WO2004018027A1 - Procede de regulation de l'etat physiologique d'un objet biologique a l'aide de melanges gazeux - Google Patents

Procede de regulation de l'etat physiologique d'un objet biologique a l'aide de melanges gazeux Download PDF

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Publication number
WO2004018027A1
WO2004018027A1 PCT/RU2002/000392 RU0200392W WO2004018027A1 WO 2004018027 A1 WO2004018027 A1 WO 2004018027A1 RU 0200392 W RU0200392 W RU 0200392W WO 2004018027 A1 WO2004018027 A1 WO 2004018027A1
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WO
WIPO (PCT)
Prior art keywords
mixture
gas
biological
installation
fact
Prior art date
Application number
PCT/RU2002/000392
Other languages
English (en)
Russian (ru)
Inventor
Aleksey Timofeyevich Logunov
Boris Nikolayevich Pavlov
Anatoliy Ivanovich Grigoriev
Original Assignee
Aleksey Timofeyevich Logunov
Boris Nikolayevich Pavlov
Anatoliy Ivanovich Grigoriev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aleksey Timofeyevich Logunov, Boris Nikolayevich Pavlov, Anatoliy Ivanovich Grigoriev filed Critical Aleksey Timofeyevich Logunov
Priority to AU2002349379A priority Critical patent/AU2002349379A1/en
Priority to PCT/RU2002/000392 priority patent/WO2004018027A1/fr
Publication of WO2004018027A1 publication Critical patent/WO2004018027A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0045Means for re-breathing exhaled gases, e.g. for hyperventilation treatment

