WO2003071931A2 - Automatic bladder relief system - Google Patents
Automatic bladder relief system Download PDFInfo
- Publication number
- WO2003071931A2 WO2003071931A2 PCT/US2003/006011 US0306011W WO03071931A2 WO 2003071931 A2 WO2003071931 A2 WO 2003071931A2 US 0306011 W US0306011 W US 0306011W WO 03071931 A2 WO03071931 A2 WO 03071931A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- urine
- layer
- relief system
- transport
- collection
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
- A61F5/451—Genital or anal receptacles
- A61F5/455—Genital or anal receptacles for collecting urine or discharge from female member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/44—Devices worn by the patient for reception of urine, faeces, catamenial or other discharge; Portable urination aids; Colostomy devices
- A61F5/451—Genital or anal receptacles
- A61F5/453—Genital or anal receptacles for collecting urine or other discharge from male member
Definitions
- U.S. Patent 4,886,508 discloses a ladies' external catheter assembly, however this device does not use a vacuum pump for drainage or utilize a moisture sensor.
- U.S. Patent No. 4,610,675 (Triunfol, 1986) teaches a device for collecting fluid discharged from female organs that is designed solely for incontinent women, not female aircrew members and the design includes a pad, vacuum pump and liquid sensor, however, the pad is more invasive because it is formed of plastic and has ridges to move the labia to an open position for free flow of liquid.
- the vacuum pump of the Triunfol patent is powered by an electrical outlet and does teach battery operation of these devices.
- U.S. Patent No. 5,662,631 (Marx, Sept. 2, 1997) a male external catheter assembly with vacuum retention is disclosed wherein a male external catheter attachment incorporates a vacuum or a means to produce reduced pressure to aid in installing and keeping the device in place.
- U.S. Patent No. 5,499,977 (Marx, Mar. 19, 1996) teaches another form of male external catheter with vacuum assist utilizing a rubber bulb that functions as a vacuum. As such, the basic concept of bladder discharge collection systems and their use are disclosed.
- Urinary incontinence affects more than 13 million Americans in community and institutional settings. Thirty-eight percent of non-institutionalized patients older than 60 years of age experienced urinary incontinence, and almost 50 percent of institutionalized patients. The annual costs of bladder control problems in the United States for people older than 65 years of age was estimated at $26.3 billion in 1995, or $3,565 per affected person. Many incontinent males use commercially available diapers, which cannot contain urine from multiple urinations, and become heavy and uncomfortable when wet.
- An automated or semi-automated bladder relief device is important not just for the aircrew member's comfort, health and safety, but also for the safety of the aircraft and squadron.
- the system will significantly reduce the pilot's distraction or downtime during bladder relief, which will improve pilot and aircraft safety.
- the present invention may also be effectively used by passengers in aircraft without toilet facilities, glider pilots, non-ambulatory patients, incontinent adults, astronauts, rescue workers in hazmat suits, and long-distance truckers and race car drivers.
- the present invention provides an apparatus that has been designed to automatically or semi-automatically collect urine in an environmentally challenging setting in a tikary, safe and comfortable manner which are improvements which are patently distinct over similar devices and methods which may already be patented or commercially available.
- the general purpose of the present invention which will be described subsequently in greater detail, is to provide a field designed apparatus and method of use that incorporates the present invention. There are many additional novel features directed to solving problems not addressed in the prior art.
- the present invention generally comprises a secure gender specific leakproof urine collection means, a fluid sensing unit, a suction means, and a storage and disposal means.
- the present invention provides an automated or semi-automated collection system with a large urinary storage capacity. Also, unlike prior art this invention does provide a comfortable collection system that requires no manipulation to utilize leaving the user's hand free for vital tasks; the present invention also provides for ease of set up, use, urine storage and disposal; and the present invention also provides an advancement in ecological protection by eliminating the need for disposal of environmentally damaging and bulky diaper materials.
- FIG. 1 is a perspective view of the female user embodiment.
- FIG.2 is a perspective view of the invention attached to a user and in use.
- FIG. 3 is an expanded cut-away perspective view of the female pad of the female user embodiment depicted in FIG. 1.
- FIG. 4 is a perspective view of the male user embodiment.
