WO2003102542A3 - Comparative proteomics of progressor and nonprogressor populations - Google Patents

Comparative proteomics of progressor and nonprogressor populations Download PDF

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Publication number
WO2003102542A3
WO2003102542A3 PCT/US2003/017149 US0317149W WO03102542A3 WO 2003102542 A3 WO2003102542 A3 WO 2003102542A3 US 0317149 W US0317149 W US 0317149W WO 03102542 A3 WO03102542 A3 WO 03102542A3
Authority
WO
WIPO (PCT)
Prior art keywords
nonprogressor
progressor
populations
comparative proteomics
disease
Prior art date
Application number
PCT/US2003/017149
Other languages
French (fr)
Other versions
WO2003102542A2 (en
Inventor
William E Rich
David D Ho
Linqi Zhang
Original Assignee
Ciphergen Biosystems Inc
Aaron Diamond Aids Res Ct
William E Rich
David D Ho
Linqi Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciphergen Biosystems Inc, Aaron Diamond Aids Res Ct, William E Rich, David D Ho, Linqi Zhang filed Critical Ciphergen Biosystems Inc
Priority to AU2003243350A priority Critical patent/AU2003243350A1/en
Publication of WO2003102542A2 publication Critical patent/WO2003102542A2/en
Publication of WO2003102542A3 publication Critical patent/WO2003102542A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention identifies polypeptide biomarkers of disease progression or nonprogression by comparative protein profiling of samples from progressors and nonprogressors subpopulations of a population exposed to the pathogen or sharing a risk facto causing the disease. The polypeptides, their ligands, and modulators find use as diagnostic, prognostic, and therapeutic agents.
PCT/US2003/017149 2002-05-31 2003-05-30 Comparative proteomics of progressor and nonprogressor populations WO2003102542A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003243350A AU2003243350A1 (en) 2002-05-31 2003-05-30 Comparative proteomics of progressor and nonprogressor populations

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US38442802P 2002-05-31 2002-05-31
US60/384,428 2002-05-31
US40559502P 2002-08-23 2002-08-23
US60/405,595 2002-08-23
US41241402P 2002-09-20 2002-09-20
US60/412,414 2002-09-20
US41239702P 2002-09-21 2002-09-21
US60/412,397 2002-09-21

Publications (2)

Publication Number Publication Date
WO2003102542A2 WO2003102542A2 (en) 2003-12-11
WO2003102542A3 true WO2003102542A3 (en) 2004-01-22

Family

ID=29716297

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/017149 WO2003102542A2 (en) 2002-05-31 2003-05-30 Comparative proteomics of progressor and nonprogressor populations

Country Status (2)

Country Link
AU (1) AU2003243350A1 (en)
WO (1) WO2003102542A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0514553D0 (en) * 2005-07-15 2005-08-24 Nonlinear Dynamics Ltd A method of analysing a representation of a separation pattern

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020174447A1 (en) * 2001-01-23 2002-11-21 Greenspan Ralph J. Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease
US20020192720A1 (en) * 2001-05-08 2002-12-19 Parker Kenneth C. Process for analyzing protein samples
US20030082818A1 (en) * 2001-07-12 2003-05-01 Automated Cell, Inc. Method and apparatus for monitoring of proteins and cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020174447A1 (en) * 2001-01-23 2002-11-21 Greenspan Ralph J. Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer's disease
US20020192720A1 (en) * 2001-05-08 2002-12-19 Parker Kenneth C. Process for analyzing protein samples
US20030082818A1 (en) * 2001-07-12 2003-05-01 Automated Cell, Inc. Method and apparatus for monitoring of proteins and cells

Also Published As

Publication number Publication date
WO2003102542A2 (en) 2003-12-11
AU2003243350A8 (en) 2003-12-19
AU2003243350A1 (en) 2003-12-19

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