Definitions

  • E ⁇ i e ⁇ e ⁇ y is ⁇ lzuyu ⁇ sya not ⁇ l ⁇ ⁇ i ⁇ vedenii
  • Oxygen and inert gases exhibit a physiological activity.
  • the physiological activity of the gases is manifested in the presence of gases in the presence of gaseous activity.
  • xenon and krupen in a mixture with acid are already at normal pressure, they cause a rupture, similar to the action of pain-relieving medications that are used in medicine.
  • helium for the treatment of bronchial obstructive diseases, such as bronchial asthma, etc. ( ⁇ agas ⁇ ⁇ . ⁇ ., General 1934, 80: 593; ⁇ Therapeuticikhihin G. ⁇ . ⁇ - ganism in the helium oxide environment. Leningrad, ⁇ auka, 1989, p. 157).
  • the task is also addressed by the fact that the installation and / or the disruption are carried out by changing the pressure and / or the composition of the gas mixture, the circulating biomass, and the off-gas.
  • the task is also solved by the fact that the installation and / or the destruction is carried out with the displacement of a smaller part of one of the ready-to-use mixture of gas vehicles.
  • the task is also solved by the fact that the installation and / or the disruption are carried out, in the case of, for example, the disruption is carried out in the course of the following.
  • the task is also solved by the fact that the installation and / or the destruction is carried out with a constant speed, for example, by introducing into the biological mixture of the gas.
  • the task is also solved by the fact that the installation and / or destruction is carried out with a variable speed, for example, by introducing into the biological mixture of the gas mixture.
  • the task is also solved by the fact that the installation and / or destruction is carried out by introducing into the biological mixture of gases that is / is not in use in the and / or hydrogen and / or six-phase sulfur and / or methane and / or nitrous oxide and / or mixtures thereof.
  • the oxygen content in the product is 12%.
  • the gas mixture can be introduced through the smoke mask and / or through the intubation tube, and / or through the helmet, and / or in the chamber of intensive therapy, and / or in the vicinity of the local flame.
  • Conventional gas mixtures are brought into normal or normal operation. There is no operation at a barometric pressure of 0.35-4 kgf / cm 2 and at a temperature of 18-100 celsius.
  • the operating environment can be supplied up to 4 seconds to 24 hours, while the cyclic mode of operation is ensured by a mixture of gases.
  • the biological product can also be prevented by this mixture during the course of 7 days.
  • an oxygen-containing gas mixture inhalants and / or medical devices may be administered.
  • P ⁇ i e ⁇ m ⁇ a ⁇ zhe m ⁇ zhe ⁇ ⁇ susches ⁇ vlya ⁇ sya ⁇ dn ⁇ v ⁇ emenn ⁇ e vy ⁇ esnenie is ⁇ dn ⁇ y mixture gaz ⁇ v bi ⁇ l ⁇ giches ⁇ g ⁇ ⁇ be ⁇ a ⁇ s ⁇ eds ⁇ v ⁇ m ⁇ idaniya ⁇ dn ⁇ mu of ⁇ m ⁇ nen ⁇ v mixture gaz ⁇ v b ⁇ lee vys ⁇ g ⁇ ⁇ a ⁇ tsialn ⁇ g ⁇ pressure than that of ⁇ dn ⁇ g ⁇ gaz ⁇ v, na ⁇ dyaschi ⁇ sya in ⁇ le ⁇ a ⁇ bi ⁇ l ⁇ giches ⁇ g ⁇ ⁇ be ⁇ a or ⁇ s ⁇ eds ⁇ v ⁇ m ⁇ nizheniya or ⁇ vysheniya pressure ⁇ uzhayuschey bi ⁇ l ⁇ g
  • the oxygen content in the food mixture is 12%.
  • one of the components contains a mixture of helium and / or arsenic, and / or other six hundred percent sulfur and / or methane and / or nitrous oxide or mixtures thereof.
  • the other A complete change in the quantity and quantity of the composition and / or physical characteristics of the substitute mixture.
  • ⁇ ⁇ ezul ⁇ a ⁇ e ⁇ i change ⁇ specify alg ⁇ i ⁇ mam ⁇ - tsess ⁇ v sa ⁇ u ⁇ atsii and desa ⁇ u ⁇ atsii, ⁇ azhdy of ⁇ y ⁇ ⁇ susches ⁇ v- lyae ⁇ sya in tsi ⁇ liches ⁇ m ⁇ ezhime, byl ⁇ ⁇ bna ⁇ uzhen ⁇ , ch ⁇ in ⁇ echenie even ⁇ dn ⁇ y ⁇ tsedu ⁇ y ⁇ is ⁇ di ⁇ a ⁇ yad ⁇ izi ⁇ l ⁇ giches ⁇ i ⁇ sdvig ⁇ v in ⁇ ganizme - changing ⁇ sm ⁇ iches ⁇ g ⁇ pressure lowering ⁇ g ⁇ v v ⁇ zbudim ⁇ s ⁇ i ⁇ le ⁇ , the world and so on, which, in the end, will facilitate the effective treatment of the gross impact on the economy and increase the profitability.
  • ⁇ g ⁇ m ⁇ zhn ⁇ is ⁇ lz ⁇ va ⁇ ⁇ i treatment b ⁇ n ⁇ - leg ⁇ chny ⁇ , se ⁇ dechn ⁇ -s ⁇ sudis ⁇ y ⁇ zab ⁇ levany in ⁇ m including ⁇ - niches ⁇ g ⁇ ⁇ a ⁇ a ⁇ e ⁇ a, ⁇ azaniya ⁇ e ⁇ v ⁇ y meditsins ⁇ y ⁇ m ⁇ schi in ⁇ aches ⁇ ve anes ⁇ ezii in ⁇ aches ⁇ ve ⁇ eabili ⁇ atsi ⁇ nn ⁇ g ⁇ s ⁇ eds ⁇ va in ⁇ sle ⁇ e ⁇ atsi ⁇ nny ⁇ e ⁇ i ⁇ d for snya ⁇ iya Sind ⁇ ma na ⁇ zavisi- m ⁇ s ⁇ i and d ⁇ ugi ⁇ sluchaya ⁇ , when the increase in the general resilience of the organism is required.
  • the process of exposure to the biological product with gas mixtures may occur with a genuine replacement of one gas mixture with another.
  • the same gases with other partial pressures or other gases listed above may be emitted.