- FIG. 5 is a cut-away perspective view of the male cup of the male user embodiment depicted in FIG. 4.
- FIG. 6 is a cut-away perspective view of the suction control unit.
- FIG. 7 is a cut-away perspective view of the flow chamber.
- the Suction Control Unit (1) is a re-usable piece of hardware containing a suction vacuum pump (2), DC motor (5), rechargeable battery pack (7) and recharge circuitry (9).
- a built-in, battery-powered suction vacuum pump (2) sucks the urine from the Male Cup (57) in the male user embodiment and Female Pad (11) of the female user embodiment through a suction hose (13) and deposits the collected fluid into a Urine Collection Bag (3).
- Quick-disconnect hose couplings (17) connect and disconnect the Urine Collection Bag (3) and suction hose (13) from the Suction Control Unit (1).
- the Suction Control Unit (1) has two modes of operation: one power "ON/OFF" button (19) and one button that turns the unit "ON" and then "OFF' after a timed interval (21 ).
- a small, high-power DC motor is used, similar to those used in cordless vacuum cleaners.
- the DC motor (5) spins the vacuum pump impeller (23) to provide the suction required to draw the urine from the urine cavity (56) of the Male Cup (57).
- the system uses a filter (25) of charcoal or other material to deodorize the exhaust air.
- a battery pack (27) of rechargeable Nickel-Metal Hydride (NIMH) batteries are used to provide the power supply for the DC motor (5).
- a two-digit LCD Status Display (29) with backlight indicates the amount of time remaining in the battery charge, and the number of bladder relieves left in the power supply charge.
- NIMH Nickel-Metal Hydride
- a flow chamber (31) is contained in the Suction Control Unit (5).
- the flow chamber (31) begins at the Suction Control Unit Air/Liquid Inlet (33) and ends at both the Suction Control Unit Liquid Outlet (35) and the Suction Control Unit air exhaust outlet (37).
- This flow chamber (31) separates moisture from the vacuum airflow and channels the liquid to the Suction Control Unit Liquid Outlet (35) and the air to the Suction Control Unit Air Exhaust Outlet (37).
- the Suction Control Unit Air Exhaust Outlet (37) is fitted with a deodorizing air Filter (25). 2. Male Cup
- the Male Cup (57) is a disposable soft cup, approximately the same size and shape as a men's athletic protective cup.
- Figure 5 shows a cut-away view of a Male Cup (37).
- the cup has four layers: a facing layer (39M), wicking layer (41 M), urine collection layer (43M) and Moisture Proof Outer Layer (45M).
- the Moisture Proof Outer Layer (45M) is attached to and contains the facing layer (39M), wicking layer (41M), urine collection layer (43 M) along the edges thereof by means of the Outer Layer Wall (46M).
- a Urine Cavity (56) is defined by the urine collection layer (43M) and the Moisture Proof Outer Layer (45M) in the inside cup area (53M).
- the facing layer (39M), which lies against the skin, is made of a soft, non-woven, non-absorbent polymer.
- the wicking layer (41M) is made of a woven polymer. It pulls moisture away from the facing layer (39M) and prevents it from going back through the facing layer (39M), much like a one-way fluid check valve.
- the urine collection layer (43M) is made of an open cell foam material or other material capable of collecting fluid, and provides a Urine Cavity (56) in its placement juxtaposed to the Moisture Proof Outer Layer (45M) for the vacuum suction airflow produced by the Suction Vacuum Pump (2) to suck fluids and moisture out of the Male Cup (57) and away from the body.
- One-way airflow inlet holes (48) in the top of the Male Cup (57) facilitate the evacuation of liquids and provide air flow for drying the Male Cup's (57) layers.
- An isolation membrane (50) made of a thin, flexible material such as silicon rubber comfortably keeps a man's penis inside the Male Cup (57) compartment and prevents any leaking.
- the cup front (52) is made of a stretchable material such as silicon rubber that opens automatically to accommodate size changes.
- the suction hose (13) at the front of the Male Cup (57) is connected to the 5 Suction Control Unit (1).
- the Suction Control Unit (1) sucks all fluids from the Male Cup (57) through the suction hose (13) and deposits them into the Urine Collection Bag (3).
- the flexible, disposable suction hose (13) is outfitted with a quick-disconnect plug (51) on the end that connects to the Suction Control Unit (1).
