WO2004003009A3 - Francisella tularensis immunogenic proteins and dna encoding these - Google Patents

Francisella tularensis immunogenic proteins and dna encoding these Download PDF

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Publication number
WO2004003009A3
WO2004003009A3 PCT/GB2003/002718 GB0302718W WO2004003009A3 WO 2004003009 A3 WO2004003009 A3 WO 2004003009A3 GB 0302718 W GB0302718 W GB 0302718W WO 2004003009 A3 WO2004003009 A3 WO 2004003009A3
Authority
WO
WIPO (PCT)
Prior art keywords
francisella tularensis
dna encoding
immunogenic proteins
proteins
protective
Prior art date
Application number
PCT/GB2003/002718
Other languages
French (fr)
Other versions
WO2004003009A2 (en
Inventor
Richard William Titball
Carl Nicholas Mayers
Melanie Lorraine Duffield
Julie Miller
Sonya Claire Rowe
Original Assignee
Secr Defence
Richard William Titball
Carl Nicholas Mayers
Melanie Lorraine Duffield
Julie Miller
Sonya Claire Rowe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Secr Defence, Richard William Titball, Carl Nicholas Mayers, Melanie Lorraine Duffield, Julie Miller, Sonya Claire Rowe filed Critical Secr Defence
Priority to AU2003236912A priority Critical patent/AU2003236912A1/en
Publication of WO2004003009A2 publication Critical patent/WO2004003009A2/en
Publication of WO2004003009A3 publication Critical patent/WO2004003009A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

Proteins and nucleic acids for use in producing a protective immune response in a mammal against infection by Francisella tularensis, are described and claimed. The proteins are selected from the SEQ ID NO 1-100 as provided in the application, or protective variants thereof, or fragments of either of these.
PCT/GB2003/002718 2002-06-28 2003-06-26 Francisella tularensis immunogenic proteins and dna encoding these WO2004003009A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003236912A AU2003236912A1 (en) 2002-06-28 2003-06-26 Francisella tularensis immunogenic proteins and dna encoding these

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0214942.5 2002-06-28
GBGB0214942.5A GB0214942D0 (en) 2002-06-28 2002-06-28 Immunogenic proteins and DNA encoding these

Publications (2)

Publication Number Publication Date
WO2004003009A2 WO2004003009A2 (en) 2004-01-08
WO2004003009A3 true WO2004003009A3 (en) 2004-02-26

Family

ID=9939448

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/002718 WO2004003009A2 (en) 2002-06-28 2003-06-26 Francisella tularensis immunogenic proteins and dna encoding these

Country Status (3)

Country Link
AU (1) AU2003236912A1 (en)
GB (1) GB0214942D0 (en)
WO (1) WO2004003009A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2502999A1 (en) * 2005-04-20 2006-10-20 National Research Council Of Canada Mutant f. tularensis strain and uses thereof
AT503530A1 (en) * 2006-04-28 2007-11-15 Biomay Ag POLYPEPTIDE WITH ALLERGENIC PROPERTIES
WO2008127296A2 (en) * 2006-10-25 2008-10-23 The Regents Of The University Of California Methods and compositions for treating tularemia
ATE487487T1 (en) * 2007-09-04 2010-11-15 Inst Nat Sante Rech Med USE OF COMPOUNDS THAT PREVENT THE EF-TU-NUCLEOLIN INTERACTION FOR PREVENTING OR TREATING TULAREMIA

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002018600A1 (en) * 2000-08-26 2002-03-07 The Secretary Of State For Defence Groes and groel homologs of francisella tularensis
WO2003073351A2 (en) * 2002-02-26 2003-09-04 The Secretary Of State For Defence Screening process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002018600A1 (en) * 2000-08-26 2002-03-07 The Secretary Of State For Defence Groes and groel homologs of francisella tularensis
WO2003073351A2 (en) * 2002-02-26 2003-09-04 The Secretary Of State For Defence Screening process

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FULOP MARK ET AL: "Role of two outer membrane antigens in the induction of protective immunity against Francisella tularensis strains of different virulence.", FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, vol. 13, no. 3, 1996, pages 245 - 247, XP002255306, ISSN: 0928-8244 *
HUBALEK MARTIN ET AL: "Towards proteome database of Francisella tularensis.", JOURNAL OF CHROMATOGRAPHY B, vol. 787, no. 1, 2003, pages 149 - 177, XP002255308, ISSN: 1387-2273 *
PRIOR R G ET AL: "Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4.", JOURNAL OF APPLIED MICROBIOLOGY, vol. 91, no. 4, October 2001 (2001-10-01), pages 614 - 620, XP002255307, ISSN: 1364-5072 *
SJOSTEDT A ET AL: "HUMORAL AND CELL-MEDIATED IMMUNITY IN MICE TO A 17-KILODALTON LIPOPROTEIN OF FRANCISELLA-TULARENSIS EXPRESSED BY SALMONELLA-TYPHIMURIUM", INFECTION AND IMMUNITY, vol. 60, no. 7, 1992, pages 2855 - 2862, XP008022379, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
AU2003236912A8 (en) 2004-01-19
AU2003236912A1 (en) 2004-01-19
WO2004003009A2 (en) 2004-01-08
GB0214942D0 (en) 2002-08-07

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