WO2004024191A3 - Use of metallic particles to improve fluorescence imaging - Google Patents

Use of metallic particles to improve fluorescence imaging Download PDF

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Publication number
WO2004024191A3
WO2004024191A3 PCT/US2003/028074 US0328074W WO2004024191A3 WO 2004024191 A3 WO2004024191 A3 WO 2004024191A3 US 0328074 W US0328074 W US 0328074W WO 2004024191 A3 WO2004024191 A3 WO 2004024191A3
Authority
WO
WIPO (PCT)
Prior art keywords
metallic
fluorescence
exposing
irradiation
dye
Prior art date
Application number
PCT/US2003/028074
Other languages
French (fr)
Other versions
WO2004024191A2 (en
Inventor
Joseph R Lakowicz
Alex Parfenov
Ignacy Gryczynski
Johanna B Malicka
Chris D Geddes
Original Assignee
Univ Maryland
Joseph R Lakowicz
Alex Parfenov
Ignacy Gryczynski
Johanna B Malicka
Chris D Geddes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland, Joseph R Lakowicz, Alex Parfenov, Ignacy Gryczynski, Johanna B Malicka, Chris D Geddes filed Critical Univ Maryland
Priority to AU2003268537A priority Critical patent/AU2003268537A1/en
Publication of WO2004024191A2 publication Critical patent/WO2004024191A2/en
Publication of WO2004024191A3 publication Critical patent/WO2004024191A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
    • C03C17/006—Surface treatment of glass, not in the form of fibres or filaments, by coating with materials of composite character
    • C03C17/007—Surface treatment of glass, not in the form of fibres or filaments, by coating with materials of composite character containing a dispersed phase, e.g. particles, fibres or flakes, in a continuous phase
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C17/00—Surface treatment of glass, not in the form of fibres or filaments, by coating
    • C03C17/006—Surface treatment of glass, not in the form of fibres or filaments, by coating with materials of composite character
    • C03C17/008—Surface treatment of glass, not in the form of fibres or filaments, by coating with materials of composite character comprising a mixture of materials covered by two or more of the groups C03C17/02, C03C17/06, C03C17/22 and C03C17/28
    • C03C17/009—Mixtures of organic and inorganic materials, e.g. ormosils and ormocers
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C2217/00—Coatings on glass
    • C03C2217/40—Coatings comprising at least one inhomogeneous layer
    • C03C2217/43—Coatings comprising at least one inhomogeneous layer consisting of a dispersed phase in a continuous phase
    • C03C2217/46—Coatings comprising at least one inhomogeneous layer consisting of a dispersed phase in a continuous phase characterized by the dispersed phase
    • C03C2217/47—Coatings comprising at least one inhomogeneous layer consisting of a dispersed phase in a continuous phase characterized by the dispersed phase consisting of a specific material
    • C03C2217/475—Inorganic materials
    • C03C2217/479—Metals

Abstract

A material, metallic colloid or system for enhancing the fluorescence of dye upon exposing the material to irradiation. The material and metal colloid may contain indocyanine dye, albumin and a metallic particle such that the metallic particle provides enhancement of the fluorescence of the indocyanine dye upon exposing said material to irradiation. In the system, the indocyanine dye and the metallic particle are positioned at a distance sufficient to provide an enhancement of the fluorescence of the indocyanine dye upon exposing said system to irradiation. A method of imaging or assaying comprising administering the metallic colloid to a subject and irradiating said subject to detect the presence of indocyanine dye. And the use of metallic surfaces or particles deposited by laser illumination for enhancing the fluorescence a molecule upon exposing the material to irradiation.
PCT/US2003/028074 2002-09-10 2003-09-10 Use of metallic particles to improve fluorescence imaging WO2004024191A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003268537A AU2003268537A1 (en) 2002-09-10 2003-09-10 Use of metallic particles to improve fluorescence imaging

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40985002P 2002-09-10 2002-09-10
US40985102P 2002-09-10 2002-09-10
US60/409,850 2002-09-10
US60/409,851 2002-09-10

Publications (2)

Publication Number Publication Date
WO2004024191A2 WO2004024191A2 (en) 2004-03-25
WO2004024191A3 true WO2004024191A3 (en) 2008-01-10

Family

ID=31997871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/028074 WO2004024191A2 (en) 2002-09-10 2003-09-10 Use of metallic particles to improve fluorescence imaging

Country Status (2)