- the suction hose (13) may be made of a l o convoluted, easily bendable material with spiral construction. This allows a smaller bending radius so that the suction hose (13) can be stowed in a person's clothing or flight suit while not in use, and permits all of the urine to drain out of the suction hose (13).
- the Moisture-Proof Outer Layer (45M) of the Male Cup (57) is made of dense
- the system is compatible with many types of Urine Collection Bags (3)
- Urine Collection Bag (3) including a disposable plastic bag containing super absorbent polymer crystals with a 500 cc urine capacity, and a larger, 1600 cc capacity Urine Collection Bag (3). Users who do not want to wear a Urine Collection Bag (3) for a long period of time can use smaller Urine Collection Bags (3). A zip lock top on the smaller Urine Collection Bags (3) allows its use as a standard piddle pack. Users who prefer not 5 to change Urine Collection Bags (3) after each urination can wear a larger leg or pocket Urine Collection Bag (3). A quick-disconnect similar to the quick- disconnect plug (51) can also be built into the Urine Collection Bags (3) for easy attachment and replacement.
- the Suction Control Unit ( 1 ) can be packaged to double as a pilot' s kneeboard as depicted in Figure 2.
- the kneeboard is molded and adjustable to fit the curve of the thigh.
- the aircrew member can carry the Suction Control Unit (1) in his helmet bag or wear it strapped to a thigh without giving the appearance of wearing bladder relief equipment.
- the quick-disconnect plug (51) hose couplings allow aircrew members to wait until they are seated in their aircraft or until they have to urinate to connect the Urine Collection Bag (3) and the suction hose (13) of the Male Cup (57) to the Suction Control Unit (1).
- the size and shape of the Urine Collection Bag (3) is designed to fit within the limited confines of the aircraft cockpit and navigator's seat. Piddle packs used by some male pilots are too long and difficult to open to its full length in a cockpit.
- the Suction Control Unit (1) (i.e. with concealed hoses).
- the Suction Control Unit (1) can be mounted to the person's wheelchair and the hoses concealed under the person's clothing. Many urinary incontinent adults are not in wheelchairs, but are bedridden.
- a larger urine collection bag (3) that does not contain super-absorbent polymer can be attached to the Suction Control Unit (1) that can be emptied and reused.
- a quiet Suction Control Unit (1) can be housed in a fanny pack that can also hold a concealed Urine Collection Bag (3).
- the Suction Control Unit (1) is a reusable piece of hardware containing a suction vacuum pump (2), DC motor (5), rechargeable battery pack (7) and recharge circuitry (9).
- a built-in, battery-powered suction vacuum pump (2) sucks the urine from the Female Pad (11) through a suction hose (13) at the front of pad and deposits the urine into a Urine Collection Bag (3).
- Quick-disconnect hose couplings (17) connect and disconnect the Urine Collection Bag (3) and the suction hose (13)from the Suction Control Unit (1).
- the Suction Control Unit (1) has two modes of operation: one power "ON/OFF" button (19) and one button that turns the unit "ON” and then "OFF” after a timed interval (21).
- a small, high-power DC motor (5) is used, similar to those used in cordless vacuum cleaners.
- the DC motor (5) spins the vacuum pump impeller (23) to provide the suction required to draw the urine from the Female Pad (11).
- the system uses a filter (25) of charcoal or other material to deodorize the exhaust air.
- a battery pack (27) of rechargeable Nickel-Metal Hydride (NIMH) batteries are used to provide the power supply for the DC motor.
- a two-digit LCD Status Display (29) with backlight indicates the amount of time remaining in the battery charge, and the number of bladder relieves left in the power supply charge.
- the recharge circuitry allows the battery pack (27) to be plugged into a wall outlet for recharging without damaging the batteries.
- a flow chamber (31) is contained in the Suction Control Unit (1).
- the flow chamber (31) begins at the Suction Control Unit Air/Liquid Inlet (33) and ends at 15 both the Suction Control Unit Liquid Outlet (35) and the Suction Control Unit Air Exhaust Outlet (37).
- This flow chamber (31) separates moisture from the vacuum airflow and channels the liquid to the Suction Control Unit Liquid Outlet (35) and the air to the Suction Control Unit Air Exhaust Outlet (37).
