unit having an opening at the center corresponding to the opening, and the first holding unit and the second holding unit The tissue excision piece collection device according to any one of claims 1 to 3, which can hold the filter medium.

5. The tissue excision piece collection device according to any one of claims 1 to 4, wherein the filter medium is arranged in a relaxed state on the filter portion.

6. Load a trap member in which the filter medium is disposed in the filter portion into the main body member

7 The tissue excision piece collection tool according to any one of claims 1 to 5, wherein the filter medium can be visually recognized when the tissue resection is performed.

7. The apparatus according to claim 1, further comprising a cap member that is mounted on the trap member loading port when the trap member is not loaded on the main body member and that can seal the trap member loading port. 7. The tissue excision piece collecting device according to any one of to 6).

8. The body member for a tissue excision piece retrieving tool according to any one of claims 1, 2, 3, and 6.

9. The trapping member for a tissue excision piece retrieving device according to claim 1, 4, or 5.

10. A tissue fixing container which can be used for fixing a tissue excision piece collected by the tissue excision piece recovery tool according to any one of claims 1 to 7 or the trap member according to claim 9. hand,

The filter has an internal volume capable of accommodating the tissue excision pieces captured by the trap member together with the filter section, and is sealed by the head section when the tissue excision pieces are accommodated together with the filter section. Tissue fixation container that can be.

11. A tissue fixing device comprising the trap member according to claim 1, 4 or 5, and the tissue fixing container according to claim 10.

12. A method for collecting a tissue excision piece using the tissue excision piece collection tool according to any one of claims 1 to 7.

13. The method for fixing a tissue excision piece using the tissue fixing device according to claim 11.