WO2004067759A3 - Replication of nucleic acid arrays - Google Patents

Replication of nucleic acid arrays Download PDF

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Publication number
WO2004067759A3
WO2004067759A3 PCT/GB2004/000375 GB2004000375W WO2004067759A3 WO 2004067759 A3 WO2004067759 A3 WO 2004067759A3 GB 2004000375 W GB2004000375 W GB 2004000375W WO 2004067759 A3 WO2004067759 A3 WO 2004067759A3
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WO
WIPO (PCT)
Prior art keywords
nucleic acids
nucleic acid
replication
acid arrays
hybridised
Prior art date
Application number
PCT/GB2004/000375
Other languages
French (fr)
Other versions
WO2004067759A2 (en
Inventor
Alessandra Bossi
Sergey Anatoliyovich Piletsky
Olena Volodimirivna Piletska
Philip James Warner
Anthony Peter Francis Turner
Original Assignee
Univ Cranfield
Alessandra Bossi
Sergey Anatoliyovich Piletsky
Olena Volodimirivna Piletska
Philip James Warner
Anthony Peter Francis Turner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cranfield, Alessandra Bossi, Sergey Anatoliyovich Piletsky, Olena Volodimirivna Piletska, Philip James Warner, Anthony Peter Francis Turner filed Critical Univ Cranfield
Priority to GB0516777A priority Critical patent/GB2413555A/en
Publication of WO2004067759A2 publication Critical patent/WO2004067759A2/en
Publication of WO2004067759A3 publication Critical patent/WO2004067759A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Looms (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A method of producing arrays of nucleic acids corresponding to a first set of nucleic acids immobilised on a first solid support (master array) includes furnishing on said first set of nucleic acids a second set of nucleic acids, each nucleic acid of the second set having at least a portion which is complementary to at least a portion of respective nucleic acid of the first set and being hybridised to it thereby. This may involve contact with a solution containing a mixture of nucleic acids, or synthesis using the first nucleic acids as primers and templates. The second set of nucleic acids are immobilised to a second solid support, either before or while they are hybridised to the first set of nucleic acids. Separation of the first and second solid supports provides said first support bearing the master array and said second support bearing a complementary array.
PCT/GB2004/000375 2003-01-29 2004-01-29 Replication of nucleic acid arrays WO2004067759A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0516777A GB2413555A (en) 2003-01-29 2004-01-29 Replication of nucleic acid arrays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0302058.3A GB0302058D0 (en) 2003-01-29 2003-01-29 Replication of nucleic acid arrays
GB0302058.3 2003-01-29

Publications (2)

Publication Number Publication Date
WO2004067759A2 WO2004067759A2 (en) 2004-08-12
WO2004067759A3 true WO2004067759A3 (en) 2004-11-18

Family

ID=9952050

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/000375 WO2004067759A2 (en) 2003-01-29 2004-01-29 Replication of nucleic acid arrays

Country Status (2)

Country Link
GB (2) GB0302058D0 (en)
WO (1) WO2004067759A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11965213B2 (en) 2019-05-30 2024-04-23 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample

