WO2004050896A8 - A method and therapeutic platelets - Google Patents

A method and therapeutic platelets

Info

Publication number
WO2004050896A8
WO2004050896A8 PCT/US2003/038133 US0338133W WO2004050896A8 WO 2004050896 A8 WO2004050896 A8 WO 2004050896A8 US 0338133 W US0338133 W US 0338133W WO 2004050896 A8 WO2004050896 A8 WO 2004050896A8
Authority
WO
WIPO (PCT)
Prior art keywords
preservative
biological sample
loaded
solution
protein
Prior art date
Application number
PCT/US2003/038133
Other languages
French (fr)
Other versions
WO2004050896A2 (en
WO2004050896A9 (en
WO2004050896A3 (en
Inventor
John H Crowe
Fern Tablin
Willem Wolkers
Naomi J Walker
Sheri Looper
Nelly M Tsvetkova
Zsolt Torok
Original Assignee
Univ California
John H Crowe
Fern Tablin
Willem Wolkers
Naomi J Walker
Sheri Looper
Nelly M Tsvetkova
Zsolt Torok
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/635,353 external-priority patent/US20050033185A1/en
Priority claimed from US10/635,333 external-priority patent/US20040136974A1/en
Application filed by Univ California, John H Crowe, Fern Tablin, Willem Wolkers, Naomi J Walker, Sheri Looper, Nelly M Tsvetkova, Zsolt Torok filed Critical Univ California
Priority to AU2003302323A priority Critical patent/AU2003302323A1/en
Publication of WO2004050896A2 publication Critical patent/WO2004050896A2/en
Publication of WO2004050896A8 publication Critical patent/WO2004050896A8/en
Publication of WO2004050896A9 publication Critical patent/WO2004050896A9/en
Publication of WO2004050896A3 publication Critical patent/WO2004050896A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method for loading a preservative into a biological sample comprising providing a preservation solution having a preservative, water and protein, and loading a biological sample with the preservative solution to produce a preservative-loaded biological sample having the preservative solution generally including higher glass transition temperature than glass transition temperatures for a preservative solution having the preservative, water and no protein. A process for processing biological samples comprising suspending biological samples in a preservative solution at a concentration greater than about 108 platelets per ml. of preservative solution to produce preservation-loaded biological samples, freeze-drying the perservative-loaded biological samples, and recovering at least 70 % of the freeze-dried biological samples. A biological sample composition comprising a biological sample loaded with a preservative solution having a perservative, water, and protein, and generally further having higher glass transition temperatures than glass transition temperature for the biological sample loaded with the preservative, water, but no protein.
PCT/US2003/038133 2002-11-29 2003-11-28 A method and therapeutic platelets WO2004050896A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003302323A AU2003302323A1 (en) 2002-11-29 2003-11-28 A method and therapeutic platelets

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US43004002P 2002-11-29 2002-11-29
US60/430,040 2002-11-29
US10/635,353 US20050033185A1 (en) 2003-08-06 2003-08-06 Method for correcting vessel and background light intensities used in beer's law for light scattering in tissue
US10/635,333 US20040136974A1 (en) 2002-01-16 2003-08-06 Therapeutic platelets and methods
US10/635,333 2003-08-06
US10/635,353 2003-10-06

Publications (4)

Publication Number Publication Date
WO2004050896A2 WO2004050896A2 (en) 2004-06-17
WO2004050896A8 true WO2004050896A8 (en) 2004-08-05
WO2004050896A9 WO2004050896A9 (en) 2004-11-25
WO2004050896A3 WO2004050896A3 (en) 2006-12-21

Family

ID=33458679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/038133 WO2004050896A2 (en) 2002-11-29 2003-11-28 A method and therapeutic platelets

Country Status (2)

Country Link
AU (1) AU2003302323A1 (en)
WO (1) WO2004050896A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006020773A2 (en) 2004-08-12 2006-02-23 Adlyfe, Inc. Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
US7811558B2 (en) 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
US8097403B2 (en) 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
US11767511B2 (en) 2018-11-30 2023-09-26 Cellphire, Inc. Platelets as delivery agents
CA3121484A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets loaded with anti-cancer agents
AU2020267368B2 (en) 2019-05-03 2023-05-04 Cellphire, Inc. Materials and methods for producing blood products
AU2020334903B2 (en) 2019-08-16 2023-12-21 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
WO2021158646A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Treatment of von willebrand disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
GB9916790D0 (en) * 1999-07-16 1999-09-22 Health Lab Service Board Storage of microorganisms,cells and tissue

Also Published As

Publication number Publication date
WO2004050896A2 (en) 2004-06-17
AU2003302323A1 (en) 2004-06-23
AU2003302323A8 (en) 2004-06-23
WO2004050896A9 (en) 2004-11-25
WO2004050896A3 (en) 2006-12-21

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