Country Link
AU (1) AU2003268537A1 (en)
WO (1) WO2004024191A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1583948B1 (en) 2002-11-26 2010-09-01 University of Maryland Biotechnology High-sensitivity assays for pathogen detection using metal-enhanced fluorescence
WO2006138698A2 (en) 2005-06-17 2006-12-28 University Of Maryland Biotechnology Institute Metal-enhanced fluorescence-based sensing methods
EP1671118B1 (en) 2003-09-17 2011-11-02 University of Maryland, Baltimore County Cyanide sensing compounds and uses thereof
CA2628056C (en) 2004-11-05 2013-05-28 University Of Maryland Biotechnology Institute Metal-enhanced fluorescence from plastic substrates
ES2565844T3 (en) 2004-11-19 2016-04-07 University Of Maryland Biotechnology Institute Accelerated microwave tests
CA2655079C (en) 2005-06-15 2013-12-10 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US8987004B2 (en) 2005-08-02 2015-03-24 University Of Maryland, Baltimore County Nanostructures for polarized imaging and receptor/ligan quantization: breaking the diffraction limit for imaging
US9500590B2 (en) 2006-02-13 2016-11-22 University Of Maryland, Baltimore County Assays for pathogen detection using microwaves for lysing and accelerating metal-enhanced fluorescence
US8980179B2 (en) 2006-05-17 2015-03-17 University Of Maryland, Baltimore County Angular-dependent metal-enhanced fluorescence
US9339485B2 (en) 2007-03-02 2016-05-17 University Of Maryland, Baltimore County Plasmonic engineering of singlet oxygen and/or superoxide generation
US9023372B2 (en) 2007-07-18 2015-05-05 University Of Maryland Metal-enhanced fluorescence nanoparticles
WO2009148634A2 (en) 2008-01-30 2009-12-10 University Of Maryland Biotechnology Institute Conversion of just-continuous metallic films to large particulate substrates for metal-enhanced fluorescence
US8679855B2 (en) 2008-03-03 2014-03-25 University Of Maryland, Baltimore County Voltage-gated metal-enhanced fluorescence, chemiluminescence or bioluminescence methods and systems
US8906701B2 (en) 2008-09-11 2014-12-09 University Of Maryland, Baltimore County Sonication-assisted metal-enhanced fluorescence (SAMEF)-based bioassays
WO2010033677A2 (en) 2008-09-17 2010-03-25 University Of Maryland Biotechnology Institute Plasmonic electricity
US10024850B2 (en) 2009-02-17 2018-07-17 University Of Maryland, Baltimore County Metal-enhanced bioluminescence: an approach for monitoring biological bioluminescent processes
US10024794B2 (en) 2009-02-23 2018-07-17 University Of Maryland, Baltimore County Directional surface plasmon coupled fluorescence and chemiluminescence from thin films of nickel, iron or palladium and uses thereof
US9810637B2 (en) 2009-12-14 2017-11-07 University Of Maryland, Baltimore County Plasmonic electricity
EP2513630B1 (en) 2009-12-17 2016-05-25 Chris Geddes A detection system using mixed-metal substrates for metal-enhanced fluorescence
EP2569394B1 (en) 2010-05-11 2015-11-04 University of Maryland, Baltimore County Method to enhance emissions of long-lived luminescent compounds
US8735175B2 (en) 2011-03-18 2014-05-27 Chris D. Geddes Multicolor microwave-accelerated metal-enhanced fluorescence (M-MAMEF)
EP2861264B1 (en) 2012-07-20 2019-02-06 Canon Kabushiki Kaisha Contrast agent for photoacoustic imaging
US9816990B2 (en) 2013-02-28 2017-11-14 University Of Maryland, Baltimore County Ultra-fast pathogen toxin detection assay based on microwave-accelerated metal-enhanced fluorescence
US10379050B2 (en) 2015-01-13 2019-08-13 University Of Maryland, Baltimore County Spectral shifts and modifications in metal-enhanced fluorescence, phosphorescence and alpha-fluorescence
US10294451B2 (en) 2015-04-22 2019-05-21 University Of Maryland, Baltimore County Flow and static lysing systems and methods for ultra-rapid isolation and fragmentation of biological materials by microwave irradiation
US11152294B2 (en) 2018-04-09 2021-10-19 Corning Incorporated Hermetic metallized via with improved reliability
WO2019240973A1 (en) * 2018-06-11 2019-12-19 Corning Incorporated Glass article having a metallic nanofilm and method for manufacturing the glass article
WO2020171940A1 (en) 2019-02-21 2020-08-27 Corning Incorporated Glass or glass ceramic articles with copper-metallized through holes and processes for making the same

Citations (1)

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US5182214A (en) * 1989-08-17 1993-01-26 Manfred Kessler Method for detection and determination of human serum albumin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5182214A (en) * 1989-08-17 1993-01-26 Manfred Kessler Method for detection and determination of human serum albumin

Non-Patent Citations (7)

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LAKOWICZ JOSEPH R ET AL: "Radiative decay engineering: 2. Effects of silver island films on fluorescence intensity, lifetimes, and resonance energy transfer", ANALYTICAL BIOCHEMISTRY, vol. 301, no. 2, 15 February 2002 (2002-02-15), pages 261 - 277, XP002267404, ISSN: 0003-2697 *
LAKOWICZ JOSEPH R: "Radiative decay engineering: Biophysical and biomedical applications", ANALYTICAL BIOCHEMISTRY, vol. 298, no. 1, 1 November 2001 (2001-11-01), pages 1 - 24, XP002267403, ISSN: 0003-2697 *
MALICKA JOANNA ET AL: "Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging.", JOURNAL OF BIOMEDICAL OPTICS. UNITED STATES JUL 2003, vol. 8, no. 3, July 2003 (2003-07-01), pages 472 - 478, XP002267402, ISSN: 1083-3668 *
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Also Published As

Publication number Publication date
AU2003268537A1 (en) 2004-04-30
WO2004024191A2 (en) 2004-03-25
AU2003268537A8 (en) 2008-03-06

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