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EP1763589A1 (en) * 2004-06-30 2007-03-21 RiNA Netzwerk RNA-Technologien GmbH Blueprint biochips
GB2440209A (en) * 2006-07-18 2008-01-23 Univ Cranfield Nucleic acid arrays replication
ITBO20070627A1 (en) * 2007-09-14 2009-03-15 Twof Inc METHOD FOR THE PREPARATION OF MICROARRAY DNA WITH HIGH LINEAR DENSITY PROBES
WO2010003132A1 (en) 2008-07-02 2010-01-07 Illumina Cambridge Ltd. Using populations of beads for the fabrication of arrays on surfaces
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
DK2556171T3 (en) 2010-04-05 2015-12-14 Prognosys Biosciences Inc Spatially CODED BIOLOGICAL ASSAYS
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP2647426A1 (en) * 2012-04-03 2013-10-09 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Replication of distributed nucleic acid molecules with preservation of their relative distribution through hybridization-based binding
CN111662960B (en) 2013-06-25 2024-04-12 普罗格诺西斯生物科学公司 Spatially encoded bioanalytical analysis using microfluidic devices
US10597715B2 (en) 2013-12-05 2020-03-24 Centrillion Technology Holdings Methods for sequencing nucleic acids
EP3077430A4 (en) 2013-12-05 2017-08-16 Centrillion Technology Holdings Corporation Modified surfaces
US10391467B2 (en) 2013-12-05 2019-08-27 Centrillion Technology Holdings Corporation Fabrication of patterned arrays
US11060139B2 (en) 2014-03-28 2021-07-13 Centrillion Technology Holdings Corporation Methods for sequencing nucleic acids
DK3901281T3 (en) 2015-04-10 2023-01-23 Spatial Transcriptomics Ab SPATIALLY SEPARATE, MULTIPLEX NUCLEIC ACID ANALYSIS OF BIOLOGICAL SAMPLES
WO2020047004A2 (en) * 2018-08-28 2020-03-05 10X Genomics, Inc. Methods of generating an array
US11519033B2 (en) 2018-08-28 2022-12-06 10X Genomics, Inc. Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
WO2020123320A2 (en) 2018-12-10 2020-06-18 10X Genomics, Inc. Imaging system hardware
US11926867B2 (en) 2019-01-06 2024-03-12 10X Genomics, Inc. Generating capture probes for spatial analysis
US11649485B2 (en) 2019-01-06 2023-05-16 10X Genomics, Inc. Generating capture probes for spatial analysis
EP4025711A2 (en) 2019-11-08 2022-07-13 10X Genomics, Inc. Enhancing specificity of analyte binding
ES2946357T3 (en) 2019-12-23 2023-07-17 10X Genomics Inc Methods for spatial analysis using RNA template ligation
US11732299B2 (en) 2020-01-21 2023-08-22 10X Genomics, Inc. Spatial assays with perturbed cells
US11702693B2 (en) 2020-01-21 2023-07-18 10X Genomics, Inc. Methods for printing cells and generating arrays of barcoded cells
US11898205B2 (en) 2020-02-03 2024-02-13 10X Genomics, Inc. Increasing capture efficiency of spatial assays
US11732300B2 (en) 2020-02-05 2023-08-22 10X Genomics, Inc. Increasing efficiency of spatial analysis in a biological sample
US11891654B2 (en) 2020-02-24 2024-02-06 10X Genomics, Inc. Methods of making gene expression libraries
EP4242325A3 (en) 2020-04-22 2023-10-04 10X Genomics, Inc. Methods for spatial analysis using targeted rna depletion
WO2021237087A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Spatial analysis to detect sequence variants
WO2021236929A1 (en) 2020-05-22 2021-11-25 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
WO2021242834A1 (en) 2020-05-26 2021-12-02 10X Genomics, Inc. Method for resetting an array
WO2021252499A1 (en) 2020-06-08 2021-12-16 10X Genomics, Inc. Methods of determining a surgical margin and methods of use thereof
EP4165207A1 (en) 2020-06-10 2023-04-19 10X Genomics, Inc. Methods for determining a location of an analyte in a biological sample
WO2021263111A1 (en) 2020-06-25 2021-12-30 10X Genomics, Inc. Spatial analysis of dna methylation
US11761038B1 (en) 2020-07-06 2023-09-19 10X Genomics, Inc. Methods for identifying a location of an RNA in a biological sample
US11926822B1 (en) 2020-09-23 2024-03-12 10X Genomics, Inc. Three-dimensional spatial analysis
US11827935B1 (en) 2020-11-19 2023-11-28 10X Genomics, Inc. Methods for spatial analysis using rolling circle amplification and detection probes
EP4121555A1 (en) 2020-12-21 2023-01-25 10X Genomics, Inc. Methods, compositions, and systems for capturing probes and/or barcodes
WO2022256503A1 (en) * 2021-06-03 2022-12-08 10X Genomics, Inc. Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
WO2023034489A1 (en) 2021-09-01 2023-03-09 10X Genomics, Inc. Methods, compositions, and kits for blocking a capture probe on a spatial array

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WO1996001836A1 (en) * 1994-07-07 1996-01-25 Nanogen, Inc. Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
US5795714A (en) * 1992-11-06 1998-08-18 Trustees Of Boston University Method for replicating an array of nucleic acid probes
WO1998044151A1 (en) * 1997-04-01 1998-10-08 Glaxo Group Limited Method of nucleic acid amplification
WO2000027521A1 (en) * 1998-11-06 2000-05-18 Solexa Ltd. A method for reproducing molecular arrays
WO2001032935A2 (en) * 1999-11-02 2001-05-10 Celine Hu Molecular microarrays and methods for production and use thereof
WO2002010450A2 (en) * 2000-08-02 2002-02-07 Surmodics, Inc. Replicable probe array
EP1180548A2 (en) * 2000-07-31 2002-02-20 Agilent Technologies, Inc. Array based methods for synthesizing nucleic acid mixtures

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795714A (en) * 1992-11-06 1998-08-18 Trustees Of Boston University Method for replicating an array of nucleic acid probes
WO1996001836A1 (en) * 1994-07-07 1996-01-25 Nanogen, Inc. Self-addressable self-assembling microelectronic systems and devices for molecular biological analysis and diagnostics
WO1998044151A1 (en) * 1997-04-01 1998-10-08 Glaxo Group Limited Method of nucleic acid amplification
WO2000027521A1 (en) * 1998-11-06 2000-05-18 Solexa Ltd. A method for reproducing molecular arrays
WO2001032935A2 (en) * 1999-11-02 2001-05-10 Celine Hu Molecular microarrays and methods for production and use thereof
EP1180548A2 (en) * 2000-07-31 2002-02-20 Agilent Technologies, Inc. Array based methods for synthesizing nucleic acid mixtures
WO2002010450A2 (en) * 2000-08-02 2002-02-07 Surmodics, Inc. Replicable probe array

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11965213B2 (en) 2019-05-30 2024-04-23 10X Genomics, Inc. Methods of detecting spatial heterogeneity of a biological sample

Also Published As

Publication number Publication date
GB2413555A (en) 2005-11-02
WO2004067759A2 (en) 2004-08-12
GB0516777D0 (en) 2005-09-21
GB0302058D0 (en) 2003-02-26

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