WO2004050047A1 - Substance for the treatment of disorders of the hair root and diseases of the hair - Google Patents

Substance for the treatment of disorders of the hair root and diseases of the hair Download PDF

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Publication number
WO2004050047A1
WO2004050047A1 PCT/EP2002/013441 EP0213441W WO2004050047A1 WO 2004050047 A1 WO2004050047 A1 WO 2004050047A1 EP 0213441 W EP0213441 W EP 0213441W WO 2004050047 A1 WO2004050047 A1 WO 2004050047A1
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WO
WIPO (PCT)
Prior art keywords
angelica
hair
grams
agent
benzoic acid
Prior art date
Application number
PCT/EP2002/013441
Other languages
German (de)
French (fr)
Inventor
Yong-Ae Chon-Prinz
Original Assignee
Yong-Ae Chon-Prinz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yong-Ae Chon-Prinz filed Critical Yong-Ae Chon-Prinz
Priority to PCT/EP2002/013441 priority Critical patent/WO2004050047A1/en
Priority to AU2002352176A priority patent/AU2002352176A1/en
Publication of WO2004050047A1 publication Critical patent/WO2004050047A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]

Definitions

  • Alopecia diffuse hair loss and the circumscribed hair loss.
  • scalp disease also occurs with hair loss, which among other things also results in dandruff formation.
  • Hair loss is a disease that exists in both men and women.
  • the present invention relates to an agent for the treatment of hair root disorders and hair diseases, with the aim of preventing and treating hair loss.
  • Such agents are mainly rubbed into the scalp, so that the hair roots are better nourished and also better supplied with blood, with the result that hair growth is stimulated in places of the missing or decreasing hair on the head.
  • the standard requirement for this is, of course, that the hair roots are still present.
  • the object of the invention is therefore to provide a means for treating hair root disorders and hair diseases, which regenerates the scalp and stimulates hair growth and thus avoids the disadvantages of the prior art.
  • the herbs Angelica and Astragali Radix (tragacanth root) specified in the patent claim are brought to a boil for 1-8 hours with the addition of water at a temperature of 90-200 ° C. and then strained.
  • the resulting extract is preferably with diethanolamine (CH H NO 2 ) or optionally with a combination of triethanolamine (C 6 Hi5NO 3 ) and dioctyl sodium sulfosuccinate (C 20 H 37 NaO 7 S) and with benzoic acid (C 7 H 6 O 2 ) , which is dissolved in ethyl alcohol (C 2 H 6 O) diluted with the addition of distilled water.
  • the solution is then fermented in an ultrasound fermentation machine at about 15 kHz for 12 to 24 hours, so that the result reaches a pH between 7.5 and 9.0.
  • angelica root To produce the herbal extract, the following types of angelica root can also be used:

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Disclosed is a substance for the treatment of disorders of the hair root and diseases of the hair. Said substance is rubbed onto the scalp, supplying the hair roots with nutrients consisting of a herbal extract made of Angelica and astragali radix, resulting in the hair roots being regenerated and hair growth being stimulated.

