WO2004071267A3 - Diagnosis of colorectal cancer by detection of nicotinamide n-methyltransferase in a stool sample - Google Patents
Diagnosis of colorectal cancer by detection of nicotinamide n-methyltransferase in a stool sample Download PDFInfo
- Publication number
- WO2004071267A3 WO2004071267A3 PCT/EP2004/001152 EP2004001152W WO2004071267A3 WO 2004071267 A3 WO2004071267 A3 WO 2004071267A3 EP 2004001152 W EP2004001152 W EP 2004001152W WO 2004071267 A3 WO2004071267 A3 WO 2004071267A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diagnosis
- colorectal cancer
- nicotinamide
- methyltransferase
- detection
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
Abstract
The present invention relates to the diagnosis of colorectal cancer. It discloses the use of nicotinamide Nmethyltransferase NNMT in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a stool sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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EP03002651.2 | 2003-02-11 | ||
EP03002651 | 2003-02-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004071267A2 WO2004071267A2 (en) | 2004-08-26 |
WO2004071267A3 true WO2004071267A3 (en) | 2004-10-21 |
Family
ID=32864921
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2004/001152 WO2004071267A2 (en) | 2003-02-11 | 2004-02-09 | Diagnosis of colorectal cancer by detection of nicotinamide n-methyltransferase in a stool sample |
Country Status (1)
Country | Link |
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WO (1) | WO2004071267A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006044680A1 (en) * | 2004-10-14 | 2006-04-27 | The Cleveland Clinic Foundation | Methods of detecting colorectal cancer |
WO2007071366A1 (en) * | 2005-12-21 | 2007-06-28 | Roche Diagnostics Gmbh | Method of assessing colorectal cancer by measuring hemoglobin and m2-pk in a stool sample |
US10087449B2 (en) | 2014-04-07 | 2018-10-02 | Shionogi & Co., Ltd. | Pharmaceutical composition for treating chronic kidney disease |
CN106248946A (en) * | 2016-08-19 | 2016-12-21 | 浙江大学 | A kind of enzyme-linked immunologic detecting kit and application thereof |
EP3431609B1 (en) | 2017-07-17 | 2020-02-12 | Masarykova Univerzita | Method of diagnosis of colorectal cancer |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002070742A1 (en) * | 2001-03-01 | 2002-09-12 | Epigenomics Ag | Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylatoin status of the genes |
-
2004
- 2004-02-09 WO PCT/EP2004/001152 patent/WO2004071267A2/en active Search and Examination
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002070742A1 (en) * | 2001-03-01 | 2002-09-12 | Epigenomics Ag | Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylatoin status of the genes |
Non-Patent Citations (5)
Title |
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AHLQUIST D A: "FECAL OCCULT BLOOD TESTING FOR COLORECTAL CANCER CAN WE AFFORD TO DO THIS?", GASTROENTEROLOGY CLINICS OF NORTH AMERICA, XX, XX, vol. 26, no. 1, March 1997 (1997-03-01), pages 41 - 55, XP008021412 * |
AOYAMA K ET AL: "Nicotinamide-N-methyltransferase is higher in the lumbar cerebrospinal fluid of patients with Parkinson's disease.", NEUROSCIENCE LETTERS. 26 JAN 2001, vol. 298, no. 1, 26 January 2001 (2001-01-26), pages 78 - 80, XP002237184, ISSN: 0304-3940 * |
OKAMURA A ET AL: "INCREASED HEPATIC NICOTINAMIDE N-METHYLTRANSFERASE ACTIVITY AS A MARKER OF CANCER CACHEXIA IN MICE BEARING COLON 26 ADENOCARCINOMA", JAPANESE JOURNAL OF CANCER RESEARCH, JAPANESE CANCER ASSOCIATION, TOKYO, JP, vol. 89, no. 6, June 1998 (1998-06-01), pages 649 - 656, XP009008878, ISSN: 0910-5050 * |
PARSONS RICHARD B ET AL: "Expression of nicotinamide N-methyltransferase (E.C. 2.1.1.1) in the Parkinsonian brain", JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, vol. 61, no. 2, February 2002 (2002-02-01), pages 111 - 124, XP009033873, ISSN: 0022-3069 * |
SIEG ANDREAS ET AL: "Detection of colorectal neoplasms by the highly sensitive hemoglobin-haptoglobin complex in feces", INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, vol. 14, no. 6, December 1999 (1999-12-01), pages 267 - 271, XP002288706, ISSN: 0179-1958 * |
Also Published As
Publication number | Publication date |
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WO2004071267A2 (en) | 2004-08-26 |
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