WO2004074767A1 - Procede et appareil pour l'analyse spectrale d'images - Google Patents

Procede et appareil pour l'analyse spectrale d'images Download PDF

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Publication number
WO2004074767A1
WO2004074767A1 PCT/US1992/001171 US9201171W WO2004074767A1 WO 2004074767 A1 WO2004074767 A1 WO 2004074767A1 US 9201171 W US9201171 W US 9201171W WO 2004074767 A1 WO2004074767 A1 WO 2004074767A1
Authority
WO
WIPO (PCT)
Prior art keywords
interferometer
light
scene
pixel
scanned
Prior art date
Application number
PCT/US1992/001171
Other languages
English (en)
Inventor
Dario Cabib
Zvi Friedman
Stephen G. Lipson
Robert A. Buckwald
Original Assignee
Dario Cabib
Zvi Friedman
Lipson Stephen G
Buckwald Robert A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dario Cabib, Zvi Friedman, Lipson Stephen G, Buckwald Robert A filed Critical Dario Cabib
Priority to US08/575,191 priority Critical patent/US5936731A/en
Priority to US08/886,293 priority patent/US6018587A/en
Priority to US08/942,122 priority patent/US6198532B1/en
Priority to US09/752,833 priority patent/US6419361B2/en
Publication of WO2004074767A1 publication Critical patent/WO2004074767A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/88—Image or video recognition using optical means, e.g. reference filters, holographic masks, frequency domain filters or spatial domain filters
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J2003/2866—Markers; Calibrating of scan

Definitions

  • the total time spent summed over all the detectors on a particular pixel is the same, nT/m2.
  • the energy seen by every detector at any time is of the order of 1 /n of the total because the wavelength resolution is 1 /n of the range
  • the energy is of the order of unity because the modulating fuction is a sinusoidal (Michelson) or similar periodic function (low finesse Airy function with Fabry-Perot) whose average over many periods is 50%. This results in an improved signal to noise ratio, of the order of n/2.
  • optical path differences between the two arms which vary linearly with the incident angle.
  • the differences are proportional to the angular deviation from the optical axis.
  • the scanner 73 scans the field of view.
  • Reflector 75 with the microscope system, move together along the optical axis to provide scanning of the OPD in synchronization with the scanner 73, as described above with respect to Fig. 5.

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

L'invention porte sur un procédé et sur un appareil d'analyse d'une image optique d'une scène permettant de déterminer l'intensité spectrale de chaque pixel de celle-ci. Ce procédé consiste à collecter la lumière incidente provenant de la scène (20); balayer la lumière incidente (22); faire passer la lumière balayée dans un interféromètre (24) qui émet une lumière modulée correspondant à un ensemble prédéterminé de combinaisons linéaires de l'intensité spectrale de la lumière émise par chaque pixel; focaliser la lumière émise par l'interféromètre sur un réseau de détecteurs (26) et traiter la sortie du réseau de détecteurs (28) afin de déterminer l'intensité spectrale de chaque pixel.
PCT/US1992/001171 1991-02-21 1992-02-19 Procede et appareil pour l'analyse spectrale d'images WO2004074767A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US08/575,191 US5936731A (en) 1991-02-22 1995-12-20 Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting
US08/886,293 US6018587A (en) 1991-02-21 1997-07-01 Method for remote sensing analysis be decorrelation statistical analysis and hardware therefor
US08/942,122 US6198532B1 (en) 1991-02-22 1997-10-01 Spectral bio-imaging of the eye
US09/752,833 US6419361B2 (en) 1991-02-22 2001-01-03 Spectral bio-imaging of the eye

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL9732891A IL97328A (en) 1991-02-22 1991-02-22 Method and apparatus for spectral analysis of images
IL97328 1991-02-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US08/392,019 Continuation-In-Part US5539517A (en) 1991-02-21 1995-02-21 Method for simultaneously measuring the spectral intensity as a function of wavelength of all the pixels of a two dimensional scene

Publications (1)

Publication Number Publication Date
WO2004074767A1 true WO2004074767A1 (fr) 2004-09-02

Family

ID=11062134

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1992/001171 WO2004074767A1 (fr) 1991-02-21 1992-02-19 Procede et appareil pour l'analyse spectrale d'images

Country Status (2)

Country Link
IL (1) IL97328A (fr)
WO (1) WO2004074767A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9418414B2 (en) 2012-05-30 2016-08-16 Panasonic Intellectual Property Management Co., Ltd. Image measurement apparatus, image measurement method and image measurement system
US9430846B2 (en) 2013-04-19 2016-08-30 Ge Aviation Systems Llc Method of tracking objects using hyperspectral imagery
WO2022126198A1 (fr) * 2020-12-18 2022-06-23 Rapid Phenotyping Pty Limited Procédé de traitement de signal d'interférométrie et interféromètre associé
CN116774222A (zh) * 2023-08-23 2023-09-19 中国电子科技集团公司第十四研究所 一种机电扫结合的多模式马赛克成像方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684379A (en) * 1968-10-09 1972-08-15 Nationale D Etudes De Rech Aer Interferometric device
US4523846A (en) * 1982-09-10 1985-06-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Integrated optics in an electrically scanned imaging Fourier transform spectrometer
US4976542A (en) * 1988-07-25 1990-12-11 Washington University Digital array scanned interferometer
US5059027A (en) * 1989-04-11 1991-10-22 Wisconsin Alumni Research Foundation Spatial heterodyne spectrometer and method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684379A (en) * 1968-10-09 1972-08-15 Nationale D Etudes De Rech Aer Interferometric device
US4523846A (en) * 1982-09-10 1985-06-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Integrated optics in an electrically scanned imaging Fourier transform spectrometer
US4976542A (en) * 1988-07-25 1990-12-11 Washington University Digital array scanned interferometer
US5059027A (en) * 1989-04-11 1991-10-22 Wisconsin Alumni Research Foundation Spatial heterodyne spectrometer and method

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9418414B2 (en) 2012-05-30 2016-08-16 Panasonic Intellectual Property Management Co., Ltd. Image measurement apparatus, image measurement method and image measurement system
US9430846B2 (en) 2013-04-19 2016-08-30 Ge Aviation Systems Llc Method of tracking objects using hyperspectral imagery
WO2022126198A1 (fr) * 2020-12-18 2022-06-23 Rapid Phenotyping Pty Limited Procédé de traitement de signal d'interférométrie et interféromètre associé
CN116774222A (zh) * 2023-08-23 2023-09-19 中国电子科技集团公司第十四研究所 一种机电扫结合的多模式马赛克成像方法
CN116774222B (zh) * 2023-08-23 2023-11-14 中国电子科技集团公司第十四研究所 一种机电扫结合的多模式马赛克成像方法

Also Published As

Publication number Publication date
IL97328A0 (en) 1992-05-25
IL97328A (en) 1996-07-23

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