  • P ⁇ i ⁇ imenenii mixtures gaz ⁇ v identified ⁇ a ⁇ zhe ⁇ a ⁇ ie ⁇ izi ⁇ - l ⁇ giches ⁇ ie e ⁇ e ⁇ y, ⁇ a ⁇ a ⁇ ivatsiya bi ⁇ ele ⁇ iches ⁇ y a ⁇ ivn ⁇ - s ⁇ i g ⁇ l ⁇ vn ⁇ g ⁇ m ⁇ zga, ⁇ davlenie vyb ⁇ s ⁇ v ⁇ a ⁇ e ⁇ alamin ⁇ v, a ⁇ - 5 ⁇ ivatsiya ⁇ anev ⁇ g ⁇ dy ⁇ aniya, and s ⁇ abilizatsiya ⁇ vyshenie ⁇ bscheg ⁇ immuni ⁇ e ⁇ a ⁇ ganizma.
  • the oxygen mixture is especially actual for its temperature.
  • P ⁇ d ⁇ g ⁇ ev mixture znachi ⁇ eln ⁇ above ⁇ em ⁇ e ⁇ a ⁇ u ⁇ y ⁇ ela ⁇ bes ⁇ echivae ⁇ ⁇ avn ⁇ me ⁇ n ⁇ s ⁇ and vys ⁇ uyu ⁇ da- chu ⁇ e ⁇ la in ⁇ v ⁇ dyaschi ⁇ ⁇ u ⁇ ya ⁇ and leg ⁇ chn ⁇ y ⁇ ani chel ⁇ ve ⁇ a, ⁇ a ⁇ bi ⁇ l ⁇ giches ⁇ g ⁇ ⁇ be ⁇ a, ⁇ i e ⁇ m ⁇ is ⁇ di ⁇ improvement ⁇ e ⁇ - l ⁇ giches ⁇ i ⁇ sv ⁇ ys ⁇ v m ⁇ y, ⁇ blegchenie its d ⁇ eni ⁇ vaniya, improvement in ⁇ a ⁇ illya ⁇ n ⁇ g ⁇ ⁇ v ⁇ a leg ⁇ i ⁇ and v ⁇ zbuzhdenie ⁇ e ⁇ m ⁇ - and schematics.
  • a mixture of gases containing oxygen and one or more of the listed gases is supplied to the human body during the course of the operation, while the unit is supplied with electricity; ⁇ emya ⁇ dachi m ⁇ zhe ⁇ by ⁇ vyb ⁇ an ⁇ ⁇ ⁇ dn ⁇ g ⁇ vd ⁇ a (4 ⁇ iblizi ⁇ eln ⁇ se ⁇ undy) d ⁇ chas ⁇ v 24, v ⁇ emya ⁇ e ⁇ e ⁇ y- va m ⁇ zhe ⁇ by ⁇ ⁇ a ⁇ im same - e ⁇ svyazan ⁇ with u ⁇ vnem v ⁇ zdeys ⁇ viya ⁇ azlichny ⁇ gaz ⁇ v on ⁇ aznye ⁇ ani and ⁇ iziches ⁇ im s ⁇ s ⁇ yaniem chel ⁇ ve ⁇ a, ade ⁇ va ⁇ nym eg ⁇ zab ⁇ levaniyu.
  • the duration of the mixture can be up to 5 seconds to 7 days.
  • an interesting content of the constituents of the gas mixture of the components is not limited.
  • the cyclic operating mode is individual.
  • the oxygen content in the mixture was 12%.
  • a gas mixture that is supplied to a biological product is injected through a smoke mask or through an intubation, or through a helmet, or an appliance, or This makes it possible to localize the impact of the process of destruction - the descent of 5 organisms by gas mixtures for any part or to distribute it for the whole.
  • ⁇ zm ⁇ zhn ⁇ s ⁇ administration mixture gaz ⁇ v che ⁇ ez dy ⁇ a ⁇ elnuyu large- ⁇ u or che ⁇ ez in ⁇ ubatsi ⁇ nnuyu ⁇ ub ⁇ u or che ⁇ ez helmet ⁇ dn ⁇ v ⁇ e- menn ⁇ with ⁇ vedeniem is ⁇ uss ⁇ venn ⁇ g ⁇ ⁇ v ⁇ b ⁇ ascheniya with saturated 0 scheniem ⁇ vi anes ⁇ ezi ⁇ uyuschim gaz ⁇ m ⁇ sen ⁇ n ⁇ m or ⁇ i ⁇ n ⁇ m, susches ⁇ venn ⁇ ⁇ asshi ⁇ yae ⁇ v ⁇ zm ⁇ zhn ⁇ s ⁇ i ⁇ imeneniya s ⁇ s ⁇ ba ⁇ i ⁇ vedenii ⁇ i ⁇ u ⁇ giches ⁇ i ⁇ ⁇ e ⁇ atsy.
  • the claimed invention was adopted as follows.
  • Example 3 A patient with a severe and mild deficiency in the presence of prolonged, malfunctioning and malfunctioning devices Patient 52 years old.
  • the patient was placed in a chamber filled with air in the environment of the surroundings.
  • the pressure medium of the environment was maintained at + 28 + 32 ° ⁇ , the pressure was up to 3 kgf / cm 2 . Impact on the patient under this pressure was carried out for 20 minutes. Then the patient was given an acid-helium gas mixture through a mask and doubled up to 1.2 kgf / cm 2 for 15 minutes, after which the mixture was discharged. atmospheric pressure. Thanks to this, there was a gradual settlement at first by one, and then by another gas.
  • the content of oxygen in gas mixtures was constant and equal to 23–25%.
  • Example 4 A patient with impaired abnormalities and mild deficiency was placed in the room. The patient was breathing in air and normal pressure. The barocamera was cut off and the pressure was reduced to - 0.6 kgf / cm 2 . At this pressure, the patient breathed with a relaxed air for 3-4 minutes and then the pressure returned to normal, after 5-6 minutes the procedure was performed 16
  • the propellant capacity has been restored and the capacity of the vessels has improved.
  • the control over the degree of catastrophe and the change in its parameters showed its significant impact on the state of the patient's illness.
  • Example 5 A group of five casualties was rehabilitated after a series of loads. They were led by placing the entire group in the bar. At first, the group breathed in air and normal pressure. Then, the pressure was dropped and the air pressure increased to 2.0 kgf / cm 2 . With this pressure, the group breathed compressed air for 10 minutes and, after this, they decompressed to normal pressure. 3-4 times were taken, with each subsequent time being kept under pressure, they were saved for 2 minutes. Delivery time - 3-5 days.
  • the inventive invention has received equipment with the involvement of specialists - medics.
  • the results of the treatment of patients with gas mixtures by the claimed method showed a very high efficiency as a result of treatment, treatment and treatment.
  • the inventive method removes a wide range of non-medicamentous treatment for patients, which plays a role for patients with allergic treatments. More than that, it is possible to treat various types of diseases, including allergic diseases. Good outcomes for treating and treating people with diabetes are good for treating them for a good and healthy outcome. 17