Description

Mittel zur Behandlung von Haarwurzelstörungen und HaarerkrankungenAgents for the treatment of hair root disorders and hair diseases
Mittel zur Behandlung von Haarausfall und Haarerkrankungen werden schon seit Längerem erforscht und entwickelt.Agents for the treatment of hair loss and hair diseases have been researched and developed for a long time.
Haarausfall kommt in verschiedenen Formen vor.Hair loss occurs in different forms.
Die bekanntesten Formen sind der Anlagebedingter Haarausfall - "AndrohgenetischeThe most well-known forms are the hair loss caused by the plant - "androh genetic
Alopezie", Diffuser Haarausfall und der Umschriebener Haarausfall.Alopecia ", diffuse hair loss and the circumscribed hair loss.
Oft treten mit dem Haarausfall auch eine Erkrankung der Kopfhaut auf, was u.a. auch Schuppenbildung zur folge hat.Often, scalp disease also occurs with hair loss, which among other things also results in dandruff formation.
Haarausfall ist eine Krankheit, die sowohl bei Männern als auch bei Frauen besteht.Hair loss is a disease that exists in both men and women.
Die vorliegende Erfindung betrifft ein Mittel zur Behandlung von Haarwurzelstörungen und Haarerkrankungen, mit dem Ziel der Vorbeugung und Behandlung von Haarausfall. Solche Mittel werden vorwiegend in die Kopfhaut eingerieben, so dass die Haarwurzeln besser ernährt und auch besser durchblutet werden, was die Folge hat, dass an Stellen der fehlenden bzw. nachlassenden Kopfbehaarung das Haarwachstum angeregt wird. Norraussetzung hierfür ist selbstverständlich, dass die Haarwurzeln noch vorhanden sind.The present invention relates to an agent for the treatment of hair root disorders and hair diseases, with the aim of preventing and treating hair loss. Such agents are mainly rubbed into the scalp, so that the hair roots are better nourished and also better supplied with blood, with the result that hair growth is stimulated in places of the missing or decreasing hair on the head. The standard requirement for this is, of course, that the hair roots are still present.
Die bekannten Mittel zur Behandlung von Haarwurzelstörungen und Haarerkrankungen zeigen aber selten eine befriedigende Wirkung.The known agents for the treatment of hair root disorders and hair diseases rarely show a satisfactory effect.
Aufgabe der Erfindung ist es daher ein Mittel zur Behandlung von Haarwurzelstörungen und Haarerkrankungen bereitzustellen, was die Kopfhaut regeneriert und den Haarwuchs stimuliert und somit die Nachteile des bisherigen Stands der Technik vermeidet.The object of the invention is therefore to provide a means for treating hair root disorders and hair diseases, which regenerates the scalp and stimulates hair growth and thus avoids the disadvantages of the prior art.
Dies wird durch die im Patentanspruch angegebenen Substanzenzusammensetzung und die Herstellungsmethode erreicht.This is achieved by the substance composition and the production method specified in the claim.
Zur Herstellung des Mittels zur äußerlichen Behandlung von Haarerkrankungen und Haarwurzelstörungen werden die im Patentanspruch angegebenen Kräuter Angelica und Astragali Radix (Tragantwurzel) unter Zugabe von Wasser bei einer Temperatur von 90- 200°Celsius 1-8 Stunden zum Kochen gebracht und anschließend abgeseiht. Der entstandene Extrakt wird vorzugsweise mit Diethanolamin (C HHNO2 ) oder wahlweise mit einer Kombination aus Triethanolamin (C6Hi5NO3 ) und Dioctyl-Natriumsulfosuccinat (C20H37NaO7S) und mit Benzoesäure (C7H6O2), welche in Ethylalkohol (C2H6O) aufgelöst wird unter Zugabe von destilliertem Wasser verdünnt.To produce the agent for the external treatment of hair diseases and hair root disorders, the herbs Angelica and Astragali Radix (tragacanth root) specified in the patent claim are brought to a boil for 1-8 hours with the addition of water at a temperature of 90-200 ° C. and then strained. The resulting extract is preferably with diethanolamine (CH H NO 2 ) or optionally with a combination of triethanolamine (C 6 Hi5NO 3 ) and dioctyl sodium sulfosuccinate (C 20 H 37 NaO 7 S) and with benzoic acid (C 7 H 6 O 2 ) , which is dissolved in ethyl alcohol (C 2 H 6 O) diluted with the addition of distilled water.
Anschließend wird die Lösung in einer Ultraschall-Gärungsmaschine bei etwa 15 kHz 12 bis 24 Stunden gegoren, so dass das Ergebnis einen pH- Wert zwischen 7,5 bis 9.0 erreicht.The solution is then fermented in an ultrasound fermentation machine at about 15 kHz for 12 to 24 hours, so that the result reaches a pH between 7.5 and 9.0.
Zur Herstellung des Kräuterextrakts, können auch wahlweise auch folgende Arten der Angelicawurzel verwendet werden:To produce the herbal extract, the following types of angelica root can also be used:
Angelicae Gigantis Radix, Angelica Cutiloba Kitagawa, Angelica Archangelica, Angelica Sinensis, Angelica Uchiyamana, Ligusticum Acutilobum Krragawa und Angelica Gigas. Zur Herstellung von etwa 20 Litern des genannten Mittels benötigt man etwa 200 bis 1600 gram vom gewählten Angelicawurzel und 5 bis 100 gram Tragantwurzel in trockener Form. 30 bis 200 gram Diethanolamin, oder wahlweise auch eine Lösung aus Triethanolamin ( 30 bis 200 gram ) und Dioctyl-Natriumsulfosuccinat ( 20 bis 100 gram )und 5 bis 20 gram Benzoesäure aufgelöst in 800 ml Ethylalkohol.Angelicae Gigantis Radix, Angelica Cutiloba Kitagawa, Angelica Archangelica, Angelica Sinensis, Angelica Uchiyamana, Ligusticum Acutilobum Krragawa and Angelica Gigas. To produce about 20 liters of the agent mentioned, you need about 200 to 1600 grams of the chosen angelica root and 5 to 100 grams of tragacanth in dry form. 30 to 200 grams of diethanolamine, or alternatively a solution of triethanolamine (30 to 200 grams) and dioctyl sodium sulfosuccinate (20 to 100 grams) and 5 to 20 grams of benzoic acid dissolved in 800 ml of ethyl alcohol.
Das ganze Gemisch wird zum Schluss mit destilliertem Wasser bis zu einer Gesamtmenge von 20 l aufgefüllt. Finally, the whole mixture is filled up with distilled water up to a total of 20 l.

