WO2004060379A3 - Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications - Google Patents

Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications Download PDF

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Publication number
WO2004060379A3
WO2004060379A3 PCT/HU2003/000110 HU0300110W WO2004060379A3 WO 2004060379 A3 WO2004060379 A3 WO 2004060379A3 HU 0300110 W HU0300110 W HU 0300110W WO 2004060379 A3 WO2004060379 A3 WO 2004060379A3
Authority
WO
WIPO (PCT)
Prior art keywords
extragenital
nitroimidazole
complications
treatment
prevention
Prior art date
Application number
PCT/HU2003/000110
Other languages
French (fr)
Other versions
WO2004060379A2 (en
Inventor
Marton Milankovits
Original Assignee
Marton Milankovits
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0300010A external-priority patent/HU0300010D0/en
Priority claimed from HU0400015A external-priority patent/HUP0400015A2/en
Application filed by Marton Milankovits filed Critical Marton Milankovits
Priority to AU2003290377A priority Critical patent/AU2003290377A1/en
Publication of WO2004060379A2 publication Critical patent/WO2004060379A2/en
Publication of WO2004060379A3 publication Critical patent/WO2004060379A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compositions having synergistic effective amounts of one or more antibacterial a gents, a nitroimidazole, and/or a sulfonamide with or without an antifungal agent effective against a candida species. The compositions are particularly useful in the treatment of genitourinary infections and their extragenital complications. Vaccination against pathogen microbes of the vagina provides a stronger and longer immune response, than the infection.
PCT/HU2003/000110 2003-01-03 2003-12-30 Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications WO2004060379A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003290377A AU2003290377A1 (en) 2003-01-03 2003-12-30 Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HUP0300010 2003-01-03
HU0300010A HU0300010D0 (en) 2003-01-03 2003-01-03 Pharmaceutical compositions primarily for the treatment of genitourinary infect, ons and their extragenital complications
HU0400015A HUP0400015A2 (en) 2003-12-18 2003-12-18 Pharmaceutical combinations especially for the treatment and prevention of urologigal infections and their extragenital complications
HUP0400015 2003-12-18

Publications (2)

Publication Number Publication Date
WO2004060379A2 WO2004060379A2 (en) 2004-07-22
WO2004060379A3 true WO2004060379A3 (en) 2004-10-14

Family

ID=89981897

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU2003/000110 WO2004060379A2 (en) 2003-01-03 2003-12-30 Pharmaceutical compositions comprising an antibacterial agent nd antifungal agent and a nitroimidazole for the treatment and prevention of genitourinary infections and their extragenital complications

Country Status (2)

Country Link
AU (1) AU2003290377A1 (en)
WO (1) WO2004060379A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1671623A1 (en) * 2004-10-01 2006-06-21 Giuseppe Vrespa Composition for use in the antibacterial and antiinflammatory treatment of the oral cavity
US20070244199A1 (en) * 2006-02-08 2007-10-18 Fasgen Inc. Anti-mycobacterial formulation
WO2024085926A2 (en) * 2022-06-30 2024-04-25 University Of Utah Research Foundation Compositions and methods of treating, preventing or inhibiting a facultative anaerobe infection

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005207A (en) * 1973-08-10 1977-01-25 Saarstickstoff-Fatol Gmbh Synergistic therapeutic composition for the treatment of mycobacterioses
RO80363A2 (en) * 1980-11-08 1983-02-01 Intreprinderea De Antibiotice,Ro VAGINAL POLYACTIVE GEL
GB2154606A (en) * 1984-02-21 1985-09-11 Becton Dickinson Co Selective agent for group a streptococci
GB2187956A (en) * 1986-03-22 1987-09-23 Smith & Nephew Ass Antibacterial and/or antifungal compositions
US4888327A (en) * 1987-02-24 1989-12-19 Alcon Laboratories, Inc. Topical antibiotic compositions
WO1996003135A1 (en) * 1994-07-25 1996-02-08 Milankovits Marton Pharmaceutical compositions, mainly vaginal suppository, containing many different active ingredients
AP598A (en) * 1994-12-20 1997-07-21 Acupharm Pty Limited Metronidazole combinations.
US5707996A (en) * 1995-11-06 1998-01-13 Macleod Pharmaceuticals, Inc. Pharmaceutical solution and methods for preparation thereof
CN1206590A (en) * 1998-09-01 1999-02-03 锦州制药一厂 Shuangzuoxing suppository and ointment
CN1228303A (en) * 1998-03-09 1999-09-15 锦州市制药五厂 Drug composition for curing gynaecological vaginitis
US6350468B1 (en) * 1997-12-17 2002-02-26 Axcan Pharma Inc. Double capsule for the administration of active principles in multiple therapies
US20030073646A1 (en) * 1997-01-22 2003-04-17 Marton Milankovits Pharmaceutical compositions primarily for the treatment of genitourinary infections

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005207A (en) * 1973-08-10 1977-01-25 Saarstickstoff-Fatol Gmbh Synergistic therapeutic composition for the treatment of mycobacterioses
RO80363A2 (en) * 1980-11-08 1983-02-01 Intreprinderea De Antibiotice,Ro VAGINAL POLYACTIVE GEL
GB2154606A (en) * 1984-02-21 1985-09-11 Becton Dickinson Co Selective agent for group a streptococci
GB2187956A (en) * 1986-03-22 1987-09-23 Smith & Nephew Ass Antibacterial and/or antifungal compositions
US4888327A (en) * 1987-02-24 1989-12-19 Alcon Laboratories, Inc. Topical antibiotic compositions
WO1996003135A1 (en) * 1994-07-25 1996-02-08 Milankovits Marton Pharmaceutical compositions, mainly vaginal suppository, containing many different active ingredients
AP598A (en) * 1994-12-20 1997-07-21 Acupharm Pty Limited Metronidazole combinations.
US5707996A (en) * 1995-11-06 1998-01-13 Macleod Pharmaceuticals, Inc. Pharmaceutical solution and methods for preparation thereof
US20030073646A1 (en) * 1997-01-22 2003-04-17 Marton Milankovits Pharmaceutical compositions primarily for the treatment of genitourinary infections
US6350468B1 (en) * 1997-12-17 2002-02-26 Axcan Pharma Inc. Double capsule for the administration of active principles in multiple therapies
CN1228303A (en) * 1998-03-09 1999-09-15 锦州市制药五厂 Drug composition for curing gynaecological vaginitis
CN1206590A (en) * 1998-09-01 1999-02-03 锦州制药一厂 Shuangzuoxing suppository and ointment

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 198333, Derwent World Patents Index; Class B05, AN 1983-739037, XP002283103 *
DATABASE WPI Section Ch Week 199924, Derwent World Patents Index; Class B02, AN 1999-278194, XP002283105 *
DATABASE WPI Section Ch Week 200001, Derwent World Patents Index; Class B02, AN 2000-000125, XP002283104 *

Also Published As

Publication number Publication date
WO2004060379A2 (en) 2004-07-22
AU2003290377A1 (en) 2004-07-29
AU2003290377A8 (en) 2004-07-29

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