WO2004045410A1 - An apparatus and a method for urological measurements - Google Patents

An apparatus and a method for urological measurements Download PDF

Info

Publication number
WO2004045410A1
WO2004045410A1 PCT/DK2003/000782 DK0300782W WO2004045410A1 WO 2004045410 A1 WO2004045410 A1 WO 2004045410A1 DK 0300782 W DK0300782 W DK 0300782W WO 2004045410 A1 WO2004045410 A1 WO 2004045410A1
Authority
WO
WIPO (PCT)
Prior art keywords
control unit
measurements
central control
urological
data
Prior art date
Application number
PCT/DK2003/000782
Other languages
French (fr)
Inventor
Niels Kristian Kristiansen
Hans Harding
Original Assignee
Urodan Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Urodan Aps filed Critical Urodan Aps
Priority to AU2003280322A priority Critical patent/AU2003280322A1/en
Publication of WO2004045410A1 publication Critical patent/WO2004045410A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0858Detecting organic movements or changes, e.g. tumours, cysts, swellings involving measuring tissue layers, e.g. skin, interfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/202Assessing bladder functions, e.g. incontinence assessment
    • A61B5/204Determining bladder volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/202Assessing bladder functions, e.g. incontinence assessment
    • A61B5/205Determining bladder or urethral pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/207Sensing devices adapted to collect urine
    • A61B5/208Sensing devices adapted to collect urine adapted to determine urine quantity, e.g. flow, volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4472Wireless probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/42Details of probe positioning or probe attachment to the patient
    • A61B8/4209Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
    • A61B8/4227Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by straps, belts, cuffs or braces

Definitions

  • the invention relates to an apparatus for the performance of urological measurements with one or more measuring apparatuses.
  • the invention also relates to a method for the performance of urological measurements with one or more measuring apparatuses.
  • measuring equipment There are several types of measuring equipment which are incorporated in ordinary clinical practice, including equipment for measuring the bladder volume, equipment for measuring the bladder pressure, and equipment for measuring the urination rate.
  • the cables included in the measuring apparatus restrict the freedom of movement for the patients being measured, which in turn restrits the clinical examination options. Thus, it will frequently be very difficult to examine patients e.g. in a normal everyday or work situation, which might otherwise give important clinical information.
  • the absent synchronization between several different types of measuring equipment also means that it is very difficult in practice to make several different measurements at the same time.
  • the absent synchronization means inter alia that a common time reference is lacking, and consequently the individual data cannot be compared temporally.
  • an object of the invention is to improve the prior art apparatus and the prior art method for urological measurements.
  • the object of the invention is achieved by an apparatus of the type defined in the introductory portion of claim 1 , which is characterized in that the measurements are controlled wirelessly by a central control unit.
  • the wireless communication is carried out according to the Bluetooth standard.
  • the use of the Bluetooth standard ensures that the apparatuses communicating wirelessly with each other can do so with a minimized risk of unin- tentional interference with other irrelevant electronic equipment, while minimizing the hardware costs.
  • control unit is portable. This provides additional flexibility in a clinical measurement situation, as the person operating the central unit may move about freely in relation to the patient being measured.
  • control unit contains a hand-held computer.
  • This e.g. opens up the possibility of programming the control of the urological measurements such that these are optimized for the given patient and the given clinical situation.
  • the central unit may be programmed to process the recorded measurement results, so that the user may have essential clinical information during as well as immediately after the measurements.
  • the invention also relates to a method.
  • This method is characterized in that the measurements are controlled wirelessly from a central control unit.
  • Fig. 1 shows a typical measurement situation, where a central unit controls a bladder volume measurement and a urination measurement as well as communicates with an external main computer.
  • Fig. 2 shows a block diagram of the wireless coupling of a central control unit and four other units.
  • Fig. 3 shows a flowchart of the course of a typical measuring sequence for the recording of urine flow and volume.
  • Fig. 4 shows the relation between urine volume change over time and the flow rate which forms the basis for data processing.
  • the numeral 1 designates a central control unit in the form of a hand-held computer provided with a wireless Bluetooth interface for communication with other units.
  • the figure shows a patient 2 provided with a belt which accommodates an ultrasound based sensor for the recording of bladder volume.
  • the ultra- sound sensor is battery-powered and is provided with a Bluetooth interface such that the measuring equipment can communicate wirelessly with the central unit.
  • a urine volume meter 4 can record the urination of the patient and can also communicate with the central unit via Bluetooth.
  • the central unit 1 can temporally synchronize the other units and start as well as stop measurements according to the user's specific needs, whereby one or more examinations may be performed with optimum clinical information as a result.
  • data may optionally be transferred to a main computer 5, where demanding clinical algorithms can process the measured data in real time.
  • the central unit 1 may also be provided with algorithms for the processing of data with a view to presenting clinical valuable information to the user during and after the recording of measurement data.
  • the patient is not wired to external units. Therefore, the patient has unrestricted freedom of movement and may therefore be measured in situations which are not possible where cables are to transmit measurement data to other equipment.
  • Fig. 2 shows a block diagram where 1 is the central control unit which wirelessly controls a urine flow meter 2, a bladder volume monitor 3, a bladder pressure meter 7 and a PC with clinical data programs 5.
  • a process for the measurement of urine volume and urine flow rate may proceed.
  • the process is started via a wireless signal from the central control unit.
  • the volume of urine is determined by a bal- ance and the weight is converted into a volume value.
  • Differentiation of volume data provides the flow rate, and data may now be presented to the user who can include the information as part of the basis for the making of a diagnosis.
  • data may currently be sent to the central control unit where the data processing may be carried out and the results be presented to the user/clinician.
  • Data may also be processed in the measuring unit, from where the proc- essed data are then passed on to the central control unit.
  • the central control unit may transfer raw data or partially processed data to a main computer, in which the clinical calculations may then be performed, be presented to the clinician, and optionally be saved in an electronic patient record.
  • the central control unit may also send raw data as well as processed clinical information directly to an external computer, where data may be stored in an electronic patient record.
  • Fig. 4 shows a typical course of data collected from a patient's urination, where (a) shows how the urine volume changes over time, and where (b) shows the first derivative of (a), thereby producing the urine flow rate.
  • the algorithm forming the basis for the data processing may e.g. be programmed in the central control unit, which may then give the clinician the relevant information in real time.

