WO2004000233A3 - Algal gdp-mannose-3',5'-epimerases and methods of use thereof - Google Patents

Algal gdp-mannose-3',5'-epimerases and methods of use thereof Download PDF

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Publication number
WO2004000233A3
WO2004000233A3 PCT/US2003/019951 US0319951W WO2004000233A3 WO 2004000233 A3 WO2004000233 A3 WO 2004000233A3 US 0319951 W US0319951 W US 0319951W WO 2004000233 A3 WO2004000233 A3 WO 2004000233A3
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WO
WIPO (PCT)
Prior art keywords
epimerases
gdp
mannose
algal
methods
Prior art date
Application number
PCT/US2003/019951
Other languages
French (fr)
Other versions
WO2004000233A2 (en
Inventor
Thomas W Mcmullin
Susan Shuyun Peng
Original Assignee
Arkion Life Sciences Llc
Thomas W Mcmullin
Susan Shuyun Peng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arkion Life Sciences Llc, Thomas W Mcmullin, Susan Shuyun Peng filed Critical Arkion Life Sciences Llc
Priority to AU2003249364A priority Critical patent/AU2003249364A1/en
Publication of WO2004000233A2 publication Critical patent/WO2004000233A2/en
Publication of WO2004000233A3 publication Critical patent/WO2004000233A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

GDP-mannose-3',5'-epimerases from algae have been identified, isolated, purified, and/or cloned. Disclosed herein are algal GDP-mannose-3',5'-epimerases from any algae, including those of the genera Chlamydomonas, Prototheca, and Chlorella. Also disclosed herein are nucleic acid and amino acid sequences for algal GDP-mannose-3',5'-epimerases and the use thereof to produce genetically modified host cells, as well as in methods to produce L-galactose, ascorbic acid, or intermediate products in the ascorbic acid biosynthetic pathway.
PCT/US2003/019951 2002-06-25 2003-06-25 Algal gdp-mannose-3',5'-epimerases and methods of use thereof WO2004000233A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003249364A AU2003249364A1 (en) 2002-06-25 2003-06-25 Algal gdp-mannose-3',5'-epimerases and methods of use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39176302P 2002-06-25 2002-06-25
US60/391,763 2002-06-25

Publications (2)

Publication Number Publication Date
WO2004000233A2 WO2004000233A2 (en) 2003-12-31
WO2004000233A3 true WO2004000233A3 (en) 2004-03-25

Family

ID=30000750

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/019951 WO2004000233A2 (en) 2002-06-25 2003-06-25 Algal gdp-mannose-3',5'-epimerases and methods of use thereof

Country Status (2)

Country Link
AU (1) AU2003249364A1 (en)
WO (1) WO2004000233A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060234360A1 (en) * 2005-04-13 2006-10-19 Paola Branduardi Ascorbic acid production from D-glucose in yeast
WO2016143799A1 (en) * 2015-03-09 2016-09-15 国立大学法人名古屋大学 Translation enhancer for use in cell-free protein synthesis system and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002103001A1 (en) * 2001-06-15 2002-12-27 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Gdp-mannose-3',5'-epimerase and methods of use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002103001A1 (en) * 2001-06-15 2002-12-27 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Gdp-mannose-3',5'-epimerase and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ASAMIZU ET AL.: "Generation of expressed sequence tags from low-CO2 and high-CO2 adapted cells of chlamydomonas reinhardtii", DNA RESEARCH, vol. 7, no. 5, 2000, pages 305 - 307, XP002971460 *
WOLUCKA ET AL.: "Partial purification and identification of GDP-mannose 3",5"-epimerase of arabidopsis thaliana, a key enzyme of the plant vitamin C pathway", PROC. NATL. ACAD. SCI. USA, vol. 98, no. 26, 18 December 2001 (2001-12-18), pages 14843 - 14848, XP002221670 *

Also Published As

Publication number Publication date
AU2003249364A8 (en) 2004-01-06
WO2004000233A2 (en) 2003-12-31
AU2003249364A1 (en) 2004-01-06

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