WO2003077875A3 - Proteines associees a la croissance, a la differenciation et a la mort cellulaires - Google Patents

Proteines associees a la croissance, a la differenciation et a la mort cellulaires Download PDF

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Publication number
WO2003077875A3
WO2003077875A3 PCT/US2003/008310 US0308310W WO03077875A3 WO 2003077875 A3 WO2003077875 A3 WO 2003077875A3 US 0308310 W US0308310 W US 0308310W WO 03077875 A3 WO03077875 A3 WO 03077875A3
Authority
WO
WIPO (PCT)
Prior art keywords
death
differentiation
cgdd
proteins associated
growth
Prior art date
Application number
PCT/US2003/008310
Other languages
English (en)
Other versions
WO2003077875A2 (fr
Inventor
Amy E Kable
Uyen K Tran
April J A Hafalia
Neil Burford
Cynthia D Honchell
Patricia M Lehr-Mason
Brendan M Duggan
Jayalaxmi Ramkumar
Jennifer A Griffin
Thomas W Richardson
Vicki S Elliott
Xin Jiang
Alan A Jackson
Joseph P Marquis
Narinder K Chawla
Reena Khare
Shanya D Becha
Soo Yeun Lee
Anita Swarnakar
Henry Yue
Bridget A Warren
Mariah R Baughn
Preeti G Lal
Sally Lee
Anne Ho
Ameena R Gandhi
Monique G Yao
Original Assignee
Incyte Corp
Amy E Kable
Uyen K Tran
April J A Hafalia
Neil Burford
Cynthia D Honchell
Patricia M Lehr-Mason
Brendan M Duggan
Jayalaxmi Ramkumar
Jennifer A Griffin
Thomas W Richardson
Vicki S Elliott
Xin Jiang
Alan A Jackson
Joseph P Marquis
Narinder K Chawla
Reena Khare
Shanya D Becha
Soo Yeun Lee
Anita Swarnakar
Henry Yue
Bridget A Warren
Mariah R Baughn
Preeti G Lal
Sally Lee
Anne Ho
Ameena R Gandhi
Monique G Yao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp, Amy E Kable, Uyen K Tran, April J A Hafalia, Neil Burford, Cynthia D Honchell, Patricia M Lehr-Mason, Brendan M Duggan, Jayalaxmi Ramkumar, Jennifer A Griffin, Thomas W Richardson, Vicki S Elliott, Xin Jiang, Alan A Jackson, Joseph P Marquis, Narinder K Chawla, Reena Khare, Shanya D Becha, Soo Yeun Lee, Anita Swarnakar, Henry Yue, Bridget A Warren, Mariah R Baughn, Preeti G Lal, Sally Lee, Anne Ho, Ameena R Gandhi, Monique G Yao filed Critical Incyte Corp
Priority to AU2003218238A priority Critical patent/AU2003218238A1/en
Publication of WO2003077875A2 publication Critical patent/WO2003077875A2/fr
Publication of WO2003077875A3 publication Critical patent/WO2003077875A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Dans divers modes de réalisation, l'invention concerne des protéines humaines associées à la croissance, à la différenciation et à la mort cellulaires (CGDD) ainsi que des polynucléotides identifiant ces protéines CGDD et codant pour celles-ci. Dans certains modes de réalisation, l'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Dans d'autres modes de réalisation, elle se rapporte à des méthodes destinées à diagnostiquer, traiter ou prévenir des troubles associés à l'expression aberrante des protéines CGDD.
PCT/US2003/008310 2002-03-15 2003-03-14 Proteines associees a la croissance, a la differenciation et a la mort cellulaires WO2003077875A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003218238A AU2003218238A1 (en) 2002-03-15 2003-03-14 Proteins associated with growth, differentiation, and death

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US36449402P 2002-03-15 2002-03-15
US60/364,494 2002-03-15
US36912902P 2002-03-29 2002-03-29
US60/369,129 2002-03-29
US37251102P 2002-04-12 2002-04-12
US60/372,511 2002-04-12

Publications (2)

Publication Number Publication Date
WO2003077875A2 WO2003077875A2 (fr) 2003-09-25
WO2003077875A3 true WO2003077875A3 (fr) 2006-03-02

Family

ID=28046510

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/008310 WO2003077875A2 (fr) 2002-03-15 2003-03-14 Proteines associees a la croissance, a la differenciation et a la mort cellulaires

Country Status (2)

Country Link
AU (1) AU2003218238A1 (fr)
WO (1) WO2003077875A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7258988B2 (en) 2002-04-05 2007-08-21 Millennium Pharmaceuticals, Inc. Identification of a family of secreted proteins in vascular endothelium
WO2004016732A2 (fr) * 2002-04-29 2004-02-26 The Trustees Of Columbia University In The City Of New York Gènes à modulation d'astrocyte et leurs utilisations
WO2005050198A2 (fr) * 2003-11-13 2005-06-02 The Burnham Institute Polypeptides de metadherine codant des acides nucleiques et procedes d'utilisation
CN101283279A (zh) 2005-07-29 2008-10-08 肿瘤疗法科学股份有限公司 以cdca1-kntc2复合物为靶标的筛选和nsclc治疗方法
CA2810928A1 (fr) 2010-09-22 2012-03-29 Alios Biopharma, Inc. Analogues nucleotidiques substitues
AU2012358804B2 (en) 2011-12-22 2018-04-19 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
US9012427B2 (en) 2012-03-22 2015-04-21 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047750A1 (fr) * 1996-06-10 1997-12-18 Immunex Corporation KINASE 'ITAK' ACTIVEE PAR INTERLEUKINE-1 OU FACTEUR DE NECROSE TUMORALE α ET PROCEDES CORRESPONDANTS DE FABRICATION ET D'UTILISATION
US6080557A (en) * 1996-06-10 2000-06-27 Immunex Corporation IL-1/TNF-α-activated kinase (ITAK), and methods of making and using the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047750A1 (fr) * 1996-06-10 1997-12-18 Immunex Corporation KINASE 'ITAK' ACTIVEE PAR INTERLEUKINE-1 OU FACTEUR DE NECROSE TUMORALE α ET PROCEDES CORRESPONDANTS DE FABRICATION ET D'UTILISATION
US6080557A (en) * 1996-06-10 2000-06-27 Immunex Corporation IL-1/TNF-α-activated kinase (ITAK), and methods of making and using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug

Also Published As

Publication number Publication date
AU2003218238A1 (en) 2003-09-29
WO2003077875A2 (fr) 2003-09-25
AU2003218238A8 (en) 2003-09-29

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