Claims

Patentanspruch ) Mittel zur Behandlung von Haarwurzelstörungen und Haarerkrankungen mit folgenden Inhaltsstoffen:Claim) Agent for the treatment of hair root disorders and hair diseases with the following ingredients:
Kräuterextrakt aus Angelica und Astragali Radix und / oder ihre Unterformen wie beispielsweise Angelicae Gigantis Radix, Angelica Cutiloba Kitagawa, Angelica Archangelica, Angelica Sinensis, Angelica Uchiyamana, Ligusticum Acutilobum Krragawa und Angelica GigasHerbal extract from Angelica and Astragali Radix and / or their sub-forms such as Angelicae Gigantis Radix, Angelica Cutiloba Kitagawa, Angelica Archangelica, Angelica Sinensis, Angelica Uchiyamana, Ligusticum Acutilobum Krragawa and Angelica Gigas
Eine Zusammensetzung aus Diethanolamin oder Triethanolamin und Dioctyl- Natriumsulfosuccinat.A composition of diethanolamine or triethanolamine and dioctyl sodium sulfosuccinate.
Eine Lösung aus Benzoesäure und Ethylalkohol. ) Herstellungsmethode der unter Anspruch 1 ) genannten Zusammensetzungen: hierbei wird die Zusammensetzung Kräuterextrakt, Diethanolamin oder eine Kombination aus Triethanolamin und Dioctyl-Natriumsulfosuccinat und die Lösung aus Benzoesäure und Ethylalkohol in einer Ultraschall-Gärungsmaschine für einen bestimmten Zeitraum gegoren. ) Die Herstellungsmethode gemäß 2 ), wobei die Gärungszeit zwischen 12 und 24 Stunden liegt. ) Die Herstellungsmethode gemäß 2 ), wobei die Gärungsmaschine bei einer Frequenz von etwa 10 kHz bis 20 kHz betrieben wird. ) Die Inhaltsstoffe gemäß 1 ), wobei die Menge der Kräuter Angelica zwischen 200 und 2000 gram in trockener Form bei einem Gesamtergebnis von 20 Litern des genannten Mittels beträgt. ) Die Inhaltsstoffe gemäß 1 ), wobei die Menge der Kräuter Astragali Radix zwischen 5 und 100 gram in trockener Form bei einem Gesamtergebnis von 20 Litern des genannten Mittels beträgt. ) Die Inhaltsstoffe gemäß 1 ), wobei die Lösung aus 5 bis 20 gram Benzoesäure und 800 Milliliter Ethanol besteht. ) Kräuterextrakt gemäß 1 ), wobei diese unter Zugabe von Wasser bei einer Temperatur von 90 bis 200 ° C in einem Zeitraum von 1 bis 8 Stunden hergestellt wird. ) Die Zusammensetzung gemäß 1 ), wobei diese einen pH- Wert von 7,5 bis 9,0 aufweist. A solution of benzoic acid and ethyl alcohol. ) Production method of the compositions mentioned in claim 1): the composition of herbal extract, diethanolamine or a combination of triethanolamine and dioctyl sodium sulfosuccinate and the solution of benzoic acid and ethyl alcohol are fermented in an ultrasound fermentation machine for a certain period of time. ) The production method according to 2), where the fermentation time is between 12 and 24 hours. ) The production method according to 2), wherein the fermentation machine is operated at a frequency of about 10 kHz to 20 kHz. ) The ingredients according to 1), whereby the amount of Angelica herbs is between 200 and 2000 grams in dry form with a total result of 20 liters of the said agent. ) The ingredients according to 1), whereby the amount of Astragali Radix herbs is between 5 and 100 grams in dry form with a total result of 20 liters of said agent. ) The ingredients according to 1), the solution consisting of 5 to 20 grams of benzoic acid and 800 milliliters of ethanol. ) Herbal extract according to 1), which is prepared with the addition of water at a temperature of 90 to 200 ° C in a period of 1 to 8 hours. ) The composition according to 1), which has a pH of 7.5 to 9.0.
PCT/EP2002/013441 2002-11-29 2002-11-29 Substance for the treatment of disorders of the hair root and diseases of the hair WO2004050047A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/EP2002/013441 WO2004050047A1 (en) 2002-11-29 2002-11-29 Substance for the treatment of disorders of the hair root and diseases of the hair
AU2002352176A AU2002352176A1 (en) 2002-11-29 2002-11-29 Substance for the treatment of disorders of the hair root and diseases of the hair