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  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention relève du domaine de la médecine et des équipements médicaux et peut être utilisée comme instrument de régulation de l'état physiologique d'un objet biologique à l'aide de mélanges gazeux. Le procédé de cette invention consiste à exposer l'objet biologique, préalablement placé dans un milieu contenant au moins un gaz, à l'action d'un mélange gazeux pendant au moins un processus, un des composants dudit mélange étant de l'oxygène ; puis à laisser le mélange gazeux agir sur l'objet biologique pendant un processus de manière cyclique afin de garantir la saturation et/ou la désaturation d'au moins un composant du mélange gazeux dans les cellules des tissus de l'objet biologique, la saturation et/ou la désaturation se produisant par la génération d'une différence de pression partielle entre un des composants du mélange gazeux actif et au moins un des composants du mélange gazeux initial dans les cellules des tissus de l'objet biologique, la saturation et/ou la désaturation se produisant de manière périodique. La présente invention permet d'améliorer les facultés d'adaptation d'un organisme aux changements de l'environnement, d'accroître la résistance générale de l'organisme et peut être utilisée comme instrument pour traiter des infections broncho-pulmonaires, des maladies cardiovasculaires et autres maladies, pour administrer les premiers soins ainsi que pour réaliser une anesthésie.
PCT/RU2002/000392 2002-08-20 2002-08-20 Procede de regulation de l'etat physiologique d'un objet biologique a l'aide de melanges gazeux WO2004018027A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002349379A AU2002349379A1 (en) 2002-08-20 2002-08-20 Method for regulating the physiological state of a biological object by gas mixtures
PCT/RU2002/000392 WO2004018027A1 (fr) 2002-08-20 2002-08-20 Procede de regulation de l'etat physiologique d'un objet biologique a l'aide de melanges gazeux

