WO2003099852A3 - Processus de derivatisation de peptides - Google Patents

Processus de derivatisation de peptides Download PDF

Info

Publication number
WO2003099852A3
WO2003099852A3 PCT/US2003/016644 US0316644W WO03099852A3 WO 2003099852 A3 WO2003099852 A3 WO 2003099852A3 US 0316644 W US0316644 W US 0316644W WO 03099852 A3 WO03099852 A3 WO 03099852A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptide
derivatization process
peptide derivatization
derivatizing
nucleophile
Prior art date
Application number
PCT/US2003/016644
Other languages
English (en)
Other versions
WO2003099852A2 (fr
Inventor
Kirk E Cryer
Daniel Strydom
Jin Seog Seo
Barton Holmquist
Fred W Wagner
Original Assignee
Restoragen Inc
Kirk E Cryer
Daniel Strydom
Jin Seog Seo
Barton Holmquist
Fred W Wagner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Restoragen Inc, Kirk E Cryer, Daniel Strydom, Jin Seog Seo, Barton Holmquist, Fred W Wagner filed Critical Restoragen Inc
Priority to AU2003240796A priority Critical patent/AU2003240796A1/en
Publication of WO2003099852A2 publication Critical patent/WO2003099852A2/fr
Publication of WO2003099852A3 publication Critical patent/WO2003099852A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/126—Aminolysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un procédé de dérivatisation d'un peptide ayant un groupe Cys-His à sa terminaison carboxyle, selon lequel il est prévu de faire réagir ledit peptide à un pH supérieur à 10 ou davantage, avec un réactif bisulfure et un agent de cyanylation en présence d'un nucléophile.
PCT/US2003/016644 2002-05-24 2003-05-23 Processus de derivatisation de peptides WO2003099852A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003240796A AU2003240796A1 (en) 2002-05-24 2003-05-23 Peptide derivatization process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38336402P 2002-05-24 2002-05-24
US60/383,364 2002-05-24

Publications (2)

Publication Number Publication Date
WO2003099852A2 WO2003099852A2 (fr) 2003-12-04
WO2003099852A3 true WO2003099852A3 (fr) 2004-07-08

Family

ID=29584554

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/016644 WO2003099852A2 (fr) 2002-05-24 2003-05-23 Processus de derivatisation de peptides

Country Status (2)

Country Link
AU (1) AU2003240796A1 (fr)
WO (1) WO2003099852A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4085139A4 (fr) * 2020-01-03 2023-11-29 The Texas A&M University System Technique de ligature de polypeptide dirigée par la cystéine activée

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985627A (en) * 1997-02-28 1999-11-16 Carlsberg Laboratory Modified carboxypeptidase
US6051399A (en) * 1994-12-07 2000-04-18 Bionebraska, Inc. Production of C-terminal amidated peptides from recombinant protein constructs

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051399A (en) * 1994-12-07 2000-04-18 Bionebraska, Inc. Production of C-terminal amidated peptides from recombinant protein constructs
US5985627A (en) * 1997-02-28 1999-11-16 Carlsberg Laboratory Modified carboxypeptidase

Also Published As

Publication number Publication date
AU2003240796A1 (en) 2003-12-12
AU2003240796A8 (en) 2003-12-12
WO2003099852A2 (fr) 2003-12-04

Similar Documents

Publication Publication Date Title
AU2003253804A1 (en) Statically speculative compilation and execution
AU2002331258A1 (en) Perfluoroalkyl-substituted amines, acids, amino acids and thioether acids
AU4402093A (en) Debugger program which includes correlation of computer program source code with optimized objet code
AU2003278585A1 (en) Automatic, real time and complete identification of vehicles
AU2003216350A1 (en) Pointer identification and automatic data prefetch
AU2002324144A1 (en) Pipeline inspection pigs
AU2002359638A1 (en) Systems and methods for durable goods futures market
EP1321856A3 (fr) Système et méthode pour exécuter des applications multiples
WO2002042735A3 (fr) Regulation par kcr1 humaine de bloc de canal potassique herg
CA2207723A1 (fr) Methode d'elimination de groupe n-terminal de la methionine
EP1520177B8 (fr) Procede et reactif destines a l'identification specifique et a la quantification d'au moins une proteine dans un echantillon
AU2003250661A1 (en) Quantitative analysis via isotopically differentitated derivatization
WO2003099852A3 (fr) Processus de derivatisation de peptides
EP1533296A4 (fr) Compose sulfenyle, reactif de marquage. et procede d'analyse de peptide
AU7326201A (en) Process and architecture for xml-based insurance marketplace
AU2002224060A1 (en) Novel fructosyl amino acid oxidase
IT1284742B1 (it) Elemento per valvola a sfera e metodo per la sua fabbricazione.
AU2003253809A1 (en) Method for metal analysis and speciation and biosensor for effecting the method
WO2004101233A3 (fr) Outil pour encocher un tuyau
AU2003252383A1 (en) Test piece for protein assay and process for producing the same
AU2002351965A1 (en) Data flow-analyser and method for analysing programs
WO2004029117A3 (fr) Compositions de polyurethanne derives presentant une stabilite amelioree dans des systemes biologiques et procedes de preparation de ces compositions
AU2003216772A1 (en) Nucleic acid molecule encoding a variant ddah 1 protein and uses thereof
AU9075798A (en) Method for identifying and locating expressed epil peptides, coded by the insl4 gene and their uses
AU2002257766A1 (en) A novel zinc finger protein and uses thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 69(1) EPC

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

122 Ep: pct application non-entry in european phase