- the Suction Control Unit Air Exhaust Outlet (37) is fitted with a deodorizing air filter (25). 20 5.
- the Female Pad (11) is a disposable urine collection pad similar in size to a large feminine pad used for menstruation.
- Figure 3 shows an expanded view of the Female Pad (11).
- the Female Pad (11) has four layers: a facing layer (39), wicking layer (41), urine collection layer (43) and moisture-proof outer layer (45).
- the 5 Moisture Proof Outer Layer (45) is attached to and contains the facing layer (39), wicking layer (41), urine collection layer (43) along the edges thereof by means of the Outer Layer Wall (46).
- a Urine Cavity (56) is defined by the urine collection layer (43) and the Moisture Proof Outer Layer (45) in the inside cup area (53).
- the facing layer (39), which lies directly against the skin, is made of a soft, non- 0 woven, non-absorbent polymer.
- the wicking layer (41) is made of a woven polymer. It pulls moisture away from the facing layer (39) and prevents it from going back through the facing layer (39), much like a one-way fluid check valve.
- the urine collection layer (43) is made of open cell foam or other material or other material capable of collecting fluid, and provides a Urine Cavity (56) in its placement juxtaposed to the Moisture Proof Outer Layer (45) for the vacuum suction airflow produced by the Suction Vacuum Pump (2) to suck fluids and moisture out of the Female Pad (11) and away from the body.
- the Moisture Proof Outer Layer (45) a moisture-proof barrier made of soft, flexible plastic, wraps around the sides of the Female Pad (11) to prevent side leakage.
- One-way airflow inlet holes (47) in the back end of the Female Pad (11) facilitate the evacuation of liquids and provide air flow for drying the Female Pad's (11) layers.
- the Female Pad (l l) has a contoured shape for a more comfortable and reliable fit.
- Soft sealing strips (49) around the Female Pad (11) face perimeter prevent side leaks.
- the Female Pad (11) is held in place with a comfortable but sturdy undergarment available in women's apparel stores.
- the suction hose (13) at the front of the Female Pad (11) is connected to the Suction Control Unit (1).
- the Suction Control Unit (1) sucks all fluids from the Female Pad (11) through the suction hose (13) and deposits them into the Urine Collection Bag (3).
- the flexible, disposable suction hose (13) is outfitted with a quick-disconnect plug (51) on the end that connects to the Suction Control Unit (1).
- the suction hose (13) may be made of a convoluted, easily bendable material with spiral construction. This allows a smaller bending radius so that the suction hose (13) can be stowed in a person's clothing or flight suit while not in use, and permits all of the urine to drain out of the suction hose (13). 6.
- Urine Collection Bag in Female User Embodiment The system is compatible with many types of Urine Collection Bags (3) mcluding a disposable plastic bag containing super absorbent polymer crystals with a 500 cc urine capacity, and a larger, 1600 cc capacity bag. Users who do not want to wear a Urine Collection Bag (3) for a long period of time can use smaller Urine Collection Bags (3). Users who prefer not to change Urine Collection Bags (3) after each urination can wear a larger leg or pocket Urine Collection Bags (3). A quick-disconnect similar to the quick-disconnect plug (51) can also be built into the Urine Collection Bags (3) for easy attachment and replacement. Use By Female Air Crew Members
- the Suction Control Unit (1) can be packaged to double as a pilot's kneeboard as depicted in Figure 2.
- the kneeboard is molded and adjustable to fit the curve of the thigh.
- the aircrew member can carry the Suction Control Unit (1) in her helmet bag or wear it strapped to a thigh without giving the appearance of wearing bladder relief equipment.
- the quick-disconnect plug (51) suction hose (13) couplings allow aircrew members to wait until they are seated in their aircraft or until they have to urinate to connect the Urine Collection Bag (3) and the Female Pad (11) suction hose (13) to the Suction Control Unit (1).
- the size and shape of the Urine Collection Bag (13) is designed to fit within the limited confines of the aircraft cockpit and navigator's seat
- the Suction Control Unit (1) can be mounted to the person's wheelchair and the hoses concealed under the person's clothing. Many urinary incontinent adults are not in wheelchairs, but are bedridden. A larger urine collection bag (3) that does not contain super absorbent polymer can be attached to the Suction Control Unit (1) that can be emptied and reused. For ambulatory adults and children, a quiet Suction Control Unit (1) can be housed in a fanny pack that can also hold a concealed Urine Collection Bag (3).
