WO2003078048A3 - Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung - Google Patents

Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung Download PDF

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Publication number
WO2003078048A3
WO2003078048A3 PCT/DE2003/000891 DE0300891W WO03078048A3 WO 2003078048 A3 WO2003078048 A3 WO 2003078048A3 DE 0300891 W DE0300891 W DE 0300891W WO 03078048 A3 WO03078048 A3 WO 03078048A3
Authority
WO
WIPO (PCT)
Prior art keywords
microcapsules
support particles
production
isolation
support material
Prior art date
Application number
PCT/DE2003/000891
Other languages
English (en)
French (fr)
Other versions
WO2003078048A2 (de
Inventor
Holger Woehlecke
Rudolf Ehwald
Dietmar Lerche
Original Assignee
L U M Gmbh
Holger Woehlecke
Rudolf Ehwald
Dietmar Lerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L U M Gmbh, Holger Woehlecke, Rudolf Ehwald, Dietmar Lerche filed Critical L U M Gmbh
Priority to AU2003221605A priority Critical patent/AU2003221605A1/en
Priority to AT03717154T priority patent/ATE310577T1/de
Priority to EP03717154A priority patent/EP1487571B1/de
Priority to DE50301747T priority patent/DE50301747D1/de
Publication of WO2003078048A2 publication Critical patent/WO2003078048A2/de
Publication of WO2003078048A3 publication Critical patent/WO2003078048A3/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B01J20/28021—Hollow particles, e.g. hollow spheres, microspheres or cenospheres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

Die Erfindung betrifft Trägerpartikeln für die Chromatographie auf der Grundlage von Mikrokapseln mit poröser Wand, Verfahren zu ihrer Herstellung und ihre Verwendung. Die erfindungsgemässen Trägerpartikeln stellen Mikrokapseln mit einer druckfesten und gleichzeitig für Makromoleküle hochdurchlässigen Wand dar oder enthalten solche Mikrokapseln. Das Trägermaterial kann insbesondere aus gereinigten Exinen von Koniferenpollen bestehen. Dieses Trägermaterial ist für chromatographische Anwendungen besonders geeignet, wo es auf den schnellen Austausch von Polymermolekülen der Grösse von Proteinen und Polymermolekülen bis zu einer bestimmten Teilchengrösse, die zweihundert nm betragen kann, mit der stationären Flüssigphase ankommt. Wichtige Anwendungen bestehen in der Isolation genomischer DNA aus einem Rohextrakt oder der Abtrennung einer besonders hochmolekularen Fraktion von kleineren Molekülen einer polydispersen Polymermischung.
PCT/DE2003/000891 2002-03-14 2003-03-13 Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung WO2003078048A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2003221605A AU2003221605A1 (en) 2002-03-14 2003-03-13 Support particles for chromatography based on microcapsules, method for their production and use thereof
AT03717154T ATE310577T1 (de) 2002-03-14 2003-03-13 Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung
EP03717154A EP1487571B1 (de) 2002-03-14 2003-03-13 Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung
DE50301747T DE50301747D1 (de) 2002-03-14 2003-03-13 Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10211300.9 2002-03-14
DE10211300 2002-03-14

Publications (2)

Publication Number Publication Date
WO2003078048A2 WO2003078048A2 (de) 2003-09-25
WO2003078048A3 true WO2003078048A3 (de) 2003-12-18

Family

ID=27815643

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2003/000891 WO2003078048A2 (de) 2002-03-14 2003-03-13 Trägerpartikeln für die chromatographie auf der grundlage von mikrokapseln, verfahren zu ihrer herstellung und ihre anwendung

Country Status (5)

Country Link
EP (1) EP1487571B1 (de)
AT (1) ATE310577T1 (de)
AU (1) AU2003221605A1 (de)
DE (3) DE10312128A1 (de)
WO (1) WO2003078048A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7608270B2 (en) 2003-06-27 2009-10-27 University Of Hull Dosage form
AU2006273842B2 (en) 2005-07-28 2012-02-02 University Of Hull Topical formulations containing sporopollenin
GB0812513D0 (en) 2008-07-09 2008-08-13 Univ Hull Delivery vehicle
CN110433741B (zh) * 2019-07-08 2022-01-14 浙江工业大学 一种具有碳骨架的芳香抗菌微胶囊及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4257884A (en) * 1979-04-17 1981-03-24 Damon Corporation Chromatography
DE3347512A1 (de) * 1983-01-14 1984-07-19 Humboldt-Universität zu Berlin, DDR 1080 Berlin Vesikulaeres trenn-, fuell- und traegermaterial
US4698317A (en) * 1984-04-24 1987-10-06 Kanto Kagaku Kabushiki Kaisha Porous cordierite ceramics, a process for producing same and use of the porous cordierite ceramics
DE3821619A1 (de) * 1987-08-11 1989-02-23 Petrolchemisches Kombinat Vesikulaere fuellkoerper fuer die chromatographie aus denaturierten mikroorganismen und verfahren zur herstellung
US5770416A (en) * 1989-05-26 1998-06-23 Upfront Chromatography A/S Permeable hollow particles having an outer shell of mechanically rigid porous material
DE19902724A1 (de) * 1999-01-19 2000-07-27 Dietmar Lerche Mikrokapseln aus Sporopollenin, Verfahren zu ihrer Herstellung und Anwendung

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4257884A (en) * 1979-04-17 1981-03-24 Damon Corporation Chromatography
DE3347512A1 (de) * 1983-01-14 1984-07-19 Humboldt-Universität zu Berlin, DDR 1080 Berlin Vesikulaeres trenn-, fuell- und traegermaterial
US4698317A (en) * 1984-04-24 1987-10-06 Kanto Kagaku Kabushiki Kaisha Porous cordierite ceramics, a process for producing same and use of the porous cordierite ceramics
DE3821619A1 (de) * 1987-08-11 1989-02-23 Petrolchemisches Kombinat Vesikulaere fuellkoerper fuer die chromatographie aus denaturierten mikroorganismen und verfahren zur herstellung
US5770416A (en) * 1989-05-26 1998-06-23 Upfront Chromatography A/S Permeable hollow particles having an outer shell of mechanically rigid porous material
DE19902724A1 (de) * 1999-01-19 2000-07-27 Dietmar Lerche Mikrokapseln aus Sporopollenin, Verfahren zu ihrer Herstellung und Anwendung

Also Published As

Publication number Publication date
AU2003221605A1 (en) 2003-09-29
DE10312128A1 (de) 2003-10-30
DE20304380U1 (de) 2003-09-11
DE50301747D1 (de) 2005-12-29
EP1487571B1 (de) 2005-11-23
AU2003221605A8 (en) 2003-09-29
ATE310577T1 (de) 2005-12-15
WO2003078048A2 (de) 2003-09-25
EP1487571A2 (de) 2004-12-22

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