WO2003072128A8 - Procedes et composes destines a traiter des defauts osseux ou du cartilage - Google Patents
Procedes et composes destines a traiter des defauts osseux ou du cartilageInfo
- Publication number
- WO2003072128A8 WO2003072128A8 PCT/US2003/005200 US0305200W WO03072128A8 WO 2003072128 A8 WO2003072128 A8 WO 2003072128A8 US 0305200 W US0305200 W US 0305200W WO 03072128 A8 WO03072128 A8 WO 03072128A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- defect
- compositions
- site
- growth factors
- methods
- Prior art date
Links
- 230000007547 defect Effects 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 4
- 210000000988 bone and bone Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 210000000845 cartilage Anatomy 0.000 title abstract 2
- 239000003102 growth factor Substances 0.000 abstract 5
- 210000001519 tissue Anatomy 0.000 abstract 4
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 208000015100 cartilage disease Diseases 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003219830A AU2003219830A1 (en) | 2002-02-22 | 2003-02-21 | Methods and compositions for treating bone or cartilage defects |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35877202P | 2002-02-22 | 2002-02-22 | |
US60/358,772 | 2002-02-22 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003072128A2 WO2003072128A2 (fr) | 2003-09-04 |
WO2003072128A3 WO2003072128A3 (fr) | 2003-12-31 |
WO2003072128A8 true WO2003072128A8 (fr) | 2004-03-11 |
Family
ID=27765991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/005200 WO2003072128A2 (fr) | 2002-02-22 | 2003-02-21 | Procedes et composes destines a traiter des defauts osseux ou du cartilage |
Country Status (3)
Country | Link |
---|---|
US (1) | US20030180270A1 (fr) |
AU (1) | AU2003219830A1 (fr) |
WO (1) | WO2003072128A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070148144A1 (en) * | 2005-10-27 | 2007-06-28 | Mason James M | Gene-enhanced tissue engineering |
EP1964583A1 (fr) | 2007-02-09 | 2008-09-03 | Royal College of Surgeons in Ireland | Processus de production d'une base composite de collagène/hydroxyapatite |
FR2948286B1 (fr) * | 2009-07-27 | 2011-08-26 | Jean-Noel Thorel | Composition injectable associant un agent de comblement et un milieu de croissance des fibroblastes |
FR2954165B1 (fr) * | 2009-12-18 | 2012-01-13 | Jean-Noel Thorel | Compositions injectables a usage intra-articulaire associant un agent de viscosupplementation et un milieu de croissance des fibroblastes |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
US5510254A (en) * | 1986-04-18 | 1996-04-23 | Advanced Tissue Sciences, Inc. | Three dimensional cell and tissue culture system |
US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
CA2018228C (fr) * | 1989-06-05 | 1996-02-27 | Nancy L. Parenteau | Systemes et milieu de culture cellulaire |
US5158934A (en) * | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
IL95429A (en) * | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
CA2080693C (fr) * | 1990-04-24 | 2001-11-27 | Mark Eisenberg | Equivalents composites de peau vivante |
US5891617A (en) * | 1993-09-15 | 1999-04-06 | Organogenesis Inc. | Cryopreservation of harvested skin and cultured skin or cornea equivalents by slow freezing |
US5599788A (en) * | 1994-07-01 | 1997-02-04 | Advanced Tissue Sciences | Method for accelerating skin wound healing with H3 protein |
US5733337A (en) * | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
US6121042A (en) * | 1995-04-27 | 2000-09-19 | Advanced Tissue Sciences, Inc. | Apparatus and method for simulating in vivo conditions while seeding and culturing three-dimensional tissue constructs |
US5792603A (en) * | 1995-04-27 | 1998-08-11 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts |
US5830708A (en) * | 1995-06-06 | 1998-11-03 | Advanced Tissue Sciences, Inc. | Methods for production of a naturally secreted extracellular matrix |
ES2229277T3 (es) * | 1995-06-07 | 2005-04-16 | Organogenesis Inc. | Composiciones de segmentos de fibra de colageno reconstituidos y metodos para su preparacion. |
WO1996039992A1 (fr) * | 1995-06-07 | 1996-12-19 | Advanced Tissue Sciences, Inc. | Appareil et procede pour steriliser, ensemencer, cultiver, stocker, expedier et tester des tissus cartilagineux de remplacement produits par assemblage |
US5843766A (en) * | 1995-06-07 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Apparatus for the growth and packaging of three dimensional tissue cultures |
MX9705540A (es) * | 1996-01-30 | 1997-10-31 | Organogenesis Inc | Metodo y diseño de empaque para la crioconservacion y almacenamiento de equivalentes de tejido cultivado. |
US5842477A (en) * | 1996-02-21 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Method for repairing cartilage |
US5763267A (en) * | 1996-04-16 | 1998-06-09 | Advanced Tissue Sciences | Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures |
US5827729A (en) * | 1996-04-23 | 1998-10-27 | Advanced Tissue Sciences | Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue |
AU3214797A (en) * | 1996-05-28 | 1998-01-05 | Regents Of The University Of Michigan, The | Engineering oral tissues |
US5718012A (en) * | 1996-05-28 | 1998-02-17 | Organogenesis, Inc. | Method of strength enhancement of collagen constructs |
US5993844A (en) * | 1997-05-08 | 1999-11-30 | Organogenesis, Inc. | Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix |
JP4356053B2 (ja) * | 1998-06-05 | 2009-11-04 | オルガノジェネシス インク. | 生物工学により作成した血管移植片支持体補綴 |
EP1203074A4 (fr) * | 1999-06-29 | 2003-09-10 | J Alexander Marchosky | Compositions et procede de formation et de renforcement des os |
US6673603B2 (en) * | 2000-09-01 | 2004-01-06 | Modex Therapeutiques, S.A. | Cell paste comprising keratinocytes and fibroblasts |
-
2003
- 2003-02-21 AU AU2003219830A patent/AU2003219830A1/en not_active Abandoned
- 2003-02-21 WO PCT/US2003/005200 patent/WO2003072128A2/fr not_active Application Discontinuation
- 2003-02-24 US US10/372,999 patent/US20030180270A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2003219830A1 (en) | 2003-09-09 |
WO2003072128A3 (fr) | 2003-12-31 |
WO2003072128A2 (fr) | 2003-09-04 |
US20030180270A1 (en) | 2003-09-25 |
AU2003219830A8 (en) | 2003-09-09 |
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