WO2004026242A3 - Substituted ketophosphonate inhibitors of tumor cell proliferation - Google Patents

Substituted ketophosphonate inhibitors of tumor cell proliferation Download PDF

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Publication number
WO2004026242A3
WO2004026242A3 PCT/US2003/029322 US0329322W WO2004026242A3 WO 2004026242 A3 WO2004026242 A3 WO 2004026242A3 US 0329322 W US0329322 W US 0329322W WO 2004026242 A3 WO2004026242 A3 WO 2004026242A3
Authority
WO
WIPO (PCT)
Prior art keywords
substituted
ketophosphonate
inhibitors
cell proliferation
tumor cell
Prior art date
Application number
PCT/US2003/029322
Other languages
French (fr)
Other versions
WO2004026242A2 (en
Inventor
Lan Mong Nguyen
Vinh Van Diep
Hieu Trung Phan
Eric Joseph Niesor
Daniele Masson
Yves Guyon-Gellin
Emanuele Buattini
Carlo Severi
Raymond Azoulay
Craig Leigh Bentzen
Original Assignee
Ilex Oncology Res Sarl
Lan Mong Nguyen
Vinh Van Diep
Hieu Trung Phan
Eric Joseph Niesor
Daniele Masson
Yves Guyon-Gellin
Emanuele Buattini
Carlo Severi
Raymond Azoulay
Craig Leigh Bentzen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ilex Oncology Res Sarl, Lan Mong Nguyen, Vinh Van Diep, Hieu Trung Phan, Eric Joseph Niesor, Daniele Masson, Yves Guyon-Gellin, Emanuele Buattini, Carlo Severi, Raymond Azoulay, Craig Leigh Bentzen filed Critical Ilex Oncology Res Sarl
Priority to AU2003272513A priority Critical patent/AU2003272513A1/en
Publication of WO2004026242A2 publication Critical patent/WO2004026242A2/en
Publication of WO2004026242A3 publication Critical patent/WO2004026242A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides for methods of treatment of cancer and the inhibition of the proliferation of tumor cells by substituted phosphonate compounds.
PCT/US2003/029322 2002-09-19 2003-09-18 Substituted ketophosphonate inhibitors of tumor cell proliferation WO2004026242A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003272513A AU2003272513A1 (en) 2002-09-19 2003-09-18 Substituted ketophosphonate inhibitors of tumor cell proliferation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41209002P 2002-09-19 2002-09-19
US60/412,090 2002-09-19

Publications (2)

Publication Number Publication Date
WO2004026242A2 WO2004026242A2 (en) 2004-04-01
WO2004026242A3 true WO2004026242A3 (en) 2004-07-15

Family

ID=32030801

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2003/029387 WO2004026243A2 (en) 2002-09-19 2003-09-18 Therapeutic uses of linear ketophosphonates
PCT/US2003/029322 WO2004026242A2 (en) 2002-09-19 2003-09-18 Substituted ketophosphonate inhibitors of tumor cell proliferation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2003/029387 WO2004026243A2 (en) 2002-09-19 2003-09-18 Therapeutic uses of linear ketophosphonates

Country Status (2)

Country Link
AU (2) AU2003272513A1 (en)
WO (2) WO2004026243A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
US6127350A (en) * 1995-07-28 2000-10-03 Symphar S.A. Use of phenol substituted diphosphonates as antineoplastic agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA941088B (en) * 1993-02-19 1995-09-27 Symphar Sa Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
US6127350A (en) * 1995-07-28 2000-10-03 Symphar S.A. Use of phenol substituted diphosphonates as antineoplastic agents

Also Published As

Publication number Publication date
AU2003272513A1 (en) 2004-04-08
AU2003272534A8 (en) 2004-04-08
WO2004026242A2 (en) 2004-04-01
WO2004026243A2 (en) 2004-04-01
WO2004026243A3 (en) 2004-06-03
AU2003272513A8 (en) 2004-04-08
AU2003272534A1 (en) 2004-04-08

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