Abstract

The invention relates to an apparatus and a method for urological measurements. The apparatus is based on a central control unit which wirelessly controls one or more measuring apparatuses, from which urinary tract relevant data are collected. The central control unit synchronizes the measurements and can pool data collections running in parallel, such that e.g. bladder volume and bladder pressure may be recorded at the same time and data be compared in real time. Since all units communicate wirelessly, the patient’s freedom of movement is unrestricted, which allows measurement and data collection in environments where the patient moves freely about. The wireless communication used is carried out according to the Bluetooth standard in a preferred embodiment. The method of the invention comprises control of one or more urological measuring processes and appliances with a central control unit which wirelessly communicates with the measuring equipment used.

Description

An apparatus and a method for urological measurements
The invention relates to an apparatus for the performance of urological measurements with one or more measuring apparatuses.
The invention also relates to a method for the performance of urological measurements with one or more measuring apparatuses.
It is known to perform urological measurements, which are e.g. used as part of the diagnosis of urinary tract diseases.
There are several types of measuring equipment which are incorporated in ordinary clinical practice, including equipment for measuring the bladder volume, equipment for measuring the bladder pressure, and equipment for measuring the urination rate.
It has been found, however, that this prior art involves some drawbacks, as the known apparatuses are separate units which make individual measurements without reference to another measuring apparatus, and frequently require electrical wiring to e.g. computer systems which are to process the measurement results.
The cables included in the measuring apparatus restrict the freedom of movement for the patients being measured, which in turn restrits the clinical examination options. Thus, it will frequently be very difficult to examine patients e.g. in a normal everyday or work situation, which might otherwise give important clinical information.
The absent synchronization between several different types of measuring equipment also means that it is very difficult in practice to make several different measurements at the same time. The absent synchronization means inter alia that a common time reference is lacking, and consequently the individual data cannot be compared temporally.
Accordingly, an object of the invention is to improve the prior art apparatus and the prior art method for urological measurements.
The object of the invention is achieved by an apparatus of the type defined in the introductory portion of claim 1 , which is characterized in that the measurements are controlled wirelessly by a central control unit.
Hereby, it is thus possible to avoid the cables which otherwise restrict the patient's freedom of movement, which, inter alia, allows urological measurements to be performed in situations where the patient moves freely about.
This might e.g. be in the normal private surroundings or at the patient's place of work or in other environments where it is considered essential to have an insight into the possible impact of the environment on the patient.
As stated in claim 2, it is moreover characteristic of the invention that the wireless communication is carried out according to the Bluetooth standard.
The use of the Bluetooth standard ensures that the apparatuses communicating wirelessly with each other can do so with a minimized risk of unin- tentional interference with other irrelevant electronic equipment, while minimizing the hardware costs.
It is stated in claim 3 that the invention is unique in that the control unit is portable. This provides additional flexibility in a clinical measurement situation, as the person operating the central unit may move about freely in relation to the patient being measured.
It is moreover stated in claim 4 that it is a special property of the central unit of the invention that the control unit contains a hand-held computer.
This e.g. opens up the possibility of programming the control of the urological measurements such that these are optimized for the given patient and the given clinical situation.
At the same time, the central unit may be programmed to process the recorded measurement results, so that the user may have essential clinical information during as well as immediately after the measurements.
Other expedient embodiments of the apparatus are defined in claims 5 and 6.
As mentioned, the invention also relates to a method.
This method is characterized in that the measurements are controlled wirelessly from a central control unit.
This makes it possible to perform urological measurements in new clinical situations which require unrestricted freedom of movement for the patient being measured.
The invention will now be explained more fully with reference to the drawings, in which: Fig. 1 shows a typical measurement situation, where a central unit controls a bladder volume measurement and a urination measurement as well as communicates with an external main computer.
Fig. 2 shows a block diagram of the wireless coupling of a central control unit and four other units.
Fig. 3 shows a flowchart of the course of a typical measuring sequence for the recording of urine flow and volume.
