WO2003086456A3 - Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer - Google Patents
Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer Download PDFInfo
- Publication number
- WO2003086456A3 WO2003086456A3 PCT/CA2003/000500 CA0300500W WO03086456A3 WO 2003086456 A3 WO2003086456 A3 WO 2003086456A3 CA 0300500 W CA0300500 W CA 0300500W WO 03086456 A3 WO03086456 A3 WO 03086456A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cancer
- antibodies
- therapeutic
- monoclonal antibody
- diagnostic uses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003227148A AU2003227148A1 (en) | 2002-04-05 | 2003-04-07 | Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37065902P | 2002-04-05 | 2002-04-05 | |
US60/370,659 | 2002-04-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003086456A2 WO2003086456A2 (en) | 2003-10-23 |
WO2003086456A3 true WO2003086456A3 (en) | 2003-12-04 |
Family
ID=29250562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CA2003/000500 WO2003086456A2 (en) | 2002-04-05 | 2003-04-07 | Anti-ck18 monoclonal antibody and therapeutic and diagnostic uses thereof in cancer |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2003227148A1 (en) |
WO (1) | WO2003086456A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7442777B2 (en) | 2000-11-29 | 2008-10-28 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD63 |
US7534429B2 (en) | 2000-11-29 | 2009-05-19 | Hoffmann-La Roche Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD63 |
US7431923B2 (en) | 2005-01-03 | 2008-10-07 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD63 |
US7361343B2 (en) | 2003-01-21 | 2008-04-22 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of CD63 |
US7009040B2 (en) * | 2003-01-21 | 2006-03-07 | Arius Research, Inc. | Cancerous disease modifying antibodies |
US7393531B2 (en) * | 2003-01-21 | 2008-07-01 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of MCSP |
US7468254B2 (en) | 2003-01-21 | 2008-12-23 | Arius Research Inc. | Cytotoxicity mediation of cells evidencing surface expression of MCSP |
US7361342B2 (en) * | 2003-01-21 | 2008-04-22 | Arius Research Inc. | Cancerous disease modifying antibodies |
US7399835B2 (en) * | 2004-02-26 | 2008-07-15 | Arius Research Inc. | Cancerous disease modifying antibodies |
US7452978B2 (en) * | 2005-08-02 | 2008-11-18 | Arius Research, Inc. | Cancerous disease modifying antibodies |
US7494648B2 (en) * | 2005-08-02 | 2009-02-24 | Hoffmann-La Roche Inc. | Cancerous disease modifying antibodies |
US7456258B2 (en) * | 2005-08-02 | 2008-11-25 | Arius Research, Inc. | Cancerous disease modifying antibodies |
US7411046B2 (en) * | 2005-08-02 | 2008-08-12 | Arius Research Inc | Cancerous disease modifying antibodies |
US7452979B2 (en) * | 2005-08-02 | 2008-11-18 | Arius Research, Inc. | Cancerous disease modifying antibodies |
US7456259B2 (en) * | 2005-08-02 | 2008-11-25 | Arius Research, Inc. | Cancerous disease modifying antibodies |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031728A1 (en) * | 1994-05-17 | 1995-11-23 | Beki Ab | Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies |
US6180357B1 (en) * | 1999-10-08 | 2001-01-30 | Arius Research, Inc. | Individualized patient-specific anti-cancer antibodies |
WO2003057168A2 (en) * | 2002-01-03 | 2003-07-17 | The Scripps Research Institute | Cancer-associated epitope |
-
2003
- 2003-04-07 WO PCT/CA2003/000500 patent/WO2003086456A2/en not_active Application Discontinuation
- 2003-04-07 AU AU2003227148A patent/AU2003227148A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995031728A1 (en) * | 1994-05-17 | 1995-11-23 | Beki Ab | Method of detecting cancer involving fragments of cytokeratin 18 and corresponding antibodies |
US6180357B1 (en) * | 1999-10-08 | 2001-01-30 | Arius Research, Inc. | Individualized patient-specific anti-cancer antibodies |
WO2003057168A2 (en) * | 2002-01-03 | 2003-07-17 | The Scripps Research Institute | Cancer-associated epitope |
Non-Patent Citations (2)
Title |
---|
ETO HIROSHI ET AL: "Mapping and regulation of the tumor-associated epitope recognized by monoclonal antibody RS-11.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 35, 1 September 2000 (2000-09-01), pages 27075 - 27083, XP002254882, ISSN: 0021-9258 * |
SASAKI M ET AL: "Immunoperoxidase staining for cytokeratins 8 and 18 is very sensitive for detection of occult node metastasis of colorectal cancer: A comparison with genetic analysis of K-ras.", HISTOPATHOLOGY (OXFORD), vol. 32, no. 3, March 1998 (1998-03-01), pages 199 - 208, XP002254883, ISSN: 0309-0167 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003227148A8 (en) | 2003-10-27 |
WO2003086456A2 (en) | 2003-10-23 |
AU2003227148A1 (en) | 2003-10-27 |
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