WO2003090600A3 - Compositions and methods for the diagnosis and treatment of tumor - Google Patents

Compositions and methods for the diagnosis and treatment of tumor Download PDF

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Publication number
WO2003090600A3
WO2003090600A3 PCT/US2002/012619 US0212619W WO03090600A3 WO 2003090600 A3 WO2003090600 A3 WO 2003090600A3 US 0212619 W US0212619 W US 0212619W WO 03090600 A3 WO03090600 A3 WO 03090600A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
tumor
diagnosis
treatment
methods
Prior art date
Application number
PCT/US2002/012619
Other languages
French (fr)
Other versions
WO2003090600A2 (en
Inventor
Avi J Ashkenazi
Dan L Eaton
Audrey Goddard
Austin L Gurney
William I Wood
Thomas D Wu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Priority to PCT/US2002/012619 priority Critical patent/WO2003090600A2/en
Priority to AU2002303430A priority patent/AU2002303430A1/en
Publication of WO2003090600A2 publication Critical patent/WO2003090600A2/en
Publication of WO2003090600A3 publication Critical patent/WO2003090600A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
PCT/US2002/012619 2002-04-23 2002-04-23 Compositions and methods for the diagnosis and treatment of tumor WO2003090600A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/US2002/012619 WO2003090600A2 (en) 2002-04-23 2002-04-23 Compositions and methods for the diagnosis and treatment of tumor
AU2002303430A AU2002303430A1 (en) 2002-04-23 2002-04-23 Compositions and methods for the diagnosis and treatment of tumor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/012619 WO2003090600A2 (en) 2002-04-23 2002-04-23 Compositions and methods for the diagnosis and treatment of tumor

Publications (2)

Publication Number Publication Date
WO2003090600A2 WO2003090600A2 (en) 2003-11-06
WO2003090600A3 true WO2003090600A3 (en) 2004-08-19

Family

ID=29268416

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/012619 WO2003090600A2 (en) 2002-04-23 2002-04-23 Compositions and methods for the diagnosis and treatment of tumor

Country Status (2)

Country Link
AU (1) AU2002303430A1 (en)
WO (1) WO2003090600A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846545A (en) * 1992-03-25 1998-12-08 Immunogen, Inc. Targeted delivery of cyclopropylbenzindole-containing cytotoxic drugs
WO2000061756A2 (en) * 1999-04-09 2000-10-19 Corixa Corporation Compounds for immunotherapy and diagnosis of breast cancer and methods for their use
WO2000073454A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846545A (en) * 1992-03-25 1998-12-08 Immunogen, Inc. Targeted delivery of cyclopropylbenzindole-containing cytotoxic drugs
WO2000061756A2 (en) * 1999-04-09 2000-10-19 Corixa Corporation Compounds for immunotherapy and diagnosis of breast cancer and methods for their use
WO2000073454A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BORREBAECK: "Antibody engineering", 1992, article GILLIES S.D.: "Design of expression vectors and mammalian cell sustems suitable for engineered antibody", pages: 139 *
BORREBAECK: "Antibody engineering", 1992, article WARD E.S.: "Expression and purification of antibody fragments using Escherichia coli as host", pages: 121 *
HARRIS ET AL: "Therapeutic antibodies - the coming of age", TIBTECH, vol. 11, February 1993 (1993-02-01), pages 42 - 44, XP000561907 *

Also Published As

Publication number Publication date
AU2002303430A1 (en) 2003-11-10
WO2003090600A2 (en) 2003-11-06
AU2002303430A8 (en) 2003-11-10

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