Fig. 4 shows the relation between urine volume change over time and the flow rate which forms the basis for data processing.
In fig. 1 , the numeral 1 designates a central control unit in the form of a hand-held computer provided with a wireless Bluetooth interface for communication with other units.
The figure shows a patient 2 provided with a belt which accommodates an ultrasound based sensor for the recording of bladder volume. The ultra- sound sensor is battery-powered and is provided with a Bluetooth interface such that the measuring equipment can communicate wirelessly with the central unit.
A urine volume meter 4 can record the urination of the patient and can also communicate with the central unit via Bluetooth.
5 designates a main computer, which can likewise communicate wirelessly with the central unit via a Bluetooth interface. Of course, the invention may also be worked with other wireless technologies than the Bluetooth standard, which thus does not restrict the scope of protection of the invention.
The central unit 1 can temporally synchronize the other units and start as well as stop measurements according to the user's specific needs, whereby one or more examinations may be performed with optimum clinical information as a result.
During and after the measurements, data may optionally be transferred to a main computer 5, where demanding clinical algorithms can process the measured data in real time.
The central unit 1 may also be provided with algorithms for the processing of data with a view to presenting clinical valuable information to the user during and after the recording of measurement data.
As will be seen from fig. 1 , the patient is not wired to external units. Therefore, the patient has unrestricted freedom of movement and may therefore be measured in situations which are not possible where cables are to transmit measurement data to other equipment.
Fig. 2 shows a block diagram where 1 is the central control unit which wirelessly controls a urine flow meter 2, a bladder volume monitor 3, a bladder pressure meter 7 and a PC with clinical data programs 5.
It is shown in fig. 3 how a process for the measurement of urine volume and urine flow rate may proceed. The process is started via a wireless signal from the central control unit. The volume of urine is determined by a bal- ance and the weight is converted into a volume value. Differentiation of volume data provides the flow rate, and data may now be presented to the user who can include the information as part of the basis for the making of a diagnosis.
It is part of the invention that data may currently be sent to the central control unit where the data processing may be carried out and the results be presented to the user/clinician.
Data may also be processed in the measuring unit, from where the proc- essed data are then passed on to the central control unit.
Finally, the central control unit may transfer raw data or partially processed data to a main computer, in which the clinical calculations may then be performed, be presented to the clinician, and optionally be saved in an electronic patient record.
The central control unit may also send raw data as well as processed clinical information directly to an external computer, where data may be stored in an electronic patient record.
Fig. 4 shows a typical course of data collected from a patient's urination, where (a) shows how the urine volume changes over time, and where (b) shows the first derivative of (a), thereby producing the urine flow rate.
The algorithm forming the basis for the data processing, as shown in fig. 4, may e.g. be programmed in the central control unit, which may then give the clinician the relevant information in real time.
It is part of the present invention to derive optimum information from the measured values, including e.g. by differentiating the found values of urine flow rate, thereby producing the urine flow acceleration from which new clinically relevant information may be derived.

Claims

PATENT CLAIMS
1. An apparatus for the performance of urological measurements with one or more measuring apparatuses, ch a racte rized in that the meas- urements are controlled wirelessly by a central control unit.
2. An apparatus for the performance of urological measurements according to claim ^characterized in that the wireless communication is carried out according to the Bluetooth standard.
3. A central control unit according to claim 1 or 2, characterized in that the control unit is portable.
4. A central control unit according to claim 1,2 or 3, characterized in that the control unit contains a hand-held computer.
5. A central control unit according to one or more of the preceding claims, ch a racterized in that the control unit may temporally synchronize the measuring apparatuses which it controls.
6. A central control unit according to one or more of the preceding claims, characterized in that the control unit may collect, process and present data from wirelessly coupled measuring apparatuses.
7. A method for the performance of urological measurements with one or more measuring apparatuses, cha ra cterized in that the measurements are controlled wirelessly from a central control unit.
PCT/DK2003/000782 2002-11-19 2003-11-14 An apparatus and a method for urological measurements WO2004045410A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003280322A AU2003280322A1 (en) 2002-11-19 2003-11-14 An apparatus and a method for urological measurements