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PCT/RU2002/000392 WO2004018027A1 (fr) 2002-08-20 2002-08-20 Procede de regulation de l'etat physiologique d'un objet biologique a l'aide de melanges gazeux

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1721629A1 (fr) * 2005-02-18 2006-11-15 Oleg Bassovitch Procédé et appareil d'entrainement hypoxique intermittent

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182324A (en) * 1977-09-01 1980-01-08 Hills Brian A Diver gas safety valve
RU2072241C1 (ru) * 1995-09-20 1997-01-27 Панина Елена Владимировна Способ формирования дыхательной газовой смеси и аппарат для его осуществления
RU2146536C1 (ru) * 1999-04-16 2000-03-20 Специальное конструкторское бюро экспериментального оборудования при Государственном научном центре Российской Федерации "Институт медико-биологических проблем" Способ подготовки и подачи лечебной газовой смеси и устройство для его осуществления

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182324A (en) * 1977-09-01 1980-01-08 Hills Brian A Diver gas safety valve
RU2072241C1 (ru) * 1995-09-20 1997-01-27 Панина Елена Владимировна Способ формирования дыхательной газовой смеси и аппарат для его осуществления
RU2146536C1 (ru) * 1999-04-16 2000-03-20 Специальное конструкторское бюро экспериментального оборудования при Государственном научном центре Российской Федерации "Институт медико-биологических проблем" Способ подготовки и подачи лечебной газовой смеси и устройство для его осуществления

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AMINOV AKHMAD ABDUKADYROVICH: "Gazoobmen, gemodinamika i koagulyatsionnye svoistva krovi v kompleksnoi intensivnoi terapii astmaticheskogo sostoyaniya s primeneniem geny - kislorodnoi smesi, avtoreferat dissertatsii na soskani uchenoi stepeni kandidata meditsinskikh", NAUK, 1988, MOSCOW, pages 17 - 18 *
SHULAGIN JU. A. ET AL.: "Vliyanie argona na potreblenie kisloroda chelovekom pri fizicheskoi nagruzke v usloviyakh gipoksii, fiziologiya cheloveka", NAUKA, vol. 27, no. 1, 2001, pages 95 - 97 *
SHULUNOV MIKHAIL VLADIMIROVICH: "Otsenka alekvatnosti ksenanovoi anestezii po dannym gormonalnykh, gemodinamicheskikh i biokhimicheskikh pokazatelei, avtoreferat dissertatsii na soiskani uchenoi stepeni kandidata meditsinskikh", NAUK, 1995, MOSCOW, pages 22, 23 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1721629A1 (fr) * 2005-02-18 2006-11-15 Oleg Bassovitch Procédé et appareil d'entrainement hypoxique intermittent

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