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PCT/EP2002/013441 WO2004050047A1 (en) 2002-11-29 2002-11-29 Substance for the treatment of disorders of the hair root and diseases of the hair

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1923048A1 (en) * 2006-11-10 2008-05-21 Henkel Kommanditgesellschaft auf Aktien Hair treatment to minimise hair damage

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01199904A (en) * 1987-10-03 1989-08-11 Shozaburo Fujii Hair regenerating agent
JPH01213215A (en) * 1988-02-19 1989-08-28 Shozaburo Fujii Hair tonic
CN1229665A (en) * 1999-01-07 1999-09-29 赵胜国 Hair growth agent
CN1293062A (en) * 1999-10-15 2001-05-02 程丁厚 Chinese medicine for treating alopecia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01199904A (en) * 1987-10-03 1989-08-11 Shozaburo Fujii Hair regenerating agent
JPH01213215A (en) * 1988-02-19 1989-08-28 Shozaburo Fujii Hair tonic
CN1229665A (en) * 1999-01-07 1999-09-29 赵胜国 Hair growth agent
CN1293062A (en) * 1999-10-15 2001-05-02 程丁厚 Chinese medicine for treating alopecia

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200003, Derwent World Patents Index; Class B04, AN 2000-024216, XP002246135 *
DATABASE WPI Section Ch Week 200145, Derwent World Patents Index; Class B04, AN 2001-418833, XP002246136 *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 501 (C - 652) 10 November 1989 (1989-11-10) *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 523 (C - 657) 21 November 1989 (1989-11-21) *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1923048A1 (en) * 2006-11-10 2008-05-21 Henkel Kommanditgesellschaft auf Aktien Hair treatment to minimise hair damage

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AU2002352176A1 (en) 2004-06-23

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