WO2004043333A3 - Composite ameliorant la formation osseuse - Google Patents

Composite ameliorant la formation osseuse Download PDF

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Publication number
WO2004043333A3
WO2004043333A3 PCT/IL2003/000962 IL0300962W WO2004043333A3 WO 2004043333 A3 WO2004043333 A3 WO 2004043333A3 IL 0300962 W IL0300962 W IL 0300962W WO 2004043333 A3 WO2004043333 A3 WO 2004043333A3
Authority
WO
WIPO (PCT)
Prior art keywords
composite
enhancing composite
bone
bone enhancing
supplementary bioactive
Prior art date
Application number
PCT/IL2003/000962
Other languages
English (en)
Other versions
WO2004043333A2 (fr
Inventor
Avner Yayon
Original Assignee
Prochon Biotech Ltd
Avner Yayon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL153699A external-priority patent/IL153699A/en
Application filed by Prochon Biotech Ltd, Avner Yayon filed Critical Prochon Biotech Ltd
Priority to US10/534,794 priority Critical patent/US7887831B2/en
Priority to AU2003283785A priority patent/AU2003283785A1/en
Publication of WO2004043333A2 publication Critical patent/WO2004043333A2/fr
Publication of WO2004043333A3 publication Critical patent/WO2004043333A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention se rapporte à une matière composite améliorant la formation osseuse et comportant de l'apatite synthétique et au moins un agent bioactif supplémentaire sélectionné parmi un polymère biocompatible et un agent anti-résorption ajouté ab initio, ainsi qu'à des procédés de préparation dudit composite et à des utilisations de celui-ci. Les propriétés physiques et biologiques de ce composite sont régulées au moyen de l'addition d'agents bioactifs supplémentaires spécifiques ainsi que d'agents thérapeutiques facultatifs. Ce composite peut être utilisé sous la forme d'une poudre, d'une pâte ou d'un implant.
PCT/IL2003/000962 2002-11-14 2003-11-13 Composite ameliorant la formation osseuse WO2004043333A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/534,794 US7887831B2 (en) 2002-12-26 2003-11-13 Bone enhancing composite
AU2003283785A AU2003283785A1 (en) 2002-11-14 2003-11-13 Bone enhancing composite

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ILPCT/IL02/00913 2002-11-14
IL0200913 2002-11-14
IL153699A IL153699A (en) 2002-12-26 2002-12-26 The composition for transplantation basically
IL153699 2002-12-26

Publications (2)

Publication Number Publication Date
WO2004043333A2 WO2004043333A2 (fr) 2004-05-27
WO2004043333A3 true WO2004043333A3 (fr) 2004-07-15

Family

ID=32314004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2003/000962 WO2004043333A2 (fr) 2002-11-14 2003-11-13 Composite ameliorant la formation osseuse

Country Status (2)

Country Link
AU (1) AU2003283785A1 (fr)
WO (1) WO2004043333A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7504374B2 (en) * 2000-10-24 2009-03-17 Warsaw Orthopedic, Inc. Method for inducing deposition and maturation of bone comprising a co-therapeutic regimen of LMP-1 and BMP-2
US8298528B2 (en) 2006-04-17 2012-10-30 Hepacore Ltd. Methods for bone regeneration using endothelial progenitor cell preparations
WO2008005509A2 (fr) * 2006-07-06 2008-01-10 Massachusetts Institute Of Technology Procédés et compositions destinés à modifier des surfaces biologiques
WO2014020446A2 (fr) * 2012-08-01 2014-02-06 Sandvik Intellectual Property Ab Procédé de dépôt d'hydroxyapatite faisant appel à une technologie à micro-ondes
CN115232304B (zh) * 2022-07-26 2023-05-26 四川大学 含双膦酸聚氨基酸共聚物、抗骨肿瘤骨材料及其制备

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770229A (en) * 1994-05-13 1998-06-23 Kuraray Co., Ltd. Medical polymer gel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770229A (en) * 1994-05-13 1998-06-23 Kuraray Co., Ltd. Medical polymer gel

Also Published As

Publication number Publication date
WO2004043333A2 (fr) 2004-05-27
AU2003283785A8 (en) 2004-06-03
AU2003283785A1 (en) 2004-06-03

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