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DKPA200201783 2002-11-19
DKPA200201783 2002-11-19

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006051464A1 (en) * 2004-11-12 2006-05-18 Koninklijke Philips Electronics, N.V. Method for automatic association of medical devices to a patient and concurrent creation of a patient record
ES2312287A1 (en) * 2008-03-17 2009-02-16 Hospital Sant Joan De Deu Device for treatment of night enuresis. (Machine-translation by Google Translate, not legally binding)
WO2011003239A1 (en) * 2009-07-09 2011-01-13 中山大学 Non-invasive urinary bladder pressure testing apparatus and method thereof
CN103393430A (en) * 2013-08-08 2013-11-20 上海赛琅医药科技有限公司 Urodynamic analyzer
WO2016085341A1 (en) * 2014-11-27 2016-06-02 Umc Utrecht Holding B.V. Wearable ultrasound device for signalling changes in human or animal body
US11911160B2 (en) 2018-08-10 2024-02-27 C. R. Bard, Inc. Automated urine output measurement systems and methods thereof
US11931151B2 (en) 2020-12-22 2024-03-19 C. R. Bard, Inc. Automated urinary output measuring system
US11938277B2 (en) 2018-05-22 2024-03-26 C. R. Bard, Inc. Catheterization system and methods for use thereof
WO2024064677A1 (en) * 2022-09-21 2024-03-28 Hollister Incorporated Sensors for monitoring bladder pressure

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999062402A1 (en) * 1998-06-01 1999-12-09 Alcor Medical Instruments Inc. A device for monitoring bladder urine distention in patients, and a method thereof
US20020016719A1 (en) * 2000-06-19 2002-02-07 Nemeth Louis G. Methods and systems for providing medical data to a third party in accordance with configurable distribution parameters
JP2002186601A (en) * 2000-12-22 2002-07-02 Tanita Corp Urination measurement device
WO2002082984A1 (en) * 2001-04-17 2002-10-24 Micrel Medical Devices S.A. System for monitoring medical parameters

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999062402A1 (en) * 1998-06-01 1999-12-09 Alcor Medical Instruments Inc. A device for monitoring bladder urine distention in patients, and a method thereof
US20020016719A1 (en) * 2000-06-19 2002-02-07 Nemeth Louis G. Methods and systems for providing medical data to a third party in accordance with configurable distribution parameters
JP2002186601A (en) * 2000-12-22 2002-07-02 Tanita Corp Urination measurement device
WO2002082984A1 (en) * 2001-04-17 2002-10-24 Micrel Medical Devices S.A. System for monitoring medical parameters

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 2002, no. 11 6 November 2002 (2002-11-06) *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006051464A1 (en) * 2004-11-12 2006-05-18 Koninklijke Philips Electronics, N.V. Method for automatic association of medical devices to a patient and concurrent creation of a patient record
US8058986B2 (en) 2004-11-12 2011-11-15 Koninklijke Philips Electronics N.V. Method for automatic association devices to a patient and concurrent creation of a patient record
ES2312287A1 (en) * 2008-03-17 2009-02-16 Hospital Sant Joan De Deu Device for treatment of night enuresis. (Machine-translation by Google Translate, not legally binding)
WO2011003239A1 (en) * 2009-07-09 2011-01-13 中山大学 Non-invasive urinary bladder pressure testing apparatus and method thereof
CN103393430A (en) * 2013-08-08 2013-11-20 上海赛琅医药科技有限公司 Urodynamic analyzer
WO2016085341A1 (en) * 2014-11-27 2016-06-02 Umc Utrecht Holding B.V. Wearable ultrasound device for signalling changes in human or animal body
NL2013884B1 (en) * 2014-11-27 2016-10-11 Umc Utrecht Holding Bv Wearable ultrasound device for signalling changes in human or animal body.
US11064924B2 (en) 2014-11-27 2021-07-20 Novioscan B.V. Wearable ultrasound device for signalling changes in a human or animal body
US11938277B2 (en) 2018-05-22 2024-03-26 C. R. Bard, Inc. Catheterization system and methods for use thereof
US11911160B2 (en) 2018-08-10 2024-02-27 C. R. Bard, Inc. Automated urine output measurement systems and methods thereof
US11931151B2 (en) 2020-12-22 2024-03-19 C. R. Bard, Inc. Automated urinary output measuring system
WO2024064677A1 (en) * 2022-09-21 2024-03-28 Hollister Incorporated Sensors for monitoring bladder pressure

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