WO2003089570A3 - CRYSTALS AND STRUCTURES OF CMP-KDO SYNTHETASE KdoPS or CKS - Google Patents
CRYSTALS AND STRUCTURES OF CMP-KDO SYNTHETASE KdoPS or CKS Download PDFInfo
- Publication number
- WO2003089570A3 WO2003089570A3 PCT/US2002/035130 US0235130W WO03089570A3 WO 2003089570 A3 WO2003089570 A3 WO 2003089570A3 US 0235130 W US0235130 W US 0235130W WO 03089570 A3 WO03089570 A3 WO 03089570A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- kdops
- cks
- cmp
- crystals
- structures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002367784A AU2002367784A1 (en) | 2001-11-02 | 2002-11-01 | CRYSTALS AND STRUCTURES OF CMP-KDO SYNTHETASE KdoPS or CKS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33802501P | 2001-11-02 | 2001-11-02 | |
US60/338,025 | 2001-11-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003089570A2 WO2003089570A2 (en) | 2003-10-30 |
WO2003089570A3 true WO2003089570A3 (en) | 2007-02-22 |
Family
ID=29250439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/035130 WO2003089570A2 (en) | 2001-11-02 | 2002-11-01 | CRYSTALS AND STRUCTURES OF CMP-KDO SYNTHETASE KdoPS or CKS |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002367784A1 (en) |
WO (1) | WO2003089570A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116579271B (en) * | 2023-07-13 | 2024-03-29 | 中国空气动力研究与发展中心计算空气动力研究所 | Wall function correction method and device based on Cartesian grid |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5856116A (en) * | 1994-06-17 | 1999-01-05 | Vertex Pharmaceuticals, Incorporated | Crystal structure and mutants of interleukin-1 beta converting enzyme |
-
2002
- 2002-11-01 AU AU2002367784A patent/AU2002367784A1/en not_active Abandoned
- 2002-11-01 WO PCT/US2002/035130 patent/WO2003089570A2/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5856116A (en) * | 1994-06-17 | 1999-01-05 | Vertex Pharmaceuticals, Incorporated | Crystal structure and mutants of interleukin-1 beta converting enzyme |
Non-Patent Citations (9)
Title |
---|
ASOJO ET AL.: "Crystal structure of KDOP synthase in its binary complex with the substrate phosphenolpyruvate and with mechanism based inhibitor", BIOCHEMISTRY, vol. 40, no. 21, 29 May 2001 (2001-05-29), pages 6326 - 6334, XP003008277 * |
BIRCK ET AL.: "Aquifex aeolicus 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase: a new class of KDO 8-P synthase", J. MOL. EVOL., vol. 52, no. 2, February 2001 (2001-02-01), pages 205 - 214, XP003008337 * |
COHEN ET AL.: "Molecular modeling software and methods for medicinal chemistry", J. MED. CHEM., vol. 3, no. 3, March 1990 (1990-03-01), pages 883 - 894, XP002950820 * |
DATABASE PROTEIN [online] 16 May 2001 (2001-05-16), ASOJO ET AL.: "Crystal structure of KDO8P in a binary complex with mechanical based inhibitor", XP003008335, Database accession no. (1G7V) * |
DATABASE PROTEIN [online] 16 May 2001 (2001-05-16), ASOJO ET AL.: "Crystal structure of KDO8P in its binary complex with substrate phosphenol pyruvate", XP003008336, Database accession no. (1G7U) * |
DATABASE PROTEIN [online] 4 October 2000 (2000-10-04), WAGNER ET AL.: "Crystal structure of KDOP synthase", XP003008334, Database accession no. (1GG0) * |
FLEISCHMANN ET AL.: "Whole-genome random sequencing and assembly of Haemophilus influenza Rd", SCIENCE, vol. 269, 1995, pages 496 - 512, XP002916664 * |
KIRKPATRICK ET AL.: "Structure-based drug design: combinatorial chemistry and molecular modeling", COMB. CHEM. HIGH THROU. SCR., vol. 2, 1999, pages 211 - 221, XP001094530 * |
WAGNER ET AL.: "3-Deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli. Model of binding of phosphoenolpyruvate and D-arabinose-5-phosphate", vol. 301, 11 August 2000 (2000-08-11), pages 233 - 238, XP004480430 * |
Also Published As
Publication number | Publication date |
---|---|
AU2002367784A1 (en) | 2003-11-03 |
WO2003089570A2 (en) | 2003-10-30 |
AU2002367784A8 (en) | 2003-11-03 |
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