- a moisture sensor (55) is installed in the Female Pad (11) to automatically activate the Suction Control Unit (1) when moisture is sensed in the urine cavity (56).
- the Suction Control Unit (1) could be mounted to the person's wheelchair and the suction hoses (13) concealed under the person's clothing. Many urinary incontinent adults are not in wheelchairs, but are bedridden. A larger urine collection bag (3) that does not contain super- absorbent polymer can be used that can be emptied by staff/care-givers and reused.
- a moisture sensor (55) can be installed in the Female Pad (11) and Male Cup (57) that will automatically activate the Suction
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nursing (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Sanitary Device For Flush Toilet (AREA)
- Moulds For Moulding Plastics Or The Like (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
- External Artificial Organs (AREA)
- Devices For Medical Bathing And Washing (AREA)
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR0307826-4A BR0307826A (en) | 2002-02-26 | 2003-02-25 | Automatic relief system, bladder type |
IL16368003A IL163680A0 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
NZ534498A NZ534498A (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
CA002476695A CA2476695A1 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
AU2003212440A AU2003212440A1 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
JP2003570684A JP2005518237A (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relaxation system |
KR10-2004-7013234A KR20040091663A (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
EP03709380A EP1478315A4 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
EA200400978A EA006587B1 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
MXPA04008311A MXPA04008311A (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system. |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35967202P | 2002-02-26 | 2002-02-26 | |
US60/359,672 | 2002-02-26 | ||
US10/369,240 US6706027B2 (en) | 2002-02-26 | 2003-02-19 | Automatic bladder relief system |
US10/369,240 | 2003-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003071931A2 true WO2003071931A2 (en) | 2003-09-04 |
WO2003071931A3 WO2003071931A3 (en) | 2004-02-19 |
Family
ID=27760555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/006011 WO2003071931A2 (en) | 2002-02-26 | 2003-02-25 | Automatic bladder relief system |
Country Status (14)
Country | Link |
---|---|
US (1) | US6706027B2 (en) |
EP (1) | EP1478315A4 (en) |
JP (1) | JP2005518237A (en) |
KR (1) | KR20040091663A (en) |
CN (1) | CN1289041C (en) |
AU (1) | AU2003212440A1 (en) |
BR (1) | BR0307826A (en) |
CA (1) | CA2476695A1 (en) |
EA (1) | EA006587B1 (en) |
IL (1) | IL163680A0 (en) |
MX (1) | MXPA04008311A (en) |
NZ (1) | NZ534498A (en) |
RU (1) | RU2004129287A (en) |
WO (1) | WO2003071931A2 (en) |
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US12121468B2 (en) | 2014-03-19 | 2024-10-22 | Purewick Corporation | Apparatus and methods for receiving discharged urine |
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KR100857897B1 (en) * | 2006-04-25 | 2008-09-10 | 한메딕스 주식회사 | Collection apparatus of the body fluid |
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- 2003-02-25 MX MXPA04008311A patent/MXPA04008311A/en unknown
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Also Published As
Publication number | Publication date |
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CN1638708A (en) | 2005-07-13 |
EA006587B1 (en) | 2006-02-24 |
IL163680A0 (en) | 2005-12-18 |
EP1478315A4 (en) | 2008-06-04 |
MXPA04008311A (en) | 2004-11-26 |
CN1289041C (en) | 2006-12-13 |
EA200400978A1 (en) | 2004-12-30 |
WO2003071931A3 (en) | 2004-02-19 |
RU2004129287A (en) | 2005-06-10 |
JP2005518237A (en) | 2005-06-23 |
CA2476695A1 (en) | 2003-09-04 |
US6706027B2 (en) | 2004-03-16 |
US20030163120A1 (en) | 2003-08-28 |
AU2003212440A1 (en) | 2003-09-09 |
KR20040091663A (en) | 2004-10-28 |
BR0307826A (en) | 2005-04-12 |
EP1478315A2 (en) | 2004-11-24 |
NZ534498A (en) | 2006-03-31 |
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