WO2004037856A3 - Facteur de virulence du var o du plasmodium falciparum - Google Patents
Facteur de virulence du var o du plasmodium falciparum Download PDFInfo
- Publication number
- WO2004037856A3 WO2004037856A3 PCT/EP2003/013341 EP0313341W WO2004037856A3 WO 2004037856 A3 WO2004037856 A3 WO 2004037856A3 EP 0313341 W EP0313341 W EP 0313341W WO 2004037856 A3 WO2004037856 A3 WO 2004037856A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- plasmodium falciparum
- var
- foregoing
- virulence factor
- factor var
- Prior art date
Links
- 241000223960 Plasmodium falciparum Species 0.000 title abstract 2
- 230000007923 virulence factor Effects 0.000 title 1
- 239000000304 virulence factor Substances 0.000 title 1
- 101150045515 O gene Proteins 0.000 abstract 1
- 230000000621 autoagglutination Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 abstract 1
- 201000004792 malaria Diseases 0.000 abstract 1
- 230000007193 modulation by symbiont of host erythrocyte aggregation Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000008506 pathogenesis Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003292133A AU2003292133A1 (en) | 2002-10-25 | 2003-10-24 | Plasmodium falciparum virulence factor var o |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002409897A CA2409897A1 (fr) | 2002-10-25 | 2002-10-25 | Facteur de virulence var o du plasmodium falciparum |
CA2,409,897 | 2002-10-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004037856A2 WO2004037856A2 (fr) | 2004-05-06 |
WO2004037856A3 true WO2004037856A3 (fr) | 2004-07-29 |
Family
ID=32111429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/013341 WO2004037856A2 (fr) | 2002-10-25 | 2003-10-24 | Facteur de virulence du var o du plasmodium falciparum |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2003292133A1 (fr) |
CA (1) | CA2409897A1 (fr) |
WO (1) | WO2004037856A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102781958B (zh) | 2009-12-05 | 2017-07-11 | 马尔瓦有限责任公司 | 基于顶复虫Ferlin、Ferlin样蛋白和其它含有C2结构域的蛋白的疟疾疫苗 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996033736A1 (fr) * | 1995-04-27 | 1996-10-31 | Affymax Technologies N.V. | Peptides du paludisme et vaccins associes |
-
2002
- 2002-10-25 CA CA002409897A patent/CA2409897A1/fr not_active Abandoned
-
2003
- 2003-10-24 AU AU2003292133A patent/AU2003292133A1/en not_active Abandoned
- 2003-10-24 WO PCT/EP2003/013341 patent/WO2004037856A2/fr not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996033736A1 (fr) * | 1995-04-27 | 1996-10-31 | Affymax Technologies N.V. | Peptides du paludisme et vaccins associes |
Non-Patent Citations (12)
Title |
---|
BARUCH DROR I ET AL: "Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 99, no. 6, 19 March 2002 (2002-03-19), March 19, 2002, pages 3860 - 3865, XP002279798, ISSN: 0027-8424 * |
CHEN Q ET AL: "IDENTIFICATION OF PLASMODIUM FALCIPARUM ERYTHROCYTE MEMBRANE PROTEIN 1 (PFEMP1) AS THE ROSETTING LIGAND OF THE MALARIA PARASITE P.FALCIPARUM", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 187, no. 1, 5 January 1998 (1998-01-05), pages 15 - 23, XP000918017, ISSN: 0022-1007 * |
DATABASE EMBL [online] ebi; 12 September 2002 (2002-09-12), TANG K. ET AL.,: "EST from plasmodium falciparum", XP002279719, Database accession no. BU497511 * |
DATABASE EMBL [online] EBI; 2 October 2002 (2002-10-02), SEEGER K. ET AL.,: "Plasmodium falciparum chromosome 8", XP002279717, Database accession no. AL844507 * |
DATABASE EMBL [online] ebi; 6 June 1997 (1997-06-06), ROWE J.A. ET AL.,: "Plasmodium falciparum R29R+var1 gene, exon 1", XP002279784, Database accession no. Y13402 * |
DATABASE EMBL [online] ebi; FRIED M ET AL.,: "plasmodium falciparum isolate PLC12a erythrocyte membrane protein 1 (var)", XP002279718, Database accession no. AF465502 * |
DATABASE EMBL [online] ebi; SMITH J.D. ET AL.,: "plasmodium falciparum (clone R29) var mRNA fragment", XP002279720, Database accession no. L42247 * |
