WO2004041115A3 - Novel human elastases and stress urinary incontinence - Google Patents

Novel human elastases and stress urinary incontinence Download PDF

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Publication number
WO2004041115A3
WO2004041115A3 PCT/US2003/018696 US0318696W WO2004041115A3 WO 2004041115 A3 WO2004041115 A3 WO 2004041115A3 US 0318696 W US0318696 W US 0318696W WO 2004041115 A3 WO2004041115 A3 WO 2004041115A3
Authority
WO
WIPO (PCT)
Prior art keywords
urinary incontinence
stress urinary
novel human
elastases
human elastases
Prior art date
Application number
PCT/US2003/018696
Other languages
French (fr)
Other versions
WO2004041115A2 (en
Inventor
Leslie Kushner
Mahesh Mathrubutham
Srinivasa K Rao
Original Assignee
Long Island Jewish Res Inst
Leslie Kushner
Mahesh Mathrubutham
Srinivasa K Rao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Long Island Jewish Res Inst, Leslie Kushner, Mahesh Mathrubutham, Srinivasa K Rao filed Critical Long Island Jewish Res Inst
Priority to AU2003299526A priority Critical patent/AU2003299526A1/en
Publication of WO2004041115A2 publication Critical patent/WO2004041115A2/en
Publication of WO2004041115A3 publication Critical patent/WO2004041115A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/966—Elastase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Novel elastases are provided that are associated with stress urinary incontinence. Also provided are methods for determining whether a woman has stress urinary incontinence, and methods for treating or preventing stress urinary incontinence.
PCT/US2003/018696 2002-06-14 2003-06-12 Novel human elastases and stress urinary incontinence WO2004041115A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003299526A AU2003299526A1 (en) 2002-06-14 2003-06-12 Novel human elastases and stress urinary incontinence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38909402P 2002-06-14 2002-06-14
US60/389,094 2002-06-14

Publications (2)

Publication Number Publication Date
WO2004041115A2 WO2004041115A2 (en) 2004-05-21
WO2004041115A3 true WO2004041115A3 (en) 2007-10-04

Family

ID=32312424

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/018696 WO2004041115A2 (en) 2002-06-14 2003-06-12 Novel human elastases and stress urinary incontinence

Country Status (2)

Country Link
AU (1) AU2003299526A1 (en)
WO (1) WO2004041115A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834350B2 (en) 2006-06-16 2014-09-16 Ams Research Corporation Surgical implants, tools, and methods for treating pelvic conditions
US9283064B2 (en) 2005-07-26 2016-03-15 Ams Research Corporation Methods and systems for treatment of prolapse

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL163453A0 (en) * 2004-08-10 2009-02-11 Yeda Res & Dev Enzyme inhibitor in leukemia
US7740576B2 (en) 2005-04-05 2010-06-22 Ams Research Corporation Articles, devices, and methods for pelvic surgery
WO2007137226A2 (en) 2006-05-19 2007-11-29 Ams Research Corporation Method and articles for treatment of stress urinary incontinence

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEN ET AL., NEUROLOGY AND URODYNAMICS, vol. 26, no. 2, 2007, pages 274 - 279 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283064B2 (en) 2005-07-26 2016-03-15 Ams Research Corporation Methods and systems for treatment of prolapse
US8834350B2 (en) 2006-06-16 2014-09-16 Ams Research Corporation Surgical implants, tools, and methods for treating pelvic conditions

Also Published As

Publication number Publication date
AU2003299526A8 (en) 2004-06-07
WO2004041115A2 (en) 2004-05-21
AU2003299526A1 (en) 2004-06-07

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