WO2004019883A3 - Tick polypeptides as anticoagulants and vaccines - Google Patents

Tick polypeptides as anticoagulants and vaccines Download PDF

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Publication number
WO2004019883A3
WO2004019883A3 PCT/US2003/027071 US0327071W WO2004019883A3 WO 2004019883 A3 WO2004019883 A3 WO 2004019883A3 US 0327071 W US0327071 W US 0327071W WO 2004019883 A3 WO2004019883 A3 WO 2004019883A3
Authority
WO
WIPO (PCT)
Prior art keywords
tick
anticoagulants
polypeptides
vaccines
methods
Prior art date
Application number
PCT/US2003/027071
Other languages
French (fr)
Other versions
WO2004019883A2 (en
Inventor
Erol Fikrig
Fred Kantor
Sukanya Narasimhan
Michael Cappello
Raymond A Koski
Michel Ledizet
Original Assignee
Univ Yale
L2 Diagnostics Llc
Erol Fikrig
Fred Kantor
Sukanya Narasimhan
Michael Cappello
Raymond A Koski
Michel Ledizet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale, L2 Diagnostics Llc, Erol Fikrig, Fred Kantor, Sukanya Narasimhan, Michael Cappello, Raymond A Koski, Michel Ledizet filed Critical Univ Yale
Priority to CA002497148A priority Critical patent/CA2497148A1/en
Priority to AU2003268252A priority patent/AU2003268252A1/en
Publication of WO2004019883A2 publication Critical patent/WO2004019883A2/en
Publication of WO2004019883A3 publication Critical patent/WO2004019883A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Insects & Arthropods (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Polypeptides comprising tick polypeptides, portions and fragments thereof, including fusions, multimeric and chimeric proteins; nucleic acid molecules encoding them and antibodies directed against them. The various compositions are useful as anticoagulants, in compositions and methods for inducing tick immunity and preventing or reducing the transmission of tick-borne pathogens, and in diagnostic kits and methods.
PCT/US2003/027071 2002-08-30 2003-08-29 Tick polypeptides as anticoagulants and vaccines WO2004019883A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002497148A CA2497148A1 (en) 2002-08-30 2003-08-29 Tick polypeptides as anticoagulants and vaccines
AU2003268252A AU2003268252A1 (en) 2002-08-30 2003-08-29 Tick polypeptides as anticoagulants and vaccines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40821802P 2002-08-30 2002-08-30
US60/408,218 2002-08-30

Publications (2)

Publication Number Publication Date
WO2004019883A2 WO2004019883A2 (en) 2004-03-11
WO2004019883A3 true WO2004019883A3 (en) 2005-03-03

Family

ID=31978582

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/027071 WO2004019883A2 (en) 2002-08-30 2003-08-29 Tick polypeptides as anticoagulants and vaccines

Country Status (3)

Country Link
AU (1) AU2003268252A1 (en)
CA (1) CA2497148A1 (en)
WO (1) WO2004019883A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117045780B (en) * 2023-10-13 2023-12-15 成都大熊猫繁育研究基地 Application of brown yellow tick salivary gland protein in anti-tick vaccine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046499A1 (en) * 1999-12-03 2001-11-29 Kantor Fred S. Tick antigens and compositions and methods comprising them
US20010046976A1 (en) * 1998-08-13 2001-11-29 Reiner J. W. Class Antimicrobial histone h1 compositions, kits, and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046976A1 (en) * 1998-08-13 2001-11-29 Reiner J. W. Class Antimicrobial histone h1 compositions, kits, and methods of use thereof
US20010046499A1 (en) * 1999-12-03 2001-11-29 Kantor Fred S. Tick antigens and compositions and methods comprising them

Also Published As

Publication number Publication date
CA2497148A1 (en) 2004-03-11
WO2004019883A2 (en) 2004-03-11
AU2003268252A8 (en) 2004-03-19
AU2003268252A1 (en) 2004-03-19

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