LE SCANF CECILE ET AL: "Novel target antigens of the variant-specific immune response to Plasmodium falciparum identified by differential screening of an expression library", INFECTION AND IMMUNITY, vol. 67, no. 1, January 1999 (1999-01-01), pages 64 - 73, XP002279712, ISSN: 0019-9567 * |
LE SCANF CECILE ET AL: "Plasmodium falciparum: Altered expression of erythrocyte membrane-associated antigens during antigenic variation", EXPERIMENTAL PARASITOLOGY, vol. 85, no. 2, 1997, pages 135 - 148, XP002279713, ISSN: 0014-4894 * |
ROWE J ALEXANDRA ET AL: "P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor", NATURE (LONDON), vol. 388, no. 6639, Y13402, 1997, pages 292 - 295, XP002279714, ISSN: 0028-0836 * |
SMITH JOSEPH D ET AL: "Classification of adhesive domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 family", MOLECULAR AND BIOCHEMICAL PARASITOLOGY, vol. 110, no. 2, October 2000 (2000-10-01), pages 293 - 310, XP002279716, ISSN: 0166-6851 * |
SMITH JOSEPH D ET AL: "Decoding the language of var genes and Plasmodium falciparum sequestration", TRENDS IN PARASITOLOGY, vol. 17, no. 11, November 2001 (2001-11-01), pages 538 - 545, XP002279715, ISSN: 1471-4922 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003292133A8 (en) | 2004-05-13 |
AU2003292133A1 (en) | 2004-05-13 |
WO2004037856A2 (fr) | 2004-05-06 |
CA2409897A1 (fr) | 2004-04-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2001012659A3 (fr) | Sequence d'adn humain | |
EP2264151A3 (fr) | Constructions à fusion et utilisation associée pour produire des anticorps avec un récepteur FC liant l'affinité et fonction effectrice | |
CA2190473A1 (fr) | Papillomavirus recombine de type l1 | |
WO1998050554A3 (fr) | POLYNUCLEOTIDES ET POLYPEPTIDES D'$i(ENTEROCOCCUS FAECALIS) | |
WO1998031818A3 (fr) | Polypeptides semblables a tace ou a la matrilysime | |
EP2368907A3 (fr) | Anticorps anti-Abeta et leur utilisation | |
WO2002008277A3 (fr) | Acides nucleiques, vecteurs, cellules hotes, polypeptides et leurs utilisations | |
DE69840387D1 (de) | Nik proteine, nukleinsäure sowie verfahren | |
WO1998031806A3 (fr) | RECEPTEURS Fc ET POLYPEPTIDES | |
WO2004067709A8 (fr) | Identification de genes essentiels d'aspergillus fumigatus et methodes d'utilisation | |
WO1995025171A3 (fr) | Sequences d'adn pour metalloproteases matricielles, leur production et leur utilisation | |
WO2003052076A3 (fr) | Identification de genes essentiels de cryptococcus neoformans et methodes d'utilisation associees | |
CN104845981B (zh) | 田鼠巴贝虫Bm1524抗原及其应用 | |
WO2003016551A3 (fr) | Proteine de liaison a l'acide salicylique codant des acides nucleiques, proteine de liaison a l'acide salicylique 2 (sabp2) et methodes d'utilisation associees | |
WO2003078603A3 (fr) | Ensembles de genes forts pour classification de gliomes | |
WO2001046225A3 (fr) | Antigenes anti-chlamydia, fragments d'adn correspondants et leurs utilisations | |
WO2004037856A3 (fr) | Facteur de virulence du var o du plasmodium falciparum | |
WO2001040313A3 (fr) | Proteines immunoregulatrices felines, molecules d'acide nucleique et leurs utilisations | |
WO1996039511A3 (fr) | Recepteur du genre c5a a sept transmembranes | |
WO2002102316A3 (fr) | Histone-deacetylase et procedes d'utilisation correspondants | |
WO2001075114A3 (fr) | Antigenes de $i(chlamydia) et fragments d'adn correspondants, et leur utilisation | |
ATE417106T1 (de) | Chlamydia antigene und deren korrespondierende dna fragmente und verwendungen davon | |
WO2002033046A3 (fr) | Genes relatifs au transport de glucose | |
WO1992011367A3 (fr) | Recepteurs lipidiques de micro-organismes et adhesines correspondantes, sequences d'adn codant des adhesines et utilisation desdites adhesines | |
WO2002048361A3 (fr) | Nouvelles proteines secretees et leurs utilisations |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |