WO2004036212A3 - Procedes pour determiner la teneur en endotoxines de liquides - Google Patents

Procedes pour determiner la teneur en endotoxines de liquides Download PDF

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Publication number
WO2004036212A3
WO2004036212A3 PCT/EP2003/011028 EP0311028W WO2004036212A3 WO 2004036212 A3 WO2004036212 A3 WO 2004036212A3 EP 0311028 W EP0311028 W EP 0311028W WO 2004036212 A3 WO2004036212 A3 WO 2004036212A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquids
determination
endotoxin content
endotoxin
content
Prior art date
Application number
PCT/EP2003/011028
Other languages
German (de)
English (en)
Other versions
WO2004036212A2 (fr
Inventor
Veit Otto
Michael Zimmermann
Andrea Schoen
Frank Hacket
Thomas Hartung
Original Assignee
Fresenius Hemocare Gmbh
Veit Otto
Michael Zimmermann
Andrea Schoen
Frank Hacket
Thomas Hartung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Hemocare Gmbh, Veit Otto, Michael Zimmermann, Andrea Schoen, Frank Hacket, Thomas Hartung filed Critical Fresenius Hemocare Gmbh
Priority to AU2003293601A priority Critical patent/AU2003293601A1/en
Publication of WO2004036212A2 publication Critical patent/WO2004036212A2/fr
Publication of WO2004036212A3 publication Critical patent/WO2004036212A3/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un procédé pour déterminer la teneur en endotoxines de liquides. Elle concerne également un contenant traversé par lesdits liquides, utilisé lors de la mise en oeuvre dudit procédé, ainsi que l'utilisation de certains éléments séparateurs lors de la mise en oeuvre d'un procédé servant à déterminer la teneur en endotoxines de liquides.
PCT/EP2003/011028 2002-10-11 2003-10-06 Procedes pour determiner la teneur en endotoxines de liquides WO2004036212A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003293601A AU2003293601A1 (en) 2002-10-11 2003-10-06 Method for the determination of the endotoxin content in liquids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10247430.3 2002-10-11
DE2002147430 DE10247430A1 (de) 2002-10-11 2002-10-11 Verfahren zur Bestimmung des Gehalts an Endotoxinen in Flüssigkeiten

Publications (2)

Publication Number Publication Date
WO2004036212A2 WO2004036212A2 (fr) 2004-04-29
WO2004036212A3 true WO2004036212A3 (fr) 2004-06-24

Family

ID=32049229

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/011028 WO2004036212A2 (fr) 2002-10-11 2003-10-06 Procedes pour determiner la teneur en endotoxines de liquides

Country Status (3)

Country Link
AU (1) AU2003293601A1 (fr)
DE (1) DE10247430A1 (fr)
WO (1) WO2004036212A2 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0444303A2 (fr) * 1990-03-01 1991-09-04 Becton, Dickinson and Company Détection de chlamydia en essai de passage à travers
EP0494085A1 (fr) * 1985-09-27 1992-07-08 The Regents Of The University Of California Anticorps monoclonaux, déterminants de bactéries gram-négatives qui lient
US5773306A (en) * 1996-05-24 1998-06-30 Trustees Of The University Of Pennsylvania Methods and kits for the detection of endotoxin
US6090292A (en) * 1997-02-12 2000-07-18 Fresenius Ag Device for purifying solutions containing proteins and use of the device
WO2000060354A1 (fr) * 1999-04-07 2000-10-12 Unilever Plc Immunoessai lipopolysaccharidique et dispositif d'analyse

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
US5594113A (en) * 1988-06-23 1997-01-14 Associates Of Cape Cod, Inc. Endotoxin binding and neutralizing protein and uses thereof
US5183740A (en) * 1990-02-23 1993-02-02 The United States Of America As Represented By The Secretary Of The Navy Flow immunosensor method and apparatus
DE4208732C2 (de) * 1992-03-18 1995-04-27 Abion Ohg Einwegreaktionsgefäß für die Festphasenimmunanalytik und Verfahren zur Messung von über Immunreaktionen bestimmbaren Komponenten
DE19516247A1 (de) * 1995-05-03 1996-11-07 Albrecht Prof Dr Wendel Pyrogen-Untersuchungsverfahren
DE19654266A1 (de) * 1996-12-23 1998-06-25 Albrecht Prof Dr Wendel Untersuchungsverfahren mit biologischem System

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0494085A1 (fr) * 1985-09-27 1992-07-08 The Regents Of The University Of California Anticorps monoclonaux, déterminants de bactéries gram-négatives qui lient
EP0444303A2 (fr) * 1990-03-01 1991-09-04 Becton, Dickinson and Company Détection de chlamydia en essai de passage à travers
US5773306A (en) * 1996-05-24 1998-06-30 Trustees Of The University Of Pennsylvania Methods and kits for the detection of endotoxin
US6090292A (en) * 1997-02-12 2000-07-18 Fresenius Ag Device for purifying solutions containing proteins and use of the device
WO2000060354A1 (fr) * 1999-04-07 2000-10-12 Unilever Plc Immunoessai lipopolysaccharidique et dispositif d'analyse

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
FENNRICH S ET AL: "DETECTION OF ENDOTOXINS AND OTHER PYROGENS USING HUMAN WHOLE BLOOD", DEVELOPMENTS IN BIOLOGICAL STANDARDIZATION, KARGER, BASEL, CH, vol. 101, 1999, pages 131 - 139, XP001106430, ISSN: 0301-5149 *
FENNRICH STEFAN ET AL: "Inflammatory response to pyrogens adsorbed to biomaterials determined by a novel whole blood In Vitro Pyrogen Test (IPT)", JOURNAL OF ENDOTOXIN RESEARCH, vol. 8, no. 3, 2002, 7th Biennial Conference of the International Endotoxin Society;D C, Washington, USA; July 18-21, 2002, pages 195, XP009029887, ISSN: 0968-0519 *
HARTUNG THOMAS ET AL: "Detection of pyrogens using human whole blood", IN VITRO TOXICOLOGY, vol. 9, no. 4, 1996, pages 353 - 359, XP009029690, ISSN: 0888-319X *
PETSCH D ET AL: "Proteinase K digestion of proteins improves detection of bacterial endotoxins by the Limulus amebocyte lysate assay: Application for endotoxin removal from cationic proteins", ANALYTICAL BIOCHEMISTRY, vol. 259, no. 1, 15 May 1998 (1998-05-15), pages 42 - 47, XP002277870, ISSN: 0003-2697 *
ZIMMERMANN MICHAEL ET AL: "Endotoxin adsorbent based on immobilized human serum albumin", CLINICAL CHEMISTRY AND LABORATORY MEDICINE, vol. 37, no. 3, March 1999 (1999-03-01), pages 373 - 379, XP009029688, ISSN: 1434-6621 *

Also Published As

Publication number Publication date
AU2003293601A8 (en) 2004-05-04
AU2003293601A1 (en) 2004-05-04
DE10247430A1 (de) 2004-04-29
WO2004036212A2 (fr) 2004-04-29

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