WO2004046725A3 - Substrates with biological membrane arrays and methods for their fabrication - Google Patents
Substrates with biological membrane arrays and methods for their fabrication Download PDFInfo
- Publication number
- WO2004046725A3 WO2004046725A3 PCT/US2003/035258 US0335258W WO2004046725A3 WO 2004046725 A3 WO2004046725 A3 WO 2004046725A3 US 0335258 W US0335258 W US 0335258W WO 2004046725 A3 WO2004046725 A3 WO 2004046725A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substrate
- biological
- membrane
- array
- specific binding
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 6
- 239000000758 substrate Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000003491 array Methods 0.000 title 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000000151 deposition Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000009871 nonspecific binding Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00385—Printing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00635—Introduction of reactive groups to the surface by reactive plasma treatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/0074—Biological products
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004553521A JP2006506642A (en) | 2002-11-20 | 2003-11-05 | Substrate with stable surface chemistry for biomembrane arrays and method of manufacturing the same |
EP03768689A EP1563303A2 (en) | 2002-11-20 | 2003-11-05 | Substrates for biological membrane arrays and methods for their fabrication |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/300,954 | 2002-11-20 | ||
US10/300,954 US20040096914A1 (en) | 2002-11-20 | 2002-11-20 | Substrates with stable surface chemistry for biological membrane arrays and methods for fabricating thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004046725A2 WO2004046725A2 (en) | 2004-06-03 |
WO2004046725A3 true WO2004046725A3 (en) | 2004-08-19 |
Family
ID=32297962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/035258 WO2004046725A2 (en) | 2002-11-20 | 2003-11-05 | Substrates with biological membrane arrays and methods for their fabrication |
Country Status (4)
Country | Link |
---|---|
US (2) | US20040096914A1 (en) |
EP (1) | EP1563303A2 (en) |
JP (1) | JP2006506642A (en) |
WO (1) | WO2004046725A2 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
US7297553B2 (en) * | 2002-05-28 | 2007-11-20 | Nanosphere, Inc. | Method for attachment of silylated molecules to glass surfaces |
WO2003006676A2 (en) * | 2001-07-13 | 2003-01-23 | Nanosphere, Inc. | Method for immobilizing molecules onto surfaces |
US7191901B2 (en) * | 2002-08-15 | 2007-03-20 | Corning Incorporated | Substrate container that does not degrade substrate surface |
JP4067463B2 (en) * | 2003-07-18 | 2008-03-26 | トヨタ自動車株式会社 | Control device for hybrid vehicle |
US7198768B2 (en) * | 2004-06-16 | 2007-04-03 | Corning Incorporated | Anti-degradation mechanisms for protecting aminated surfaces |
CA2475456A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to optimize analyte and antibody substrate binding by least energy adsorption |
CA2475240A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to measure dynamic internal calibration true dose response curves |
DK1800129T3 (en) * | 2004-09-23 | 2013-07-01 | Tripath Imaging Inc | Polycationic polymer coatings for immobilization of biological samples |
US20060110594A1 (en) * | 2004-11-24 | 2006-05-25 | Frutos Anthony G | Polymer-coated substrates for binding biomolecules and methods of making and using thereof |
NZ562794A (en) * | 2005-04-12 | 2010-07-30 | Sru Biosystems Inc | Proteolipid membrane & lipid membrane biosensor using a titanium surface |
US7781203B2 (en) * | 2005-12-29 | 2010-08-24 | Corning Incorporated | Supports for assaying analytes and methods of making and using thereof |
PT2121919E (en) | 2007-03-22 | 2012-05-17 | Heptares Therapeutics Ltd | Mutant g-protein coupled receptors and methods for selecting them |
DE102007016699A1 (en) * | 2007-04-04 | 2008-10-09 | Synentec Gmbh | Biochip for the fluorescence analysis of individual transporters |
BRPI0811305B1 (en) | 2007-05-09 | 2020-02-27 | Shell Internationale Research Maatschappij B.V. | EPOXIDATION CATALYST, A PROCESS FOR THE PREPARATION OF THE CATALYST AND A PROCESS FOR THE PRODUCTION OF AN OLEPHINE OXIDE, A 1,2-DIOL, A 1,2-DIOL ETHER, A 1,2-CARBONATE OR AN ALKANOLAMINE |
DE102007059166A1 (en) * | 2007-12-06 | 2009-06-10 | Synentec Gmbh | Device for measuring transport systems |
GB0724860D0 (en) * | 2007-12-20 | 2008-01-30 | Heptares Therapeutics Ltd | Screening |
WO2009137427A2 (en) * | 2008-05-07 | 2009-11-12 | Shell Oil Company | A process for the start-up of an epoxidation process, a process for the production of ethylene oxide, a 1,2-diol, a 1,2-diol ether, a 1,2-carbonate, or an alkanolamine |
GB201103256D0 (en) * | 2011-02-25 | 2011-04-13 | Ge Healthcare Uk Ltd | Solid support and method of recovering biological material therefrom |
US10174101B2 (en) | 2011-08-10 | 2019-01-08 | Heptares Therapeutics Limited | Stable proteins |
ES2676827T3 (en) | 2012-06-01 | 2018-07-25 | Heptares Therapeutics Limited | essays |
EP2803372A1 (en) | 2013-05-16 | 2014-11-19 | Universiteit Twente | Process for the preparation of an object supporting a lipid bilayer |
US20160334395A1 (en) * | 2014-01-21 | 2016-11-17 | Nanyang Technological University | Hydration layer/lipid bilayer structures |
WO2017038709A1 (en) | 2015-09-03 | 2017-03-09 | 浜松ホトニクス株式会社 | Surface-assisted laser desorption/ionization method, mass spectrometry method and mass spectrometry device |
CN106796198B (en) * | 2015-09-03 | 2020-06-30 | 浜松光子学株式会社 | Sample support and method for producing sample support |
EP4289356A3 (en) | 2015-09-09 | 2024-02-28 | Drawbridge Health, Inc. | Devices for sample collection, stabilization and preservation |
GB2576635B (en) | 2017-01-10 | 2020-08-05 | Drawbridge Health Inc | Devices, systems, and methods for sample collection |
JP2023063041A (en) * | 2021-10-22 | 2023-05-09 | 国立大学法人神戸大学 | Artificial biological membranes containing membrane proteins |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001070419A1 (en) * | 2000-03-23 | 2001-09-27 | Corning Incorporated | Method for fabricating supported bilayer-lipid membranes |
WO2001088182A2 (en) * | 2000-05-18 | 2001-11-22 | The Board Of Trustees Of The Leland Stanford Junior University | Lipid bilayer array methods and devices |
US20020019015A1 (en) * | 2000-08-10 | 2002-02-14 | Joydeep Lahiri | Arrays of biological membranes and methods and use thereof |
WO2002012546A2 (en) * | 2000-08-04 | 2002-02-14 | The Board Of Trustees Of The Leland Stanford Junior University | Biosensor arrays and methods |
US20020094544A1 (en) * | 2000-08-10 | 2002-07-18 | Ye Fang | Arrays of biological membranes and methods and use thereof |
EP1376124A2 (en) * | 2002-06-27 | 2004-01-02 | Corning Incorporated | Toxin detection and compound screening using biological membrane microarrays |
Family Cites Families (11)
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US4824529A (en) * | 1987-11-27 | 1989-04-25 | Allied-Signal Inc. | Lipid membrane-based device |
ES2102364T3 (en) * | 1989-01-27 | 1997-08-01 | Au Membrane & Biotech Res Inst | RECEIVING MEMBRANES AND CONTROL OF THE PASSAGE THROUGH THEM BY IONOPHORES. |
US5753516A (en) * | 1995-02-03 | 1998-05-19 | Heagy; Wyrta E. | Screening method for ligands of the EBI-1 receptor |
AT404838B (en) * | 1995-11-24 | 1999-03-25 | Immuno Ag | PRODUCTION OF PROTEINS FROM PRO-PROTEINS BY FUSION PROTEINS DERIVED FROM FURIN OR FURINANALOGS |
JP3822946B2 (en) * | 1996-05-30 | 2006-09-20 | 三洋電機株式会社 | Bilayer device |
US6406921B1 (en) * | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
US20020123071A1 (en) * | 2000-12-04 | 2002-09-05 | Knudsen Sanne Moller | Method of identifying compounds capable of acting as agonists or antagonists of G-protein coupled receptors |
SE0100875D0 (en) * | 2001-03-14 | 2001-03-14 | Biacore Ab | Method of preparing supported lipid film membranes and use thereof |
US7198768B2 (en) * | 2004-06-16 | 2007-04-03 | Corning Incorporated | Anti-degradation mechanisms for protecting aminated surfaces |
US7473533B2 (en) * | 2004-12-30 | 2009-01-06 | Corning Incorporated | Membrane arrays and methods of manufacture |
US7998414B2 (en) * | 2007-02-28 | 2011-08-16 | Corning Incorporated | System for high throughput GPCR functional assay |
-
2002
- 2002-11-20 US US10/300,954 patent/US20040096914A1/en not_active Abandoned
-
2003
- 2003-11-05 EP EP03768689A patent/EP1563303A2/en not_active Withdrawn
- 2003-11-05 JP JP2004553521A patent/JP2006506642A/en not_active Withdrawn
- 2003-11-05 WO PCT/US2003/035258 patent/WO2004046725A2/en not_active Application Discontinuation
-
2009
- 2009-05-08 US US12/437,893 patent/US20090215650A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2001070419A1 (en) * | 2000-03-23 | 2001-09-27 | Corning Incorporated | Method for fabricating supported bilayer-lipid membranes |
WO2001088182A2 (en) * | 2000-05-18 | 2001-11-22 | The Board Of Trustees Of The Leland Stanford Junior University | Lipid bilayer array methods and devices |
WO2002012546A2 (en) * | 2000-08-04 | 2002-02-14 | The Board Of Trustees Of The Leland Stanford Junior University | Biosensor arrays and methods |
US20020019015A1 (en) * | 2000-08-10 | 2002-02-14 | Joydeep Lahiri | Arrays of biological membranes and methods and use thereof |
US20020094544A1 (en) * | 2000-08-10 | 2002-07-18 | Ye Fang | Arrays of biological membranes and methods and use thereof |
WO2002092833A2 (en) * | 2001-05-14 | 2002-11-21 | Corning Incorporated | Arrays of biological membranes and methods and use thereof |
EP1376124A2 (en) * | 2002-06-27 | 2004-01-02 | Corning Incorporated | Toxin detection and compound screening using biological membrane microarrays |
Non-Patent Citations (1)
Title |
---|
FANG Y ET AL: "MEMBRANE PROTEIN IN MICROARRAYS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 124, no. 11, 26 February 2002 (2002-02-26), pages 2394 - 2395, XP001156134, ISSN: 0002-7863 * |
Also Published As
Publication number | Publication date |
---|---|
US20090215650A1 (en) | 2009-08-27 |
JP2006506642A (en) | 2006-02-23 |
US20040096914A1 (en) | 2004-05-20 |
WO2004046725A2 (en) | 2004-06-03 |
EP1563303A2 (en) | 2005-08-17 |
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